Expression of stromal cell markers in distinct compartments of human skin cancers.

abstract：:Galli-Galli disease (GGD) and Dowling-Degos disease (DDD) are inherited skin diseases with variable progressive course. They are of benign and harmless behaviour but aesthetically annoying. They are subsumed within the group of reticulate pigmented disorders of the skin to which, additionally, Kitamura's and Haber's d...

journal_title：Journal of cutaneous pathology

authors： Müller CS,Pföhler C,Tilgen W

更新日期：2009-01-01 00:00:00

abstract：:Biologic therapies targeting tumor necrosis factor (TNF)-alpha have become a mainstay in the management of a number of autoimmune diseases. We report a series of adverse skin eruptions in six patients (four females, two males, age: 21-58 years, mean: 39) receiving 4 months to 10 years (mean 3.1 years) of anti-TNF-alph...

journal_title：Journal of cutaneous pathology

authors： Hawryluk EB,Linskey KR,Duncan LM,Nazarian RM

更新日期：2012-05-01 00:00:00

abstract：:Chronic lymphocytic leukemia (CLL/SLL) is the most common leukemia in the western world and its cutaneous dissemination a very uncommon phenomenon. Lymphomatoid papulosis (LyP) is a CD30+ lymphoproliferative disorder characterized by chronic, recurrent and self healing skin lesions. Up to 20% of patients with LyP have...

journal_title：Journal of cutaneous pathology

authors： Hibler J,Salavaggione AL,Martin A,Gru AA

更新日期：2015-04-01 00:00:00

abstract：:This report documents the case of a 64-year-old African-American female with new end-stage renal disease (ESRD), diagnosed with systemic lupus erythematosus (SLE) on renal biopsy and serologies including a positive ANA (>1:2560), positive anti-Sm antibodies, low titer anti-RNP antibodies, high titer anti-Ro antibodies...

journal_title：Journal of cutaneous pathology

authors： Goyal A,Jain M,Rehberg K,Goodman W,Gertner E

更新日期：2019-09-01 00:00:00

abstract：:The so-called perivascular epithelioid cell neoplasm (PEComa) family includes angiomyolipoma, clear cell 'sugar' tumor (CCST), lymphangioleiomyomatosis, and clear cell myomelanocytic tumor (CCMMT). These rare tumors are characterized by the co-expression of melanocytic and muscle markers. They have been recognized in ...

journal_title：Journal of cutaneous pathology

authors： de Saint Aubain Somerhausen N,Gomez Galdon M,Bouffioux B,Courtin C,Theunis A,Vogeleer MN,Myant N

更新日期：2005-07-01 00:00:00

abstract：:Cutaneous syncytial myoepithelioma (CSM) is a recently recognized, histopathological variant of myoepithelial (ME) tumors of the skin. It is characterized by a syncytial arrangement of spindled, ovoid, and/or epithelioid cells forming a well-circumscribed, unencapsulated dermal nodule. There is a paucity of intervenin...

journal_title：Journal of cutaneous pathology

authors： MacKinnon WF,Carter MD,Bridge JA,Tremaine RD,Walsh NMG

更新日期：2019-06-01 00:00:00

abstract：:"Adenoma sebaceum of Pringle" (ASP) is a misnomer. The tumor is not an adenoma and is not derived from sebaceous glands. The lesion is characterized by dermal fibrosis and associated vascular proliferation and dilatation. Changes in contiguous sebaceous glands and other adnexal structures are merely secondary. Thus, "...

journal_title：Journal of cutaneous pathology

authors： Sanchez NP,Wick MR,Perry HO

更新日期：1981-12-01 00:00:00

abstract：BACKGROUND:Primary cutaneous apocrine cribriform carcinoma (PCACC) is a rare tumor, clinically appearing as a solitary nodule, mostly involving extremities of females and this lesion usually raises a differential diagnosis with metastatic cribriform carcinomas, especially breast cancer. OBJECTIVE:To study GATA3 expres...

journal_title：Journal of cutaneous pathology

authors： Llamas-Velasco M,Pérez-Gónzalez YC,Daudén E,Rütten A

更新日期：2018-05-01 00:00:00

abstract：:We describe a patient with thrombocytopenia-absent radius (TAR) syndrome, multisystemic Langerhans cell histiocytosis and multiple reticulohistiocytomas. A mutational study by massive sequencing identified the Val600Glu (V600E) BRAF mutation in the Langerhans cell histiocytosis lesions, but no molecular alterations we...

journal_title：Journal of cutaneous pathology

authors： Hipólito LN,Mendoza-Cembranos MD,Villaescusa MT,Jo-Velasco M,Requena L,Alegría-Landa V

更新日期：2019-08-01 00:00:00

abstract：:Agminated, or grouped Spitz nevi are a curious expression of nevomelanocytic growth; and represent an uncommon manifestation of these nevi. We encountered an example of agminated Spitz nevi present at birth, which showed progression and rapid growth over months. All showed histologic Spitz nevus features. Avidin-bioti...

journal_title：Journal of cutaneous pathology

authors： Palazzo JP,Duray PH

更新日期：1988-06-01 00:00:00

abstract：BACKGROUND:Erythroderma, defined as red skin covering most of the body surface often accompanied or followed by exfoliation, is the clinical manifestation of at least six different underlying etiologies with allergic or irritant contact dermatitis, atopic/asteotic dermatitis, pityriasis rubra pilaris (PRP), psoriasis, ...

journal_title：Journal of cutaneous pathology

authors： Cherny S,Mraz S,Su L,Harvell J,Kohler S

更新日期：2001-08-01 00:00:00

abstract：BACKGROUND:The histogenesis of extramammary Paget's disease (EMPD) is still controversial. Benign pagetoid cells of the nipple first described by Toker and the similar clear cells found in white maculopapules of clear cell papulosis (CCP) have been proposed to be potential precursor cells giving rise to EMPD and primar...

journal_title：Journal of cutaneous pathology

authors： Chen YH,Wong TW,Lee JY

更新日期：2001-02-01 00:00:00

abstract：:Imiquimod (AldaraTM), a Toll-like receptor 7 agonist (TLR7), is known for its unique properties of being an immune response modifier and stimulator. Upon topical application, this TLR7 agonist triggers a cell-mediated immune response predominantly expressed by dendritic cells and monocytes. Local skin irritation at th...

journal_title：Journal of cutaneous pathology

authors： Barr KL,Konia TH,Fung MA

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Ulceration and osteoclast-like giant cells are two pathological features uncommonly seen in dermatofibromas. To our knowledge, the presence of these features has not been previously described within the same lesion. METHODS:We report the clinical, histopathological and immunohistochemical findings of a 38-y...

journal_title：Journal of cutaneous pathology

authors： González-Vilas D,García-Gavín J,Ginarte M,Rodríguez-Blanco I,Toribio J

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Co-lesional acquired immunodeficiency syndrome-associated cutaneous Kaposi sarcoma (AIDS-KS) and Mycobacterium tuberculosis-associated granulomatous inflammation are undocumented. METHOD:Retrospective appraisal of skin biopsies with co-lesional AIDS-KS and microscopic tuberculosis (TB). RESULTS:Sixteen bio...

journal_title：Journal of cutaneous pathology

authors： Ramdial PK,Sing Y,Subrayan S,Calonje E,Aboobaker J,Sydney C,Sookdeo D,Ramburan A,Madiba TE

更新日期：2010-08-01 00:00:00

abstract：:Desmoplastic melanoma can be difficult to distinguish from desmoplastic melanocytic nevi both clinically and histopathologically. Several attempts have been made to explore the use of ancillary studies to facilitate this distinction. Prior work has suggested that immunohistochemical expression of p16 could help distin...

journal_title：Journal of cutaneous pathology

authors： Blokhin E,Pulitzer M,Busam KJ

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Apocrine carcinomas are rare, the immunohistochemical characterizations that are incomplete. The purpose of this study was to determine the immunohistochemical characteristics of mucin core proteins and keratins in apocrine carcinoma, extramammary Paget's disease (EMPD) and apocrine nevus. METHODS:We report...

journal_title：Journal of cutaneous pathology

authors： Miyamoto T,Inoue S,Adachi K,Takada R

更新日期：2009-05-01 00:00:00

abstract：:With the exception of skin cancer, prostatic adenocarcinoma represents the most common cancer among men in the United States and the second most common cause of cancer mortality. Mortality is often associated with metastatic disease, which in the case of prostatic adenocarcinoma typically involves bones and only rarel...

journal_title：Journal of cutaneous pathology

authors： Rattanasirivilai A,Kurban A,Lenzy YM,Yaar R

更新日期：2011-06-01 00:00:00

abstract：:Angioimmunoblastic T-cell lymphoma (AITL) is an aggressive form of peripheral T-cell lymphoma, characterized by systemic symptoms, diffuse lymphadenopathy, hepatosplenomegaly and immunodysregulation. Half of AITL is associated with cutaneous symptoms, but only few cases with bullous eruption have been described. Assoc...

journal_title：Journal of cutaneous pathology

authors： Colmant C,Camboni A,Dekeuleneer V,Marot L,Dachelet C,Baeck M

更新日期：2020-03-01 00:00:00

abstract：:We report a first case of ossifying fibromyxoid tumor of soft parts of the back, a 10 x 9.5 x 6 cm well-circumscribed elevated subcutaneous tumor demarcated by an incomplete fibrous capsule with bone formation at its base. The tumor was composed of both myxomatous areas with spindle tumor cells and pseudoalveolar stru...

journal_title：Journal of cutaneous pathology

authors： Nakayama F,Kuwahara T

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:Cryptococcosis and alternariosis are rare opportunistic infections often observed in immunocompromised patients. Because Cryptococcus and Alternaria are ubiquitous fungi found in soil, the presence of fungi in the dermis has to be observed on histological examination to confirm a real cutaneous, invasive, in...

journal_title：Journal of cutaneous pathology

authors： Courville P,Favennec L,Viacroze C,Barrel A,Young P,Abboud P,Thomine E,Metayer J,Nouvet G

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:The migration of circulating monocytes into the dermis is considered to be essential for both the initiation and the progression of xanthoma. The contribution of vascular endothelial cells to the migration process is unclear. METHODS:Twenty cases of xanthelasma and six cases of tuberous xanthoma lesions wer...

journal_title：Journal of cutaneous pathology

authors： Matsumoto M,Kunimitsu S,Wada K,Ikeda M,Yokogawa M,Keyama A,Kodama H

更新日期：2007-10-01 00:00:00

abstract：:Claudins are a family of transmembrane proteins involved in cell-to-cell adhesion and are believed to be the main component of tight junctions. Recent studies have suggested that some metastatic solid tumors lack claudin expression. It is unknown whether claudins play a role in cutaneous melanoma. Immunohistochemical ...

journal_title：Journal of cutaneous pathology

authors： Cohn ML,Goncharuk VN,Diwan AH,Zhang PS,Shen SS,Prieto VG

更新日期：2005-09-01 00:00:00

abstract：:We report a hitherto undescribed unusual CD30+ clonal T-cell proliferation in a 46-year-old man with the lymphocytic variant of hypereosinophilic syndrome with a 17-year history of pruritus, generalized persistent papulonodular skin lesions and peripheral blood hypereosinophilia. A skin biopsy showed an eosinophil-ric...

journal_title：Journal of cutaneous pathology

authors： Kempf W,Kazakov DV,Szep Z,Vanecek T

更新日期：2015-02-01 00:00:00

abstract：:Dermal non-neural granular cell tumor (NNGCT) was first described in 1991 as an S100-negative polypoid non-melanocytic tumor. Although originally introduced in the literature as a primary cutaneous tumor, it was later emphasized that such qualification could not be held until the line of differentiation was clarified....

journal_title：Journal of cutaneous pathology

authors： Fernandez-Flores A,Cassarino DS,Riveiro-Falkenbach E,Rodriguez-Peralto JL,Fernandez-Figueras MT,Monteagudo C

更新日期：2017-06-01 00:00:00

abstract：:Neutrophilic panniculitis is an infrequent entity, considered by most authors as part of the 'neutrophilic dermatosis' spectrum. Few cases have been reported to be related with granulocyte colony-stimulating factor (G-CSF); we report a case of neutrophilic panniculitis and Sweet's syndrome lesions related with pegfilg...

journal_title：Journal of cutaneous pathology

authors： Llamas-Velasco M,García-Martín P,Sánchez-Pérez J,Fraga J,García-Diez A

更新日期：2013-01-01 00:00:00

abstract：:A case study of sinus histiocytosis of Rosai-Dorfman (SH) clinically limited to the skin is presented with immunohistochemical study of the infiltrate, in both paraffin and cryostat sections. Factor XIIIa, a dendrocyte marker, was demonstrated in the cytoplasm of histiocytes. This feature had not been previously repor...

journal_title：Journal of cutaneous pathology

authors： Perrin C,Michiels JF,Lacour JP,Chagnon A,Fuzibet JG

更新日期：1993-08-01 00:00:00

abstract：:A 60-year-old female and a 59-year-old male each presented with a solitary circumscribed patch of depressed skin of the right thenar palm and right sole, respectively. Both lesions were present for approximately 30 years without a history of trauma or other inciting incident. Histologically, the lesions showed a well-...

journal_title：Journal of cutaneous pathology

authors： Barry CI,Glusac EJ,Kashgarian M,Gwin K,McNiff JM

更新日期：2008-05-01 00:00:00

abstract：:A case of basal cell carcinoma with "monster cells" is reported. Clinically, the lesion presented as a red nodule on the forearm of a 58-year-old male. The histologic picture was striking, with large, "monstrous" nuclei scattered throughout a well defined nodule. Basal cell carcinoma with monster cells appears to repr...

journal_title：Journal of cutaneous pathology

authors： Elston DM,Bergfeld WF,Petroff N

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:The present study evaluates the signal transducer and activator of transcription-3 (STAT-3) expression and activation in actinic cheilitis (AC) and the relationship of this protein with the degree of epithelial dysplasia. METHODS:Twenty-five cases of AC were analyzed. Normal lip mucosa was used as a control...

journal_title：Journal of cutaneous pathology

authors： Cury PR,Furuse C,de Araújo NS,de Araújo VC

更新日期：2007-08-01 00:00:00