Matrical carcinoma of the skin.

abstract：:A case of eosinophilic ulcer of the tongue is presented. Although the entity is rarely described, the distinctive histopathologic pattern featuring the remarkable presence of eosinophils in the superficial corium and in between muscle bundles, together with the benign clinical course, make a diagnosis possible. ...

journal_title：Journal of cutaneous pathology

authors： Borroni G,Pericoli R,Gabba P,Rosso R,Rabbiosi G

更新日期：1984-08-01 00:00:00

abstract：BACKGROUND:Psoriasis vulgaris is a common chronic inflammatory dermatosis. Disorders in keratinocyte proliferation, differentiation, inflammation and immune dysregulation are the major factors implicated in the pathogenesis of psoriasis vulgaris. METHODS:The study was performed in skin specimens of 25 patients with ps...

journal_title：Journal of cutaneous pathology

authors： Doger FK,Dikicioglu E,Ergin F,Unal E,Sendur N,Uslu M

更新日期：2007-03-01 00:00:00

abstract：:A 31 year old Indian woman presented with bilateral axillary masses that became noticeable with the onset of puberty. The masses exhibited similar consistency to the adjacent normal breast tissue but lacked an associated nipple complex. The clinical impression was lipoma; however, mammography, ultrasonography and skin...

journal_title：Journal of cutaneous pathology

authors： Ghosn SH,Khatri KA,Bhawan J

更新日期：2007-12-01 00:00:00

abstract：INTRODUCTION:The term spitzoid melanoma (SM) is reserved for a rare group of tumors with striking resemblance to Spitz nevus, often developing in children diagnosed in retrospect after the development of metastases. OBJECTIVES:To determine the biological significance of SM and to analyze the effectiveness of adjuvant ...

journal_title：Journal of cutaneous pathology

authors： Paradela S,Fonseca E,Pita S,Kantrow SM,Goncharuk VN,Diwan H,Prieto VG

更新日期：2009-07-01 00:00:00

abstract：:A case of an osteogenic desmoplastic melanoma occurring on the sole of the foot of a 60-year-old African American man is described. The tumor measured 4.8 cm in greatest dimension, invaded to a thickness of 2.2 cm and metastasized to four of ten inguinal lymph nodes. The majority of the tumor had a classic desmoplasti...

journal_title：Journal of cutaneous pathology

authors： Emanuel PO,Idrees MT,Leytin A,Kwon EJ,Phelps RG

更新日期：2007-05-01 00:00:00

abstract：:Desmoplastic trichoepithelioma (DTE) is a benign follicular tumor occurring most commonly within facial skin of young and middle-aged women, morphologically characterized by a superficial dermal proliferation of basaloid cells growing in narrow strands embedded in a desmoplastic stroma associated with small keratinizi...

journal_title：Journal of cutaneous pathology

authors： Jedrych J,Leffell D,McNiff JM

更新日期：2012-03-01 00:00:00

abstract：:Malignant mesothelioma (MM) is an aggressive and invasive neoplasm primarily affecting the pleura, peritoneum and pericardium. While mesothelioma commonly metastasizes to visceral organs, it has rarely been documented to involve the skin and subcutaneous tissue. There is a paucity of reports of cutaneous metastatic me...

journal_title：Journal of cutaneous pathology

authors： Ward RE,Ali SA,Kuhar M

更新日期：2017-12-01 00:00:00

abstract：:During the past decade, a group of cells located in the dermis and possessing a dendritic morphology have emerged from obscurity and become recognized as important members of the "dermal immune system". This group of cells is characterized by a considerable degree of immunophenotypic and functional heterogeneity. In t...

journal_title：Journal of cutaneous pathology

authors： Nestle FO,Nickoloff BJ

更新日期：1995-10-01 00:00:00

abstract：:A 46-year-old man had a cystic mass on the right side of his scalp. Histological examination revealed a cystic dermal nodule composed of relatively circumscribed lobules of proliferating squamous epithelium, with atypical mitoses and dyskeratotic cells of invasive structure, which was diagnosed as proliferating tricho...

journal_title：Journal of cutaneous pathology

authors： Masui Y,Komine M,Kadono T,Ishiura N,Maekawa T,Ihn H,Kikuchi K,Tamaki K

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:The aim of this study was to evaluate the effectiveness of CD117 immunostaining for diagnosing cutaneous adnexal tumors, which has not been previously established. METHODS:CD117 immunostaining was performed on representative sections of 87 clinicopathologically confirmed cutaneous apocrine/eccrine tumors, 1...

journal_title：Journal of cutaneous pathology

authors： Goto K

更新日期：2015-07-01 00:00:00

abstract：:Keratoacanthoma (KA), an epithelial neoplasm occurring in sun-exposed skin of the elderly, is considered a well-differentiated form of conventional squamous cell carcinoma (SCC) that often follows a course of spontaneous regression. Distinguishing KA from conventional SCC or pseudocarcinomatous epithelial hyperplasia ...

journal_title：Journal of cutaneous pathology

authors： Shah K,Kazlouskaya V,Lal K,Molina D,Elston DM

更新日期：2014-02-01 00:00:00

abstract：:Pigmented extramammary Paget disease (PEMPD) is a rare intraepithelial carcinoma which can clinically resemble other pigmented neoplasms. Similarities to melanoma on dermoscopy, histopathology, and reflectance confocal microscopy (RCM) increase the risk of misdiagnosis and, consequently, mismanagement. Here, we descri...

journal_title：Journal of cutaneous pathology

authors： Chuchvara N,Reilly C,Haroon A,Wassef C,Maghari A,Rao B

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Changes in the clinical appearance of benign dermal nevi during pregnancy may be concerning for malignant transformation. Because the hormonal milieu of pregnancy has not proven to alter their banal behavior, histologic characterization is needed to prevent over-diagnosis and unnecessary treatment. METHODS:...

journal_title：Journal of cutaneous pathology

authors： Chan MP,Chan MM,Tahan SR

更新日期：2010-08-01 00:00:00

abstract：:Trichilemmoma is considered a benign neoplasm derived from the outer root sheath of the hair follicle. Although the histogenesis of the lesion is unknown, a relationship between human papillomavirus (HPV) infection and development of these tumors has been suggested on morphologic observations. In order to determine wh...

journal_title：Journal of cutaneous pathology

authors： Leonardi CL,Zhu WY,Kinsey WH,Penneys NS

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:Tumors with similar or identical histopathologic features have been termed basaloid follicular hamartoma (BFH) or infundibulocystic basal cell carcinoma (BCC). BCC typically lacks immunoreactivity with cytokeratin 20 (CK20) and pleckstrin homology-like domain, family A, member 1 protein (PHLDA1). AIM:A seri...

journal_title：Journal of cutaneous pathology

authors： Honarpisheh H,Glusac EJ,Ko CJ

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Cutaneous leishmaniasis displays considerable variation in its histopathological and clinical presentation. Clinically, it progresses from a papule into a painless ulcerated and crusted nodule/papule. Microscopically, it progresses from sheets of amastigote-filled histiocytes to granulomatous inflammation. ...

journal_title：Journal of cutaneous pathology

authors： Saab J,Fedda F,Khattab R,Yahya L,Loya A,Satti M,Kibbi AG,Houreih MA,Raslan W,El-Sabban M,Khalifeh I

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Cardiac angiosarcoma is a rare tumor that has a predilection for middle-aged males and a marked predominance in the right atrium. The tumor may present abruptly with a fulminant clinical course. Initial presentation with metastatic disease is rare. Only one case has been reported of a patient who presented w...

journal_title：Journal of cutaneous pathology

authors： Val-Bernal JF,Figols J,Arce FP,Sanz-Ortiz J

更新日期：2001-05-01 00:00:00

abstract：:We report a case of disseminated Trichosporon asahii in a patient on systemic antifungal therapy who presented with multiple cutaneous nodules suggestive of fungal infection. Histologic features resembled neutrophilic eccrine hidradenitis but staining with periodic acid-Schiff and Gomori methenamine silver confirmed t...

journal_title：Journal of cutaneous pathology

authors： Galligan ER,Fix L,Husain S,Zachariah P,Yamashiro DJ,Lauren CT

更新日期：2019-02-01 00:00:00

abstract：:The histogenesis of atypical fibroxanthoma (AFX) and its relationship to malignant fibrous histiocytoma (MFH) are a subject of controversy. Many investigators have proposed that AFX may represent a reactive process, while others contend that it is a true fibrohistiocytic neoplasm, closely related to MFH. In an attempt...

journal_title：Journal of cutaneous pathology

authors： Worrell JT,Ansari MQ,Ansari SJ,Cockerell CJ

更新日期：1993-06-01 00:00:00

abstract：:Two cases of juvenile elastoma (nevus elasticus in disseminated tumors) were histologically and ultrastructurally investigated. The predominant components of this disseminated dysembryoplasia are abnormal elastic fibers. Both cases showed numerous large elastic fibers with an abundant background matrix. The elastic mi...

journal_title：Journal of cutaneous pathology

authors： Ledoux-Corbusier M,Achten G,De Dobbeleer G

更新日期：1981-06-01 00:00:00

abstract：:Bullous pemphigoid (BP) antigen and alpha 6 integrin are hemidesmosome-associated glycoproteins of basal keratinocytes. In this work, the immunoreactivity of antibodies to BP and to alpha 6 in salt- or dispase-split human skin, and in 46 biopsy specimens of various genetic and autoimmune bullous dermatoses taken from ...

journal_title：Journal of cutaneous pathology

authors： Kanitakis J,Zambruno G,Vassileva S,Giannetti A,Thivolet J

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:Merkel cell carcinoma (MCC) is an aggressive neoplasm, which is often associated with Merkel cell polyomavirus (MCPyV). Programmed death-1 (PD-1) and its ligand PD-L1 are key players of the tumor microenvironment (TME). METHODS:Fourteen paraffin-embedded tissue samples of MCC were stratified by their MCPyV ...

journal_title：Journal of cutaneous pathology

authors： Mitteldorf C,Berisha A,Tronnier M,Pfaltz MC,Kempf W

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Fatty acid synthase (FAS), the key enzyme responsible for the synthesis of fatty acids, is weakly expressed in some normal human tissues. Recently, FAS has been demonstrated to be overexpressed in many non-neoplastic highly proliferative lesions and in aggressive carcinomas with poor outcome, including colon...

journal_title：Journal of cutaneous pathology

authors： Innocenzi D,Alò PL,Balzani A,Sebastiani V,Silipo V,La Torre G,Ricciardi G,Bosman C,Calvieri S

更新日期：2003-01-01 00:00:00

abstract：:A 59-year-old female with a cystic fibroepithelioma of Pinkus is presented. The clinical and histopathological features of this unusual variant of basal cell carcinoma are discussed. ...

journal_title：Journal of cutaneous pathology

authors： Jones CC,Ansari SJ,Tschen JA

更新日期：1991-06-01 00:00:00

abstract：:Sarcoidosis is a granulomatous condition with diverse clinical presentations, including neurological findings. It was previously hypothesized that perineural sarcoidal granulomas in the skin may be an explanation of small-fiber neuropathy. Herein, we present a case of a 55 year old female with anesthetic cutaneous les...

journal_title：Journal of cutaneous pathology

authors： Kazi R,Kazlouskaya V,Ho J,Karunamurthy A

更新日期：2020-07-01 00:00:00

abstract：:Basic fibroblast growth factor (bFGF) is a growth factor and an angiogenesis factor which may play a role in the evolution of cutaneous malignant melanoma (CMM). In this study, we evaluated the distribution of bFGF in CMM using immunochemical methods and correlated the pattern of bFGF expression with the clinical cour...

journal_title：Journal of cutaneous pathology

authors： al-Alousi S,Barnhill R,Blessing K,Barksdale S

更新日期：1996-12-01 00:00:00

abstract：:A tumor of 60 years' duration overlying the sternum of an 87-year-old woman is described. Histologically, the tumor was composed of lobules and cords of epithelial cells with finely granular, eosinophilic cytoplasm. The epithelial nests were floating in large pools of mucinous stroma, separated by thin fibrovascular s...

journal_title：Journal of cutaneous pathology

authors： Sakamoto F,Ito M,Matumura G,Sato Y,Kimura S

更新日期：1991-04-01 00:00:00

abstract：:Acral pseudolymphomatous angiokeratoma of children (APACHE) is a disease comprised by a dense dermal infiltrate of B-lymphocytes and T-lymphocytes in which prominent blood vessels with plump endothelium are found. In the past, the lesion was interpreted as a variant of angiokeratoma, a vascular malformation, or a nevu...

journal_title：Journal of cutaneous pathology

authors： Fernandez-Flores A,Fierro S,Larralde M

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:p53 mutations are etiologically associated with the development of squamous cell carcinomas (SCCs) or with exposure to specific carcinogens. The study was conducted to examine the relationship of immunohistochemistry (IHC) scores between altered p53 protein expression in relation to patient's habits and hist...

journal_title：Journal of cutaneous pathology

authors： Bukhari MH,Niazi S,Chaudhry NA

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Chronic amastigote-negative cutaneous leishmaniasis (CL) is a diagnostic challenge, as the parasite load may be low, or absent in biopsy tissue sections. METHODS:A series of consecutive biopsy specimens, taken from 130 patients with a diagnosis of granulomatous dermatitis of unknown etiology, were reviewed....

journal_title：Journal of cutaneous pathology

authors： Tomasini C,Moneghini L,Barbui AM

更新日期：2017-06-01 00:00:00