Erythema elevatum diutinum: an ultrastructural case study.

Abstract:

:An electron microscopic study was made of a patient with erythema elevatum diutinum, a rare variant of cutaneous leukocytoclastic vasculitis. Biopsies were obtained from early evolving and late fibroproliferative lesions. Early lesions showed vasculitis and a massive dermal infiltrate composed mainly of neutrophils, histiocytes/macrophages and apparently increased Langerhans cells. Later lesions were characterized by a dense fibrosis with a proliferation of fibroblasts and myofibroblasts and a dermal infiltrate in which lymphocytes and histiocytes/macrophages predominated. Even in later lesions, dermal Langerhans cells were observed in great number. Langerhans cells may be involved in the evolution of this rare disease.

journal_name

J Cutan Pathol

authors

Lee AY,Nakagawa H,Nogita T,Ishibashi Y

doi

10.1111/j.1600-0560.1989.tb00043.x

subject

Has Abstract

pub_date

1989-08-01 00:00:00

pages

211-7

issue

4

eissn

0303-6987

issn

1600-0560

journal_volume

16

pub_type

杂志文章
  • Epidermotropic metastases from breast carcinoma showing different clinical and histopathological features on the trunk and on the scalp in a single patient.

    abstract::A 54-year-old female presented with the cutaneous metastases of the breast carcinoma that produced combination of pigmented zosteriform eruption on the trunk and eroded plaque on the scalp, 13 years after radical mastectomy. Histologically, zosteriform lesions displayed prominent infiltration of the epidermis in nesti...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1034/j.1600-0560.2003.00130.x

    authors: Brasanac D,Boricic I,Todorovic V

    更新日期:2003-11-01 00:00:00

  • A new locus for hereditary hypotrichosis simplex maps to chromosome 13q12.12 approximately 12.3 in a Chinese family.

    abstract:BACKGROUND:Hereditary hypotrichosis simplex (MIM 146520, HHS) is a rare form of nonsyndromic alopecia. The locus for autosomal dominant HHS was mapped to 18p11.32-p11.23 and 6p21.3, respectively, suggestive of genetic heterogeneity. AIM:To identify the disease-causing gene for a four-generation Chinese family with dom...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.1600-0560.2009.01415.x

    authors: Xu C,Zhang L,Chen N,Su B,Pan CM,Li JY,Zhang GW,Liu Z,Sheng Y,Song HD

    更新日期:2010-07-01 00:00:00

  • Colloid milium: a final degeneration product of actinic elastoid.

    abstract::Serum amyloid P component (SAP) is present not only in all types of cutaneous amyloidosis, but also in the normal dermal elastic fibers as well as abnormal elastic fibers, such as elastotic degeneration of elastic fibers in actinic keratosis. It was previously postulated that the colloid substance in colloid milium is...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.1600-0560.1985.tb01616.x

    authors: Hashimoto K,Black M

    更新日期:1985-04-01 00:00:00

  • The application of a monoclonal antibody to CD62L on paraffin-embedded tissue samples in the assessment of the cutaneous T-cell infiltrates.

    abstract:BACKGROUND:A reduction in the expression of the pan T-cell markers CD7 and CD62L supports an endogenous T-cell dyscrasia. Previously, clone availability for CD62L restricted its application to frozen tissue sections. MATERIALS AND METHODS:A nonavidin/biotin technique to examine CD3, CD62L, and CD7 in paraffin formalin...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.0303-6987.2005.00259.x

    authors: Magro CM,Sachdeva MP,Crowson AN,Barusevicius A,Baran PN,Kovatich AJ

    更新日期:2005-01-01 00:00:00

  • Broad range of adverse cutaneous eruptions in patients on TNF-alpha antagonists.

    abstract::Biologic therapies targeting tumor necrosis factor (TNF)-alpha have become a mainstay in the management of a number of autoimmune diseases. We report a series of adverse skin eruptions in six patients (four females, two males, age: 21-58 years, mean: 39) receiving 4 months to 10 years (mean 3.1 years) of anti-TNF-alph...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.1600-0560.2012.01894.x

    authors: Hawryluk EB,Linskey KR,Duncan LM,Nazarian RM

    更新日期:2012-05-01 00:00:00

  • Fibrous mastocytoma in a patient with generalized cutaneous mastocytosis.

    abstract::A 57-year-old woman with cutaneous mastocytosis of 23 years duration developed a hyperpigmented abdominal plaque composed of confluent indurated papules that enlarged for a period of 1 year to 12 x 8 cm. Biopsy showed dermal infiltration by closely packed spindle-shaped mast cells, fibroblasts, collagen, and scattered...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.1600-0560.1992.tb01354.x

    authors: Wood C,Sina B,Webster CG,Kurgansky D,Drachenberg CB,Reedy EA

    更新日期:1992-04-01 00:00:00

  • Sweet's syndrome with subcutaneous involvement associated with pegfilgrastim treatment: first reported case.

    abstract::Neutrophilic panniculitis is an infrequent entity, considered by most authors as part of the 'neutrophilic dermatosis' spectrum. Few cases have been reported to be related with granulocyte colony-stimulating factor (G-CSF); we report a case of neutrophilic panniculitis and Sweet's syndrome lesions related with pegfilg...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/cup.12042

    authors: Llamas-Velasco M,García-Martín P,Sánchez-Pérez J,Fraga J,García-Diez A

    更新日期:2013-01-01 00:00:00

  • Human papillomavirus-negative ileostomal chronic papillomatous dermatitis.

    abstract:BACKGROUND:Papillomatous stoma-related skin lesions may result from irritant reactions or infection with epidermodysplasia verruciformis human papillomavirus (HPV) types. METHODS:We report upon a papillomatous lesion at the ileostoma of a 63-year-old male with familial adenomatous polyposis and colorectal adenocarcino...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1046/j.0303-6987.2003.048.x

    authors: Williams CM,Wieland U,Rodning CB,Horenstein MG

    更新日期:2003-04-01 00:00:00

  • CD8-positive cutaneous lymphoproliferation associated with large granular lymphocyte leukemia in a patient with X-linked agammaglobulinemia.

    abstract::Patients with primary immunodeficiency are at increased risk for malignancy, especially hematologic neoplasms. This paper reports a unique case of a 47-year-old man with X-linked agammaglobulinemia who presented with progressive asymptomatic violaceous papules and plaques on his face, hands, and trunk for 1 year. Skin...

    journal_title:Journal of cutaneous pathology

    pub_type:

    doi:10.1111/cup.13860

    authors: Daou H,Hatch LA,Weinkle A,Morey GE,Messina J,Zhang X,Sokol L,Seminario-Vidal L

    更新日期:2020-09-03 00:00:00

  • Neutrophilic eccrine hidradenitis associated with induction chemotherapy.

    abstract::We report three new cases of neutrophilic eccrine hidradenitis associated with induction chemotherapy which resolves two major points. First, because two of our patients had testicular carcinoma; this firmly establishes that NEH is not exclusively seen in patients with acute myelogenous leukemia or Hodgkin's lymphoma ...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.1600-0560.1987.tb00499.x

    authors: Fitzpatrick JE,Bennion SD,Reed OM,Wilson T,Reddy VV,Golitz L

    更新日期:1987-10-01 00:00:00

  • Subungual leiomyoma in the left thumb of a 16-year-old female.

    abstract::Cutaneous leiomyomata, which are benign smooth muscle neoplasms, commonly present as dermal-based nodules or papules with smooth borders and firm consistency. Digital, particularly subungual leiomyomata are quite rare. A 16-year-old female presented to nail clinic complaining of discoloration of the lunula of the left...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/cup.12645

    authors: Komforti M,Selim MA,Bellet JS

    更新日期:2016-04-01 00:00:00

  • Acantholytic dyskeratosis of the vulva presenting with clinical features of vulval lichen sclerosus-A possible rare collision entity.

    abstract::We present a challenging case of chronic, erosive, scarring dermatosis of the vulva with clinical features of long standing lichen sclerosus (LS), namely pallor and loss of vulval architecture, but with histopathology consistently showing features of an acantholytic process. The history and clinical features of this c...

    journal_title:Journal of cutaneous pathology

    pub_type:

    doi:10.1111/cup.13560

    authors: Haddadeen C,Theaker J,Rowen D,Lotery H

    更新日期:2020-01-01 00:00:00

  • Merkel cell carcinoma co-existent with sebaceous carcinoma of the eyelid.

    abstract::Merkel cell carcinoma is occasionally associated with other types of cutaneous malignancies including squamous cell carcinoma, basal cell carcinoma and lentigo maligna. We report a case of Merkel cell carcinoma co-existent with sebaceous carcinoma in the right upper eyelid of a 61-year-old Japanese man. Histopathologi...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.1600-0560.2008.01160.x

    authors: Tanahashi J,Kashima K,Daa T,Yada N,Fujiwara S,Yokoyama S

    更新日期:2009-09-01 00:00:00

  • Activation of Src-family tyrosine kinases in hyperproliferative epidermal disorders.

    abstract:BACKGROUND:Src-family tyrosine kinases (SFKs) are important regulators of keratinocyte growth and differentiation. In a broad range of cell types, persistent activation of SFKs correlates with increased cell proliferation. In this study, we determined if SFK activity is increased in cutaneous neoplasia and psoriasis, c...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.1600-0560.2007.00807.x

    authors: Ayli EE,Li W,Brown TT,Witkiewicz A,Elenitsas R,Seykora JT

    更新日期:2008-03-01 00:00:00

  • Atypical cells on reflectance confocal microscopy may not represent melanoma: A case of axillary pigmented extramammary Paget disease.

    abstract::Pigmented extramammary Paget disease (PEMPD) is a rare intraepithelial carcinoma which can clinically resemble other pigmented neoplasms. Similarities to melanoma on dermoscopy, histopathology, and reflectance confocal microscopy (RCM) increase the risk of misdiagnosis and, consequently, mismanagement. Here, we descri...

    journal_title:Journal of cutaneous pathology

    pub_type:

    doi:10.1111/cup.13804

    authors: Chuchvara N,Reilly C,Haroon A,Wassef C,Maghari A,Rao B

    更新日期:2020-12-01 00:00:00

  • Coccygeal polypoid eccrine nevus associated with imperforate anus and unilateral multicystic kidney dysplasia.

    abstract::Eccrine nevi are rare hamartomas characterized by an increase in the number or size of eccrine glands. A polypoid form located in the coccygeal area has been described in a few cases and termed coccygeal polypoid eccrine nevus (CPEN). No association with internal malformations was reported in any of these cases. We de...

    journal_title:Journal of cutaneous pathology

    pub_type:

    doi:10.1111/cup.12718

    authors: Frouin E,Riviere B,Maillet O,Willems M,Kalfa N,Costes V,Bessis D

    更新日期:2016-08-01 00:00:00

  • Macrophage-rich epithelioid angiosarcoma mimicking malignant melanoma.

    abstract:BACKGROUND:Cutaneous epithelioid angiosarcoma is a type of cutaneous angiosarcoma and usually arise both on the head or neck of the elderly. CASE REPORT:An 86-year-old male with an epithelioid angiosarcoma of the scalp that mimicked malignant melanoma. RESULTS:A large irregular dark grey-blue plaque with an adjacent ...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.0303-6987.2006.00387.x

    authors: Brightman LA,Demierre MF,Byers HR

    更新日期:2006-01-01 00:00:00

  • Ultrastructure of deep wrinkles in the elderly.

    abstract::Deep wrinkles of 6 elderly people were investigated using electron microscopy. There were ultrastructural differences in the elastotic changes between the area of the wrinkle and the surrounding areas. Elastic fibers containing electron-dense inclusions were mostly seen in the upper dermis of the wrinkled area and wer...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.1600-0560.1987.tb00491.x

    authors: Tsuji T

    更新日期:1987-06-01 00:00:00

  • Infection by Borrelia burgdorferi and cutaneous B-cell lymphoma.

    abstract::In past years, association of primary cutaneous B-cell lymphoma (CBCL) with infection by Borrelia burgdorferi has been reported in a few patients. The evidence for a pathogenetic role was based on clinical grounds or raised titre of antibodies in serum. Both methods, however, do not prove the association between the m...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.1600-0560.1997.tb01318.x

    authors: Cerroni L,Zöchling N,Pütz B,Kerl H

    更新日期:1997-09-01 00:00:00

  • C4d immunohistochemical stain of formalin-fixed paraffin-embedded tissue as a sensitive method in the diagnosis of bullous pemphigoid.

    abstract:BACKGROUND:Bullous pemphigoid (BP) is the most common type of subepidermal bullous disease. Direct immunofluorescence (DIF) is the gold standard for diagnosis, but it requires a fresh tissue specimen. This study was conducted to evaluate the accuracy of using immunohistochemical (IHC) analysis for the detection of C4d ...

    journal_title:Journal of cutaneous pathology

    pub_type: 临床试验,杂志文章

    doi:10.1111/cup.13490

    authors: Kamyab K,Abdolreza M,Ghanadan A,Mortazavi H,Nikoo A,Motavalli F,Nasimi M

    更新日期:2019-10-01 00:00:00

  • Juvenile elastoma (Weidman). An ultrastructural study.

    abstract::Two cases of juvenile elastoma (nevus elasticus in disseminated tumors) were histologically and ultrastructurally investigated. The predominant components of this disseminated dysembryoplasia are abnormal elastic fibers. Both cases showed numerous large elastic fibers with an abundant background matrix. The elastic mi...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.1600-0560.1981.tb01001.x

    authors: Ledoux-Corbusier M,Achten G,De Dobbeleer G

    更新日期:1981-06-01 00:00:00

  • Sarcoidosis with cutaneous perineural granulomas and neurological manifestations: A potential mimicker of leprosy.

    abstract::Sarcoidosis is a granulomatous condition with diverse clinical presentations, including neurological findings. It was previously hypothesized that perineural sarcoidal granulomas in the skin may be an explanation of small-fiber neuropathy. Herein, we present a case of a 55 year old female with anesthetic cutaneous les...

    journal_title:Journal of cutaneous pathology

    pub_type:

    doi:10.1111/cup.13660

    authors: Kazi R,Kazlouskaya V,Ho J,Karunamurthy A

    更新日期:2020-07-01 00:00:00

  • Unusual subcutaneous dedifferentiated liposarcoma exhibiting coexistence of meningothelial-like whorls and inflammatory myofibroblastic tumor-like structures.

    abstract::To explore the clinicopathological features of a rare dedifferentiated liposarcoma (DDLPS) with meningothelial-like whorls, we retrospectively analyzed 46 reported cases and 1 case that we encountered. Fluorescence in situ hybridization (FISH) analysis of the MDM2 amplification status of our case was also performed. O...

    journal_title:Journal of cutaneous pathology

    pub_type:

    doi:10.1111/cup.13621

    authors: Chen S,He S,Huang H,Li L,Wang W,Cui Z,Zhang R

    更新日期:2020-02-01 00:00:00

  • Transepithelial elimination in sarcoidosis: a frequent finding.

    abstract:BACKGROUND:Transepithelial elimination is a process by which dermal materials are expelled through an active epithelial-dermal connective tissue interaction. It has been described as a regular or sporadic occurrence in a variety of dermatologic conditions, including sarcoidosis. OBSERVATION:Our patient demonstrated a ...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/cup.12253

    authors: Ismail A,Beckum K,McKay K

    更新日期:2014-01-01 00:00:00

  • Acrokeratoelastoidosis of Costa: a primary disease of the elastic tissue?

    abstract::A 24-year-old black woman from Uganda was seen for treatment of multiple papules on her hands and feet. The lesions corresponded microscopically to foci of hyperkeratosis and acanthosis. Acid orcein stain revealed marked elastic fiber fragmentation. Acrokeratoelastoidosis of Costa (AKE) was diagnosed. The same damage ...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.1600-0560.1998.tb01745.x

    authors: Fiallo P,Pesce C,Brusasco A,Nunzi E

    更新日期:1998-11-01 00:00:00

  • Subcutaneous dirofilariasis caused by Dirofilaria repens in Greece: a case report.

    abstract::Dirofilaria repens (formerly Dirofilaria conjunctiva) is a natural parasite of the subcutaneous tissues of dogs, cats and wild carnivores in Europe, Africa and Asia. Microfilariae are transmitted to humans by various species of mosquito. An autochthonous case of subcutaneous dirofilariasis is reported in a Greek patie...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.1600-0560.2008.01144.x

    authors: Tzanetou K,Gasteratos S,Pantazopoulou A,Gogou C,Konidaris D,Fragia K

    更新日期:2009-08-01 00:00:00

  • Tubular apocrine adenoma.

    abstract::Two cases of tubular apocrine adenoma were studied by light, histochemical, and electron microscopic methods. This benign apocrine hamartoma must be considered in the classification of appendage tumors, particularly those associated with organoid epithelial nevus, and may be confused with metastatic adenocarcinoma. Th...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.1600-0560.1976.tb00850.x

    authors: Umbert P,Winkelmann RK

    更新日期:1976-01-01 00:00:00

  • Specific cutaneous infiltrates of B-cell chronic lymphocytic leukemia (B-CLL) at sites typical for Borrelia burgdorferi infection.

    abstract:BACKGROUND:Cutaneous manifestations of B-cell chronic lymphocytic leukemia (B-CLL) comprise a wide spectrum of clinicopathologic presentations. In some cases, onset of skin lesions is triggered by antigenic stimulation, and specific skin infiltrates at sites of previous herpes simplex or herpes zoster infection have be...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1034/j.1600-0560.2002.290303.x

    authors: Cerroni L,Höfler G,Bäck B,Wolf P,Maier G,Kerl H

    更新日期:2002-03-01 00:00:00

  • IgG4-positive plasma cells in cutaneous Rosai-Dorfman disease: an additional immunohistochemical feature and possible relationship to IgG4-related sclerosing disease.

    abstract:BACKGROUND:Cutaneous Rosai-Dorfman disease (CRDD) shares the histopathological features of abundant plasma cells and stromal fibrosis with IgG4-related sclerosing disease. The possible role of IgG4+ plasma cells in CRDD was investigated. METHODS:Twelve cases of CRDD were reviewed, and their lesions were immunostained ...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.1600-0560.2008.01222.x

    authors: Kuo TT,Chen TC,Lee LY,Lu PH

    更新日期:2009-10-01 00:00:00

  • Lichen aureus with clonal T cells in a child possibly induced by regular consumption of an energy drink.

    abstract::Lichen aureus is a rare disease of unknown origin that is classified under the group of pigmented purpuric dermatoses. Its most important differential diagnosis is both clinically and histologically mycosis fungoides, into which the disease can proceed in very rare cases. We describe an unusual multilocular lichen aur...

    journal_title:Journal of cutaneous pathology

    pub_type: 杂志文章

    doi:10.1111/j.1600-0560.2007.00918.x

    authors: Yazdi AS,Mayser P,Sander CA

    更新日期:2008-10-01 00:00:00