Cornified cell envelope proteins and keratins are normally distributed in harlequin ichthyosis.

abstract：:We report a case of a 68-year-old man with cutaneous leiomyosarcoma of the penis. Leiomyosarcoma of the penis is an extremely rare neoplasm that usually presents in middle to old age, and to our knowledge only approximately 30 cases have been reported in the literature to date. This is an important diagnosis in the di...

journal_title：Journal of cutaneous pathology

authors： Cibull TL,Thomas AB,Badve S,Billings SD

更新日期：2008-06-01 00:00:00

abstract：:Epidermal growth factor (EGF) and transforming growth factor alpha (TGF alpha) are important keratinocyte mitogens. Their effects are mediated by a cell membrane receptor (EGFR), quantitative and qualitative abnormalities of which may be responsible for deranged keratinocyte proliferation and differentiation. We have ...

journal_title：Journal of cutaneous pathology

authors： Groves RW,Allen MH,MacDonald DM

更新日期：1992-02-01 00:00:00

abstract：:Xanthogranulomas are benign lesions composed of macrophages in which some of the cells have vacuolated cytoplasm. They commonly occur in children, referred to as juvenile xanthogranulomata, and are histopathologically characterized by the presence of Touton giant cells. Xanthogranuloma can also occur in adults. A woma...

journal_title：Journal of cutaneous pathology

authors： Cohen PR,Prieto VG

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Epidermal nevi (in the broad sense of epithelial nevi) may give rise to benign or malignant skin tumors. They may also be associated with anomalies of other organ systems in an epidermal nevus syndrome. RESULTS:This article describes a preterm infant with nevus sebaceus of the scalp and face, a large turban...

journal_title：Journal of cutaneous pathology

authors： Regalado JJ

更新日期：2003-10-01 00:00:00

abstract：:Dermatofibrosarcoma protuberans is a low-grade sarcoma of the skin with well characterized clinical and histopathological features. The lesion frequently appears as a plaque on the trunk or on the extremities of middle-aged adults. Microscopically, the tumor is composed of monomorphous spindle cells arranged in storif...

journal_title：Journal of cutaneous pathology

authors： Diaz-Cascajo C,Weyers W,Borghi S

更新日期：1998-09-01 00:00:00

abstract：:Primary cutaneous extranodal marginal zone lymphoma (MZL) of mucosa-associated lymphoid tissue (MALT) represents a monoclonal B-cell neoplasm that typically presents with papules, plaques or nodules. We describe a patient with a primary cutaneous MALT lymphoma with unusual clinical features and an unusual immunophenot...

journal_title：Journal of cutaneous pathology

authors： Edinger JT,Lorenzo CR,Breneman DL,Swerdlow SH

更新日期：2011-09-01 00:00:00

abstract：:The histological picture of molluscum contagiosum (MC) is well known: the epidermis grows down into the dermis as multiple, closely packed pear-shaped lobules. The epithelial cells of the outermost layers and the horny layer display typical molluscum bodies. In this paper, we describe an unusual case of MC in a cystic...

journal_title：Journal of cutaneous pathology

authors： Aloi FG,Pippione M

更新日期：1985-04-01 00:00:00

abstract：:A survey of conditions with mucinous deposits is given. The most important factors for their diagnosis are to consider these disorders and to stain the slides for proteoglycans or glycosaminoglycans; the most common routine techniques are the Giemsa and the Alcian-blue stain. More sophisticated methods allow different...

journal_title：Journal of cutaneous pathology

authors： Steigleder GK,Küchmeister B

更新日期：1985-06-01 00:00:00

abstract：:Peristomal ulcer with cutaneous intestinal metaplasia, defined by scattered colonic crypts within variably intact epidermis, is an exceedingly rare pathologic diagnosis, which possesses the potential to progress to primary adenocarcinoma. Herein, we report the third case of cutaneous intestinal metaplasia in a peristo...

journal_title：Journal of cutaneous pathology

authors： Tinker DG,Roberts S,Hurley MY,Missall TA

更新日期：2020-05-01 00:00:00

abstract：:The usual method for detecting spirochetes in tissue sections is the silver stain; however, they are often difficult to detect due to marked background staining commonly seen with this technique. In certain clinical settings, such as neurosyphilis, congenital syphilis, and immunosuppressive conditions including human ...

journal_title：Journal of cutaneous pathology

authors： Hoang MP,High WA,Molberg KH

更新日期：2004-10-01 00:00:00

abstract：:The main histopathological features in the cutaneous lesions of Churg-Strauss syndrome (CSS) are dermal leukocytoclastic vasculitis with a variable eosinophilic infiltrate and non-vasculitic tissue eosinophilia with granuloma formation. This wide histopathological spectrum may account for the various skin manifestatio...

journal_title：Journal of cutaneous pathology

authors： Ishibashi M,Kudo S,Yamamoto K,Shimai N,Chen KR

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Long-term preservation of immunofluorescence is important for re-examinations. We investigated whether the storage of direct immunofluorescent (DIF)-positive slides at room temperature was reliable in daily practice. METHODS:One hundred and twenty-five DIF-positive slides from the skin of 52 patients were e...

journal_title：Journal of cutaneous pathology

authors： Dikicioglu E,Meteoglu I,Okyay P,Culhaci N,Kacar F

更新日期：2003-08-01 00:00:00

abstract：:A 78-year-old woman with a history of follicular carcinoma of the thyroid developed a painless nodule on her face. A skin biopsy showed a dermal tumor composed of cells with granular, eosinophilic cytoplasm. Immunoperoxidase staining demonstrated thyroglobulin in the tumor cells, confirming the diagnosis of metastatic...

journal_title：Journal of cutaneous pathology

authors： Rico MJ,Penneys NS

更新日期：1985-04-01 00:00:00

abstract：:Thirty cases of poorly differentiated carcinomas of the skin were examined for the expression of vimentin. All cases expressed cytokeratins; in addition, 12 cases were positive for vimentin. These were all non-reactive with antibodies to S100 protein, HMB45 and desmin. The finding of vimentin in poorly differentiated ...

journal_title：Journal of cutaneous pathology

authors： Iyer PV,Leong AS

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:The use of immunohistochemical (IHC) stains in dermatopathology is commonplace; however, little is known regarding utilization trends in melanoma diagnosis. Current Medicare local coverage determinations (LCDs) state that most pigmented lesions, including melanoma, can be diagnosed using H&E alone. METHODS:...

journal_title：Journal of cutaneous pathology

authors： Dinehart MS,Dinehart SM,Sukpraprut-Braaten S,High WA

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Cutaneous epithelioid angiosarcoma is a type of cutaneous angiosarcoma and usually arise both on the head or neck of the elderly. CASE REPORT:An 86-year-old male with an epithelioid angiosarcoma of the scalp that mimicked malignant melanoma. RESULTS:A large irregular dark grey-blue plaque with an adjacent ...

journal_title：Journal of cutaneous pathology

authors： Brightman LA,Demierre MF,Byers HR

更新日期：2006-01-01 00:00:00

abstract：:We examined the proliferative characteristics of 20 basal-cell carcinomas (BCCs) and 16 trichoepitheliomas (TEps) in an effort to understand and explore possible differences in their tumorigenic cell-cycle properties. These tumors were first compared for their expression of the nuclear proliferative protein Ki-67 and ...

journal_title：Journal of cutaneous pathology

authors： Lum CA,Binder SW

更新日期：2004-09-01 00:00:00

abstract：:Fifteen halo nevi were stained for the presence of S100 protein by an unlabelled antibody peroxidase-antiperoxidase method. S100 protein was clearly identifiable within nevus cell nests in the inflammatory infiltrate. The presence of this substance helped to identify nevus cells in dense inflammatory infiltrates and c...

journal_title：Journal of cutaneous pathology

authors： Penneys NS,Mayoral F,Barnhill R,Ziegels-Weissman J,Nadji M

更新日期：1985-02-01 00:00:00

abstract：:Adenomyoepithelioma is a rare, microscopically distinctive tumor of the skin. This article explores an example that presented in the inguinal area in a 29-year-old woman, mimicking adenopathy. Histopathologically, the tumor included two different areas: a cystic area consisting of tubules and glands in hyalinized stro...

journal_title：Journal of cutaneous pathology

authors： Sabater Marco V

更新日期：2012-07-01 00:00:00

abstract：:Cutaneous lesions of lupus erythematosus (LE) show a broad spectrum of clinicopathologic features. Histopathologically, besides typical patterns such as interface dermatitis, perivascular lymphocytic infiltrate and dermal mucin deposits, an involvement of the eccrine structures, especially the acrosyringium, may be ob...

journal_title：Journal of cutaneous pathology

authors： Fried I,Wiesner T,Cerroni L

更新日期：2010-01-01 00:00:00

abstract：:Extraskeletal Ewing's sarcoma has been recognized as being histologically indistinguishable from Ewing's sarcoma of bone. Although the occurrence of extraosseous Ewing's sarcoma in deep soft tissues has been well described, such cutaneous lesions are rare. We report the clinical history, histopathologic findings, and ...

journal_title：Journal of cutaneous pathology

authors： Peters MS,Reiman HM,Muller SA

更新日期：1985-12-01 00:00:00

abstract：BACKGROUND:Langerhans' cells (CD1a positive, bone marrow-derived cells), are the antigen presenting cells of the skin. Our knowledge about the status of these cells in eczematous dermatitis is incomplete. AIM:This study tests the hypothesis that 'the development of eczematous dermatitis is associated with alterations ...

journal_title：Journal of cutaneous pathology

authors： Hussein MR

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Studies on the precise cause of increased melanization in pigmented basal cell carcinomas (BCC) are limited. We aimed to determine whether the cause of melanization is from increased number of melanocytes or increased melanin pigment, and if there is a difference in the number of melanocytes on different sun...

journal_title：Journal of cutaneous pathology

authors： Brankov N,Prodanovic EM,Hurley MY

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Cutaneous mesothelioma is rare but may occur following local surgical procedures for visceral mesothelioma or as a metastasis. METHODS:A patient with pleural mesothelioma, who developed papules within chest wall scars, 14 and 15 months after pleural biopsy and thoracentesis, respectively, is reported. RESU...

journal_title：Journal of cutaneous pathology

authors： Shieh S,Grassi M,Schwarz JK,Cheney RT

更新日期：2004-08-01 00:00:00

abstract：:We report an unusual case occurring in a 25-year-old male of a balloon cell nevus which also showed clinical and pathological features of a halo nevus. ...

journal_title：Journal of cutaneous pathology

authors： Côté J,Watters AK,O'Brien EA

更新日期：1986-04-01 00:00:00

abstract：:We describe a patient with thrombocytopenia-absent radius (TAR) syndrome, multisystemic Langerhans cell histiocytosis and multiple reticulohistiocytomas. A mutational study by massive sequencing identified the Val600Glu (V600E) BRAF mutation in the Langerhans cell histiocytosis lesions, but no molecular alterations we...

journal_title：Journal of cutaneous pathology

authors： Hipólito LN,Mendoza-Cembranos MD,Villaescusa MT,Jo-Velasco M,Requena L,Alegría-Landa V

更新日期：2019-08-01 00:00:00

abstract：:Systemic sclerosis (SSc) is an autoimmune systemic disease characterized by small vessel involvement that leads to tissue ischemia and fibroblast stimulation resulting in accumulation of collagen (fibrosis) in the skin and internal organs. Lipomembranous panniculitis is a peculiar type of fat necrosis and has been rep...

journal_title：Journal of cutaneous pathology

authors： Almeida MS,Lima SC,Carvalho LL,Almeida JV,Santos LG,Rolim JR,Rocha TE

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:p16 immunostaining has been used to aid and improve the histopathologic evaluation of equivocal cervical lesions with associated low-grade or high-grade dysplasia. However, the utility of p16 immunostaining in the diagnosis of atypical genital skin lesions remains debatable. METHODS:We conducted a cross-sec...

journal_title：Journal of cutaneous pathology

authors： Ezaldein H,Lott JP,McNiff JM,Hui P,Buza N,Ko CJ

更新日期：2015-08-01 00:00:00

abstract：:Desmoplastic melanoma can be difficult to distinguish from desmoplastic melanocytic nevi both clinically and histopathologically. Several attempts have been made to explore the use of ancillary studies to facilitate this distinction. Prior work has suggested that immunohistochemical expression of p16 could help distin...

journal_title：Journal of cutaneous pathology

authors： Blokhin E,Pulitzer M,Busam KJ

更新日期：2013-09-01 00:00:00

abstract：:Lymphomatoid granulomatosis (LG) is a rare Epstein-Barr virus (EBV)-associated B-cell lymphoproliferative disorder presenting in middle adulthood that nearly always affects the lungs and shows cutaneous involvement in up to 50% of cases. Skin lesions are present at the time of diagnosis in roughly one-third of patient...

journal_title：Journal of cutaneous pathology

authors： Rysgaard CD,Stone MS

更新日期：2015-03-01 00:00:00