Adenoma sebaceum of Pringle: a clinicopathologic review, with a discussion of related pathologic entities.

abstract：BACKGROUND:Podoconiosis is a familial geochemical dermatosis which is common in Ethiopia but relatively unknown in Europe/United States. It is related to exposure of bare feet to volcanic soil and presents with extensive bilateral lymphedema of legs and feet. Histopathological and immunohistochemical features of it hav...

journal_title：Journal of cutaneous pathology

authors： Wendemagegn E,Tirumalae R,Böer-Auer A

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Alpha-methylacyl-CoA racemase (AMACR), also known as P504S, is a protein that plays an important role in mitochondrial and peroxisomal beta-oxidation of branched-chain fatty acid and bile acid intermediates. AMACR has been established as a valuable diagnostic marker for prostate cancer and has recently been ...

journal_title：Journal of cutaneous pathology

authors： Halsey MA,Calder KB,Mathew R,Schlauder S,Morgan MB

更新日期：2010-04-01 00:00:00

abstract：:Medallion-like dermal dendrocyte hamartoma is a rare congenital lesion that is more commonly seen in females. It often presents at birth on the neck or upper trunk as a well-circumscribed, atrophic patch with wrinkling of the overlying skin. Clinically, the differential diagnosis includes atrophoderma, anetoderma, and...

journal_title：Journal of cutaneous pathology

authors： Porubsky CF,Combs A,Buckley C,Goodman MB

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Psoriasis vulgaris is a common chronic inflammatory dermatosis. Disorders in keratinocyte proliferation, differentiation, inflammation and immune dysregulation are the major factors implicated in the pathogenesis of psoriasis vulgaris. METHODS:The study was performed in skin specimens of 25 patients with ps...

journal_title：Journal of cutaneous pathology

authors： Doger FK,Dikicioglu E,Ergin F,Unal E,Sendur N,Uslu M

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Nestin is one of the intermediate filaments that are expressed in proliferating neural progenitor cells during development of the central nervous system (CNS) and peripheral nervous system. Postnatal re-expression of the protein occurs mainly under pathological conditions, including injury and neoplasia. In ...

journal_title：Journal of cutaneous pathology

authors： Brychtova S,Fiuraskova M,Hlobilková A,Brychta T,Hirnak J

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Myxoid liposarcoma typically presents as a deep-seated mass in the lower extremity of adults. Presentation as a primary subcutaneous tumor is rare. Here we discuss clinicopathologic characteristics of three such cases and their differential diagnosis to alert dermatopathologists to this unusual clinical pres...

journal_title：Journal of cutaneous pathology

authors： Buehler D,Marburger TB,Billings SD

更新日期：2014-12-01 00:00:00

abstract：:Since the first demonstration of skin antibodies in sera of pemphigus patients by IF (Beutner & Jordon 1964), the scope of skin diseases in which immunologic findings may be of interest has enormously enlarged and dermatology remains one of the leading clinical specialities applying IHC in both diagnosis and research....

journal_title：Journal of cutaneous pathology

authors： Thivolet J,Faure M

更新日期：1983-02-01 00:00:00

abstract：BACKGROUND:Fatty acid synthase (FAS), the key enzyme responsible for the synthesis of fatty acids, is weakly expressed in some normal human tissues. Recently, FAS has been demonstrated to be overexpressed in many non-neoplastic highly proliferative lesions and in aggressive carcinomas with poor outcome, including colon...

journal_title：Journal of cutaneous pathology

authors： Innocenzi D,Alò PL,Balzani A,Sebastiani V,Silipo V,La Torre G,Ricciardi G,Bosman C,Calvieri S

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Cutaneous manifestations of B-cell chronic lymphocytic leukemia (B-CLL) comprise a wide spectrum of clinicopathologic presentations. In some cases, onset of skin lesions is triggered by antigenic stimulation, and specific skin infiltrates at sites of previous herpes simplex or herpes zoster infection have be...

journal_title：Journal of cutaneous pathology

authors： Cerroni L,Höfler G,Bäck B,Wolf P,Maier G,Kerl H

更新日期：2002-03-01 00:00:00

abstract：:We reviewed the clinical, histologic, and immunofluorescence features of 20 patients with pemphigus and neoplasia and compared them with a control group of 17 patients with pemphigus without neoplasia. Patients with neoplasia were divided according to clinical, histologic, and immunofluorescence findings into those wi...

journal_title：Journal of cutaneous pathology

authors： Mehregan DR,Oursler JR,Leiferman KM,Muller SA,Anhalt GJ,Peters MS

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:The Fli-1 transcription factor functions in cellular proliferation and tumorigenesis. Its role in various neoplasms and its presence in lymphocytes suggest a link between Fli-1 dysregulation and the pathogenesis of mycosis fungoides (MF). In this study, we further elucidate this possible link. METHODS:Secti...

journal_title：Journal of cutaneous pathology

authors： Quick CM,Smoller BR,Hiatt KM

更新日期：2006-09-01 00:00:00

abstract：:We present a case of a 64-year-old man with refractory acute myeloid leukemia and trisomy 8 who developed leukemia cutis. Interphase fluorescence in situ hybridization (FISH) was performed on a paraffin-embedded skin section. FISH confirmed a population of cells with trisomy 8 in the blastic infiltrates involving the ...

journal_title：Journal of cutaneous pathology

authors： Shvartsbeyn M,Meehan SM,Gu P,Nierodzik ML,Perle MA

更新日期：2012-11-01 00:00:00

abstract：:Extraskeletal Ewing's sarcoma has been recognized as being histologically indistinguishable from Ewing's sarcoma of bone. Although the occurrence of extraosseous Ewing's sarcoma in deep soft tissues has been well described, such cutaneous lesions are rare. We report the clinical history, histopathologic findings, and ...

journal_title：Journal of cutaneous pathology

authors： Peters MS,Reiman HM,Muller SA

更新日期：1985-12-01 00:00:00

abstract：BACKGROUND:Hypertrophic lichen planus (LP) is a variant of LP favoring the lower extremities and showing prominent epidermal hyperplasia and hyperorthokeratosis. Contrary to dogma that eosinophils are rare in LP and variants, we noticed that some cases of hypertrophic LP have eosinophils in the absence of drug history....

journal_title：Journal of cutaneous pathology

authors： Alomari A,McNiff JM

更新日期：2014-04-01 00:00:00

abstract：:Until recently the number of patients with syphilis has been diminishing. Although that trend has reversed cases of tertiary syphilis are rare and often difficult to diagnose as a substantial number of patients will have a negative rapid plasma reagin. Histologically, cutaneous lesions in late stage syphilis exist in ...

journal_title：Journal of cutaneous pathology

authors： Boyd AS

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Expression of programmed death ligand 1 (PD-L1) by cutaneous squamous cell carcinomas has been shown to correlate with advanced disease and risk of metastasis. Lymphocyte activation gene 3 (LAG-3, or CD223) is an inhibitory receptor that interacts with the PD-L1 axis, which has been shown to be a marker of i...

journal_title：Journal of cutaneous pathology

authors： Wu S,Slater NA,Sayed CJ,Googe PB

更新日期：2020-10-01 00:00:00

abstract：:We report a 20-year-old male patient with an atypical Spitz tumor, located in the dorsal aspect of his left hand, and a positive sentinel axillary lymph node. After lymphadenectomy, 1 of 23 non-sentinel lymph nodes excised was found to contain small multiple deposits of large spindle atypical melanocytes. Reviewing th...

journal_title：Journal of cutaneous pathology

authors： Urso C,Borgognoni L,Doria M,Tinacci G,Zini E

更新日期：2009-05-01 00:00:00

abstract：:Pigmented extramammary Paget disease (PEMPD) is a rare intraepithelial carcinoma which can clinically resemble other pigmented neoplasms. Similarities to melanoma on dermoscopy, histopathology, and reflectance confocal microscopy (RCM) increase the risk of misdiagnosis and, consequently, mismanagement. Here, we descri...

journal_title：Journal of cutaneous pathology

authors： Chuchvara N,Reilly C,Haroon A,Wassef C,Maghari A,Rao B

更新日期：2020-12-01 00:00:00

abstract：:A 46-year-old man had a cystic mass on the right side of his scalp. Histological examination revealed a cystic dermal nodule composed of relatively circumscribed lobules of proliferating squamous epithelium, with atypical mitoses and dyskeratotic cells of invasive structure, which was diagnosed as proliferating tricho...

journal_title：Journal of cutaneous pathology

authors： Masui Y,Komine M,Kadono T,Ishiura N,Maekawa T,Ihn H,Kikuchi K,Tamaki K

更新日期：2008-10-01 00:00:00

abstract：:The expression and localization of connexin 43 (Cx43) were investigated in normal human epidermis, pilosebaceous apparatus, basal cell carcinoma, and squamous cell carcinoma by immunofluorescence as well as by immunoelectron microscopy. In the normal epidermis the immunofluorescence was weak in the basal layer, increa...

journal_title：Journal of cutaneous pathology

authors： Tada J,Hashimoto K

更新日期：1997-11-01 00:00:00

abstract：:We report a case of a 68-year-old man with cutaneous leiomyosarcoma of the penis. Leiomyosarcoma of the penis is an extremely rare neoplasm that usually presents in middle to old age, and to our knowledge only approximately 30 cases have been reported in the literature to date. This is an important diagnosis in the di...

journal_title：Journal of cutaneous pathology

authors： Cibull TL,Thomas AB,Badve S,Billings SD

更新日期：2008-06-01 00:00:00

abstract：:We studied the degenerative "ancient" changes in 19 cases of benign cutaneous schwannoma (BCS). Using conventional and immunohistochemical stains, we found (a) degenerative changes in 15 of 19 BCS; (b) prominent vascular abnormalities in 11 of 15 BCS; and (c) cytologic atypia in 15 of 19 BCS, without mitotic figures. ...

journal_title：Journal of cutaneous pathology

authors： Argenyi ZB,Balogh K,Abraham AA

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:Telomerase plays a role in the immortalization of cells and carcinogenesis. Previous studies have yielded conflicting results on whether human telomerase RNA (hTER) expression differs in nevi, atypical nevi and melanomas using polymerase chain reaction-based telomeric repeat amplification protocol or in situ...

journal_title：Journal of cutaneous pathology

authors： Fullen DR,Zhu W,Thomas D,Su LD

更新日期：2005-11-01 00:00:00

abstract：:We describe a case of syringocystadenoma papilliferum (SCAP) with a unique histopathology. A 50-year-old Japanese woman presented with a pedunculated tumor in the pubic region. Histopathological examination showed that the tumor was composed of basaloid cell proliferation interconnecting from the epidermis to the derm...

journal_title：Journal of cutaneous pathology

authors： Kishibe M,Iwasaki T,Takahashi I,Ishida-Yamamoto A

更新日期：2018-12-01 00:00:00

abstract：:This report deals with seven examples of an epithelial cyst for which we have found no proper designation in the classification of epithelial skin cysts. Clinically, the lesion is often hyperpigmented, located in mid-dermis and shows epidermoid keratinization. The cyst contains laminated keratin, many pigmented hair s...

journal_title：Journal of cutaneous pathology

authors： Mehregan AH,Medenica M

更新日期：1982-12-01 00:00:00

abstract：BACKGROUND:Carcinoma cuniculatum and verrucous carcinoma are both very well differentiated forms of squamous carcinoma and thus difficult to separate histologically from pseudocarcinomatous hyperplasia. The diagnosis of each often requires clinical-pathologic correlation. METHODS:We reviewed the literature on cases re...

journal_title：Journal of cutaneous pathology

authors： Kubik MJ,Rhatigan RM

更新日期：2012-12-01 00:00:00

abstract：:Dirofilaria repens (formerly Dirofilaria conjunctiva) is a natural parasite of the subcutaneous tissues of dogs, cats and wild carnivores in Europe, Africa and Asia. Microfilariae are transmitted to humans by various species of mosquito. An autochthonous case of subcutaneous dirofilariasis is reported in a Greek patie...

journal_title：Journal of cutaneous pathology

authors： Tzanetou K,Gasteratos S,Pantazopoulou A,Gogou C,Konidaris D,Fragia K

更新日期：2009-08-01 00:00:00

abstract：:Mycosis fungoides in palmoplantar localization (MFPP) is a rare variant of MF that is confined to the hands and feet. Patients commonly receive treatment over many years for suspected palmoplantar dermatitis before the diagnosis is made. Most MFPP patients remain at patch or plaque stage, and often respond to treatmen...

journal_title：Journal of cutaneous pathology

authors： Pham AK,Carter JB,Ratcliffe NR,Fuld AD,Lansigan F,Burnside NJ,Guill MA 3rd,Zug KA,Jarvis LA,LeBlanc RE

更新日期：2018-06-01 00:00:00

abstract：:Breast implant-associated anaplastic large cell lymphoma (ALCL) is a newly described clinical and pathologic entity that typically presents as seroma in the fibrous scar around the implant. Less frequently, it presents as a solid peri-implant mass, and there have been no reports to date of cutaneous lesions as the pre...

journal_title：Journal of cutaneous pathology

authors： Alcalá R,Llombart B,Lavernia J,Traves V,Guillén C,Sanmartín O

更新日期：2016-07-01 00:00:00

abstract：:Large cell acanthoma (LCA) is an epidermal neoplasm whose nature has been variously explained. Though frequently hyperpigmented, we describe for the first time an achromic case located on the dorsum of the right hand of a 83-year-old woman. This observation is largely inconsistent with one of the theories about the na...

journal_title：Journal of cutaneous pathology

authors： Ambrojo P,Aguilar A,Requena L,Sánchez Yus E

更新日期：1990-06-01 00:00:00