A comparison of clinical, morphological and immunohistochemical features of lymphomatoid papulosis and primary cutaneous CD30(Ki-1)-positive anaplastic large cell lymphoma.

Abstract:

:The advent of immunoperoxidase technique on paraffin embedded tissue has identified a number of shared immunologic markers present in various lymphoproliferative cutaneous disorders. Two such disorders are the recently described primary cutaneous CD30-positive anaplastic large cell lymphoma (ALCL) and lymphomatoid papulosis; both entities are characterized by CD30-positive large atypical cells predominantly of T cell origin. We have compared the clinical, morphological and immunohistochemical features of 50 patients with lymphomatoid papulosis to a group of 27 patients with cutaneous CD30-positive ALCL. There are clear differences between the clinical presentation in these two diseases, and although both are characterized by similar atypical cells, the histologic pattern and distribution of atypical cells is sufficiently different to allow distinction and specific diagnosis based on hematoxylin and eosin stained sections supported by the immunohistochemical stains. In addition, both diseases are characterized by a long benign course, rarely complicated by development of lymphoreticular malignancy and invariably demonstrate CD30 (Ki-1) antigen positive large atypical cells.

journal_name

J Cutan Pathol

authors

Tomaszewski MM,Lupton GP,Krishnan J,May DL

doi

10.1111/j.1600-0560.1995.tb01413.x

subject

Has Abstract

pub_date

1995-08-01 00:00:00

pages

310-8

issue

4

eissn

0303-6987

issn

1600-0560

journal_volume

22

pub_type

杂志文章
  • Broad histopathologic patterns of non-glabrous skin and glabrous skin from patients with a new variant of endemic pemphigus foliaceus-part 1.

    abstract::A prospective, controlled epidemiologic survey performed in El Bagre, Colombia revealed a new variant of endemic pemphigus disease, occurring in a gold mining region. The disease resembled Senear-Usher syndrome, and occurred in an endemic fashion. The aim of this study is to describe the most frequent histopathologic ...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.1600-0560.2009.01315.x

    authors: Howard MS,Yepes MM,Maldonado-Estrada JG,Villa-Robles E,Jaramillo A,Botero JH,Patiño PJ,Hashimoto T,Abreu-Velez AM

    更新日期:2010-02-01 00:00:00

  • Ossifying fibromyxoid tumor of soft parts of the back.

    abstract::We report a first case of ossifying fibromyxoid tumor of soft parts of the back, a 10 x 9.5 x 6 cm well-circumscribed elevated subcutaneous tumor demarcated by an incomplete fibrous capsule with bone formation at its base. The tumor was composed of both myxomatous areas with spindle tumor cells and pseudoalveolar stru...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.1600-0560.1996.tb01316.x

    authors: Nakayama F,Kuwahara T

    更新日期:1996-08-01 00:00:00

  • Severe cutaneous bacillus Calmette-Guérin infection in immunocompromised children: the relevance of skin biopsy.

    abstract::Disseminated bacillus Calmette-Guérin infection (BCGitis) is an uncommon condition which is usually associated with primary immunodeficiency. Skin histopathology findings have been described in rare cases only. A retrospective clinicopathological study was performed to assess the potential utility of skin biopsies in ...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/cup.12048

    authors: Gantzer A,Neven B,Picard C,Brousse N,Lortholary O,Fischer A,Bodemer C,Fraitag S

    更新日期:2013-01-01 00:00:00

  • Histiocyte-rich pleomorphic mastocytoma: an uncommon variant mimicking juvenile xanthogranuloma and Langerhans cell histiocytosis.

    abstract::An 11-year old Caucasian female with a remote history of urticaria pigmentosa presented with a neck mass. A biopsy demonstrated a large intradermal nodule composed of unusually large epithelioid mast cells, including a prominent subset with bi-lobed and multi-lobed nuclei. By immunohistochemistry, the cells expressed ...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.1600-0560.2009.01257.x

    authors: Tran DT,Jokinen CH,Argenyi ZB

    更新日期:2009-11-01 00:00:00

  • Diffuse cutaneous bullous mastocytosis with IgM deposits at dermo-epidermal junction.

    abstract::Cutaneous mastocytosis is a disease characterized by the infiltration and proliferation of mast cells in the skin. In children, the most common form of presentation is urticaria pigmentosa, while the diffuse cutaneous bullous mastocytosis is one of the rarest subtypes seen. The aim of this paper is to present a case o...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/cup.12635

    authors: Slavescu KC,Chiorean R,Danescu S,Bota M,Rogojan L,Baican A

    更新日期:2016-03-01 00:00:00

  • Human papillomavirus-negative ileostomal chronic papillomatous dermatitis.

    abstract:BACKGROUND:Papillomatous stoma-related skin lesions may result from irritant reactions or infection with epidermodysplasia verruciformis human papillomavirus (HPV) types. METHODS:We report upon a papillomatous lesion at the ileostoma of a 63-year-old male with familial adenomatous polyposis and colorectal adenocarcino...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1046/j.0303-6987.2003.048.x

    authors: Williams CM,Wieland U,Rodning CB,Horenstein MG

    更新日期:2003-04-01 00:00:00

  • Polymorphous sweat gland carcinoma: a report of two cases.

    abstract::Polymorphous sweat gland carcinoma (PSGC) is a rare adnexal neoplasm with characteristic variegated histopathologic findings and low-grade clinical behavior. First described in 1994, only 11 cases have been reported in the literature. It is named for the multiplicity of architectural patterns that may be present: soli...

    journal_title:Journal of cutaneous pathology

    pub_type:

    doi:10.1111/cup.12695

    authors: Walker A,Mesinkovska NA,Emanuel PO,Vidimos A,Billings SD

    更新日期:2016-07-01 00:00:00

  • Poorly differentiated squamous cell carcinomas of the skin can express vimentin.

    abstract::Thirty cases of poorly differentiated carcinomas of the skin were examined for the expression of vimentin. All cases expressed cytokeratins; in addition, 12 cases were positive for vimentin. These were all non-reactive with antibodies to S100 protein, HMB45 and desmin. The finding of vimentin in poorly differentiated ...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.1600-0560.1992.tb01556.x

    authors: Iyer PV,Leong AS

    更新日期:1992-02-01 00:00:00

  • A case of multinucleate cell angiohistiocytoma in a 14-year-old boy showing two different clinical and histopathological findings.

    abstract::Multinucleate cell angiohistiocytoma (MCAH) is a rare cutaneous disease entity characterized by multiple red-to-brown or violaceous papules usually located on the acral regions, such as the face and the distal arms and legs. It affects elderly women more than men and rarely occurs at a young age. The exact pathogenic ...

    journal_title:Journal of cutaneous pathology

    pub_type:

    doi:10.1111/cup.13398

    authors: Suh JH,Lee SK,Kim HY,Kim MS,Lee UH

    更新日期:2019-03-01 00:00:00

  • Matrical carcinoma of the skin.

    abstract::Two elderly patients with unusual hair-follicle tumors of the face are reported. The lesions showed some histologic resemblance to pilomatrixomas but differed by the presence at the advancing edge of cytologically-atypical cells without the usual shadow cell transformation and maturation of pilomatrixomas. The term ma...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.1600-0560.1980.tb00975.x

    authors: Weedon D,Bell J,Mayze J

    更新日期:1980-02-01 00:00:00

  • Multiple perifollicular fibromas: report of a case and analysis of the literature.

    abstract::Perifollicular fibroma is a cutaneous hamartomatous proliferation of the pilar connective tissue sheath. We describe a patient with multiple perifollicular fibromas and analyze the literature on this topic. Histologically, perifollicular fibroma is characterized by a concentric arrangement of collagen fibers surroundi...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0560.1994.tb00291.x

    authors: Junkins-Hopkins JM,Cooper PH

    更新日期:1994-10-01 00:00:00

  • Scattered atypical melanocytes with hyperchromatic nuclei in the nail matrix: diagnostic clue for early subungual melanoma in situ.

    abstract:BACKGROUND:The lack of highly specific clinical and histopathological criteria has contributed to the delay in diagnosis of subungual melanoma in situ in its early stages. METHODS:Eighteen cases of subungual melanoma in situ, the largest series reported to date, were analyzed to characterize the clinical and histopath...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/cup.12634

    authors: Park SW,Jang KT,Lee JH,Park JH,Kwon GY,Mun GH,Lee DY,Lee JB,Park KK

    更新日期:2016-01-01 00:00:00

  • C3d immunohistochemistry on formalin-fixed tissue is a valuable tool in the diagnosis of bullous pemphigoid of the skin.

    abstract:BACKGROUND:Direct immunofluorescence (DIF) testing is an important procedure in the diagnosis of autoimmune bullous dermatoses. We investigated the expression of C3d in formalin-fixed, paraffin-embedded tissue of autoimmune bullous dermatoses. METHODS:The immunohistochemical expression of C3d in bullous pemphigoid (BP...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.1600-0560.2009.01450.x

    authors: Pfaltz K,Mertz K,Rose C,Scheidegger P,Pfaltz M,Kempf W

    更新日期:2010-06-01 00:00:00

  • Unusual subcutaneous dedifferentiated liposarcoma exhibiting coexistence of meningothelial-like whorls and inflammatory myofibroblastic tumor-like structures.

    abstract::To explore the clinicopathological features of a rare dedifferentiated liposarcoma (DDLPS) with meningothelial-like whorls, we retrospectively analyzed 46 reported cases and 1 case that we encountered. Fluorescence in situ hybridization (FISH) analysis of the MDM2 amplification status of our case was also performed. O...

    journal_title:Journal of cutaneous pathology

    pub_type:

    doi:10.1111/cup.13621

    authors: Chen S,He S,Huang H,Li L,Wang W,Cui Z,Zhang R

    更新日期:2020-02-01 00:00:00

  • Transepithelial elimination in sarcoidosis: a frequent finding.

    abstract:BACKGROUND:Transepithelial elimination is a process by which dermal materials are expelled through an active epithelial-dermal connective tissue interaction. It has been described as a regular or sporadic occurrence in a variety of dermatologic conditions, including sarcoidosis. OBSERVATION:Our patient demonstrated a ...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/cup.12253

    authors: Ismail A,Beckum K,McKay K

    更新日期:2014-01-01 00:00:00

  • Infection by Borrelia burgdorferi and cutaneous B-cell lymphoma.

    abstract::In past years, association of primary cutaneous B-cell lymphoma (CBCL) with infection by Borrelia burgdorferi has been reported in a few patients. The evidence for a pathogenetic role was based on clinical grounds or raised titre of antibodies in serum. Both methods, however, do not prove the association between the m...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.1600-0560.1997.tb01318.x

    authors: Cerroni L,Zöchling N,Pütz B,Kerl H

    更新日期:1997-09-01 00:00:00

  • EWSR1-PBX3 gene fusion in cutaneous syncytial myoepithelioma.

    abstract::Cutaneous syncytial myoepithelioma (CSM) is a recently recognized, histopathological variant of myoepithelial (ME) tumors of the skin. It is characterized by a syncytial arrangement of spindled, ovoid, and/or epithelioid cells forming a well-circumscribed, unencapsulated dermal nodule. There is a paucity of intervenin...

    journal_title:Journal of cutaneous pathology

    pub_type:

    doi:10.1111/cup.13450

    authors: MacKinnon WF,Carter MD,Bridge JA,Tremaine RD,Walsh NMG

    更新日期:2019-06-01 00:00:00

  • Histological spectrum of cutaneous reactions to aspirin in chronic idiopathic urticaria.

    abstract:BACKGROUND:During a clinical trial, we obtained 16 biopsies of skin eruptions induced by aspirin in patients with chronic idiopathic urticaria (CIU). In this setting, aspirin triggers skin eruptions through a well-established non-immunological mechanism involving the inhibition of cyclooxygenase type I. This presented ...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.0303-6987.2004.0195.x

    authors: Zembowicz A,Mastalerz L,Setkowicz M,Radziszewski W,Szczeklik A

    更新日期:2004-04-01 00:00:00

  • Angiosarcomatous transdifferentiation of metastatic melanoma.

    abstract::Melanoma is known to show considerable variation in its histopathological presentation. In exceptional cases, heterologous or divergent differentiation (metaplastic melanoma) can be observed. We report a case of a 69-year-old man who was diagnosed with nodular melanoma on the right upper leg. One year later, the patie...

    journal_title:Journal of cutaneous pathology

    pub_type:

    doi:10.1111/cup.13857

    authors: Kilsdonk MJ,Romeijn TR,Kelder W,van Kempen LC,Diercks GF

    更新日期:2020-12-01 00:00:00

  • Fli-1 expression in mycosis fungoides.

    abstract:BACKGROUND:The Fli-1 transcription factor functions in cellular proliferation and tumorigenesis. Its role in various neoplasms and its presence in lymphocytes suggest a link between Fli-1 dysregulation and the pathogenesis of mycosis fungoides (MF). In this study, we further elucidate this possible link. METHODS:Secti...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.1600-0560.2006.00535.x

    authors: Quick CM,Smoller BR,Hiatt KM

    更新日期:2006-09-01 00:00:00

  • Value of p63 and podoplanin (D2-40) immunoreactivity in the distinction between primary cutaneous tumors and adenocarcinomas metastatic to the skin: a clinicopathologic and immunohistochemical study of 79 cases.

    abstract::The distinction of metastatic carcinomas to the skin from poorly differentiated primary cutaneous carcinomas and sometimes primary benign adnexal tumors can pose a significant diagnostic challenge. The purpose of this study was to evaluate the role of p63 and podoplanin (D2-40) immunoreactivity for separating primary ...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.1600-0560.2010.01517.x

    authors: Plaza JA,Ortega PF,Stockman DL,Suster S

    更新日期:2010-04-01 00:00:00

  • Co-existent cutaneous cryptococcosis of the forearm and cutaneous alternariosis of the leg in patient with metastatic thymoma.

    abstract:BACKGROUND:Cryptococcosis and alternariosis are rare opportunistic infections often observed in immunocompromised patients. Because Cryptococcus and Alternaria are ubiquitous fungi found in soil, the presence of fungi in the dermis has to be observed on histological examination to confirm a real cutaneous, invasive, in...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1046/j.0303-6987.2001.00035.x

    authors: Courville P,Favennec L,Viacroze C,Barrel A,Young P,Abboud P,Thomine E,Metayer J,Nouvet G

    更新日期:2002-01-01 00:00:00

  • C4d immunohistochemical stain of formalin-fixed paraffin-embedded tissue as a sensitive method in the diagnosis of bullous pemphigoid.

    abstract:BACKGROUND:Bullous pemphigoid (BP) is the most common type of subepidermal bullous disease. Direct immunofluorescence (DIF) is the gold standard for diagnosis, but it requires a fresh tissue specimen. This study was conducted to evaluate the accuracy of using immunohistochemical (IHC) analysis for the detection of C4d ...

    journal_title:Journal of cutaneous pathology

    pub_type: 临床试验,杂志文章

    doi:10.1111/cup.13490

    authors: Kamyab K,Abdolreza M,Ghanadan A,Mortazavi H,Nikoo A,Motavalli F,Nasimi M

    更新日期:2019-10-01 00:00:00

  • Type-I cryoglobulinemia-like histopathologic changes in tick bites: a useful clue for tissue diagnosis in the absence of tick parts.

    abstract:BACKGROUND:The histopathologic findings of localized reactions to tick bites may present as diagnostic dilemmas, especially if there is no history of a tick bite, or if the tick's mouthparts are not present in the biopsied skin. OBJECTIVE:Skin biopsies of patients with a clinical history of a tick bite were selected a...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1034/j.1600-0560.2001.290207.x

    authors: Stefanato CM,Phelps RG,Goldberg LJ,Perry AE,Bhawan J

    更新日期:2002-02-01 00:00:00

  • Expanding the clinicopathologic spectrum of palisaded encapsulated neuroma.

    abstract::Palisaded encapsulated neuroma (PEN; solitary circumscribed neuroma) is a benign, morphologically characteristic cutaneous or mucosal neuroma. Most are solitary lesions on the face, neck or oral mucosa. Histologically, the majority appears as dermal nodules of Schwann cell-rich fascicles, with or without distinctive e...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.1600-0560.2009.01380.x

    authors: Jokinen CH,Ragsdale BD,Argenyi ZB

    更新日期:2010-01-01 00:00:00

  • Subcutaneous juvenile xanthogranuloma.

    abstract::A 1-month-old female infant was seen in consultation because of a congenital subcutaneous nodule, 2 x 3 cm in diameter, in the right retroauricular area. The nodule was surgically excised. Histologically, a large subcutaneous nodular mass was well delimited but not encapsulated. It consisted of a monomorphous sheet of...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章,评审

    doi:10.1111/j.1600-0560.1995.tb00763.x

    authors: Sánchez Yus E,Requena L,Villegas C,Valle P

    更新日期:1995-10-01 00:00:00

  • Mucocutaneous pigmented macule as a result of zinc deposition.

    abstract:BACKGROUND:Mucocutaneous depositions of various metals such as silver, lead, gold, arsenic, mercury, iron, and bismuth have been previously published. Heavy metal deposition typically occurs in the setting of either prolonged topical application to intact skin, topical application to eroded or ulcerated skin, as a resu...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1034/j.1600-0560.2002.291008.x

    authors: Greenberg JE,Lynn M,Kirsner RS,Elgart GW,Hanly AJ

    更新日期:2002-11-01 00:00:00

  • Histopathological and immunohistochemical features of nodular podoconiosis.

    abstract:BACKGROUND:Podoconiosis is a familial geochemical dermatosis which is common in Ethiopia but relatively unknown in Europe/United States. It is related to exposure of bare feet to volcanic soil and presents with extensive bilateral lymphedema of legs and feet. Histopathological and immunohistochemical features of it hav...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/cup.12441

    authors: Wendemagegn E,Tirumalae R,Böer-Auer A

    更新日期:2015-03-01 00:00:00

  • Scanning electron microscopy of yeasts in seborrheic keratoses.

    abstract::Lesions of seborrheic keratoses were studied by scanning electrom microscopy. Numerous yeasts were present on the karatinized cells and hairs associated with the lesions. Surfaces of some yeasts were smooth and others were ruffled. The ruffles suggested the presence of a glycocalyx. The yeasts exhibited the morphologi...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.1600-0560.1980.tb00971.x

    authors: Wilborn WH,Montes LF

    更新日期:1980-02-01 00:00:00

  • Cutaneous composite hemangioendothelioma with satellitosis and lymph node metastases.

    abstract::The term hemangioendothelioma has been used in recent years to name a heterogeneous group of vascular neoplasms, intermediate in both biological behavior and histopathologic appearance between benign tumors (hemangiomas) and frankly malignant tumors (angiosarcomas). Thus, within the spectrum of hemangioendothelioma ha...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.1600-0560.2007.00781.x

    authors: Requena L,Luis Díaz J,Manzarbeitia F,Carrillo R,Fernández-Herrera J,Kutzner H

    更新日期:2008-02-01 00:00:00