IgG4 as the predominant IgG subclass in pemphigoides gestationis.

abstract：BACKGROUND:Apoptosis is important for maintenance of tissue homeostasis and often dysregulated in cutaneous neoplasms. The apoptosis inhibitor survivin is expressed in melanoma and non-melanoma skin cancers and benign keratinocytic lesions. Its expression has not been studied in melanocytic nevi. OBJECTIVE:We determin...

journal_title：Journal of cutaneous pathology

authors： Florell SR,Bowen AR,Hanks AN,Murphy KJ,Grossman D

更新日期：2005-01-01 00:00:00

abstract：:The expression of cytokeratins in 10 cases of clear cell hidradenoma, including 3 cases of solid cystic hidradenoma, were examined using 21 kinds of monoclonal antibodies. We divided them into three histologic patterns: massive nests with a few lumina (M nests), nests with some tubular lumina (L nests), and nests in s...

journal_title：Journal of cutaneous pathology

authors： Ohnishi T,Watanabe S

更新日期：1997-01-01 00:00:00

abstract：:Confocal laser scanning microscopy (CLSM) is a new optical microscopic technique, which offers significant advantages over conventional microscopy. CLSM is microscopy of optical sections. Light, which is emitted from regions other than the focal plane, is cut off by introducing a diaphragm in the beam path. The result...

journal_title：Journal of cutaneous pathology

authors： Fink-Puches R,Hofmann-Wellenhof R,Smolle J,Kerl H

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND:Infection with parvovirus B19 (B19) has been associated with connective tissue disease (CTD) stigmata, namely, a systemic lupus erythematosus (SLE)-like illness, seronegative polyarthritis resembling rheumatoid arthritis, and vasculitis. The dermatopathology and pathogenetic basis of such B19-associated CTD-...

journal_title：Journal of cutaneous pathology

authors： Crowson AN,Magro CM,Dawood MR

更新日期：2000-11-01 00:00:00

abstract：:Although the histogenesis of sebaceous carcinomas remains unclear, the occurrence of intraepidermal or intraepithelial sebaceous carcinoma in the epidermis or conjunctiva may suggest de novo histogenesis. This report describes a case of sebaceous carcinoma within preexisting rippled/carcinoid pattern sebaceoma. This l...

journal_title：Journal of cutaneous pathology

authors： Misago N,Toda S

更新日期：2016-01-01 00:00:00

abstract：:The majority of findings in relation to warts have been passed on from one textbook to the other since the end of the last century. More recent studies have been carried out with the electron microscope. But information is lacking as to histology, histochemistry, examination with the phase-contrast microscope, with th...

journal_title：Journal of cutaneous pathology

authors： Steigleder GK

更新日期：1978-04-01 00:00:00

abstract：:Cellular adhesion molecules are newly identified mediators of angiogenesis. Infantile hemangiomas, characterized in the early stages by a proliferation of poorly differentiated vessels followed in the late stages by a vascular differentiation and regression of the tumor, represent an interesting model to study angioge...

journal_title：Journal of cutaneous pathology

authors： Verkarre V,Patey-Mariaud de Serre N,Vazeux R,Teillac-Hamel D,Chretien-Marquet B,Le Bihan C,Leborgne M,Fraitag S,Brousse N

更新日期：1999-01-01 00:00:00

abstract：:Two cases of tubular apocrine adenoma were studied by light, histochemical, and electron microscopic methods. This benign apocrine hamartoma must be considered in the classification of appendage tumors, particularly those associated with organoid epithelial nevus, and may be confused with metastatic adenocarcinoma. Th...

journal_title：Journal of cutaneous pathology

authors： Umbert P,Winkelmann RK

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:It is often challenging to reliably assess the number of lesional melanocytes in intraepidermal melanocytic proliferations involving sun-damaged skin. Therefore, dermatopathologists routinely use immunostains to help differentiate melanocytes from surrounding keratinocytes. METHODS:Forty-three cases of sola...

journal_title：Journal of cutaneous pathology

authors： Kim J,Taube JM,McCalmont TH,Glusac EJ

更新日期：2011-10-01 00:00:00

abstract：:Cutaneous leiomyomata, which are benign smooth muscle neoplasms, commonly present as dermal-based nodules or papules with smooth borders and firm consistency. Digital, particularly subungual leiomyomata are quite rare. A 16-year-old female presented to nail clinic complaining of discoloration of the lunula of the left...

journal_title：Journal of cutaneous pathology

authors： Komforti M,Selim MA,Bellet JS

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Fibrofolliculomas and trichodiscomas are benign dermal neoplasms that likely derive from the mantle of the hair follicle and can occur sporadically or in association with Birt-Hogg-Dube syndrome (BHDS). Little is known about the pathogenesis and immunophenotypic properties of these entities. METHODS:We inve...

journal_title：Journal of cutaneous pathology

authors： Collins GL,Somach S,Morgan MB

更新日期：2002-10-01 00:00:00

abstract：:Extraskeletal Ewing's sarcoma has been recognized as being histologically indistinguishable from Ewing's sarcoma of bone. Although the occurrence of extraosseous Ewing's sarcoma in deep soft tissues has been well described, such cutaneous lesions are rare. We report the clinical history, histopathologic findings, and ...

journal_title：Journal of cutaneous pathology

authors： Peters MS,Reiman HM,Muller SA

更新日期：1985-12-01 00:00:00

abstract：BACKGROUND:The present study evaluates the signal transducer and activator of transcription-3 (STAT-3) expression and activation in actinic cheilitis (AC) and the relationship of this protein with the degree of epithelial dysplasia. METHODS:Twenty-five cases of AC were analyzed. Normal lip mucosa was used as a control...

journal_title：Journal of cutaneous pathology

authors： Cury PR,Furuse C,de Araújo NS,de Araújo VC

更新日期：2007-08-01 00:00:00

abstract：:We present a case of a 64-year-old man with refractory acute myeloid leukemia and trisomy 8 who developed leukemia cutis. Interphase fluorescence in situ hybridization (FISH) was performed on a paraffin-embedded skin section. FISH confirmed a population of cells with trisomy 8 in the blastic infiltrates involving the ...

journal_title：Journal of cutaneous pathology

authors： Shvartsbeyn M,Meehan SM,Gu P,Nierodzik ML,Perle MA

更新日期：2012-11-01 00:00:00

abstract：:The internal organization of plasma membranes was studied in seven subjects with pemphigus vulgaris and in one subject with familial pemphigus using the freeze-fracture technique. The results obtained seem to suggest that the acantholytic process is produced in a similar fashion whatever the pathogenic agent and that ...

journal_title：Journal of cutaneous pathology

authors： Caputo R,Innocenti M,Gasparini G

更新日期：1980-04-01 00:00:00

abstract：:Epithelioid cells with foamy cytoplasm (histiocytoid features) are typical histopathologic findings among benign and malignant histiocytic neoplasms such as xanthoma and atypical fibroxanthoma. However, these changes are unusual in melanoma, which is typically composed of nested and variably pigmented atypical epithel...

journal_title：Journal of cutaneous pathology

authors： Farah M,Nagarajan P,Torres-Cabala CA,Curry JL,Amaria RN,Wargo J,Tawbi H,Ivan D,Prieto VG,Tetzlaff MT,Aung PP

更新日期：2018-07-01 00:00:00

abstract：:Characteristic moniliform hairs of monilethrix were ultrastructurally examined. By scanning electron microscope, nodes and internodes were seen alternating on the affected hair; the nodes were normal in appearance and thickness, while the internodes were thin and showed ridges and flutes. By transmission electron micr...

journal_title：Journal of cutaneous pathology

authors： Ito M,Hashimoto K,Yorder FW

更新日期：1984-12-01 00:00:00

abstract：BACKGROUND:Recently, an intriguing concept was introduced into the literature that defines the area underlying the nail bed as a specific mesenchymal substructure unique to the nail organ. It has been termed onychodermis. The onychodermis expresses CD10 with remarkable specificity. Herein, we compare adult and fetal hu...

journal_title：Journal of cutaneous pathology

authors： Sellheyer K,Nelson P

更新日期：2013-05-01 00:00:00

abstract：:Exposure to silver-containing compounds can result in reversible discoloration of the skin, presenting as an irregular brown or black macule, which can have a clinical appearance similar to melanoma. Both the clinical scenario and the histopathology are unique. Silver nitrate darkens with exposure to light, and the ar...

journal_title：Journal of cutaneous pathology

authors： Ondrasik RM,Jordan P,Sriharan A

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:A reduction in the expression of the pan T-cell markers CD7 and CD62L supports an endogenous T-cell dyscrasia. Previously, clone availability for CD62L restricted its application to frozen tissue sections. MATERIALS AND METHODS:A nonavidin/biotin technique to examine CD3, CD62L, and CD7 in paraffin formalin...

journal_title：Journal of cutaneous pathology

authors： Magro CM,Sachdeva MP,Crowson AN,Barusevicius A,Baran PN,Kovatich AJ

更新日期：2005-01-01 00:00:00

abstract：:We have quantified perivascular mast cells in cases of urticaria pigmentosa, urticaria, and dermal hypersensitivity reactions. To facilitate reproducibility, the mast cells were counted for a precisely defined vessel unit. These vessel units were divided arbitrarily into those < or = 55 microns and > 55 microns in lar...

journal_title：Journal of cutaneous pathology

authors： Sweet WL,Smoller BR

更新日期：1996-06-01 00:00:00

abstract：:We describe a case of syringocystadenoma papilliferum (SCAP) with a unique histopathology. A 50-year-old Japanese woman presented with a pedunculated tumor in the pubic region. Histopathological examination showed that the tumor was composed of basaloid cell proliferation interconnecting from the epidermis to the derm...

journal_title：Journal of cutaneous pathology

authors： Kishibe M,Iwasaki T,Takahashi I,Ishida-Yamamoto A

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:We encountered a distinctive pattern of dysplastic intraepidermal melanocytic proliferation, which defies classification as a dysplastic melanocytic nevus, but in which the morphologic features fall short of a diagnosis of melanoma in situ. We designate such lesions as de novo intraepidermal epithelioid mela...

journal_title：Journal of cutaneous pathology

authors： Sachdeva M,Frambach GE,Crowson AN,Deng AC,Mihm MC Jr,Magro CM

更新日期：2005-10-01 00:00:00

abstract：:Many patients who present with patch and early plaque stage mycosis fungoides follow an indolent course and survive for many years following diagnosis. A certain subset of patients, however, have rapidly progressive disease leading to accelerated demise. We examined 21 histologic sections from initial biopsies taken f...

journal_title：Journal of cutaneous pathology

authors： Smoller BR,Detwiler SP,Kohler S,Hoppe RT,Kim YH

更新日期：1998-07-01 00:00:00

abstract：:Pleomorphic fibromas represent dome-shaped or polypoid cutaneous lesions characterized by a paucicellular and densely fibrotic background punctuated by scattered atypical to pleomorphic spindle and multinucleated giant cells. Some of these tumors will have incorporated adipose tissue, although these adipocytic areas l...

journal_title：Journal of cutaneous pathology

authors： Al-Zaid T,Wang WL,Lopez-Terrada D,Lev D,Hornick JL,Hafeez Diwan A,Fletcher CD,Lazar AJ

更新日期：2013-04-01 00:00:00

abstract：:Cell adhesion between surfaces of cells and to extracellular matrices represents a fundamental mechanism in tissue organization and influences the biological behaviour and the architecture of tumors. We investigated the expression of various adhesion molecules in normal skin (n=5), nevi (n=29), and malignant melanoma ...

journal_title：Journal of cutaneous pathology

authors： Tronnier M,Alexander M,Wolff HH

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Considerable controversy has surrounded the question of possible biological responses to electromagnetic fields (EMFs) generated from visual display terminals (VDTs), such as personal computers (PCs) and ordinary television sets (TVs). The cellular and molecular mechanisms for such potential harmful health h...

journal_title：Journal of cutaneous pathology

authors： Johansson O,Gangi S,Liang Y,Yoshimura K,Jing C,Liu PY

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Despite its occasional unavailability, alcian blue has long been the stain of choice for the pathognomonic mucin-secreting cells of extramammary Paget's disease. Zirconyl hematoxylin is a recently developed substitute for alcian blue, which is made from common laboratory materials. METHODS:We have stained s...

journal_title：Journal of cutaneous pathology

authors： Smith AA,Silver TM

更新日期：2003-07-01 00:00:00

abstract：:Amyloidosis cutis dyschromica represents a rare type of primary cutaneous amyloidosis with few reported cases worldwide. It is characterized by asymptomatic, generalized hyperpigmentation with intermingled hypopigmented macules without atrophy or telangiectasia. We report herein a 19-year-old female who developed this...

journal_title：Journal of cutaneous pathology

authors： Garg T,Chander R,Jabeen M,Barara M,Mittal K,Jain M,Puri V

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Plasmacytoid dendritic cells (PDC) play a pivotal role in the induction of autoimmune diseases and other skin diseases. The present study focuses on the distribution patterns of PDC in patients with cutaneous lupus erythematosus (LE) and Jessner's lymphocytic infiltrate (LI) of the skin and compares them wit...

journal_title：Journal of cutaneous pathology

authors： Tomasini D,Mentzel T,Hantschke M,Cerri A,Paredes B,Rütten A,Schärer L,Kutzner H

更新日期：2010-11-01 00:00:00