Delineation of nevus cell nests in inflammatory infiltrates by immunohistochemical staining for the presence of S100 protein.

abstract：BACKGROUND:The aim of this study was to evaluate the effectiveness of CD117 immunostaining for diagnosing cutaneous adnexal tumors, which has not been previously established. METHODS:CD117 immunostaining was performed on representative sections of 87 clinicopathologically confirmed cutaneous apocrine/eccrine tumors, 1...

journal_title：Journal of cutaneous pathology

authors： Goto K

更新日期：2015-07-01 00:00:00

abstract：:Disseminated bacillus Calmette-Guérin infection (BCGitis) is an uncommon condition which is usually associated with primary immunodeficiency. Skin histopathology findings have been described in rare cases only. A retrospective clinicopathological study was performed to assess the potential utility of skin biopsies in ...

journal_title：Journal of cutaneous pathology

authors： Gantzer A,Neven B,Picard C,Brousse N,Lortholary O,Fischer A,Bodemer C,Fraitag S

更新日期：2013-01-01 00:00:00

abstract：:The histological picture of molluscum contagiosum (MC) is well known: the epidermis grows down into the dermis as multiple, closely packed pear-shaped lobules. The epithelial cells of the outermost layers and the horny layer display typical molluscum bodies. In this paper, we describe an unusual case of MC in a cystic...

journal_title：Journal of cutaneous pathology

authors： Aloi FG,Pippione M

更新日期：1985-04-01 00:00:00

abstract：:Systemic sclerosis (SSc) is an autoimmune systemic disease characterized by small vessel involvement that leads to tissue ischemia and fibroblast stimulation resulting in accumulation of collagen (fibrosis) in the skin and internal organs. Lipomembranous panniculitis is a peculiar type of fat necrosis and has been rep...

journal_title：Journal of cutaneous pathology

authors： Almeida MS,Lima SC,Carvalho LL,Almeida JV,Santos LG,Rolim JR,Rocha TE

更新日期：2010-11-01 00:00:00

abstract：:The advent of immunoperoxidase technique on paraffin embedded tissue has identified a number of shared immunologic markers present in various lymphoproliferative cutaneous disorders. Two such disorders are the recently described primary cutaneous CD30-positive anaplastic large cell lymphoma (ALCL) and lymphomatoid pap...

journal_title：Journal of cutaneous pathology

authors： Tomaszewski MM,Lupton GP,Krishnan J,May DL

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:Trichilemmal (pilar) cysts are common skin lesions that usually occur on the scalp of elderly women. They differentiate towards the follicular outer root sheath epithelium and show trichilemmal keratinization. Proliferating trichilemmal tumor (PTT) shows features of typical pilar cyst, but additionally shows...

journal_title：Journal of cutaneous pathology

authors： Folpe AL,Reisenauer AK,Mentzel T,Rütten A,Solomon AR

更新日期：2003-09-01 00:00:00

abstract：:Cutaneous syncytial myoepithelioma is a recently described rare tumor of the dermis. It is derived and composed purely of myoepithelial cells and shows a characteristic syncytial growth pattern of neoplastic cells with little intervening stroma and no recognizable ductal structures. It represents a diagnostic challeng...

journal_title：Journal of cutaneous pathology

authors： Alomari AK,Brown N,Andea AA,Betz BL,Patel RM

更新日期：2017-10-01 00:00:00

abstract：:Biologic therapies targeting tumor necrosis factor (TNF)-alpha have become a mainstay in the management of a number of autoimmune diseases. We report a series of adverse skin eruptions in six patients (four females, two males, age: 21-58 years, mean: 39) receiving 4 months to 10 years (mean 3.1 years) of anti-TNF-alph...

journal_title：Journal of cutaneous pathology

authors： Hawryluk EB,Linskey KR,Duncan LM,Nazarian RM

更新日期：2012-05-01 00:00:00

abstract：:The non-specific clinical findings and variable histopathological features of cutaneous tuberculosis and non-tuberculous mycobacterial infections often make it difficult to establish a diagnosis and initiate appropriate therapy. We investigated 25 patients diagnosed with mycobacterial infections of the skin in Hanyang...

journal_title：Journal of cutaneous pathology

authors： Min KW,Ko JY,Park CK

更新日期：2012-06-01 00:00:00

abstract：:A patient with chronic myelocytic leukemia (CML) in blast transformation with extensive involvement of the skin is reported. The leukemic infiltrates consisted of blasts with lymphoblastoid morphology which were positive for terminal deoxynucleotidyl transferase (TdT) by fluorescent assay. The infiltrates rapidly reso...

journal_title：Journal of cutaneous pathology

authors： Ansell JE,Bhawan J,Pechet L

更新日期：1980-10-01 00:00:00

abstract：BACKGROUND:Angiosarcomas arise in the scalp and face in the elderly, in association with chronic lymphedema (Stewart-Treves syndrome), and in irradiated areas. Rarely in these settings, angiosarcomas exhibit pure spindle cell phenotype. METHODS:Herein, the clinicopathologic features of a 72-year-old-woman with spindle...

journal_title：Journal of cutaneous pathology

authors： Kiyohara T,Kumakiri M,Kobayashl H,Itoh K,Lao LM,Ohkawara A,Nakmura H

更新日期：2002-02-01 00:00:00

abstract：:A 57-year-old woman with cutaneous mastocytosis of 23 years duration developed a hyperpigmented abdominal plaque composed of confluent indurated papules that enlarged for a period of 1 year to 12 x 8 cm. Biopsy showed dermal infiltration by closely packed spindle-shaped mast cells, fibroblasts, collagen, and scattered...

journal_title：Journal of cutaneous pathology

authors： Wood C,Sina B,Webster CG,Kurgansky D,Drachenberg CB,Reedy EA

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:Follicular mycosis fungoides is an unusual variant of mycosis fungoides (MF). Unlike classic MF where atypical lymphocytes show a predilection for the epidermis (epidermotropism), follicular MF displays a malignant lymphocytic infiltrate tropic for hair follicles (folliculotropism). This malignant lymphocyti...

journal_title：Journal of cutaneous pathology

authors： DeBloom J 2nd,Severson J,Gaspari A,Scott G

更新日期：2001-07-01 00:00:00

abstract：:Large cell neuroendocrine carcinoma (LCNEC) of the larynx is an aggressive form of neuroendocrine carcinoma that affects smokers at an average age of 60 years. LCNEC is characterized by large cells with round to ovoid nuclei distributed in a trabecular or nested growth pattern. Previously, laryngeal LCNEC and atypical...

journal_title：Journal of cutaneous pathology

authors： Dunn A,Broadfoot BG,Hunt J,Kaley JR,Atiq O,Gutta NB,Wang X,Gardner JM,Shalin SC

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Hereditary hypotrichosis simplex (MIM 146520, HHS) is a rare form of nonsyndromic alopecia. The locus for autosomal dominant HHS was mapped to 18p11.32-p11.23 and 6p21.3, respectively, suggestive of genetic heterogeneity. AIM:To identify the disease-causing gene for a four-generation Chinese family with dom...

journal_title：Journal of cutaneous pathology

authors： Xu C,Zhang L,Chen N,Su B,Pan CM,Li JY,Zhang GW,Liu Z,Sheng Y,Song HD

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Direct immunofluorescence (DIF) is a valuable tool in the diagnosis of cutaneous lupus erythematosus (LE). Our goal was to characterize the most frequent immune reactants in the skin biopsies of cutaneous LE and identify the most common immunofluorescence staining patterns. METHODS:DIF results of immunoglob...

journal_title：Journal of cutaneous pathology

authors： Kontos AP,Jirsari M,Jacobsen G,Fivenson DP

更新日期：2005-05-01 00:00:00

abstract：:Post-vaccinial non-viral folliculitis has been recognized in the past decade as a new adverse cutaneous reaction to smallpox vaccination. Contrary to more serious smallpox vaccine reactions, post-vaccinial non-viral folliculitis has a benign course and resolves spontaneously within approximately 7 days. We describe ad...

journal_title：Journal of cutaneous pathology

authors： Bunick CG,Mariwalla K,Ibrahim O,Modi B,Imaeda S,McNiff JM

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Benign lichenoid keratosis (BLK) is a well-known clinicopathologic entity and several histopathologic patterns have been described. Features mimicking mycosis fungoides (MF) in clinically typical BLKs have not yet been emphasized. The aim of this study was to confirm the occurrence of an MF-like pattern of B...

journal_title：Journal of cutaneous pathology

authors： Al-Hoqail IA,Crawford RI

更新日期：2002-05-01 00:00:00

abstract：:A case is presented of white plaques occurring predominantly on the vulvar mucosa of a 28-year-old female diagnosed as white sponge nevus (WSN). WSN is a rare, autosomal dominant disorder involving mucous membranes. It predominantly affects the oral mucosa; however, it has been reported to rarely involve extraoral muc...

journal_title：Journal of cutaneous pathology

authors： Cutlan JE,Saunders N,Olsen SH,Fullen DR

更新日期：2010-03-01 00:00:00

abstract：:The characteristic histologic change seen at 2 h in the Rumpel-Leede (Hess) test is, in addition to focal hemorrhage in the upper dermis, a perivascular lymphocyte infiltrate with focal areas of lymphocytic epidermal invasion. The histologic findings, even with the liquefaction degeneration, are similar to those of pu...

journal_title：Journal of cutaneous pathology

authors： Duncan SC,Winkelmann RK

更新日期：1979-02-01 00:00:00

abstract：:Traditionally, the pigmented purpuric eruptions (PPE) have been subdivided into four histologic categories, based upon variations in histologic pattern and clinical morphologies. In recent years, it has become apparent that the lesions behave similarly, and this family of eruptions has become grouped under the term PP...

journal_title：Journal of cutaneous pathology

authors： Smoller BR,Kamel OW

更新日期：1991-12-01 00:00:00

abstract：:Immunotherapies targeting cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) and the programmed cell death 1 (PD-1) receptor and its ligand (PD-L1) have showed significant therapeutic benefit in patients with clinically advanced solid malignancies, including melanoma. However, immune-related adverse events (irAE) ar...

journal_title：Journal of cutaneous pathology

authors： Trinidad C,Nelson KC,Glitza Oliva IC,Torres-Cabala CA,Nagarajan P,Tetzlaff MT,Ivan D,Hwu WJ,Prieto VG,Curry JL,Aung PP

更新日期：2018-07-01 00:00:00

abstract：:We report a 2-year-old girl with developmental delay who, from the age of 1 year, developed perniotic lesions of the hands and feet initially diagnosed as chilblain lupus. Histological examination showed features of epidermal necrosis with intraepidermal bulla formation, interface dermatitis, lymphocytic vasculitis wi...

journal_title：Journal of cutaneous pathology

authors： Kolivras A,Aeby A,Crow YJ,Rice GI,Sass U,André J

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:The present study evaluates the signal transducer and activator of transcription-3 (STAT-3) expression and activation in actinic cheilitis (AC) and the relationship of this protein with the degree of epithelial dysplasia. METHODS:Twenty-five cases of AC were analyzed. Normal lip mucosa was used as a control...

journal_title：Journal of cutaneous pathology

authors： Cury PR,Furuse C,de Araújo NS,de Araújo VC

更新日期：2007-08-01 00:00:00

abstract：:Histologic, immunologic and electron microscopic studies were performed in a patient with transient acantholytic dermatosis which involved oral mucosa. Hitologic and electron microscopic findings were almost identical in both cutaneous and mucous membrane lesions, and these were similar to pemphigus vulgaris; suprabas...

journal_title：Journal of cutaneous pathology

authors： Kanzaki T,Hashimoto K

更新日期：1978-02-01 00:00:00

abstract：:Steatocystoma multiplex is characterized by the development of numerous steatocystomas. The condition has occasionally been related to congenital bilateral preauricular sinuses. Herein, we present the third case of such an association, a 34-year-old male who was born with bilateral preauricular sinuses that were surgi...

journal_title：Journal of cutaneous pathology

authors： Fernandez-Flores A,Cuesta CC,García CS,del Río JS

更新日期：2014-08-01 00:00:00

abstract：:Chronic lymphocytic leukaemia (CLL) shows cutaneous involvement in 2% of cases. Merkel cell carcinoma (MCC) is a rare primary cutaneous epithelial neoplasm most commonly found in sun-exposed sites in elderly male Caucasians. A 66-year-old man presented with a 2-month history of a purple painless 2 cm tumor on the scal...

journal_title：Journal of cutaneous pathology

authors： Craig PJ,Calonje JE,Harries M,Stefanato CM

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Melanocytic nevi from the genitalia are uncommon. Nevi on the vulva are much better described than nevi on male genitalia. To our knowledge, a systematic study of preputial melanocytic nevi has not been reported. OBJECTIVE:To investigate the frequency of clinically unapparent melanocytic nevi on a series of...

journal_title：Journal of cutaneous pathology

authors： Val-Bernal JF,Val D,Garijo MF

更新日期：2009-04-01 00:00:00

abstract：:We present a challenging case of chronic, erosive, scarring dermatosis of the vulva with clinical features of long standing lichen sclerosus (LS), namely pallor and loss of vulval architecture, but with histopathology consistently showing features of an acantholytic process. The history and clinical features of this c...

journal_title：Journal of cutaneous pathology

authors： Haddadeen C,Theaker J,Rowen D,Lotery H

更新日期：2020-01-01 00:00:00

abstract：:Goltz syndrome (focal dermal hypoplasia) is an X-linked dominant disorder that is classically associated with yellowish papules representing fat herniation (superficial adipocytes). We report a series of three cases, with clinicopathologic correlation of biopsies from Blaschkoid streaks. A range of histopathologic fea...

journal_title：Journal of cutaneous pathology

authors： Ko CJ,Antaya RJ,Zubek A,Craiglow B,Damsky W,Galan A,McNiff JM

更新日期：2016-05-01 00:00:00