Vascular endothelial cell distribution and adhesion molecule expression in xanthoma.

abstract：BACKGROUND:Infection with parvovirus B19 (B19) has been associated with connective tissue disease (CTD) stigmata, namely, a systemic lupus erythematosus (SLE)-like illness, seronegative polyarthritis resembling rheumatoid arthritis, and vasculitis. The dermatopathology and pathogenetic basis of such B19-associated CTD-...

journal_title：Journal of cutaneous pathology

authors： Crowson AN,Magro CM,Dawood MR

更新日期：2000-11-01 00:00:00

abstract：:Mucinous cutaneous adnexal tumors are an uncommon occurrence. We describe three cases of mucinous hidradenoma characterized by diffuse and prominent mucinous cell proliferation and discuss the relevant literature. The patients (two men and one woman) ranged in age from 32 to 72 years. The lesions were completely excis...

journal_title：Journal of cutaneous pathology

authors： Goh SG,Carr R,Dayrit JF,Calonje E

更新日期：2007-06-01 00:00:00

abstract：:Immunotherapies targeting cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) and the programmed cell death 1 (PD-1) receptor and its ligand (PD-L1) have showed significant therapeutic benefit in patients with clinically advanced solid malignancies, including melanoma. However, immune-related adverse events (irAE) ar...

journal_title：Journal of cutaneous pathology

authors： Trinidad C,Nelson KC,Glitza Oliva IC,Torres-Cabala CA,Nagarajan P,Tetzlaff MT,Ivan D,Hwu WJ,Prieto VG,Curry JL,Aung PP

更新日期：2018-07-01 00:00:00

abstract：:The skin biopsy specimens from six patients with primary mixed IgM-IgG cryoglobulinemia were examined by immunofluorescence, light and electron microscopy. The biopsy taken from the involved skin of one patient with leg ulcers revealed small blood vessel occlusions by cryoglobulin aggregates. Since a similar finding w...

journal_title：Journal of cutaneous pathology

authors： Berliner S,Weinberger A,Ben-Bassat M,Idesess C,Hazaz B,David M,Pinkhas J

更新日期：1982-04-01 00:00:00

abstract：BACKGROUND:To date, there has been no systematic investigation of the detailed histological features of prurigo nodularis (PN) in a large cohort of patients. METHODS:This retrospective study includes skin biopsies of 136 patients (63 males, 73 females; mean age: 58.38 years) with PN. RESULTS:Highly characteristic for...

journal_title：Journal of cutaneous pathology

authors： Weigelt N,Metze D,Ständer S

更新日期：2010-05-01 00:00:00

abstract：:Free-living amebae are ubiquitous in our environment, but rarely cause cutaneous infection. Balamuthia mandrillaris has a predilection for infecting skin of the central face. Infection may be restricted to the skin or associated with life-threatening central nervous system (CNS) involvement. We report a case of a 91-y...

journal_title：Journal of cutaneous pathology

authors： Chang OH,Liu F,Knopp E,Muehlenbachs A,Cope JR,Ali I,Thompson R,George E

更新日期：2016-10-01 00:00:00

abstract：:Keratoacanthoma (KA), an epithelial neoplasm occurring in sun-exposed skin of the elderly, is considered a well-differentiated form of conventional squamous cell carcinoma (SCC) that often follows a course of spontaneous regression. Distinguishing KA from conventional SCC or pseudocarcinomatous epithelial hyperplasia ...

journal_title：Journal of cutaneous pathology

authors： Shah K,Kazlouskaya V,Lal K,Molina D,Elston DM

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Some examples of Bowen disease lack the characteristic broad parakeratosis making their histopathologic diagnosis particularly difficult in small and incomplete biopsies. MATERIALS AND METHODS:The archives of our dermatopathology laboratory were searched for cases of Bowen disease with >75% orthokeratosis (...

journal_title：Journal of cutaneous pathology

authors： Idriss MH,Misri R,Böer-Auer A

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Carcinoma cuniculatum and verrucous carcinoma are both very well differentiated forms of squamous carcinoma and thus difficult to separate histologically from pseudocarcinomatous hyperplasia. The diagnosis of each often requires clinical-pathologic correlation. METHODS:We reviewed the literature on cases re...

journal_title：Journal of cutaneous pathology

authors： Kubik MJ,Rhatigan RM

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:During a clinical trial, we obtained 16 biopsies of skin eruptions induced by aspirin in patients with chronic idiopathic urticaria (CIU). In this setting, aspirin triggers skin eruptions through a well-established non-immunological mechanism involving the inhibition of cyclooxygenase type I. This presented ...

journal_title：Journal of cutaneous pathology

authors： Zembowicz A,Mastalerz L,Setkowicz M,Radziszewski W,Szczeklik A

更新日期：2004-04-01 00:00:00

abstract：:CD8+ T-cell lymphomas presenting in the skin are rare. We describe the clinical and histological features of 18 patients with CD8+ cutaneous T-cell tumors, which have been divided into four groups. Seven patients had precedent long histories of rashes, which progressively spread in a presentation similar to that of CD...

journal_title：Journal of cutaneous pathology

authors： Lu D,Patel KA,Duvic M,Jones D

更新日期：2002-09-01 00:00:00

abstract：:The expression of cytokeratins in 10 cases of clear cell hidradenoma, including 3 cases of solid cystic hidradenoma, were examined using 21 kinds of monoclonal antibodies. We divided them into three histologic patterns: massive nests with a few lumina (M nests), nests with some tubular lumina (L nests), and nests in s...

journal_title：Journal of cutaneous pathology

authors： Ohnishi T,Watanabe S

更新日期：1997-01-01 00:00:00

abstract：:Facial inflammatory dermatoses can be difficult to diagnose in their early stages; skin biopsy may help but often shows indeterminate features. The aims of our study were to identify patients presenting with a facial dermatosis requiring skin biopsy, in whom the initial histological features were classified as "non-sp...

journal_title：Journal of cutaneous pathology

authors： Rhodes LE,Parslew RA,Ashworth J

更新日期：1995-04-01 00:00:00

abstract：:A 60-year-old female and a 59-year-old male each presented with a solitary circumscribed patch of depressed skin of the right thenar palm and right sole, respectively. Both lesions were present for approximately 30 years without a history of trauma or other inciting incident. Histologically, the lesions showed a well-...

journal_title：Journal of cutaneous pathology

authors： Barry CI,Glusac EJ,Kashgarian M,Gwin K,McNiff JM

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Rare cases of a non-bullous neutrophilic dermatosis occurring in patients with lupus erythematosus (LE) have been reported, often as the presenting manifestation of the disease. METHODS:We reviewed hematoxylin and eosin-stained slides and obtained clinical information from four additional patients, two of w...

journal_title：Journal of cutaneous pathology

authors： Gleason BC,Zembowicz A,Granter SR

更新日期：2006-11-01 00:00:00

abstract：:This report deals with seven examples of an epithelial cyst for which we have found no proper designation in the classification of epithelial skin cysts. Clinically, the lesion is often hyperpigmented, located in mid-dermis and shows epidermoid keratinization. The cyst contains laminated keratin, many pigmented hair s...

journal_title：Journal of cutaneous pathology

authors： Mehregan AH,Medenica M

更新日期：1982-12-01 00:00:00

abstract：:Syndecan-1 is a cell surface proteoglycan predominantly expressed on the surface of adult epithelial cells, and is normally present in all epidermal layers except for the most superficial terminally differentiated cells. Syndecan-1 mediates cell-cell and cell-extracellular matrix adhesion, thereby influencing cell mor...

journal_title：Journal of cutaneous pathology

authors： Bayer-Garner IB,Sanderson RD,Smoller BR

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:Hobnail hemangioma (targetoid hemosiderotic hemangioma) is a small benign vascular tumor of the superficial and mid-dermis. In contrast to its well-characterized histology, it has been unclear whether this tumor arises from blood vessel endothelial cells (BECs) or lymphatic vessel endothelial cells (LECs). ...

journal_title：Journal of cutaneous pathology

authors： Franke FE,Steger K,Marks A,Kutzner H,Mentzel T

更新日期：2004-05-01 00:00:00

abstract：:We report three new cases of neutrophilic eccrine hidradenitis associated with induction chemotherapy which resolves two major points. First, because two of our patients had testicular carcinoma; this firmly establishes that NEH is not exclusively seen in patients with acute myelogenous leukemia or Hodgkin's lymphoma ...

journal_title：Journal of cutaneous pathology

authors： Fitzpatrick JE,Bennion SD,Reed OM,Wilson T,Reddy VV,Golitz L

更新日期：1987-10-01 00:00:00

abstract：:The main histopathological features in the cutaneous lesions of Churg-Strauss syndrome (CSS) are dermal leukocytoclastic vasculitis with a variable eosinophilic infiltrate and non-vasculitic tissue eosinophilia with granuloma formation. This wide histopathological spectrum may account for the various skin manifestatio...

journal_title：Journal of cutaneous pathology

authors： Ishibashi M,Kudo S,Yamamoto K,Shimai N,Chen KR

更新日期：2011-03-01 00:00:00

abstract：:Clear cell atypical fibroxanthoma (CCAFX) is a rare variant of atypical fibroxanthoma (AFX), a pleomorphic dermal tumour associated with a good prognosis. A 67-year-old man presented with a rapidly growing nodule on the ear, which had appeared over a 2-week period. Sections showed an ulcerated nodule composed of pleom...

journal_title：Journal of cutaneous pathology

authors： Murali R,Palfreeman S

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Although a range of cytomegalovirus (CMV)-induced cutaneous manifestations is described in AIDS patients, skin involvement in immunocompromised patients is rare, and intraneural CMV inclusions or CMV neuritis has not been documented in skin biopsies. METHODS AND RESULTS:Cutaneous biopsies of CMV lesions wer...

journal_title：Journal of cutaneous pathology

authors： Ramdial PK,Dlova NC,Sydney C

更新日期：2002-08-01 00:00:00

abstract：:The dermatological disorders associated with monoclonal gammopathies are clinically heterogeneous and may be divided into four groups with distinctive pathogenetic mechanisms (a) specific (infiltrative) disorders including primary and secondary cutaneous plasmacytoma and cutaneous lymphoplasmacytic infiltration of Wal...

journal_title：Journal of cutaneous pathology

authors： Rongioletti F,Patterson JW,Rebora A

更新日期：2008-08-01 00:00:00

abstract：:The rare presentation of choriocarcinoma as a cutaneous metastasis in a 23-year-old male is reported. Histological and immunohistochemical analysis of the biopsy material demonstrated two distinct cell populations, syncytiotrophoblasts and cytotrophoblasts, with syncytiotrophoblasts strongly positive for human chorion...

journal_title：Journal of cutaneous pathology

authors： Chhieng DC,Jennings TA,Slominski A,Mihm MC Jr

更新日期：1995-08-01 00:00:00

abstract：:The advent of immunoperoxidase technique on paraffin embedded tissue has identified a number of shared immunologic markers present in various lymphoproliferative cutaneous disorders. Two such disorders are the recently described primary cutaneous CD30-positive anaplastic large cell lymphoma (ALCL) and lymphomatoid pap...

journal_title：Journal of cutaneous pathology

authors： Tomaszewski MM,Lupton GP,Krishnan J,May DL

更新日期：1995-08-01 00:00:00

abstract：:Two cases of juvenile elastoma (nevus elasticus in disseminated tumors) were histologically and ultrastructurally investigated. The predominant components of this disseminated dysembryoplasia are abnormal elastic fibers. Both cases showed numerous large elastic fibers with an abundant background matrix. The elastic mi...

journal_title：Journal of cutaneous pathology

authors： Ledoux-Corbusier M,Achten G,De Dobbeleer G

更新日期：1981-06-01 00:00:00

abstract：:Extravasation of doxorubicin in skin and soft tissue causes necrosis and ulceration. These ulcers form slowly and heal with great difficulty. The cause of ulceration is not known. Histologic changes in two patients suggest that an exaggeration of interface dermatitis like epidermal changes may be responsible for epide...

journal_title：Journal of cutaneous pathology

authors： Bhawan J,Petry J,Rybak ME

更新日期：1989-06-01 00:00:00

abstract：:Epidermal Langerhans cells (LC) from skin of clinically normal appearance in psoriatics were studied electron microscopically and compared with LC from the skin of healthy volunteers and from those with other dermatoses. Results show that LC from psoriatics display partly distinct cytoplasmic alterations. Moreover, ab...

journal_title：Journal of cutaneous pathology

authors： Klug H,Sönnichsen N

更新日期：1988-12-01 00:00:00

abstract：BACKGROUND:Mucocutaneous depositions of various metals such as silver, lead, gold, arsenic, mercury, iron, and bismuth have been previously published. Heavy metal deposition typically occurs in the setting of either prolonged topical application to intact skin, topical application to eroded or ulcerated skin, as a resu...

journal_title：Journal of cutaneous pathology

authors： Greenberg JE,Lynn M,Kirsner RS,Elgart GW,Hanly AJ

更新日期：2002-11-01 00:00:00

abstract：:The usual method for detecting spirochetes in tissue sections is the silver stain; however, they are often difficult to detect due to marked background staining commonly seen with this technique. In certain clinical settings, such as neurosyphilis, congenital syphilis, and immunosuppressive conditions including human ...

journal_title：Journal of cutaneous pathology

authors： Hoang MP,High WA,Molberg KH

更新日期：2004-10-01 00:00:00