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Outcome of facial rashes with non-specific histological features: a long-term follow-up of 64 cases.

Abstract：

:Facial inflammatory dermatoses can be difficult to diagnose in their early stages; skin biopsy may help but often shows indeterminate features. The aims of our study were to identify patients presenting with a facial dermatosis requiring skin biopsy, in whom the initial histological features were classified as "non-specific", to determine the eventual diagnostic outcome, and to attempt to identify subtle early histologic features. We located 79 such cases with indeterminate histology from 45,000 dermatopathology reports 1972-1987. The original biopsies were assessed and scored using a check-list of 20 features and the patients' case-records up to 1992 were examined. Follow-up information was available in 64 cases and an eventual clinical diagnosis was made in 54 (84%) of these; the commonest diagnoses were rosacea (26%), chronic discoid lupus erythematosus (24%) and seborrheic or unclassified dermatitis (17%). Histological differences were seen in the original biopsies of these three diagnostic categories, although none was predictive. We conclude that clinical follow-up leads to the diagnosis of most facial rashes initially showing "non-specific" histology.

journal_name

J Cutan Pathol

journal_title

Journal of cutaneous pathology

authors

Rhodes LE,Parslew RA,Ashworth J

doi

10.1111/j.1600-0560.1995.tb01400.x

subject

Has Abstract

pub_date

1995-04-01 00:00:00

pages

160-3

issue

2

eissn

0303-6987

issn

1600-0560

journal_volume

22

pub_type

杂志文章

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