Non-bullous neutrophilic dermatosis: an uncommon dermatologic manifestation in patients with lupus erythematosus.

abstract：:Recently, T-cell lymphoma localized to the subcutaneous tissue has been reported. We report the clinical, histologic, immunohistochemical, and molecular genetic findings in 6 patients who we believe had this peculiar T-cell lymphoma with its unique morphologic and clinical features. All patients presented with deep-se...

journal_title：Journal of cutaneous pathology

authors： Mehregan DA,Su WP,Kurtin PJ

更新日期：1994-04-01 00:00:00

abstract：:A case study of sinus histiocytosis of Rosai-Dorfman (SH) clinically limited to the skin is presented with immunohistochemical study of the infiltrate, in both paraffin and cryostat sections. Factor XIIIa, a dendrocyte marker, was demonstrated in the cytoplasm of histiocytes. This feature had not been previously repor...

journal_title：Journal of cutaneous pathology

authors： Perrin C,Michiels JF,Lacour JP,Chagnon A,Fuzibet JG

更新日期：1993-08-01 00:00:00

abstract：:"Adenoma sebaceum of Pringle" (ASP) is a misnomer. The tumor is not an adenoma and is not derived from sebaceous glands. The lesion is characterized by dermal fibrosis and associated vascular proliferation and dilatation. Changes in contiguous sebaceous glands and other adnexal structures are merely secondary. Thus, "...

journal_title：Journal of cutaneous pathology

authors： Sanchez NP,Wick MR,Perry HO

更新日期：1981-12-01 00:00:00

abstract：:Bullous pemphigoid (BP) antigen and alpha 6 integrin are hemidesmosome-associated glycoproteins of basal keratinocytes. In this work, the immunoreactivity of antibodies to BP and to alpha 6 in salt- or dispase-split human skin, and in 46 biopsy specimens of various genetic and autoimmune bullous dermatoses taken from ...

journal_title：Journal of cutaneous pathology

authors： Kanitakis J,Zambruno G,Vassileva S,Giannetti A,Thivolet J

更新日期：1992-10-01 00:00:00

abstract：:Langerhans' cell histiocytosis (LCH) may be associated with a wide range of neoplastic disorders. However, the combination of a LCH and a basal cell carcinoma (BCC) of the skin still represents a highly unusual condition. In this publication, we report the case of a 48-year-old woman who developed a localized LCH invo...

journal_title：Journal of cutaneous pathology

authors： Simonart T,Urbain F,Verdebout JM,Feoli F,Lespagnard L,Dargent JL

更新日期：2000-10-01 00:00:00

abstract：:CD8+ T-cell lymphomas presenting in the skin are rare. We describe the clinical and histological features of 18 patients with CD8+ cutaneous T-cell tumors, which have been divided into four groups. Seven patients had precedent long histories of rashes, which progressively spread in a presentation similar to that of CD...

journal_title：Journal of cutaneous pathology

authors： Lu D,Patel KA,Duvic M,Jones D

更新日期：2002-09-01 00:00:00

abstract：:Cutaneous lesions of lupus erythematosus (LE) show a broad spectrum of clinicopathologic features. Histopathologically, besides typical patterns such as interface dermatitis, perivascular lymphocytic infiltrate and dermal mucin deposits, an involvement of the eccrine structures, especially the acrosyringium, may be ob...

journal_title：Journal of cutaneous pathology

authors： Fried I,Wiesner T,Cerroni L

更新日期：2010-01-01 00:00:00

abstract：:The distribution of desmoglein, plakoglobin, E-cadherin, and beta-catenin in the peri-lesional and lesional skin of Hailey-Hailey disease, Darier's disease, and pemphigus vulgaris was examined by immunoelectron microscopy. In the peri-lesional skin, the immunolabeling of these desmosomal components was localized to de...

journal_title：Journal of cutaneous pathology

authors： Tada J,Hashimoto K

更新日期：1998-02-01 00:00:00

abstract：:Brooke-Spiegler syndrome represents an autosomal dominant disease characterized by the occurrence of multiple cylindromas, trichoepitheliomas and (sporadically) spiroadenomas. Patients with Brooke-Spiegler syndrome are also at risk of developing tumors of the major and minor salivary glands. Patients with Brooke-Spieg...

journal_title：Journal of cutaneous pathology

authors： Ponti G,Nasti S,Losi L,Pastorino L,Pollio A,Benassi L,Giudice S,Bertazzoni G,Veratti E,Azzoni P,Bianchi Scarrà G,Seidenari S

更新日期：2012-03-01 00:00:00

abstract：:Epithelioid cells with foamy cytoplasm (histiocytoid features) are typical histopathologic findings among benign and malignant histiocytic neoplasms such as xanthoma and atypical fibroxanthoma. However, these changes are unusual in melanoma, which is typically composed of nested and variably pigmented atypical epithel...

journal_title：Journal of cutaneous pathology

authors： Farah M,Nagarajan P,Torres-Cabala CA,Curry JL,Amaria RN,Wargo J,Tawbi H,Ivan D,Prieto VG,Tetzlaff MT,Aung PP

更新日期：2018-07-01 00:00:00

abstract：:Lichen aureus is a rare disease of unknown origin that is classified under the group of pigmented purpuric dermatoses. Its most important differential diagnosis is both clinically and histologically mycosis fungoides, into which the disease can proceed in very rare cases. We describe an unusual multilocular lichen aur...

journal_title：Journal of cutaneous pathology

authors： Yazdi AS,Mayser P,Sander CA

更新日期：2008-10-01 00:00:00

abstract：:Galli-Galli disease (GGD) and Dowling-Degos disease (DDD) are inherited skin diseases with variable progressive course. They are of benign and harmless behaviour but aesthetically annoying. They are subsumed within the group of reticulate pigmented disorders of the skin to which, additionally, Kitamura's and Haber's d...

journal_title：Journal of cutaneous pathology

authors： Müller CS,Pföhler C,Tilgen W

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Nickel can induce cellular and nuclear damages responsible for chronic diseases, like allergic contact dermatitis (ACD). We previously showed that matrix metalloproteinase-2 (MMP-2) gene expression was induced by nickel in nontumorigenic human keratinocytes cell line (HaCat). OBJECTIVE:To investigate the si...

journal_title：Journal of cutaneous pathology

authors： Perfetto B,Lamberti M,Giuliano MT,Canozo N,Cammarota M,Baroni A

更新日期：2007-06-01 00:00:00

abstract：BACKGROUND:The Wnt-signaling pathway, involving beta-catenin, apc, and axin, plays a critical role in numerous developmental events. Alterations in the Wnt-signaling pathway have been detected in a wide variety of neoplasms. However, similar aberrations have not been described in Merkel cell carcinoma (MCC). The aim of...

journal_title：Journal of cutaneous pathology

authors： Liu S,Daa T,Kashima K,Kondoh Y,Yokoyama S

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Cutaneous tumor metastasis may be the first manifestation of cancer, but more often is a harbinger of advanced disease that portends an ominous prognosis. All skin accessions over the past 10 years from a large Veterans Administration (VA) hospital were reviewed. METHODS:Archived histories, glass slides, an...

journal_title：Journal of cutaneous pathology

authors： Saeed S,Keehn CA,Morgan MB

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Morphea (localized scleroderma) and eosinophilic fasciitis (EF) are rare fibrosing disorders which may present a diagnostic challenge. While histopathologic features are often distinct, in some cases there may be overlap. T-cells contribute to etiopathogenesis of both autoimmune conditions. We sought to dete...

journal_title：Journal of cutaneous pathology

authors： Moy AP,Maryamchik E,Nikolskaia OV,Nazarian RM

更新日期：2017-06-01 00:00:00

abstract：:The clinical, morphological and immunohistochemical features of 27 patients with anaplastic large cell lymphoma (ALCL) of CD30-positive type, with cutaneous lesions as the sole initial clinical manifestation, were analyzed. The neoplasm presented as solitary or multiple, usually ulcerated skin lesions, affecting predo...

journal_title：Journal of cutaneous pathology

authors： Krishnan J,Tomaszewski MM,Kao GF

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:Chronic graft-vs.-host disease (GVHD) is a severe and potentially fatal complication in patients after undergoing allogeneic stem cell transplant. This disease may be hard to diagnose as it has numerous cutaneous presentations. METHODS:We report four cases of patients seen at Stanford Hospital between Janua...

journal_title：Journal of cutaneous pathology

authors： Park JH,Lester L,Kim J,Kwong BY

更新日期：2016-03-01 00:00:00

abstract：:Fifteen halo nevi were stained for the presence of S100 protein by an unlabelled antibody peroxidase-antiperoxidase method. S100 protein was clearly identifiable within nevus cell nests in the inflammatory infiltrate. The presence of this substance helped to identify nevus cells in dense inflammatory infiltrates and c...

journal_title：Journal of cutaneous pathology

authors： Penneys NS,Mayoral F,Barnhill R,Ziegels-Weissman J,Nadji M

更新日期：1985-02-01 00:00:00

abstract：:An electron microscopic study was made of a patient with erythema elevatum diutinum, a rare variant of cutaneous leukocytoclastic vasculitis. Biopsies were obtained from early evolving and late fibroproliferative lesions. Early lesions showed vasculitis and a massive dermal infiltrate composed mainly of neutrophils, h...

journal_title：Journal of cutaneous pathology

authors： Lee AY,Nakagawa H,Nogita T,Ishibashi Y

更新日期：1989-08-01 00:00:00

abstract：:Oral mucosal melanoma (OMM) is an extremely rare malignancy, accounting for < 0.5% of all melanomas and all oral malignancies. The rarity of OMM, the heterogeneity in clinical and histopathologic appearances, and the paucity of molecular and genetic studies to date have limited our knowledge of the etiopathogenesis of...

journal_title：Journal of cutaneous pathology

authors： Kumar SK,Shuler CF,Sedghizadeh PP,Kalmar JR

更新日期：2008-04-01 00:00:00

abstract：:Malignant eccrine spiradenoma is an extremely rare skin tumor of sweat gland origin. In most cases, it arises in pre-existing benign eccrine spiradenoma. We report an additional case of malignant eccrine spiradenoma. The present case is of a 75-year-old man with malignant eccrine spiradenoma developed in the right sho...

journal_title：Journal of cutaneous pathology

authors： Ben Brahim E,Sfia M,Tangour M,Makhlouf R,Cribier B,Chatti S

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Hobnail hemangioma (targetoid hemosiderotic hemangioma) is a small benign vascular tumor of the superficial and mid-dermis. In contrast to its well-characterized histology, it has been unclear whether this tumor arises from blood vessel endothelial cells (BECs) or lymphatic vessel endothelial cells (LECs). ...

journal_title：Journal of cutaneous pathology

authors： Franke FE,Steger K,Marks A,Kutzner H,Mentzel T

更新日期：2004-05-01 00:00:00

abstract：:Acquired perforating calcific collagenosis (APCC), which is characterized by the calcification of dermal collagen fibers with subsequent transepidermal elimination and perforation, is an extremely rare entity. Thus far, it has only been reported in a patient with direct contact exposure to calcium chloride. Here, we r...

journal_title：Journal of cutaneous pathology

authors： Wang FY,Ng CY,Wu J,Kuo KL,Chang YY,Kuo TT

更新日期：2019-01-01 00:00:00

abstract：:Melanoma is known to show considerable variation in its histopathological presentation. In exceptional cases, heterologous or divergent differentiation (metaplastic melanoma) can be observed. We report a case of a 69-year-old man who was diagnosed with nodular melanoma on the right upper leg. One year later, the patie...

journal_title：Journal of cutaneous pathology

authors： Kilsdonk MJ,Romeijn TR,Kelder W,van Kempen LC,Diercks GF

更新日期：2020-12-01 00:00:00

abstract：:Systemic sclerosis (SSc) is an autoimmune systemic disease characterized by small vessel involvement that leads to tissue ischemia and fibroblast stimulation resulting in accumulation of collagen (fibrosis) in the skin and internal organs. Lipomembranous panniculitis is a peculiar type of fat necrosis and has been rep...

journal_title：Journal of cutaneous pathology

authors： Almeida MS,Lima SC,Carvalho LL,Almeida JV,Santos LG,Rolim JR,Rocha TE

更新日期：2010-11-01 00:00:00

abstract：:Early cutaneous Lyme disease, erythema migrans, may show different histopathologic patterns. The intent of this case series is to raise awareness of these findings to prevent misdiagnosis and keep this entity in the differential. Erythema migrans develops after a tick bite and subsequent infection with the spirochete,...

journal_title：Journal of cutaneous pathology

authors： Miraflor AP,Seidel GD,Perry AE,Castanedo-Tardan MP,Guill MA,Yan S

更新日期：2016-01-01 00:00:00

abstract：:Immunotherapies targeting cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) and the programmed cell death 1 (PD-1) receptor and its ligand (PD-L1) have showed significant therapeutic benefit in patients with clinically advanced solid malignancies, including melanoma. However, immune-related adverse events (irAE) ar...

journal_title：Journal of cutaneous pathology

authors： Trinidad C,Nelson KC,Glitza Oliva IC,Torres-Cabala CA,Nagarajan P,Tetzlaff MT,Ivan D,Hwu WJ,Prieto VG,Curry JL,Aung PP

更新日期：2018-07-01 00:00:00

abstract：:Herpetic syringitis has been described as a rare manifestation of herpes virus infection in patients with an immunodeficiency, usually secondary to human immunodeficiency virus (HIV) infection. Eccrine squamous syringometaplasia (ESS) is an infrequent alteration of the eccrine duct epithelium reported in association w...

journal_title：Journal of cutaneous pathology

authors： Muñoz E,Valks R,Fernández-Herrera J,Fraga J

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Bullous pemphigoid (BP) is the most common type of subepidermal bullous disease. Direct immunofluorescence (DIF) is the gold standard for diagnosis, but it requires a fresh tissue specimen. This study was conducted to evaluate the accuracy of using immunohistochemical (IHC) analysis for the detection of C4d ...

journal_title：Journal of cutaneous pathology

authors： Kamyab K,Abdolreza M,Ghanadan A,Mortazavi H,Nikoo A,Motavalli F,Nasimi M

更新日期：2019-10-01 00:00:00