C4d immunohistochemical stain of formalin-fixed paraffin-embedded tissue as a sensitive method in the diagnosis of bullous pemphigoid.

abstract：BACKGROUND:Chromoblastomycosis is a chronic, suppurative, granulomatous mycosis usually confined to skin and subcutaneous tissues. The host defense mechanisms in chromoblastomycosis have not been extensively investigated. The purpose of the present study was to determine the distribution and pathways of the fungal anti...

journal_title：Journal of cutaneous pathology

authors： Sotto MN,De Brito T,Silva AM,Vidal M,Castro LG

更新日期：2004-01-01 00:00:00

abstract：:Lymphomatoid granulomatosis (LG) is a rare Epstein-Barr virus (EBV)-associated B-cell lymphoproliferative disorder presenting in middle adulthood that nearly always affects the lungs and shows cutaneous involvement in up to 50% of cases. Skin lesions are present at the time of diagnosis in roughly one-third of patient...

journal_title：Journal of cutaneous pathology

authors： Rysgaard CD,Stone MS

更新日期：2015-03-01 00:00:00

abstract：:Recent advances in the understanding of the metastatic phenomenon in cancer have led to the description of a metastatic niche. This concept describes a site prepared for the tumor cells in areas frequently associated with metastasis for the individual tumor studied. This niche is a "soil" that allows for the tumor cel...

journal_title：Journal of cutaneous pathology

authors： Mihm MC Jr,Nelson JS

更新日期：2010-04-01 00:00:00

abstract：:Exposure to silver-containing compounds can result in reversible discoloration of the skin, presenting as an irregular brown or black macule, which can have a clinical appearance similar to melanoma. Both the clinical scenario and the histopathology are unique. Silver nitrate darkens with exposure to light, and the ar...

journal_title：Journal of cutaneous pathology

authors： Ondrasik RM,Jordan P,Sriharan A

更新日期：2020-12-01 00:00:00

abstract：:A 57-year-old woman with cutaneous mastocytosis of 23 years duration developed a hyperpigmented abdominal plaque composed of confluent indurated papules that enlarged for a period of 1 year to 12 x 8 cm. Biopsy showed dermal infiltration by closely packed spindle-shaped mast cells, fibroblasts, collagen, and scattered...

journal_title：Journal of cutaneous pathology

authors： Wood C,Sina B,Webster CG,Kurgansky D,Drachenberg CB,Reedy EA

更新日期：1992-04-01 00:00:00

abstract：:Two cases of juvenile elastoma (nevus elasticus in disseminated tumors) were histologically and ultrastructurally investigated. The predominant components of this disseminated dysembryoplasia are abnormal elastic fibers. Both cases showed numerous large elastic fibers with an abundant background matrix. The elastic mi...

journal_title：Journal of cutaneous pathology

authors： Ledoux-Corbusier M,Achten G,De Dobbeleer G

更新日期：1981-06-01 00:00:00

abstract：:Pilomatrix (pilomatrical) carcinoma is a rare cutaneous adnexal tumor with matrical differentiation and recurrent and metastatic potential. Sarcomatoid pilomatrix carcinoma is a rare variant which shows a sarcomatoid component intermingling with the epithelial one. There are only 4 cases previously published. We prese...

journal_title：Journal of cutaneous pathology

authors： Fernandez-Flores A,Cassarino DS

更新日期：2018-07-01 00:00:00

abstract：:Respiratory cysts are benign lesions lined by normal respiratory epithelium. There are few reported cases localized to the orbit, while those of the eyelid are exceedingly rare. Respiratory cysts usually arise either from a non-hereditary congenital malformation, where they are distinguished as choristomatous, or from...

journal_title：Journal of cutaneous pathology

authors： Yeh C,Atillasoy C,Seykora JT,Lee V

更新日期：2021-01-01 00:00:00

abstract：:Two young patients with conjunctival compound nevi are presented to illustrate two types of abnormalities that lead to difficulty in distinction of these nevi from invasive melanomas. In Case 1, inflammation is associated with disruption of the nevus cell architecture and cytologic atypia. In Case 2, the occurrence of...

journal_title：Journal of cutaneous pathology

authors： Kabukçuoğlu S,McNutt NS

更新日期：1999-05-01 00:00:00

abstract：AIM:In the absence of mites, the histologic diagnosis of human scabies can be difficult. Scabies can mimic a variety of inflammatory and lymphoproliferative disorders. It is under-recognized that scabies can also mimic Langerhans cell histiocytosis. METHODS:Sixteen examples of scabies were reviewed histologically and ...

journal_title：Journal of cutaneous pathology

authors： Bhattacharjee P,Glusac EJ

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:BRAF, a serine/threonine kinase, is a component of the retrovirus-associated sequence (RAS)-RAF-extracellular-regulated protein kinase (ERK)-MAP kinase signal transduction pathway mediating signals from RAS to ERK. The T1796A single point mutation in exon 15 of the BRAF gene has recently been reported in a h...

journal_title：Journal of cutaneous pathology

authors： Palmedo G,Hantschke M,Rütten A,Mentzel T,Hügel H,Flaig MJ,Yazdi AS,Sander CA,Kutzner H

更新日期：2004-03-01 00:00:00

abstract：:Facial inflammatory dermatoses can be difficult to diagnose in their early stages; skin biopsy may help but often shows indeterminate features. The aims of our study were to identify patients presenting with a facial dermatosis requiring skin biopsy, in whom the initial histological features were classified as "non-sp...

journal_title：Journal of cutaneous pathology

authors： Rhodes LE,Parslew RA,Ashworth J

更新日期：1995-04-01 00:00:00

abstract：:A case of an unusual benign apocrine hamartoma was studied by light microscopic, immunohistochemical, and electron microscopic methods. This tumor clinically showed a linear configuration and was located on the midline chest of a pubescent male. Microscopic studies revealed features of both a tubular apocrine adenoma ...

journal_title：Journal of cutaneous pathology

authors： Epstein BA,Argenyi ZB,Goldstein G,Whitaker D

更新日期：1990-02-01 00:00:00

abstract：:Patients with primary immunodeficiency are at increased risk for malignancy, especially hematologic neoplasms. This paper reports a unique case of a 47-year-old man with X-linked agammaglobulinemia who presented with progressive asymptomatic violaceous papules and plaques on his face, hands, and trunk for 1 year. Skin...

journal_title：Journal of cutaneous pathology

authors： Daou H,Hatch LA,Weinkle A,Morey GE,Messina J,Zhang X,Sokol L,Seminario-Vidal L

更新日期：2020-09-03 00:00:00

abstract：BACKGROUND:p53 mutations are etiologically associated with the development of squamous cell carcinomas (SCCs) or with exposure to specific carcinogens. The study was conducted to examine the relationship of immunohistochemistry (IHC) scores between altered p53 protein expression in relation to patient's habits and hist...

journal_title：Journal of cutaneous pathology

authors： Bukhari MH,Niazi S,Chaudhry NA

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Cutaneous lymphatic malformations represent a group of heterogeneous diseases caused by developmental defects of lymphatic system. OBJECTIVE:The purpose of this study was to report the clinical, histopathological and immunohistochemical features of a distinctive lymphatic malformation. METHODS:Twelve patie...

journal_title：Journal of cutaneous pathology

authors： Wang L,Gao T,Wang G

更新日期：2013-07-01 00:00:00

abstract：:Benign lymphangioendothelioma is a rare locally infiltrative vascular neoplasm, presenting as a slow-growing, asymptomatic, reddish-violaceous plaque. Histopathologically, it is characterized by irregular and thin-walled vascular spaces, lined by a single and discontinuous layer of flat endothelial cells, dissecting d...

journal_title：Journal of cutaneous pathology

authors： Revelles JM,Díaz JL,Angulo J,Santonja C,Kutzner H,Requena L

更新日期：2012-10-01 00:00:00

abstract：:Endometriosis is a condition where endometrial glands and stroma are ectopically located in sites other than the uterine cavity. Cutaneous endometriosis is very rare, representing approximately 1.1% of cases of extrapelvic endometriosis. We report a case of a 44-year-old female with no prior surgical history who prese...

journal_title：Journal of cutaneous pathology

authors： Farooq U,Laureano AC,Miteva M,Elgart GW

更新日期：2011-06-01 00:00:00

abstract：:Malignant transformation occurred in pre-existing sweat gland tumors in 7 patients. Three lesions showed an histologic pattern of eccrine spiradenoma, 2 eccrine poroma, one cylindroma and one papillary eccrine adenoma. Malignant transformation was histologically characterized by the presence of solid tumor areas popul...

journal_title：Journal of cutaneous pathology

authors： Galadari E,Mehregan AH,Lee KC

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:Hereditary hypotrichosis simplex (MIM 146520, HHS) is a rare form of nonsyndromic alopecia. The locus for autosomal dominant HHS was mapped to 18p11.32-p11.23 and 6p21.3, respectively, suggestive of genetic heterogeneity. AIM:To identify the disease-causing gene for a four-generation Chinese family with dom...

journal_title：Journal of cutaneous pathology

authors： Xu C,Zhang L,Chen N,Su B,Pan CM,Li JY,Zhang GW,Liu Z,Sheng Y,Song HD

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND:Distinguishing an irritated seborrheic keratosis (ISK) from a squamous cell carcinoma in situ (SCCIS) can occasionally be challenging, both histologically and clinically. The purpose of this study was to determine if an immunohistochemical profile of select markers can aid in differentiating these two entiti...

journal_title：Journal of cutaneous pathology

authors： Richey JD,Deng AC,Dresser K,O'Donnell P,Cornejo KM

更新日期：2018-08-01 00:00:00

abstract：:Sarcoidosis is a granulomatous condition with diverse clinical presentations, including neurological findings. It was previously hypothesized that perineural sarcoidal granulomas in the skin may be an explanation of small-fiber neuropathy. Herein, we present a case of a 55 year old female with anesthetic cutaneous les...

journal_title：Journal of cutaneous pathology

authors： Kazi R,Kazlouskaya V,Ho J,Karunamurthy A

更新日期：2020-07-01 00:00:00

abstract：:Cutaneous lymphadenoma is an uncommon benign neoplasm often considered to be an adamantinoid variant of trichoblastoma. Lesions present in both sexes, between 14 and 87 years of age, and are mainly located on the head and neck. Cases in children are rare and there is only 1 previous case of a congenital lymphadenoma. ...

journal_title：Journal of cutaneous pathology

authors： Fernandez-Flores A,Nicklaus-Wollenteit I,Sathishkumar D,Diba V,Richard B,Carr R,Moss C,Nagy A,Ogboli M,Colmenero I

更新日期：2017-11-01 00:00:00

abstract：:Benign fibrous histiocytoma of the skin or dermatofibroma (DF) has been regarded as a fibrohistiocytic tumor. Whether DF is a neoplastic growth or a reactive process has not been settled. Since a neoplastic process is clonal in nature, clonal analysis of DF was conducted to see if DF is a clonal disease. Fresh specime...

journal_title：Journal of cutaneous pathology

authors： Chen TC,Kuo T,Chan HL

更新日期：2000-01-01 00:00:00

abstract：:The term "outer root sheath acanthoma" is proposed to specify a distinctive keratosis exhibiting outer root sheath differentiation. This lesion features anastamosing columns of keratinocytes emanating from the undersurface of the epidermis that respectively demonstrate, with progressive descent into the upper dermis, ...

journal_title：Journal of cutaneous pathology

authors： Reichel M,Heilman ER

更新日期：1999-10-01 00:00:00

abstract：:A histologically unique condition of the sweat duct was found in a miliaria-like papular eruption on the extensor surfaces of extremities of a 41-year-old female patient. The hypertrophic epithelium of the sweat duct wall consisted of extensively vacuolated clear cells. There was mild hyperkeratosis around the sweat d...

journal_title：Journal of cutaneous pathology

authors： Izaki S,Kono E,Hirai A,Kitamura K

更新日期：1994-06-01 00:00:00

abstract：:Post-transplant lymphoproliferative disorder (PTLD) is a lymphoid proliferation that develops as a complication of solid organ or bone marrow transplants. PTLD limited to the skin is very rare. Plasmacytoma-like PTLD is an uncommon variant of monomorphic PTLD. Its presentation in the skin is extraordinary with very fe...

journal_title：Journal of cutaneous pathology

authors： Molina-Ruiz AM,Pulpillo A,Lasanta B,Zulueta T,Andrades R,Requena L

更新日期：2012-07-01 00:00:00

abstract：:We report a new case of a Japanese man who developed a tubular apocrine adenoma in association with syringocystadenoma papilliferum. The differences in the histopathological and immunohistochemical findings in these 2 tumors are described. This is the first immunohistochemical study of tubular apocrine adenoma. ...

journal_title：Journal of cutaneous pathology

authors： Ansai S,Watanabe S,Aso K

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND:Pemphigoides gestationis (PG) is a blistering disorder of pregnancy caused by antibodies against basement membrane proteins. They are directed against the 180 kD bullous pemphigoid antigen (BPAg2), towards the epitopes within the NC 16A domain. There are many similarities between pemphigoid gestationis and b...

journal_title：Journal of cutaneous pathology

authors： Patton T,Plunkett RW,Beutner EH,Deng JS,Jukic DM

更新日期：2006-04-01 00:00:00

abstract：:Polarizable calcium oxalate (CaOx) crystals have been well documented in breast biopsies, generally associated with benign apocrine metaplasia. In contrast, polarizable crystals are only rarely reported in skin adnexal neoplasms. We report 3 different cases of sweat gland tumors with polarizable crystals morphological...

journal_title：Journal of cutaneous pathology

authors： Johnson G,Gardner JM,Shalin SC

更新日期：2017-08-01 00:00:00