Abstract：
:The majority of findings in relation to warts have been passed on from one textbook to the other since the end of the last century. More recent studies have been carried out with the electron microscope. But information is lacking as to histology, histochemistry, examination with the phase-contrast microscope, with the interference microscope, microradiography and other new techniques. Warts are a proliferation of the epidermis caused by a virus, and we know that the culprit acts in the epidermis itself. Warts are acanthomas, and a transition to malignancy is possible in predisposed persons. It is most remarkable that in the malignant tumors of epidermodysplasia verruciformis, no virus could be found. As the demonstration of viruses with the electron microscope and other techniques cannot be made as a matter of routine, we have to search for a simpler method with the light microscope. With the application of more elaborate procedures, new information about epidermal proliferation will certainly be obtained.
journal_name
J Cutan Patholjournal_title
Journal of cutaneous pathologyauthors
Steigleder GKdoi
10.1111/j.1600-0560.1978.tb00938.xsubject
Has Abstractpub_date
1978-04-01 00:00:00pages
45-52issue
2eissn
0303-6987issn
1600-0560journal_volume
5pub_type
杂志文章abstract：BACKGROUND:Long-term preservation of immunofluorescence is important for re-examinations. We investigated whether the storage of direct immunofluorescent (DIF)-positive slides at room temperature was reliable in daily practice. METHODS:One hundred and twenty-five DIF-positive slides from the skin of 52 patients were e...
journal_title：Journal of cutaneous pathology
pub_type： 杂志文章
doi：10.1034/j.1600-0560.2003.00071.x
更新日期：2003-08-01 00:00:00
abstract：:Amyloidosis cutis dyschromica represents a rare type of primary cutaneous amyloidosis with few reported cases worldwide. It is characterized by asymptomatic, generalized hyperpigmentation with intermingled hypopigmented macules without atrophy or telangiectasia. We report herein a 19-year-old female who developed this...
journal_title：Journal of cutaneous pathology
pub_type： 杂志文章
doi：10.1111/j.1600-0560.2011.01701.x
更新日期：2011-10-01 00:00:00
abstract：BACKGROUND:We encountered a distinctive pattern of dysplastic intraepidermal melanocytic proliferation, which defies classification as a dysplastic melanocytic nevus, but in which the morphologic features fall short of a diagnosis of melanoma in situ. We designate such lesions as de novo intraepidermal epithelioid mela...
journal_title：Journal of cutaneous pathology
pub_type： 杂志文章
doi：10.1111/j.0303-6987.2005.00314.x
更新日期：2005-10-01 00:00:00
abstract：:Clinical and histologic features of 44 invasive squamous cell carcinomas of the lip treated by surgical excision were correlated with metastases and survival. Age, diameter, ulceration, grade, depth of invasion, muscle invasion, mitotic rate, lymphatic-vascular invasion, and tumor infiltrating lymphocytes were evaluat...
journal_title：Journal of cutaneous pathology
pub_type： 杂志文章
doi：10.1111/j.1600-0560.1994.tb00685.x
更新日期：1994-02-01 00:00:00
abstract：:Formalin-fixed, paraffin-embedded biopsy specimens of 17 cases of squamous cell carcinoma of Marjolin's ulcer (SCC-MU), 6 cases of common SCC (SCC), and 5 cases of basal cell carcinoma (BCC) were stained with three monoclonal antikeratin antibodies (CAM 5.2, MAK-6, and MA-903), a monoclonal antivimentin antibody (V9),...
journal_title：Journal of cutaneous pathology
pub_type： 杂志文章
doi：10.1111/j.1600-0560.1992.tb01363.x
更新日期：1992-08-01 00:00:00
abstract：BACKGROUND:The distinction between ocular sebaceous carcinoma, poorly differentiated ocular squamous cell carcinoma and ocular basal cell carcinoma can be challenging. An appropriate immunohistochemical panel may help to differentiate these lesions. METHODS:To determine the distribution and use of several immunostains...
journal_title：Journal of cutaneous pathology
pub_type： 杂志文章
doi：10.1111/j.1600-0560.2007.00871.x
更新日期：2008-07-01 00:00:00
abstract：BACKGROUND:The importance of changes in the supporting tumor stroma for cancer initiation and progression is well established. The characteristics of an activated tumor stroma, however, are not completely understood. In an effort to better characterize the desmoplastic response to human skin tumors, we evaluated the ex...
journal_title：Journal of cutaneous pathology
pub_type： 杂志文章
doi：10.1111/j.0303-6987.2006.00446.x
更新日期：2006-02-01 00:00:00
abstract：BACKGROUND:Diagnosis of autoantibody- and immune complex-induced skin diseases is primarily based on direct immunofluorescence (DIF) microscopy. DIF staining is usually performed manually and, therefore, is labor intensive. The quality of immunohistochemical results considerably depends on the experience of the person ...
journal_title：Journal of cutaneous pathology
pub_type： 杂志文章
doi：10.1111/cup.12637
更新日期：2016-03-01 00:00:00
abstract：:We encountered a patient who complained of many small papules on the neck, shoulders, upper chest and upper back. Biopsy specimens showed complete loss of elastic fibers in the upper dermis including papillary dermis, whereas those of the mid dermis were intact. Electron microscopy revealed that assembly of component ...
journal_title：Journal of cutaneous pathology
pub_type： 杂志文章
doi：10.1111/j.1600-0560.1994.tb00724.x
更新日期：1994-12-01 00:00:00
abstract：:Dermal non-neural granular cell tumor (NNGCT) was first described in 1991 as an S100-negative polypoid non-melanocytic tumor. Although originally introduced in the literature as a primary cutaneous tumor, it was later emphasized that such qualification could not be held until the line of differentiation was clarified....
journal_title：Journal of cutaneous pathology
pub_type： 杂志文章
doi：10.1111/cup.12926
更新日期：2017-06-01 00:00:00
abstract：:A tumor of 60 years' duration overlying the sternum of an 87-year-old woman is described. Histologically, the tumor was composed of lobules and cords of epithelial cells with finely granular, eosinophilic cytoplasm. The epithelial nests were floating in large pools of mucinous stroma, separated by thin fibrovascular s...
journal_title：Journal of cutaneous pathology
pub_type： 杂志文章
doi：10.1111/j.1600-0560.1991.tb00140.x
更新日期：1991-04-01 00:00:00
abstract：:The bcl-2 proto-oncogene encodes a protein that protects cells from programmed cell death (apoptosis). High levels of this protein confer a growth advantage to neoplastic cells even in the absence of a high mitotic rate. This gene is involved in the interchromosomal 14;18 translocation, an abnormality present in more ...
journal_title：Journal of cutaneous pathology
pub_type： 杂志文章
doi：10.1111/j.1600-0560.1994.tb00279.x
更新日期：1994-10-01 00:00:00
abstract：:A case is presented of white plaques occurring predominantly on the vulvar mucosa of a 28-year-old female diagnosed as white sponge nevus (WSN). WSN is a rare, autosomal dominant disorder involving mucous membranes. It predominantly affects the oral mucosa; however, it has been reported to rarely involve extraoral muc...
journal_title：Journal of cutaneous pathology
pub_type： 杂志文章
doi：10.1111/j.1600-0560.2009.01294.x
更新日期：2010-03-01 00:00:00
abstract：BACKGROUND:Cutaneous lymphocyte-associated antigen (CLA) is expressed in resident cutaneous T lymphocytes, high endothelial venules, peripheral monocytes, granulocytes and a small percentage of memory B cells. It has been postulated to be an important factor in homing of lymphocytes to the skin because of its function ...
journal_title：Journal of cutaneous pathology
pub_type： 杂志文章
doi：10.1111/j.1600-0560.2007.00971.x
更新日期：2008-11-01 00:00:00
abstract：:Merkel cell carcinoma is occasionally associated with other types of cutaneous malignancies including squamous cell carcinoma, basal cell carcinoma and lentigo maligna. We report a case of Merkel cell carcinoma co-existent with sebaceous carcinoma in the right upper eyelid of a 61-year-old Japanese man. Histopathologi...
journal_title：Journal of cutaneous pathology
pub_type： 杂志文章
doi：10.1111/j.1600-0560.2008.01160.x
更新日期：2009-09-01 00:00:00
abstract：:Spontaneous regression (SR) of cancer is a rare but well-documented biological phenomenon, which is even rarer in the context of metastatic breast carcinoma. Different mechanisms of SR are still under debate, including immune-mediated response. We herein report a case of the SR of intralymphatic cutaneous metastases o...
journal_title：Journal of cutaneous pathology
pub_type：
doi：10.1111/cup.13694
更新日期：2020-08-01 00:00:00
abstract：:The so-called perivascular epithelioid cell neoplasm (PEComa) family includes angiomyolipoma, clear cell 'sugar' tumor (CCST), lymphangioleiomyomatosis, and clear cell myomelanocytic tumor (CCMMT). These rare tumors are characterized by the co-expression of melanocytic and muscle markers. They have been recognized in ...
journal_title：Journal of cutaneous pathology
pub_type： 杂志文章
doi：10.1111/j.0303-6987.2005.00347.x
更新日期：2005-07-01 00:00:00
abstract：:A case of squamous cell carcinoma (SCC) with regional lymph node metastasis in a 69-year-old Japanese man is reported. The tumor was characterized by the proliferation of peripheral basaloid, inner squamoid, and glycogen-rich cells, the presence of trichilemmal keratinization, and the presence of ladder-like, membrane...
journal_title：Journal of cutaneous pathology
pub_type： 杂志文章
doi：10.1111/j.1600-0560.1991.tb01240.x
更新日期：1991-08-01 00:00:00
abstract：BACKGROUND:Pigmentation is a characteristic clinical feature of basal cell carcinomas (BCCs) in Japanese patients. The pathogenesis of melanin pigment in pigmented BCCs is poorly understood. METHODS:We have combined the techniques of morphometric analysis and electron microscopy to assess accurately the morphologic as...
journal_title：Journal of cutaneous pathology
pub_type： 杂志文章
doi：10.1034/j.1600-0560.2001.280104.x
更新日期：2001-01-01 00:00:00
abstract：:Facial inflammatory dermatoses can be difficult to diagnose in their early stages; skin biopsy may help but often shows indeterminate features. The aims of our study were to identify patients presenting with a facial dermatosis requiring skin biopsy, in whom the initial histological features were classified as "non-sp...
journal_title：Journal of cutaneous pathology
pub_type： 杂志文章
doi：10.1111/j.1600-0560.1995.tb01400.x
更新日期：1995-04-01 00:00:00
abstract：:Verrucous hemangioma represents a rare congenital vascular proliferation that may be mistaken for angiokeratoma. Histopathological examination of a deep biopsy is necessary to confirm the diagnosis of verrucous hemangioma based on its involvement of the deep dermis and subcutaneous tissue. We present two cases of verr...
journal_title：Journal of cutaneous pathology
pub_type： 杂志文章,评审
doi：10.1111/j.1600-0560.2011.01733.x
更新日期：2011-09-01 00:00:00
abstract：:A patient with chronic myelocytic leukemia (CML) in blast transformation with extensive involvement of the skin is reported. The leukemic infiltrates consisted of blasts with lymphoblastoid morphology which were positive for terminal deoxynucleotidyl transferase (TdT) by fluorescent assay. The infiltrates rapidly reso...
journal_title：Journal of cutaneous pathology
pub_type： 杂志文章
doi：10.1111/j.1600-0560.1980.tb01199.x
更新日期：1980-10-01 00:00:00
abstract：BACKGROUND:Cardiac angiosarcoma is a rare tumor that has a predilection for middle-aged males and a marked predominance in the right atrium. The tumor may present abruptly with a fulminant clinical course. Initial presentation with metastatic disease is rare. Only one case has been reported of a patient who presented w...
journal_title：Journal of cutaneous pathology
pub_type： 杂志文章
doi：10.1034/j.1600-0560.2001.028005265.x
更新日期：2001-05-01 00:00:00
abstract：:We studied the degenerative "ancient" changes in 19 cases of benign cutaneous schwannoma (BCS). Using conventional and immunohistochemical stains, we found (a) degenerative changes in 15 of 19 BCS; (b) prominent vascular abnormalities in 11 of 15 BCS; and (c) cytologic atypia in 15 of 19 BCS, without mitotic figures. ...
journal_title：Journal of cutaneous pathology
pub_type： 杂志文章
doi：10.1111/j.1600-0560.1993.tb00232.x
更新日期：1993-04-01 00:00:00
abstract：BACKGROUND:The Fli-1 transcription factor functions in cellular proliferation and tumorigenesis. Its role in various neoplasms and its presence in lymphocytes suggest a link between Fli-1 dysregulation and the pathogenesis of mycosis fungoides (MF). In this study, we further elucidate this possible link. METHODS:Secti...
journal_title：Journal of cutaneous pathology
pub_type： 杂志文章
doi：10.1111/j.1600-0560.2006.00535.x
更新日期：2006-09-01 00:00:00
abstract：:Cutaneous syncytial myoepithelioma (CSM) is a recently recognized, histopathological variant of myoepithelial (ME) tumors of the skin. It is characterized by a syncytial arrangement of spindled, ovoid, and/or epithelioid cells forming a well-circumscribed, unencapsulated dermal nodule. There is a paucity of intervenin...
journal_title：Journal of cutaneous pathology
pub_type：
doi：10.1111/cup.13450
更新日期：2019-06-01 00:00:00
abstract：:The lesions of nine patients with early striae distensae (SD) during puberty were examined by light and electron microscopy. Specific changes were seen in very early stage SD, and in clinically uninvolved skin 0.5 to 3 cm remote from the edge of the long axis of the SD lesions. Sequential changes of elastolysis accomp...
journal_title：Journal of cutaneous pathology
pub_type： 杂志文章
doi：10.1111/j.1600-0560.1991.tb01376.x
更新日期：1991-12-01 00:00:00
abstract：:Mycosis fungoides (MF) is a rare type of non-Hodgkin's lymphoma affecting the skin. Because MF develops slowly over several years and may have a variety of clinical presentations, including itchy patches, plaques or tumors that may be confused with common benign conditions such as eczema and psoriasis, the disease pre...
journal_title：Journal of cutaneous pathology
pub_type： 杂志文章,评审
doi：10.1111/j.1600-0560.2006.00662.x
更新日期：2007-07-01 00:00:00
abstract：BACKGROUND:Glial cell line-derived neurotrophic factor (GDNF) and a related family member, neurturin (NTN), as well as their cognate receptors (GDNF receptors, GFRalpha-1 and GFRalpha-2, respectively) are involved in nervous system development and murine hair cycle control. To date, their expression in human scalp skin...
journal_title：Journal of cutaneous pathology
pub_type： 杂志文章
doi：10.1111/j.1600-0560.2006.00561.x
更新日期：2006-12-01 00:00:00
abstract：:We studied two cases of pigmented neuroectodermal tumor of infancy (PNTI) by routine light microscopy and immunohistochemistry on formalin fixed, paraffin embedded tissues using antibodies to HMB-45 "melanoma associated" antigen, S-100 protein, neuron specific enolase (NSE), Leu-7 antigen, chromogranin, epithelial mem...
journal_title：Journal of cutaneous pathology
pub_type： 杂志文章
doi：10.1111/j.1600-0560.1991.tb00600.x
更新日期：1991-02-01 00:00:00
