Trisomy 8 in myeloid leukemia cutis confirmed by fluorescence in situ hybridization analysis.

Abstract:

:We present a case of a 64-year-old man with refractory acute myeloid leukemia and trisomy 8 who developed leukemia cutis. Interphase fluorescence in situ hybridization (FISH) was performed on a paraffin-embedded skin section. FISH confirmed a population of cells with trisomy 8 in the blastic infiltrates involving the skin. This case illustrates a novel application of interphase FISH to confirm the diagnosis of leukemia cutis.

journal_name

J Cutan Pathol

authors

Shvartsbeyn M,Meehan SM,Gu P,Nierodzik ML,Perle MA

doi

10.1111/j.1600-0560.2012.01981.x

subject

Has Abstract

pub_date

2012-11-01 00:00:00

pages

1026-9

issue

11

eissn

0303-6987

issn

1600-0560

journal_volume

39

pub_type

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