Radiation port xanthogranuloma: solitary xanthogranuloma occurring within the irradiated skin of a breast cancer patient-report and review of cutaneous neoplasms developing at the site of radiotherapy.

abstract：INTRODUCTION:The term spitzoid melanoma (SM) is reserved for a rare group of tumors with striking resemblance to Spitz nevus, often developing in children diagnosed in retrospect after the development of metastases. OBJECTIVES:To determine the biological significance of SM and to analyze the effectiveness of adjuvant ...

journal_title：Journal of cutaneous pathology

authors： Paradela S,Fonseca E,Pita S,Kantrow SM,Goncharuk VN,Diwan H,Prieto VG

更新日期：2009-07-01 00:00:00

abstract：:Early cutaneous Lyme disease, erythema migrans, may show different histopathologic patterns. The intent of this case series is to raise awareness of these findings to prevent misdiagnosis and keep this entity in the differential. Erythema migrans develops after a tick bite and subsequent infection with the spirochete,...

journal_title：Journal of cutaneous pathology

authors： Miraflor AP,Seidel GD,Perry AE,Castanedo-Tardan MP,Guill MA,Yan S

更新日期：2016-01-01 00:00:00

abstract：:Erythrodermic cutaneous T-cell lymphoma (E-CTCL) is the cause of less than 5% of all cases of generalized erythroderma. A methodical evaluation of skin, blood, and lymph node samples using standard histology, immunohistochemistry (IHC), flow cytometry (FC), and molecular analysis for evidence of a dominant T-cell clon...

journal_title：Journal of cutaneous pathology

authors： Vonderheid EC

更新日期：2006-02-01 00:00:00

abstract：:Biopsies from a 5-year-old girl with dermatomyositis and universal calcinosis were studied histopathologically and by means of electron optical techniques. The dermis was infiltrated by fibroblasts, lymphocytes and plasma cells. In the lower part of the dermis, dense basophilic areas were present. In the vicinity of t...

journal_title：Journal of cutaneous pathology

authors： Nielsen AO,Johnson E,Hentzer B,Kobayasi T

更新日期：1979-12-01 00:00:00

abstract：AIM:Adnexal tumors with divergent lines of differentiation are uncommon. Herein, I report a hamartoma of the eyelid with follicular, sebaceous and apocrine differentiation that exhibited prominent melanin pigmentation. METHODS:A 63-year-old white woman had a nodule present on her left upper eyelid for 15 years. The no...

journal_title：Journal of cutaneous pathology

authors： Proia AD

更新日期：2007-11-01 00:00:00

abstract：:We present a case of a 64-year-old man with refractory acute myeloid leukemia and trisomy 8 who developed leukemia cutis. Interphase fluorescence in situ hybridization (FISH) was performed on a paraffin-embedded skin section. FISH confirmed a population of cells with trisomy 8 in the blastic infiltrates involving the ...

journal_title：Journal of cutaneous pathology

authors： Shvartsbeyn M,Meehan SM,Gu P,Nierodzik ML,Perle MA

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Tumor-infiltrating lymphocytes (TILs) are considered to play an important role in the antitumoral immune response. The presence and percentage of CD8-positive tumor-infiltrating T cells have been shown to correlate with differentiation and prognosis in various neoplasms. The aim of this study was to determin...

journal_title：Journal of cutaneous pathology

authors： Kamarashev J,Schaerer L,Burg G,Schmid MH,Müller B,Kempf W

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Primary cutaneous apocrine cribriform carcinoma (PCACC) is a rare tumor, clinically appearing as a solitary nodule, mostly involving extremities of females and this lesion usually raises a differential diagnosis with metastatic cribriform carcinomas, especially breast cancer. OBJECTIVE:To study GATA3 expres...

journal_title：Journal of cutaneous pathology

authors： Llamas-Velasco M,Pérez-Gónzalez YC,Daudén E,Rütten A

更新日期：2018-05-01 00:00:00

abstract：BACKGROUND:Nickel can induce cellular and nuclear damages responsible for chronic diseases, like allergic contact dermatitis (ACD). We previously showed that matrix metalloproteinase-2 (MMP-2) gene expression was induced by nickel in nontumorigenic human keratinocytes cell line (HaCat). OBJECTIVE:To investigate the si...

journal_title：Journal of cutaneous pathology

authors： Perfetto B,Lamberti M,Giuliano MT,Canozo N,Cammarota M,Baroni A

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:Cutaneous lymphatic malformations represent a group of heterogeneous diseases caused by developmental defects of lymphatic system. OBJECTIVE:The purpose of this study was to report the clinical, histopathological and immunohistochemical features of a distinctive lymphatic malformation. METHODS:Twelve patie...

journal_title：Journal of cutaneous pathology

authors： Wang L,Gao T,Wang G

更新日期：2013-07-01 00:00:00

abstract：:Desmoplastic melanoma can be difficult to distinguish from desmoplastic melanocytic nevi both clinically and histopathologically. Several attempts have been made to explore the use of ancillary studies to facilitate this distinction. Prior work has suggested that immunohistochemical expression of p16 could help distin...

journal_title：Journal of cutaneous pathology

authors： Blokhin E,Pulitzer M,Busam KJ

更新日期：2013-09-01 00:00:00

abstract：:The term hemangioendothelioma has been used in recent years to name a heterogeneous group of vascular neoplasms, intermediate in both biological behavior and histopathologic appearance between benign tumors (hemangiomas) and frankly malignant tumors (angiosarcomas). Thus, within the spectrum of hemangioendothelioma ha...

journal_title：Journal of cutaneous pathology

authors： Requena L,Luis Díaz J,Manzarbeitia F,Carrillo R,Fernández-Herrera J,Kutzner H

更新日期：2008-02-01 00:00:00

abstract：:Patients with primary immunodeficiency are at increased risk for malignancy, especially hematologic neoplasms. This paper reports a unique case of a 47-year-old man with X-linked agammaglobulinemia who presented with progressive asymptomatic violaceous papules and plaques on his face, hands, and trunk for 1 year. Skin...

journal_title：Journal of cutaneous pathology

authors： Daou H,Hatch LA,Weinkle A,Morey GE,Messina J,Zhang X,Sokol L,Seminario-Vidal L

更新日期：2020-09-03 00:00:00

abstract：BACKGROUND:Telomerase plays a role in the immortalization of cells and carcinogenesis. Previous studies have yielded conflicting results on whether human telomerase RNA (hTER) expression differs in nevi, atypical nevi and melanomas using polymerase chain reaction-based telomeric repeat amplification protocol or in situ...

journal_title：Journal of cutaneous pathology

authors： Fullen DR,Zhu W,Thomas D,Su LD

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Gene expression profiling of melanoma and nevic tissue has demonstrated that pleiotrophin (PTN) is significantly overexpressed in human melanomas. METHODS:To further evaluate PTN expression in melanocytic lesions, protein immunohistochemistry was performed on the spectrum of melanocytic lesions. RESULTS:Me...

journal_title：Journal of cutaneous pathology

authors： Wu H,Barusevicius A,Babb J,Klein-Szanto A,Godwin A,Elenitsas R,Gelfand JM,Lessin S,Seykora JT

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:We encountered a distinctive pattern of dysplastic intraepidermal melanocytic proliferation, which defies classification as a dysplastic melanocytic nevus, but in which the morphologic features fall short of a diagnosis of melanoma in situ. We designate such lesions as de novo intraepidermal epithelioid mela...

journal_title：Journal of cutaneous pathology

authors： Sachdeva M,Frambach GE,Crowson AN,Deng AC,Mihm MC Jr,Magro CM

更新日期：2005-10-01 00:00:00

abstract：:The development of cancer involves epithelial-stromal interactions. Alterations in the synthesis and deposition of type I and III collagens are related to the tumor morphology. Skin carcinogenesis in experimental animals provides a reliable model for the development of neoplasia. Ultraviolet (UV) irradiation is the ma...

journal_title：Journal of cutaneous pathology

authors： Stenbäck F,Mäkinen MJ,Jussila T,Kauppila S,Risteli J,Talve L,Risteli L

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Apocrine carcinomas are rare, the immunohistochemical characterizations that are incomplete. The purpose of this study was to determine the immunohistochemical characteristics of mucin core proteins and keratins in apocrine carcinoma, extramammary Paget's disease (EMPD) and apocrine nevus. METHODS:We report...

journal_title：Journal of cutaneous pathology

authors： Miyamoto T,Inoue S,Adachi K,Takada R

更新日期：2009-05-01 00:00:00

abstract：:Nivolumab is a programmed cell death receptor-1 (PD-1) antibody used in the treatment of metastatic or unresectable melanoma. Cutaneous reactions are the most common adverse events reported with these agents and are rarely severe or life-threatening. Here we present a case report describing the clinicopathological fin...

journal_title：Journal of cutaneous pathology

authors： Vivar KL,Deschaine M,Messina J,Divine JM,Rabionet A,Patel N,Harrington MA,Seminario-Vidal L

更新日期：2017-04-01 00:00:00

abstract：:Human hair follicles (HF) and sebaceous glands (SG) were assessed for the presence and distribution of the cytochrome P-450-aromatase (AR) and 3B-hydroxysteroid dehydrogenase (3B-HSD) enzymes. Immunohistochemical methods were used to examine both enzymes in male and female human skin specimens at various ages and diff...

journal_title：Journal of cutaneous pathology

authors： Sawaya ME,Penneys NS

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:The diagnosis of tuberculoid leprosy is often difficult on hematoxylin and eosin (H&E) due to the absence of demonstrable nerve destruction. This study evaluates the utility of S-100 staining in identifying nerve fragmentation and differentiation of tuberculoid leprosy from other cutaneous granulomatous dise...

journal_title：Journal of cutaneous pathology

authors： Gupta SK,Nigam S,Mandal AK,Kumar V

更新日期：2006-07-01 00:00:00

abstract：:Traditionally, the pigmented purpuric eruptions (PPE) have been subdivided into four histologic categories, based upon variations in histologic pattern and clinical morphologies. In recent years, it has become apparent that the lesions behave similarly, and this family of eruptions has become grouped under the term PP...

journal_title：Journal of cutaneous pathology

authors： Smoller BR,Kamel OW

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND:Histopathology is often essential to establish an accurate diagnosis. Pathology laboratories are scarce in most Sub-Saharan Africa where dermatopathology is a developing field. In resource-poor countries, most specimens are analyzed only after hematoxylin and eosin staining. The availability of special stain...

journal_title：Journal of cutaneous pathology

authors： Kiprono S,Muchunu J,Beltraminelli H

更新日期：2016-03-01 00:00:00

abstract：:Lobular capillary hemangioma, which is also named as pyogenic granuloma, is a common vascular proliferation of skin and mucous membranes. Hormonal influence in the development of lobular capillary hemangioma on the mucosal surfaces has been demonstrated but for cutaneous lesions located on the skin, this association h...

journal_title：Journal of cutaneous pathology

authors： Demir Y,Demir S,Aktepe F

更新日期：2004-01-01 00:00:00

abstract：:Another histological variant of basal cell carcinoma (BCC) is described. This clear-cell variant appeared as a recurrent lesion on the back of an elderly man. Histological examination revealed that part of the tumor was composed of clear cells with faintly eosinophilic cytoplasm. Degenerative changes were present, alo...

journal_title：Journal of cutaneous pathology

authors： Oliver GF,Winkelmann RK

更新日期：1988-12-01 00:00:00

abstract：:Three selected cases of transient acantholytic dermatosis were studied because of their definitive correlation with sweating due to fever and/ or bed-ridden situations. Biopsy specimens were serially sectioned and acantholysis was found in the acrosyringium or traced to connect to the acrosyringium in all biopsy speci...

journal_title：Journal of cutaneous pathology

authors： Hashimoto K,Moiin A,Chang MW,Tada J

更新日期：1996-04-01 00:00:00

abstract：:A 60-year-old female and a 59-year-old male each presented with a solitary circumscribed patch of depressed skin of the right thenar palm and right sole, respectively. Both lesions were present for approximately 30 years without a history of trauma or other inciting incident. Histologically, the lesions showed a well-...

journal_title：Journal of cutaneous pathology

authors： Barry CI,Glusac EJ,Kashgarian M,Gwin K,McNiff JM

更新日期：2008-05-01 00:00:00

abstract：:Angioimmunoblastic T-cell lymphoma (AITL) is an aggressive form of peripheral T-cell lymphoma, characterized by systemic symptoms, diffuse lymphadenopathy, hepatosplenomegaly and immunodysregulation. Half of AITL is associated with cutaneous symptoms, but only few cases with bullous eruption have been described. Assoc...

journal_title：Journal of cutaneous pathology

authors： Colmant C,Camboni A,Dekeuleneer V,Marot L,Dachelet C,Baeck M

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Histopathologic examination is sometimes inadequate for accurate and reproducible diagnosis of certain melanocytic neoplasms. As a result, more sophisticated and objective methods have been sought. The goal of this study was to identify a gene expression signature that reliably differentiated benign and mali...

journal_title：Journal of cutaneous pathology

authors： Clarke LE,Warf MB,Flake DD 2nd,Hartman AR,Tahan S,Shea CR,Gerami P,Messina J,Florell SR,Wenstrup RJ,Rushton K,Roundy KM,Rock C,Roa B,Kolquist KA,Gutin A,Billings S,Leachman S

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Hypertrophic lichen planus (LP) is a variant of LP favoring the lower extremities and showing prominent epidermal hyperplasia and hyperorthokeratosis. Contrary to dogma that eosinophils are rare in LP and variants, we noticed that some cases of hypertrophic LP have eosinophils in the absence of drug history....

journal_title：Journal of cutaneous pathology

authors： Alomari A,McNiff JM

更新日期：2014-04-01 00:00:00