Distinguishing between irritated seborrheic keratosis and squamous cell carcinoma in situ using BCL-2 and IMP3 immunohistochemistry.

abstract：:Perifollicular fibroma is a cutaneous hamartomatous proliferation of the pilar connective tissue sheath. We describe a patient with multiple perifollicular fibromas and analyze the literature on this topic. Histologically, perifollicular fibroma is characterized by a concentric arrangement of collagen fibers surroundi...

journal_title：Journal of cutaneous pathology

authors： Junkins-Hopkins JM,Cooper PH

更新日期：1994-10-01 00:00:00

abstract：:Angioimmunoblastic T-cell lymphoma (AITL) is an aggressive form of peripheral T-cell lymphoma, characterized by systemic symptoms, diffuse lymphadenopathy, hepatosplenomegaly and immunodysregulation. Half of AITL is associated with cutaneous symptoms, but only few cases with bullous eruption have been described. Assoc...

journal_title：Journal of cutaneous pathology

authors： Colmant C,Camboni A,Dekeuleneer V,Marot L,Dachelet C,Baeck M

更新日期：2020-03-01 00:00:00

abstract：:A 48 year-old white male with basal cell nevus syndrome presented with a metastatic basal cell carcinoma with neuroendocrine features. The tumor manifested aggressive behavior, having deep local invasion and metastases to para-aortic lymph nodes and bone. Neuroendocrine differentiation has rarely been associated with ...

journal_title：Journal of cutaneous pathology

authors： Tawfik O,Casparian JM,Garrigues N,Smith S,Kestenbaum T,Chamberlin F,Khan QS

更新日期：1999-07-01 00:00:00

abstract：:Infundibulocystic basal cell carcinoma (IBCC) is a relatively recently described variant of basal cell carcinoma that is controversial and not universally accepted. Excluding cases of nevoid basal cell carcinoma syndrome, IBCC usually presents as a small, solitary, superficial lesion on the face of older persons. Ther...

journal_title：Journal of cutaneous pathology

authors： Kagen MH,Hirsch RJ,Chu P,McCormack PC,Weinberg JM

更新日期：2000-07-01 00:00:00

abstract：:Merkel cell carcinoma is occasionally associated with other types of cutaneous malignancies including squamous cell carcinoma, basal cell carcinoma and lentigo maligna. We report a case of Merkel cell carcinoma co-existent with sebaceous carcinoma in the right upper eyelid of a 61-year-old Japanese man. Histopathologi...

journal_title：Journal of cutaneous pathology

authors： Tanahashi J,Kashima K,Daa T,Yada N,Fujiwara S,Yokoyama S

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Recent genetic investigations support the idea that basal cell carcinoma (BCC) is trichoblastic carcinoma. However, it is generally thought that clear cell basal cell carcinoma is a result of degeneration rather than tricholemmal differentiation. METHODS:We report a case of BCC, with clear cell components, ...

journal_title：Journal of cutaneous pathology

authors： Misago N,Satoh T,Narisawa Y

更新日期：2003-03-01 00:00:00

abstract：:Verruciform xanthoma (VX) is an uncommon lesion occurring primarily in the oral cavity. Cutaneous lesions are much less common and they preferentially arise on anogenital skin. They are not necessarily associated with a pre-existing inflammatory process. We report a VX in association with a long-standing lesion of dis...

journal_title：Journal of cutaneous pathology

authors： Meyers DC,Woosley JT,Reddick RL

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:Recently, an intriguing concept was introduced into the literature that defines the area underlying the nail bed as a specific mesenchymal substructure unique to the nail organ. It has been termed onychodermis. The onychodermis expresses CD10 with remarkable specificity. Herein, we compare adult and fetal hu...

journal_title：Journal of cutaneous pathology

authors： Sellheyer K,Nelson P

更新日期：2013-05-01 00:00:00

abstract：:Dermatomyositis, a connective tissue disease syndrome where antibodies to the endothelium of the microvasculature of the skin, muscle and lung are implicated in lesional propagation, is characterized by photodistributed erythema, heliotrope rash, Gottron's papules, muscle weakness and interstitial pulmonary fibrosis. ...

journal_title：Journal of cutaneous pathology

authors： Magro CM,Schaefer JT,Waldman J,Knight D,Seilstad K,Hearne D

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Although a range of cytomegalovirus (CMV)-induced cutaneous manifestations is described in AIDS patients, skin involvement in immunocompromised patients is rare, and intraneural CMV inclusions or CMV neuritis has not been documented in skin biopsies. METHODS AND RESULTS:Cutaneous biopsies of CMV lesions wer...

journal_title：Journal of cutaneous pathology

authors： Ramdial PK,Dlova NC,Sydney C

更新日期：2002-08-01 00:00:00

abstract：:Primary cutaneous extranodal marginal zone lymphoma (MZL) of mucosa-associated lymphoid tissue (MALT) represents a monoclonal B-cell neoplasm that typically presents with papules, plaques or nodules. We describe a patient with a primary cutaneous MALT lymphoma with unusual clinical features and an unusual immunophenot...

journal_title：Journal of cutaneous pathology

authors： Edinger JT,Lorenzo CR,Breneman DL,Swerdlow SH

更新日期：2011-09-01 00:00:00

abstract：:A 35-year-old woman was examined because of a symptomless multiple annular eruption. The lesion consisted of rings of closely set, smooth, firm papules that were brown in color. Hemosiderotic histiocytoma was diagnosed by light and electron microscopy. Ultrastructurally, the lesion consisted of fibroblastic and histio...

journal_title：Journal of cutaneous pathology

authors： Saga K

更新日期：1981-06-01 00:00:00

abstract：:Clear cell atypical fibroxanthoma (CCAFX) is a rare variant of atypical fibroxanthoma (AFX), a pleomorphic dermal tumour associated with a good prognosis. A 67-year-old man presented with a rapidly growing nodule on the ear, which had appeared over a 2-week period. Sections showed an ulcerated nodule composed of pleom...

journal_title：Journal of cutaneous pathology

authors： Murali R,Palfreeman S

更新日期：2006-05-01 00:00:00

abstract：:Adult-onset Still disease (AOSD) is a rare autoinflammatory syndrome characterized by recurring fevers, arthralgia, and consistent laboratory abnormalities that include leukocytosis and hyperferritinemia. Skin findings accompany the disease in nearly 90% of the cases. Early reports described evanescent, pruritic, salm...

journal_title：Journal of cutaneous pathology

authors： Santa E,McFalls JM,Sahu J,Lee JB

更新日期：2017-06-01 00:00:00

abstract：:Lymphomatoid granulomatosis (LG) is a rare Epstein-Barr virus (EBV)-associated B-cell lymphoproliferative disorder presenting in middle adulthood that nearly always affects the lungs and shows cutaneous involvement in up to 50% of cases. Skin lesions are present at the time of diagnosis in roughly one-third of patient...

journal_title：Journal of cutaneous pathology

authors： Rysgaard CD,Stone MS

更新日期：2015-03-01 00:00:00

abstract：:Biopsies from a 5-year-old girl with dermatomyositis and universal calcinosis were studied histopathologically and by means of electron optical techniques. The dermis was infiltrated by fibroblasts, lymphocytes and plasma cells. In the lower part of the dermis, dense basophilic areas were present. In the vicinity of t...

journal_title：Journal of cutaneous pathology

authors： Nielsen AO,Johnson E,Hentzer B,Kobayasi T

更新日期：1979-12-01 00:00:00

abstract：:Lobular capillary hemangioma, which is also named as pyogenic granuloma, is a common vascular proliferation of skin and mucous membranes. Hormonal influence in the development of lobular capillary hemangioma on the mucosal surfaces has been demonstrated but for cutaneous lesions located on the skin, this association h...

journal_title：Journal of cutaneous pathology

authors： Demir Y,Demir S,Aktepe F

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Hypertrophic lichen planus (LP) is a variant of LP favoring the lower extremities and showing prominent epidermal hyperplasia and hyperorthokeratosis. Contrary to dogma that eosinophils are rare in LP and variants, we noticed that some cases of hypertrophic LP have eosinophils in the absence of drug history....

journal_title：Journal of cutaneous pathology

authors： Alomari A,McNiff JM

更新日期：2014-04-01 00:00:00

abstract：:Sarcoidosis is a granulomatous condition with diverse clinical presentations, including neurological findings. It was previously hypothesized that perineural sarcoidal granulomas in the skin may be an explanation of small-fiber neuropathy. Herein, we present a case of a 55 year old female with anesthetic cutaneous les...

journal_title：Journal of cutaneous pathology

authors： Kazi R,Kazlouskaya V,Ho J,Karunamurthy A

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Despite its occasional unavailability, alcian blue has long been the stain of choice for the pathognomonic mucin-secreting cells of extramammary Paget's disease. Zirconyl hematoxylin is a recently developed substitute for alcian blue, which is made from common laboratory materials. METHODS:We have stained s...

journal_title：Journal of cutaneous pathology

authors： Smith AA,Silver TM

更新日期：2003-07-01 00:00:00

abstract：:Epidermolytic hyperkeratosis (EH) is a well-described histopathologic pattern characteristic of bullous congenital ichthyosiform erythroderma, an autosomal dominant genodermatosis. It is also noted in cutaneous disorders where mosaicism leads to containment of the clinical and histopathologic changes. EH has been obse...

journal_title：Journal of cutaneous pathology

authors： Steele CL,Shea CR,Petronic-Rosic V

更新日期：2007-04-01 00:00:00

abstract：:Although CD1a+ dendritic cells (DC) in cutaneous T-cell lymphomas (CTCL) have been well documented, the presence of large numbers of DC within lymphoid infiltrates can pose a diagnostic difficulty. We present a case of a 70-year-old man with a 3-year history of recurrent red papules and plaques on the extremities and ...

journal_title：Journal of cutaneous pathology

authors： Jokinen CH,Wolgamot GM,Wood BL,Olerud J,Argenyi ZB

更新日期：2007-07-01 00:00:00

abstract：:Twenty-nine cases of histiocytic neoplasms, some resembling juvenile xanthogranuloma (JXG) and others resembling reticulohistiocytoma (RH), were evaluated. Immunohistochemical stains were performed. In this series, seven cases were identified that expressed S-100 protein positive cells. The S-100 positive cells were p...

journal_title：Journal of cutaneous pathology

authors： Tomaszewski MM,Lupton GP

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:The present study evaluates the signal transducer and activator of transcription-3 (STAT-3) expression and activation in actinic cheilitis (AC) and the relationship of this protein with the degree of epithelial dysplasia. METHODS:Twenty-five cases of AC were analyzed. Normal lip mucosa was used as a control...

journal_title：Journal of cutaneous pathology

authors： Cury PR,Furuse C,de Araújo NS,de Araújo VC

更新日期：2007-08-01 00:00:00

abstract：:Benign lymphangioendothelioma is a rare locally infiltrative vascular neoplasm, presenting as a slow-growing, asymptomatic, reddish-violaceous plaque. Histopathologically, it is characterized by irregular and thin-walled vascular spaces, lined by a single and discontinuous layer of flat endothelial cells, dissecting d...

journal_title：Journal of cutaneous pathology

authors： Revelles JM,Díaz JL,Angulo J,Santonja C,Kutzner H,Requena L

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Apoptosis is important for maintenance of tissue homeostasis and often dysregulated in cutaneous neoplasms. The apoptosis inhibitor survivin is expressed in melanoma and non-melanoma skin cancers and benign keratinocytic lesions. Its expression has not been studied in melanocytic nevi. OBJECTIVE:We determin...

journal_title：Journal of cutaneous pathology

authors： Florell SR,Bowen AR,Hanks AN,Murphy KJ,Grossman D

更新日期：2005-01-01 00:00:00

abstract：:The nuclei of spindle and epithelioid cell nevus (SECN) cells often contain inclusions. To determine the origin and pathogenesis of the nuclear inclusions, 12 cases of SECN were electron microscopically examined. True inclusions, pseudoinclusions, and electron-lucent areas were frequently found in the nuclei of SECN c...

journal_title：Journal of cutaneous pathology

authors： Sakamoto F,Ito M,Sato Y

更新日期：1990-04-01 00:00:00

abstract：:We reviewed the clinical, histologic, and immunofluorescence features of 20 patients with pemphigus and neoplasia and compared them with a control group of 17 patients with pemphigus without neoplasia. Patients with neoplasia were divided according to clinical, histologic, and immunofluorescence findings into those wi...

journal_title：Journal of cutaneous pathology

authors： Mehregan DR,Oursler JR,Leiferman KM,Muller SA,Anhalt GJ,Peters MS

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:Fatty acid synthase (FAS), the key enzyme responsible for the synthesis of fatty acids, is weakly expressed in some normal human tissues. Recently, FAS has been demonstrated to be overexpressed in many non-neoplastic highly proliferative lesions and in aggressive carcinomas with poor outcome, including colon...

journal_title：Journal of cutaneous pathology

authors： Innocenzi D,Alò PL,Balzani A,Sebastiani V,Silipo V,La Torre G,Ricciardi G,Bosman C,Calvieri S

更新日期：2003-01-01 00:00:00

abstract：:The majority of findings in relation to warts have been passed on from one textbook to the other since the end of the last century. More recent studies have been carried out with the electron microscope. But information is lacking as to histology, histochemistry, examination with the phase-contrast microscope, with th...

journal_title：Journal of cutaneous pathology

authors： Steigleder GK

更新日期：1978-04-01 00:00:00