Histopathological and immunohistochemical features of nodular podoconiosis.

abstract：:We studied the degenerative "ancient" changes in 19 cases of benign cutaneous schwannoma (BCS). Using conventional and immunohistochemical stains, we found (a) degenerative changes in 15 of 19 BCS; (b) prominent vascular abnormalities in 11 of 15 BCS; and (c) cytologic atypia in 15 of 19 BCS, without mitotic figures. ...

journal_title：Journal of cutaneous pathology

authors： Argenyi ZB,Balogh K,Abraham AA

更新日期：1993-04-01 00:00:00

abstract：:Biopsies from a 5-year-old girl with dermatomyositis and universal calcinosis were studied histopathologically and by means of electron optical techniques. The dermis was infiltrated by fibroblasts, lymphocytes and plasma cells. In the lower part of the dermis, dense basophilic areas were present. In the vicinity of t...

journal_title：Journal of cutaneous pathology

authors： Nielsen AO,Johnson E,Hentzer B,Kobayasi T

更新日期：1979-12-01 00:00:00

abstract：:Study of 14 patients with prurigo nodularis revealed that clinically the lesions were multiple, verrucous, and discrete and were set in normal-appearing skin. Microscopically, the lesions showed a vascular acanthomatous mass. The dermal nerves showed a tendency toward hyperplasia in parallel with the epidermal and vas...

journal_title：Journal of cutaneous pathology

authors： Doyle JA,Connolly SM,Hunziker N,Winkelmann RK

更新日期：1979-10-01 00:00:00

abstract：:Mycosis fungoides (MF) is a rare type of non-Hodgkin's lymphoma affecting the skin. Because MF develops slowly over several years and may have a variety of clinical presentations, including itchy patches, plaques or tumors that may be confused with common benign conditions such as eczema and psoriasis, the disease pre...

journal_title：Journal of cutaneous pathology

authors： Reddy K,Bhawan J

更新日期：2007-07-01 00:00:00

abstract：:We report a rare case of multiple, co-exisitng verruciform xanthomas (VXs) of the anogenital region in the setting of cutaneous trauma. VX is a rare benign mucocutaneous neoplasm that typically presents as a solitary lesion with a predilection for the oral cavity, although extra-oral lesions have been reported involvi...

journal_title：Journal of cutaneous pathology

authors： Cumberland L,Dana A,Resh B,Fitzpatrick J,Goldenberg G

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Cicatricial forms of alopecia, including lichen planopilaris (LPP) and discoid lupus erythematosus (DLE), may present with overlapping clinical features. In such cases, histopathological examination may provide key information for resolving the differential diagnosis. Optimally, microscopical analysis for al...

journal_title：Journal of cutaneous pathology

authors： Nguyen JV,Hudacek K,Whitten JA,Rubin AI,Seykora JT

更新日期：2011-05-01 00:00:00

abstract：:Clear cell atypical fibroxanthoma (CCAFX) is a rare variant of atypical fibroxanthoma (AFX), a pleomorphic dermal tumour associated with a good prognosis. A 67-year-old man presented with a rapidly growing nodule on the ear, which had appeared over a 2-week period. Sections showed an ulcerated nodule composed of pleom...

journal_title：Journal of cutaneous pathology

authors： Murali R,Palfreeman S

更新日期：2006-05-01 00:00:00

abstract：:The characteristic histologic change seen at 2 h in the Rumpel-Leede (Hess) test is, in addition to focal hemorrhage in the upper dermis, a perivascular lymphocyte infiltrate with focal areas of lymphocytic epidermal invasion. The histologic findings, even with the liquefaction degeneration, are similar to those of pu...

journal_title：Journal of cutaneous pathology

authors： Duncan SC,Winkelmann RK

更新日期：1979-02-01 00:00:00

abstract：:The majority of findings in relation to warts have been passed on from one textbook to the other since the end of the last century. More recent studies have been carried out with the electron microscope. But information is lacking as to histology, histochemistry, examination with the phase-contrast microscope, with th...

journal_title：Journal of cutaneous pathology

authors： Steigleder GK

更新日期：1978-04-01 00:00:00

abstract：BACKGROUND:Cutaneous leishmaniasis displays considerable variation in its histopathological and clinical presentation. Clinically, it progresses from a papule into a painless ulcerated and crusted nodule/papule. Microscopically, it progresses from sheets of amastigote-filled histiocytes to granulomatous inflammation. ...

journal_title：Journal of cutaneous pathology

authors： Saab J,Fedda F,Khattab R,Yahya L,Loya A,Satti M,Kibbi AG,Houreih MA,Raslan W,El-Sabban M,Khalifeh I

更新日期：2012-02-01 00:00:00

abstract：:Cutaneous lesions of lupus erythematosus (LE) show a broad spectrum of clinicopathologic features. Histopathologically, besides typical patterns such as interface dermatitis, perivascular lymphocytic infiltrate and dermal mucin deposits, an involvement of the eccrine structures, especially the acrosyringium, may be ob...

journal_title：Journal of cutaneous pathology

authors： Fried I,Wiesner T,Cerroni L

更新日期：2010-01-01 00:00:00

abstract：:A giant cell fibroblastoma (GCF) presented in the subcutis of the breast in a 13-month-old girl which recurred 6 years later as a dermal and subcutaneous neoplasm whose patterns were in part GCF and spindle cells with a storiform configuration resembling dermatofibrosarcoma protuberans (DFSP). The issue remains unsett...

journal_title：Journal of cutaneous pathology

authors： Perry DA,Schultz LR,Dehner LP

更新日期：1993-10-01 00:00:00

abstract：:Folliculo-sebaceous hamartomas comprise a series of entities whose boundaries are imprecise. We present the clinical case of a folliculo-sebaceous cystic hamartoma of genital localization where the diagnosis was established based on the epithelial proliferation, but mostly, on the characteristic stroma. Because this l...

journal_title：Journal of cutaneous pathology

authors： Alegría-Landa V,Jo-Velasco M,Prieto-Torres L,Requena L

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Becker nevus (BN) is a unilateral, hairy, pigmented cutaneous hamartoma that frequently appears in adolescence. Several features of BN suggest that increased androgen sensitivity plays a role in its pathogenesis. There have been only a few studies of histopathologic and immunohistochemical characteristics of...

journal_title：Journal of cutaneous pathology

authors： Kim YJ,Han JH,Kang HY,Lee ES,Kim YC

更新日期：2008-12-01 00:00:00

abstract：:Confocal laser scanning microscopy (CLSM) is a new optical microscopic technique, which offers significant advantages over conventional microscopy. CLSM is microscopy of optical sections. Light, which is emitted from regions other than the focal plane, is cut off by introducing a diaphragm in the beam path. The result...

journal_title：Journal of cutaneous pathology

authors： Fink-Puches R,Hofmann-Wellenhof R,Smolle J,Kerl H

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND:Co-lesional acquired immunodeficiency syndrome-associated cutaneous Kaposi sarcoma (AIDS-KS) and Mycobacterium tuberculosis-associated granulomatous inflammation are undocumented. METHOD:Retrospective appraisal of skin biopsies with co-lesional AIDS-KS and microscopic tuberculosis (TB). RESULTS:Sixteen bio...

journal_title：Journal of cutaneous pathology

authors： Ramdial PK,Sing Y,Subrayan S,Calonje E,Aboobaker J,Sydney C,Sookdeo D,Ramburan A,Madiba TE

更新日期：2010-08-01 00:00:00

abstract：:Merkel cell carcinoma is occasionally associated with other types of cutaneous malignancies including squamous cell carcinoma, basal cell carcinoma and lentigo maligna. We report a case of Merkel cell carcinoma co-existent with sebaceous carcinoma in the right upper eyelid of a 61-year-old Japanese man. Histopathologi...

journal_title：Journal of cutaneous pathology

authors： Tanahashi J,Kashima K,Daa T,Yada N,Fujiwara S,Yokoyama S

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:The use of immunohistochemical (IHC) stains in dermatopathology is commonplace; however, little is known regarding utilization trends in melanoma diagnosis. Current Medicare local coverage determinations (LCDs) state that most pigmented lesions, including melanoma, can be diagnosed using H&E alone. METHODS:...

journal_title：Journal of cutaneous pathology

authors： Dinehart MS,Dinehart SM,Sukpraprut-Braaten S,High WA

更新日期：2020-05-01 00:00:00

abstract：:We encountered a patient who complained of many small papules on the neck, shoulders, upper chest and upper back. Biopsy specimens showed complete loss of elastic fibers in the upper dermis including papillary dermis, whereas those of the mid dermis were intact. Electron microscopy revealed that assembly of component ...

journal_title：Journal of cutaneous pathology

authors： Hashimoto K,Tye MJ

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:The diagnosis of 'cellular dermal nodule in melanocytic nevi' is challenging, as it can simulate invasive and tumorigenic melanoma. Because cellular nodules are presumed benign, it is essential to differentiate them from true malignant melanoma arising within a nevus, which portends a poor prognosis. Althoug...

journal_title：Journal of cutaneous pathology

authors： Xu X,Bellucci KS,Elenitsas R,Elder DE

更新日期：2004-02-01 00:00:00

abstract：:Pilomatrix (pilomatrical) carcinoma is a rare cutaneous adnexal tumor with matrical differentiation and recurrent and metastatic potential. Sarcomatoid pilomatrix carcinoma is a rare variant which shows a sarcomatoid component intermingling with the epithelial one. There are only 4 cases previously published. We prese...

journal_title：Journal of cutaneous pathology

authors： Fernandez-Flores A,Cassarino DS

更新日期：2018-07-01 00:00:00

abstract：:Herpetic syringitis has been described as a rare manifestation of herpes virus infection in patients with an immunodeficiency, usually secondary to human immunodeficiency virus (HIV) infection. Eccrine squamous syringometaplasia (ESS) is an infrequent alteration of the eccrine duct epithelium reported in association w...

journal_title：Journal of cutaneous pathology

authors： Muñoz E,Valks R,Fernández-Herrera J,Fraga J

更新日期：1997-08-01 00:00:00

abstract：:Desmoplastic melanoma can be difficult to distinguish from desmoplastic melanocytic nevi both clinically and histopathologically. Several attempts have been made to explore the use of ancillary studies to facilitate this distinction. Prior work has suggested that immunohistochemical expression of p16 could help distin...

journal_title：Journal of cutaneous pathology

authors： Blokhin E,Pulitzer M,Busam KJ

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Diagnosis of autoantibody- and immune complex-induced skin diseases is primarily based on direct immunofluorescence (DIF) microscopy. DIF staining is usually performed manually and, therefore, is labor intensive. The quality of immunohistochemical results considerably depends on the experience of the person ...

journal_title：Journal of cutaneous pathology

authors： Lemcke S,Sokolowski S,Rieckhoff N,Buschtez M,Kaffka C,Winter-Keil A,Schaller C,Rottmann N,Sadik CD,Stöcker W,Zillikens D,Schmidt E

更新日期：2016-03-01 00:00:00

abstract：:Two cases of juvenile elastoma (nevus elasticus in disseminated tumors) were histologically and ultrastructurally investigated. The predominant components of this disseminated dysembryoplasia are abnormal elastic fibers. Both cases showed numerous large elastic fibers with an abundant background matrix. The elastic mi...

journal_title：Journal of cutaneous pathology

authors： Ledoux-Corbusier M,Achten G,De Dobbeleer G

更新日期：1981-06-01 00:00:00

abstract：BACKGROUND:Ulceration and osteoclast-like giant cells are two pathological features uncommonly seen in dermatofibromas. To our knowledge, the presence of these features has not been previously described within the same lesion. METHODS:We report the clinical, histopathological and immunohistochemical findings of a 38-y...

journal_title：Journal of cutaneous pathology

authors： González-Vilas D,García-Gavín J,Ginarte M,Rodríguez-Blanco I,Toribio J

更新日期：2009-10-01 00:00:00

abstract：:Two elderly patients with unusual hair-follicle tumors of the face are reported. The lesions showed some histologic resemblance to pilomatrixomas but differed by the presence at the advancing edge of cytologically-atypical cells without the usual shadow cell transformation and maturation of pilomatrixomas. The term ma...

journal_title：Journal of cutaneous pathology

authors： Weedon D,Bell J,Mayze J

更新日期：1980-02-01 00:00:00

abstract：BACKGROUND:Pemphigoides gestationis (PG) is a blistering disorder of pregnancy caused by antibodies against basement membrane proteins. They are directed against the 180 kD bullous pemphigoid antigen (BPAg2), towards the epitopes within the NC 16A domain. There are many similarities between pemphigoid gestationis and b...

journal_title：Journal of cutaneous pathology

authors： Patton T,Plunkett RW,Beutner EH,Deng JS,Jukic DM

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Merkel cell carcinoma (MCC) is an aggressive neoplasm, which is often associated with Merkel cell polyomavirus (MCPyV). Programmed death-1 (PD-1) and its ligand PD-L1 are key players of the tumor microenvironment (TME). METHODS:Fourteen paraffin-embedded tissue samples of MCC were stratified by their MCPyV ...

journal_title：Journal of cutaneous pathology

authors： Mitteldorf C,Berisha A,Tronnier M,Pfaltz MC,Kempf W

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Chronic amastigote-negative cutaneous leishmaniasis (CL) is a diagnostic challenge, as the parasite load may be low, or absent in biopsy tissue sections. METHODS:A series of consecutive biopsy specimens, taken from 130 patients with a diagnosis of granulomatous dermatitis of unknown etiology, were reviewed....

journal_title：Journal of cutaneous pathology

authors： Tomasini C,Moneghini L,Barbui AM

更新日期：2017-06-01 00:00:00