Merkel cell carcinoma co-existent with sebaceous carcinoma of the eyelid.

abstract：:A cystic panfolliculoma is a benign follicular neoplasm which recapitulates several portions of the hair follicle. The patient was a 64-year-old Caucasian female who presented with a new growth on her right forearm. The lesion had slowly enlarged over the previous 11 months. She complained of it bleeding on several oc...

journal_title：Journal of cutaneous pathology

authors： Neill B,Bingham C,Braudis K,Zurowski S

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND:Cutaneous lymphatic malformations represent a group of heterogeneous diseases caused by developmental defects of lymphatic system. OBJECTIVE:The purpose of this study was to report the clinical, histopathological and immunohistochemical features of a distinctive lymphatic malformation. METHODS:Twelve patie...

journal_title：Journal of cutaneous pathology

authors： Wang L,Gao T,Wang G

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Angiosarcomas arise in the scalp and face in the elderly, in association with chronic lymphedema (Stewart-Treves syndrome), and in irradiated areas. Rarely in these settings, angiosarcomas exhibit pure spindle cell phenotype. METHODS:Herein, the clinicopathologic features of a 72-year-old-woman with spindle...

journal_title：Journal of cutaneous pathology

authors： Kiyohara T,Kumakiri M,Kobayashl H,Itoh K,Lao LM,Ohkawara A,Nakmura H

更新日期：2002-02-01 00:00:00

abstract：:Nm23 is a gene with a putative metastasis-suppressor function, whose expression is inversely correlated with the metastatic potential of some solid malignancies. Because very few data exist concerning the role of nm23 in skin tumors, we studied the immunohistochemical expression of nm23 gene product in frozen sections...

journal_title：Journal of cutaneous pathology

authors： Kanitakis J,Euvrard S,Bourchany D,Faure M,Claudy A

更新日期：1997-03-01 00:00:00

abstract：:Xanthogranulomas are benign lesions composed of macrophages in which some of the cells have vacuolated cytoplasm. They commonly occur in children, referred to as juvenile xanthogranulomata, and are histopathologically characterized by the presence of Touton giant cells. Xanthogranuloma can also occur in adults. A woma...

journal_title：Journal of cutaneous pathology

authors： Cohen PR,Prieto VG

更新日期：2010-08-01 00:00:00

abstract：:This is the first report of spinous and follicular lichen nitidus associated with perifollicular granuloma formation. Clinicians and pathologists need to distinguish this stage of the disease from lichen scrofulosorum. ...

journal_title：Journal of cutaneous pathology

authors： Madhok R,Winkelmann RK

更新日期：1988-08-01 00:00:00

abstract：:The term hemangioendothelioma has been used in recent years to name a heterogeneous group of vascular neoplasms, intermediate in both biological behavior and histopathologic appearance between benign tumors (hemangiomas) and frankly malignant tumors (angiosarcomas). Thus, within the spectrum of hemangioendothelioma ha...

journal_title：Journal of cutaneous pathology

authors： Requena L,Luis Díaz J,Manzarbeitia F,Carrillo R,Fernández-Herrera J,Kutzner H

更新日期：2008-02-01 00:00:00

abstract：:White sponge nevus (WSN) is an uncommon benign inherited disorder characterized by white and diffuse painless lesions in oral, esophageal, or genital mucosa. The lesions may develop at birth or later in childhood or adolescence, with careful clinical examination being sufficient for diagnosis in most cases. However, m...

journal_title：Journal of cutaneous pathology

authors： Bezerra KT,Leite TC,Roza ALOC,Araújo R,Israel MS,Canedo NHS,Agostini M,Benevenuto de Andrade BA,Romañach MJ

更新日期：2020-01-01 00:00:00

abstract：:Pigmented extramammary Paget disease (PEMPD) is a rare intraepithelial carcinoma which can clinically resemble other pigmented neoplasms. Similarities to melanoma on dermoscopy, histopathology, and reflectance confocal microscopy (RCM) increase the risk of misdiagnosis and, consequently, mismanagement. Here, we descri...

journal_title：Journal of cutaneous pathology

authors： Chuchvara N,Reilly C,Haroon A,Wassef C,Maghari A,Rao B

更新日期：2020-12-01 00:00:00

abstract：:The non-specific clinical findings and variable histopathological features of cutaneous tuberculosis and non-tuberculous mycobacterial infections often make it difficult to establish a diagnosis and initiate appropriate therapy. We investigated 25 patients diagnosed with mycobacterial infections of the skin in Hanyang...

journal_title：Journal of cutaneous pathology

authors： Min KW,Ko JY,Park CK

更新日期：2012-06-01 00:00:00

abstract：:Verrucous hemangioma represents a rare congenital vascular proliferation that may be mistaken for angiokeratoma. Histopathological examination of a deep biopsy is necessary to confirm the diagnosis of verrucous hemangioma based on its involvement of the deep dermis and subcutaneous tissue. We present two cases of verr...

journal_title：Journal of cutaneous pathology

authors： Clairwood MQ,Bruckner AL,Dadras SS

更新日期：2011-09-01 00:00:00

abstract：:Cell adhesion between surfaces of cells and to extracellular matrices represents a fundamental mechanism in tissue organization and influences the biological behaviour and the architecture of tumors. We investigated the expression of various adhesion molecules in normal skin (n=5), nevi (n=29), and malignant melanoma ...

journal_title：Journal of cutaneous pathology

authors： Tronnier M,Alexander M,Wolff HH

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Benign lichenoid keratosis (BLK) is a well-known clinicopathologic entity and several histopathologic patterns have been described. Features mimicking mycosis fungoides (MF) in clinically typical BLKs have not yet been emphasized. The aim of this study was to confirm the occurrence of an MF-like pattern of B...

journal_title：Journal of cutaneous pathology

authors： Al-Hoqail IA,Crawford RI

更新日期：2002-05-01 00:00:00

abstract：:Subungual melanoma commonly presents with solitary longitudinal melanonychia. Herein, we report the case of a patient with subungual melanoma who developed involvement of three digits by three independent primary melanomas. A 98-year-old male patient presented with a two-year history of longitudinal melanonychia on th...

journal_title：Journal of cutaneous pathology

authors： Liu Y,Wang L

更新日期：2012-02-01 00:00:00

abstract：:Accessory breast tissue is a subcutaneous remnant persisting after normal embryological development of the breast. It occurs most frequently in the axilla. Fibroadenomas in axillary breast tissue are rare. We report the case of a 29-year-old female patient who presented a fibroadenoma arising in the accessory breast t...

journal_title：Journal of cutaneous pathology

authors： Val-Bernal JF,González-Vela MC,De Grado M,Garijo MF

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Pigmentation is a characteristic clinical feature of basal cell carcinomas (BCCs) in Japanese patients. The pathogenesis of melanin pigment in pigmented BCCs is poorly understood. METHODS:We have combined the techniques of morphometric analysis and electron microscopy to assess accurately the morphologic as...

journal_title：Journal of cutaneous pathology

authors： Lao LM,Kumakiri M,Kiyohara T,Kuwahara H,Ueda K

更新日期：2001-01-01 00:00:00

abstract：:Cutaneous lymphadenoma is an uncommon benign neoplasm often considered to be an adamantinoid variant of trichoblastoma. Lesions present in both sexes, between 14 and 87 years of age, and are mainly located on the head and neck. Cases in children are rare and there is only 1 previous case of a congenital lymphadenoma. ...

journal_title：Journal of cutaneous pathology

authors： Fernandez-Flores A,Nicklaus-Wollenteit I,Sathishkumar D,Diba V,Richard B,Carr R,Moss C,Nagy A,Ogboli M,Colmenero I

更新日期：2017-11-01 00:00:00

abstract：INTRODUCTION:Granulomatous mycosis fungoides (MF) is a rare variant in which granulomas are associated with other typical signs of MF. Its prognosis is worse than that of classical MF. Plasmacytoid dendritic cells (PDCs) are a subset of interferon-producing dendritic cells that link the innate and the adaptative immune...

journal_title：Journal of cutaneous pathology

authors： Fernandez-Flores A,Cassarino DS

更新日期：2019-05-01 00:00:00

abstract：:Epidermal growth factor (EGF) and transforming growth factor alpha (TGF alpha) are important keratinocyte mitogens. Their effects are mediated by a cell membrane receptor (EGFR), quantitative and qualitative abnormalities of which may be responsible for deranged keratinocyte proliferation and differentiation. We have ...

journal_title：Journal of cutaneous pathology

authors： Groves RW,Allen MH,MacDonald DM

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:Src-family tyrosine kinases (SFKs) are important regulators of keratinocyte growth and differentiation. In a broad range of cell types, persistent activation of SFKs correlates with increased cell proliferation. In this study, we determined if SFK activity is increased in cutaneous neoplasia and psoriasis, c...

journal_title：Journal of cutaneous pathology

authors： Ayli EE,Li W,Brown TT,Witkiewicz A,Elenitsas R,Seykora JT

更新日期：2008-03-01 00:00:00

abstract：:Discrete junctional cellular aggregates ("nests"), partially staining with melanocytic markers, are described in lichenoid tissue reaction, mainly from chronically sun-exposed skin. The concomitant epidermal flattening and papillary dermal fibrosis with melanophages, may raise the differential diagnosis to that of a r...

journal_title：Journal of cutaneous pathology

authors： Ferrara G,Bradamante M,Broglia I,Petrillo G,Stefanato CM

更新日期：2020-07-01 00:00:00

abstract：:The internal organization of plasma membranes was studied in seven subjects with pemphigus vulgaris and in one subject with familial pemphigus using the freeze-fracture technique. The results obtained seem to suggest that the acantholytic process is produced in a similar fashion whatever the pathogenic agent and that ...

journal_title：Journal of cutaneous pathology

authors： Caputo R,Innocenti M,Gasparini G

更新日期：1980-04-01 00:00:00

abstract：BACKGROUND:Ulceration and osteoclast-like giant cells are two pathological features uncommonly seen in dermatofibromas. To our knowledge, the presence of these features has not been previously described within the same lesion. METHODS:We report the clinical, histopathological and immunohistochemical findings of a 38-y...

journal_title：Journal of cutaneous pathology

authors： González-Vilas D,García-Gavín J,Ginarte M,Rodríguez-Blanco I,Toribio J

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Distinguishing an irritated seborrheic keratosis (ISK) from a squamous cell carcinoma in situ (SCCIS) can occasionally be challenging, both histologically and clinically. The purpose of this study was to determine if an immunohistochemical profile of select markers can aid in differentiating these two entiti...

journal_title：Journal of cutaneous pathology

authors： Richey JD,Deng AC,Dresser K,O'Donnell P,Cornejo KM

更新日期：2018-08-01 00:00:00

abstract：:A 24-year-old black woman from Uganda was seen for treatment of multiple papules on her hands and feet. The lesions corresponded microscopically to foci of hyperkeratosis and acanthosis. Acid orcein stain revealed marked elastic fiber fragmentation. Acrokeratoelastoidosis of Costa (AKE) was diagnosed. The same damage ...

journal_title：Journal of cutaneous pathology

authors： Fiallo P,Pesce C,Brusasco A,Nunzi E

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is associated with an increased risk of a second malignancy. METHODS:We conducted a retrospective clinicopathologic review of 12 patients with CLL/SLL who developed a second lymphoma in the skin. Demographic data, clinical information, and hi...

journal_title：Journal of cutaneous pathology

authors： Liu YA,Finn AJ,Subtil A

更新日期：2021-01-07 00:00:00

abstract：:Trichilemmoma is considered a benign neoplasm derived from the outer root sheath of the hair follicle. Although the histogenesis of the lesion is unknown, a relationship between human papillomavirus (HPV) infection and development of these tumors has been suggested on morphologic observations. In order to determine wh...

journal_title：Journal of cutaneous pathology

authors： Leonardi CL,Zhu WY,Kinsey WH,Penneys NS

更新日期：1991-06-01 00:00:00

abstract：:Lesions of seborrheic keratoses were studied by scanning electrom microscopy. Numerous yeasts were present on the karatinized cells and hairs associated with the lesions. Surfaces of some yeasts were smooth and others were ruffled. The ruffles suggested the presence of a glycocalyx. The yeasts exhibited the morphologi...

journal_title：Journal of cutaneous pathology

authors： Wilborn WH,Montes LF

更新日期：1980-02-01 00:00:00

abstract：:We present the case of a 77-year-old male undergoing treatment for mycosis fungoides (MF) who presented for removal of an acrochordon on his mid back. Histopathologic examination of the acrochordon revealed a dense, band-like lymphocytic inflammatory infiltrate in the dermis with epidermotropism of single lymphocytes ...

journal_title：Journal of cutaneous pathology

authors： McClain CM,Cole MB,Robbins JB,Kantrow SM

更新日期：2012-12-01 00:00:00

abstract：:Lymphomatoid granulomatosis (LG) is a rare Epstein-Barr virus (EBV)-associated B-cell lymphoproliferative disorder presenting in middle adulthood that nearly always affects the lungs and shows cutaneous involvement in up to 50% of cases. Skin lesions are present at the time of diagnosis in roughly one-third of patient...

journal_title：Journal of cutaneous pathology

authors： Rysgaard CD,Stone MS

更新日期：2015-03-01 00:00:00