Amyloidosis cutis dyschromica: a rare pigmentary disorder.

abstract：:Many patients who present with patch and early plaque stage mycosis fungoides follow an indolent course and survive for many years following diagnosis. A certain subset of patients, however, have rapidly progressive disease leading to accelerated demise. We examined 21 histologic sections from initial biopsies taken f...

journal_title：Journal of cutaneous pathology

authors： Smoller BR,Detwiler SP,Kohler S,Hoppe RT,Kim YH

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:Despite its occasional unavailability, alcian blue has long been the stain of choice for the pathognomonic mucin-secreting cells of extramammary Paget's disease. Zirconyl hematoxylin is a recently developed substitute for alcian blue, which is made from common laboratory materials. METHODS:We have stained s...

journal_title：Journal of cutaneous pathology

authors： Smith AA,Silver TM

更新日期：2003-07-01 00:00:00

abstract：:Respiratory cysts are benign lesions lined by normal respiratory epithelium. There are few reported cases localized to the orbit, while those of the eyelid are exceedingly rare. Respiratory cysts usually arise either from a non-hereditary congenital malformation, where they are distinguished as choristomatous, or from...

journal_title：Journal of cutaneous pathology

authors： Yeh C,Atillasoy C,Seykora JT,Lee V

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Pigmentation is a characteristic clinical feature of basal cell carcinomas (BCCs) in Japanese patients. The pathogenesis of melanin pigment in pigmented BCCs is poorly understood. METHODS:We have combined the techniques of morphometric analysis and electron microscopy to assess accurately the morphologic as...

journal_title：Journal of cutaneous pathology

authors： Lao LM,Kumakiri M,Kiyohara T,Kuwahara H,Ueda K

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Sebaceous tumors are adnexal neoplasms showing sebocytic differentiation. They range from benign to malignant and are associated with Muir-Torre syndrome (MTS). Several clinical and histopathological features associated with MTS have been described. Sebaceous tumors with an overlying cutaneous horn are extre...

journal_title：Journal of cutaneous pathology

authors： Jhuang JY,Liao SL,Tsai JH,Chang HC,Kuo KT,Liau JY

更新日期：2014-08-01 00:00:00

abstract：:A case of an unusual benign apocrine hamartoma was studied by light microscopic, immunohistochemical, and electron microscopic methods. This tumor clinically showed a linear configuration and was located on the midline chest of a pubescent male. Microscopic studies revealed features of both a tubular apocrine adenoma ...

journal_title：Journal of cutaneous pathology

authors： Epstein BA,Argenyi ZB,Goldstein G,Whitaker D

更新日期：1990-02-01 00:00:00

abstract：:Xanthogranulomas are benign lesions composed of macrophages in which some of the cells have vacuolated cytoplasm. They commonly occur in children, referred to as juvenile xanthogranulomata, and are histopathologically characterized by the presence of Touton giant cells. Xanthogranuloma can also occur in adults. A woma...

journal_title：Journal of cutaneous pathology

authors： Cohen PR,Prieto VG

更新日期：2010-08-01 00:00:00

abstract：:Lymphomatoid granulomatosis (LG) is a rare Epstein-Barr virus (EBV)-associated B-cell lymphoproliferative disorder presenting in middle adulthood that nearly always affects the lungs and shows cutaneous involvement in up to 50% of cases. Skin lesions are present at the time of diagnosis in roughly one-third of patient...

journal_title：Journal of cutaneous pathology

authors： Rysgaard CD,Stone MS

更新日期：2015-03-01 00:00:00

abstract：:The three-dimensional morphology of six dermatofibromas was studied by scanning electron microscopy. Hypertrophic epidermal ridges covered with large keratinized cells overlay each dermal lesion. Small collagenous fibers in the tumors contrasted with the bundles of much larger collagenous fibers in the normal dermis p...

journal_title：Journal of cutaneous pathology

authors： Wilborn WH,Montes LF

更新日期：1979-08-01 00:00:00

abstract：:The expression and localization of connexin 43 (Cx43) were investigated in normal human epidermis, pilosebaceous apparatus, basal cell carcinoma, and squamous cell carcinoma by immunofluorescence as well as by immunoelectron microscopy. In the normal epidermis the immunofluorescence was weak in the basal layer, increa...

journal_title：Journal of cutaneous pathology

authors： Tada J,Hashimoto K

更新日期：1997-11-01 00:00:00

abstract：:Cutaneous leiomyomata, which are benign smooth muscle neoplasms, commonly present as dermal-based nodules or papules with smooth borders and firm consistency. Digital, particularly subungual leiomyomata are quite rare. A 16-year-old female presented to nail clinic complaining of discoloration of the lunula of the left...

journal_title：Journal of cutaneous pathology

authors： Komforti M,Selim MA,Bellet JS

更新日期：2016-04-01 00:00:00

abstract：:Chronic lymphocytic leukaemia (CLL) shows cutaneous involvement in 2% of cases. Merkel cell carcinoma (MCC) is a rare primary cutaneous epithelial neoplasm most commonly found in sun-exposed sites in elderly male Caucasians. A 66-year-old man presented with a 2-month history of a purple painless 2 cm tumor on the scal...

journal_title：Journal of cutaneous pathology

authors： Craig PJ,Calonje JE,Harries M,Stefanato CM

更新日期：2009-06-01 00:00:00

abstract：:Twenty-nine cases of histiocytic neoplasms, some resembling juvenile xanthogranuloma (JXG) and others resembling reticulohistiocytoma (RH), were evaluated. Immunohistochemical stains were performed. In this series, seven cases were identified that expressed S-100 protein positive cells. The S-100 positive cells were p...

journal_title：Journal of cutaneous pathology

authors： Tomaszewski MM,Lupton GP

更新日期：1998-03-01 00:00:00

abstract：:Psoriasis is characterized by immune activation, increased proliferation and abnormal differentiation of keratinocytes. The reported anti-psoriatic mechanisms of action in vivo of vitamin D analogues include reduction of keratinocyte proliferation and induction of keratinocyte terminal differentiation. We investigated...

journal_title：Journal of cutaneous pathology

authors： Lu I,Gilleaudeau P,McLane JA,Heftler N,Kamber M,Gottlieb S,Krueger JG,Gottlieb AB

更新日期：1996-10-01 00:00:00

abstract：BACKGROUND:Neurothekeoma is a benign tumor of putative peripheral nerve sheath origin. It occurs in a myxoid (classic) variant, cellular variant, and intermediate (mixed) variant. Cellular neurothekeoma (CNT) usually involves the head and neck or extremities of young patients. Histologically, CNT can be confused with m...

journal_title：Journal of cutaneous pathology

authors： Fullen DR,Lowe L,Su LD

更新日期：2003-02-01 00:00:00

abstract：:Dermatomyositis, a connective tissue disease syndrome where antibodies to the endothelium of the microvasculature of the skin, muscle and lung are implicated in lesional propagation, is characterized by photodistributed erythema, heliotrope rash, Gottron's papules, muscle weakness and interstitial pulmonary fibrosis. ...

journal_title：Journal of cutaneous pathology

authors： Magro CM,Schaefer JT,Waldman J,Knight D,Seilstad K,Hearne D

更新日期：2008-01-01 00:00:00

abstract：:CD44, a family of closely related glycoproteins generated by alternative splicing, as well as the increased beta 1,6-branching of Asn-linked oligosaccharides (beta 1,6-branches), have been implicated in tumor progression and metastasis. We have investigated the expression of CD44 standard (CD44s), various CD44 splice ...

journal_title：Journal of cutaneous pathology

authors： Seelentag WK,Böni R,Günthert U,Futo E,Burg G,Heitz PU,Roth J

更新日期：1997-04-01 00:00:00

abstract：:Agminated, or grouped Spitz nevi are a curious expression of nevomelanocytic growth; and represent an uncommon manifestation of these nevi. We encountered an example of agminated Spitz nevi present at birth, which showed progression and rapid growth over months. All showed histologic Spitz nevus features. Avidin-bioti...

journal_title：Journal of cutaneous pathology

authors： Palazzo JP,Duray PH

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND:Cutaneous mesothelioma is rare but may occur following local surgical procedures for visceral mesothelioma or as a metastasis. METHODS:A patient with pleural mesothelioma, who developed papules within chest wall scars, 14 and 15 months after pleural biopsy and thoracentesis, respectively, is reported. RESU...

journal_title：Journal of cutaneous pathology

authors： Shieh S,Grassi M,Schwarz JK,Cheney RT

更新日期：2004-08-01 00:00:00

abstract：:In the past decades, the incidence of melanoma has been reported to rise in epidemic proportions. The chief reason for that pseudo-epidemic is improved criteria for diagnosis that allow melanomas to be recognized far more accurately and at earlier stages. The rising number of melanomas diagnosed has resulted in increa...

journal_title：Journal of cutaneous pathology

authors： Weyers W

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Apoptosis is important for maintenance of tissue homeostasis and often dysregulated in cutaneous neoplasms. The apoptosis inhibitor survivin is expressed in melanoma and non-melanoma skin cancers and benign keratinocytic lesions. Its expression has not been studied in melanocytic nevi. OBJECTIVE:We determin...

journal_title：Journal of cutaneous pathology

authors： Florell SR,Bowen AR,Hanks AN,Murphy KJ,Grossman D

更新日期：2005-01-01 00:00:00

abstract：:Two young patients with conjunctival compound nevi are presented to illustrate two types of abnormalities that lead to difficulty in distinction of these nevi from invasive melanomas. In Case 1, inflammation is associated with disruption of the nevus cell architecture and cytologic atypia. In Case 2, the occurrence of...

journal_title：Journal of cutaneous pathology

authors： Kabukçuoğlu S,McNutt NS

更新日期：1999-05-01 00:00:00

abstract：:CD8+ T-cell lymphomas presenting in the skin are rare. We describe the clinical and histological features of 18 patients with CD8+ cutaneous T-cell tumors, which have been divided into four groups. Seven patients had precedent long histories of rashes, which progressively spread in a presentation similar to that of CD...

journal_title：Journal of cutaneous pathology

authors： Lu D,Patel KA,Duvic M,Jones D

更新日期：2002-09-01 00:00:00

abstract：:A histologically unique condition of the sweat duct was found in a miliaria-like papular eruption on the extensor surfaces of extremities of a 41-year-old female patient. The hypertrophic epithelium of the sweat duct wall consisted of extensively vacuolated clear cells. There was mild hyperkeratosis around the sweat d...

journal_title：Journal of cutaneous pathology

authors： Izaki S,Kono E,Hirai A,Kitamura K

更新日期：1994-06-01 00:00:00

abstract：:Long-term survivors of harlequin ichthyosis (HI) have raised a controversy over the differences between HI and lamellar ichthyosis (LI). Abnormal lamellar granules and the failure of conversion from profilaggrin to filaggrin have been reported in HI. On the other hand, malformation of the cornified cell envelope as a ...

journal_title：Journal of cutaneous pathology

authors： Akiyama M,Yoneda K,Kim SY,Koyama H,Shimizu H

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:p53 mutations are etiologically associated with the development of squamous cell carcinomas (SCCs) or with exposure to specific carcinogens. The study was conducted to examine the relationship of immunohistochemistry (IHC) scores between altered p53 protein expression in relation to patient's habits and hist...

journal_title：Journal of cutaneous pathology

authors： Bukhari MH,Niazi S,Chaudhry NA

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:The Wnt signaling pathway has been implicated in the pathogenesis of pilomatrical tumors. Lymphoid enhancer-binding factor 1 (LEF-1) is a downstream component of this pathway, and Caudal-related homeobox transcription factor 2 (CDX2) has been postulated to regulate it, but little is known about expression of...

journal_title：Journal of cutaneous pathology

authors： Tumminello K,Hosler GA

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Trichilemmal (pilar) cysts are common skin lesions that usually occur on the scalp of elderly women. They differentiate towards the follicular outer root sheath epithelium and show trichilemmal keratinization. Proliferating trichilemmal tumor (PTT) shows features of typical pilar cyst, but additionally shows...

journal_title：Journal of cutaneous pathology

authors： Folpe AL,Reisenauer AK,Mentzel T,Rütten A,Solomon AR

更新日期：2003-09-01 00:00:00

abstract：:Anaplastic large cell lymphoma (ALCL) is a CD30+ T-cell non-Hodgkin lymphoma with 2 main clinical presentations: primary cutaneous ALCL (pcALCL) and systemic ALCL (sALCL). While rare cases of myxoid sALCL have been reported, there are no previous cases of myxoid pcALCL reported. We present 2 unusual cases of pcALCL sh...

journal_title：Journal of cutaneous pathology

authors： Fernandez-Flores A,Eginli A,Cassarino DS

更新日期：2017-09-01 00:00:00

abstract：:The nuclei of spindle and epithelioid cell nevus (SECN) cells often contain inclusions. To determine the origin and pathogenesis of the nuclear inclusions, 12 cases of SECN were electron microscopically examined. True inclusions, pseudoinclusions, and electron-lucent areas were frequently found in the nuclei of SECN c...

journal_title：Journal of cutaneous pathology

authors： Sakamoto F,Ito M,Sato Y

更新日期：1990-04-01 00:00:00