Human papillomavirus-negative ileostomal chronic papillomatous dermatitis.

Abstract:

BACKGROUND:Papillomatous stoma-related skin lesions may result from irritant reactions or infection with epidermodysplasia verruciformis human papillomavirus (HPV) types. METHODS:We report upon a papillomatous lesion at the ileostoma of a 63-year-old male with familial adenomatous polyposis and colorectal adenocarcinoma. We thoroughly tested the lesion for HPV using immunohistochemistry, transmission electron microscopy, and polymerase chain reaction analyses. RESULTS:The lesion was a fleshy, multilobulated, and verrucous plaque, with hyperkeratosis, hypergranulosis, acanthosis and marked papillomatosis. The clinical and light microscopic features were suggestive of a condyloma. However, no HPV was detected. CONCLUSIONS:We suggest that the lesion most likely represents chronic papillomatous dermatitis, a reaction to mechanical and/or chemical irritation usually associated with urostomies and only rarely observed with ileostomies. This case highlights the clinical, diagnostic and therapeutic aspects of an unusual cutaneous morbidity associated with ileostomies.

journal_name

J Cutan Pathol

authors

Williams CM,Wieland U,Rodning CB,Horenstein MG

doi

10.1046/j.0303-6987.2003.048.x

keywords:

subject

Has Abstract

pub_date

2003-04-01 00:00:00

pages

271-4

issue

4

eissn

0303-6987

issn

1600-0560

pii

048

journal_volume

30

pub_type

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