Expanding the histologic findings in smallpox-related post-vaccinial non-viral folliculitis.

abstract：BACKGROUND:Tumor-infiltrating lymphocytes (TILs) are considered to play an important role in the antitumoral immune response. The presence and percentage of CD8-positive tumor-infiltrating T cells have been shown to correlate with differentiation and prognosis in various neoplasms. The aim of this study was to determin...

journal_title：Journal of cutaneous pathology

authors： Kamarashev J,Schaerer L,Burg G,Schmid MH,Müller B,Kempf W

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:p16 immunostaining has been used to aid and improve the histopathologic evaluation of equivocal cervical lesions with associated low-grade or high-grade dysplasia. However, the utility of p16 immunostaining in the diagnosis of atypical genital skin lesions remains debatable. METHODS:We conducted a cross-sec...

journal_title：Journal of cutaneous pathology

authors： Ezaldein H,Lott JP,McNiff JM,Hui P,Buza N,Ko CJ

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Despite its occasional unavailability, alcian blue has long been the stain of choice for the pathognomonic mucin-secreting cells of extramammary Paget's disease. Zirconyl hematoxylin is a recently developed substitute for alcian blue, which is made from common laboratory materials. METHODS:We have stained s...

journal_title：Journal of cutaneous pathology

authors： Smith AA,Silver TM

更新日期：2003-07-01 00:00:00

abstract：:Adenomyoepithelioma is a rare, microscopically distinctive tumor of the skin. This article explores an example that presented in the inguinal area in a 29-year-old woman, mimicking adenopathy. Histopathologically, the tumor included two different areas: a cystic area consisting of tubules and glands in hyalinized stro...

journal_title：Journal of cutaneous pathology

authors： Sabater Marco V

更新日期：2012-07-01 00:00:00

abstract：:Discrete junctional cellular aggregates ("nests"), partially staining with melanocytic markers, are described in lichenoid tissue reaction, mainly from chronically sun-exposed skin. The concomitant epidermal flattening and papillary dermal fibrosis with melanophages, may raise the differential diagnosis to that of a r...

journal_title：Journal of cutaneous pathology

authors： Ferrara G,Bradamante M,Broglia I,Petrillo G,Stefanato CM

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Recently, an intriguing concept was introduced into the literature that defines the area underlying the nail bed as a specific mesenchymal substructure unique to the nail organ. It has been termed onychodermis. The onychodermis expresses CD10 with remarkable specificity. Herein, we compare adult and fetal hu...

journal_title：Journal of cutaneous pathology

authors： Sellheyer K,Nelson P

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:The early stages of follicular mycosis fungoides (FMF) have not been described previously in the literature. OBJECTIVE:Our goal was to better categorize the clinicopathologic features of early stages of FMF. METHODS:The clinical notes of patients with a diagnosis of FMF seen during the previous 5 years wer...

journal_title：Journal of cutaneous pathology

authors： Tomasini C,Kempf W,Novelli M,Fava P,Annessi G,Rongioletti F,Fierro MT,Quaglino P

更新日期：2015-03-01 00:00:00

abstract：:Extravasation of doxorubicin in skin and soft tissue causes necrosis and ulceration. These ulcers form slowly and heal with great difficulty. The cause of ulceration is not known. Histologic changes in two patients suggest that an exaggeration of interface dermatitis like epidermal changes may be responsible for epide...

journal_title：Journal of cutaneous pathology

authors： Bhawan J,Petry J,Rybak ME

更新日期：1989-06-01 00:00:00

abstract：:Two cases of fibrous papule of the nose (FPN) with granular cell features are presented and discussed. Both lesions have classic architectural features of FPN; however, the main stromal cells show large cytoplasmic granules of the type seen in granular cells. We are uncertain of the significance of these findings. Our...

journal_title：Journal of cutaneous pathology

authors： Guitart J,Bergfeld WF,Tuthill RJ

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Direct immunofluorescence (DIF) is a valuable tool in the diagnosis of cutaneous lupus erythematosus (LE). Our goal was to characterize the most frequent immune reactants in the skin biopsies of cutaneous LE and identify the most common immunofluorescence staining patterns. METHODS:DIF results of immunoglob...

journal_title：Journal of cutaneous pathology

authors： Kontos AP,Jirsari M,Jacobsen G,Fivenson DP

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Histopathologic examination is sometimes inadequate for accurate and reproducible diagnosis of certain melanocytic neoplasms. As a result, more sophisticated and objective methods have been sought. The goal of this study was to identify a gene expression signature that reliably differentiated benign and mali...

journal_title：Journal of cutaneous pathology

authors： Clarke LE,Warf MB,Flake DD 2nd,Hartman AR,Tahan S,Shea CR,Gerami P,Messina J,Florell SR,Wenstrup RJ,Rushton K,Roundy KM,Rock C,Roa B,Kolquist KA,Gutin A,Billings S,Leachman S

更新日期：2015-04-01 00:00:00

abstract：:Three selected cases of transient acantholytic dermatosis were studied because of their definitive correlation with sweating due to fever and/ or bed-ridden situations. Biopsy specimens were serially sectioned and acantholysis was found in the acrosyringium or traced to connect to the acrosyringium in all biopsy speci...

journal_title：Journal of cutaneous pathology

authors： Hashimoto K,Moiin A,Chang MW,Tada J

更新日期：1996-04-01 00:00:00

abstract：:We present a challenging case of chronic, erosive, scarring dermatosis of the vulva with clinical features of long standing lichen sclerosus (LS), namely pallor and loss of vulval architecture, but with histopathology consistently showing features of an acantholytic process. The history and clinical features of this c...

journal_title：Journal of cutaneous pathology

authors： Haddadeen C,Theaker J,Rowen D,Lotery H

更新日期：2020-01-01 00:00:00

abstract：:Recently, T-cell lymphoma localized to the subcutaneous tissue has been reported. We report the clinical, histologic, immunohistochemical, and molecular genetic findings in 6 patients who we believe had this peculiar T-cell lymphoma with its unique morphologic and clinical features. All patients presented with deep-se...

journal_title：Journal of cutaneous pathology

authors： Mehregan DA,Su WP,Kurtin PJ

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:Ornithine decarboxylase (ODC) plays an important role in the biosynthesis of polyamines. Induction of ODC and polyamine synthesis has been demonstrated in neoplastic tumors and is thought to be related to the degree of malignancy. METHODS:In this study, we investigated a series of basal cell epitheliomas (B...

journal_title：Journal of cutaneous pathology

authors： Kagoura M,Toyoda M,Matsui C,Morohashi M

更新日期：2000-08-01 00:00:00

abstract：:We present a case of a 64-year-old man with refractory acute myeloid leukemia and trisomy 8 who developed leukemia cutis. Interphase fluorescence in situ hybridization (FISH) was performed on a paraffin-embedded skin section. FISH confirmed a population of cells with trisomy 8 in the blastic infiltrates involving the ...

journal_title：Journal of cutaneous pathology

authors： Shvartsbeyn M,Meehan SM,Gu P,Nierodzik ML,Perle MA

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Rare cases of a non-bullous neutrophilic dermatosis occurring in patients with lupus erythematosus (LE) have been reported, often as the presenting manifestation of the disease. METHODS:We reviewed hematoxylin and eosin-stained slides and obtained clinical information from four additional patients, two of w...

journal_title：Journal of cutaneous pathology

authors： Gleason BC,Zembowicz A,Granter SR

更新日期：2006-11-01 00:00:00

abstract：:Twenty-nine cases of histiocytic neoplasms, some resembling juvenile xanthogranuloma (JXG) and others resembling reticulohistiocytoma (RH), were evaluated. Immunohistochemical stains were performed. In this series, seven cases were identified that expressed S-100 protein positive cells. The S-100 positive cells were p...

journal_title：Journal of cutaneous pathology

authors： Tomaszewski MM,Lupton GP

更新日期：1998-03-01 00:00:00

abstract：:Nm23 is a gene with a putative metastasis-suppressor function, whose expression is inversely correlated with the metastatic potential of some solid malignancies. Because very few data exist concerning the role of nm23 in skin tumors, we studied the immunohistochemical expression of nm23 gene product in frozen sections...

journal_title：Journal of cutaneous pathology

authors： Kanitakis J,Euvrard S,Bourchany D,Faure M,Claudy A

更新日期：1997-03-01 00:00:00

abstract：AIM:In the absence of mites, the histologic diagnosis of human scabies can be difficult. Scabies can mimic a variety of inflammatory and lymphoproliferative disorders. It is under-recognized that scabies can also mimic Langerhans cell histiocytosis. METHODS:Sixteen examples of scabies were reviewed histologically and ...

journal_title：Journal of cutaneous pathology

authors： Bhattacharjee P,Glusac EJ

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:CD44 is a membrane glycoprotein and the major cell-surface receptor of hyaluronate (HA). Lack of CD44 expression in mouse epidermis leads to an abnormal HA accumulation in the dermis, indicating an important role of CD44 in local HA metabolism. Decrease of epidermal CD44 expression in patients of lichen scle...

journal_title：Journal of cutaneous pathology

authors： Kaya G,Augsburger E,Chavaz P,Saurat JH

更新日期：2006-03-01 00:00:00

abstract：:A 54-year-old female presented with the cutaneous metastases of the breast carcinoma that produced combination of pigmented zosteriform eruption on the trunk and eroded plaque on the scalp, 13 years after radical mastectomy. Histologically, zosteriform lesions displayed prominent infiltration of the epidermis in nesti...

journal_title：Journal of cutaneous pathology

authors： Brasanac D,Boricic I,Todorovic V

更新日期：2003-11-01 00:00:00

abstract：:Pigment-synthesizing melanoma (PSM) describes a morphologically and genetically diverse group of melanomas. In contrast, pigmented epithelioid melanocytoma (PEM) encompasses a spectrum of indolent tumors now classified as borderline/intermediate melanocytic tumors. Herein, we report a case of widely metastatic heavily...

journal_title：Journal of cutaneous pathology

authors： Motaparthi K,George EV,Guo R

更新日期：2019-08-01 00:00:00

abstract：:A 57-year-old woman with cutaneous mastocytosis of 23 years duration developed a hyperpigmented abdominal plaque composed of confluent indurated papules that enlarged for a period of 1 year to 12 x 8 cm. Biopsy showed dermal infiltration by closely packed spindle-shaped mast cells, fibroblasts, collagen, and scattered...

journal_title：Journal of cutaneous pathology

authors： Wood C,Sina B,Webster CG,Kurgansky D,Drachenberg CB,Reedy EA

更新日期：1992-04-01 00:00:00

abstract：:A 46-year-old man had a cystic mass on the right side of his scalp. Histological examination revealed a cystic dermal nodule composed of relatively circumscribed lobules of proliferating squamous epithelium, with atypical mitoses and dyskeratotic cells of invasive structure, which was diagnosed as proliferating tricho...

journal_title：Journal of cutaneous pathology

authors： Masui Y,Komine M,Kadono T,Ishiura N,Maekawa T,Ihn H,Kikuchi K,Tamaki K

更新日期：2008-10-01 00:00:00

abstract：:The internal organization of plasma membranes was studied in seven subjects with pemphigus vulgaris and in one subject with familial pemphigus using the freeze-fracture technique. The results obtained seem to suggest that the acantholytic process is produced in a similar fashion whatever the pathogenic agent and that ...

journal_title：Journal of cutaneous pathology

authors： Caputo R,Innocenti M,Gasparini G

更新日期：1980-04-01 00:00:00

abstract：:Merkel cell carcinoma is occasionally associated with other types of cutaneous malignancies including squamous cell carcinoma, basal cell carcinoma and lentigo maligna. We report a case of Merkel cell carcinoma co-existent with sebaceous carcinoma in the right upper eyelid of a 61-year-old Japanese man. Histopathologi...

journal_title：Journal of cutaneous pathology

authors： Tanahashi J,Kashima K,Daa T,Yada N,Fujiwara S,Yokoyama S

更新日期：2009-09-01 00:00:00

abstract：:The term hemangioendothelioma has been used in recent years to name a heterogeneous group of vascular neoplasms, intermediate in both biological behavior and histopathologic appearance between benign tumors (hemangiomas) and frankly malignant tumors (angiosarcomas). Thus, within the spectrum of hemangioendothelioma ha...

journal_title：Journal of cutaneous pathology

authors： Requena L,Luis Díaz J,Manzarbeitia F,Carrillo R,Fernández-Herrera J,Kutzner H

更新日期：2008-02-01 00:00:00

abstract：:Cutaneous mixed tumors (MTs), also known as chondroid syringomas, usually arise as small nodules in the head and neck region. We describe an unusual case of a giant MT measuring 9 cm in its greatest diameter, occurring as a slowly growing pedunculated mass on the breast of a 74-year-old woman. Although MT may rarely o...

journal_title：Journal of cutaneous pathology

authors： Magro G,Floridia F,Geraci G,Marino B

更新日期：2009-06-01 00:00:00

abstract：:Perifollicular fibroma is a cutaneous hamartomatous proliferation of the pilar connective tissue sheath. We describe a patient with multiple perifollicular fibromas and analyze the literature on this topic. Histologically, perifollicular fibroma is characterized by a concentric arrangement of collagen fibers surroundi...

journal_title：Journal of cutaneous pathology

authors： Junkins-Hopkins JM,Cooper PH

更新日期：1994-10-01 00:00:00