Histomorphologic and immunophenotypic analysis of fibrofolliculomas and trichodiscomas in Birt-Hogg-Dube syndrome and sporadic disease.

abstract：:A 48 year-old white male with basal cell nevus syndrome presented with a metastatic basal cell carcinoma with neuroendocrine features. The tumor manifested aggressive behavior, having deep local invasion and metastases to para-aortic lymph nodes and bone. Neuroendocrine differentiation has rarely been associated with ...

journal_title：Journal of cutaneous pathology

authors： Tawfik O,Casparian JM,Garrigues N,Smith S,Kestenbaum T,Chamberlin F,Khan QS

更新日期：1999-07-01 00:00:00

abstract：:Electron microscopy of lentigines was performed to study the pigmentation abnormality in two children with LEOPARD syndrome. Giant melanosomes similar to those seen in café-au-lait spots of neurofibromatosis and nevus spilus were found in a lentigine from one of our cases. Our results show that "spherical granular mel...

journal_title：Journal of cutaneous pathology

authors： Bhawan J,Purtilo DT,Riordan JA,Saxena VK,Edelstein L

更新日期：1976-01-01 00:00:00

abstract：:Serum amyloid P component (SAP) is present not only in all types of cutaneous amyloidosis, but also in the normal dermal elastic fibers as well as abnormal elastic fibers, such as elastotic degeneration of elastic fibers in actinic keratosis. It was previously postulated that the colloid substance in colloid milium is...

journal_title：Journal of cutaneous pathology

authors： Hashimoto K,Black M

更新日期：1985-04-01 00:00:00

abstract：:Amyloidosis cutis dyschromica represents a rare type of primary cutaneous amyloidosis with few reported cases worldwide. It is characterized by asymptomatic, generalized hyperpigmentation with intermingled hypopigmented macules without atrophy or telangiectasia. We report herein a 19-year-old female who developed this...

journal_title：Journal of cutaneous pathology

authors： Garg T,Chander R,Jabeen M,Barara M,Mittal K,Jain M,Puri V

更新日期：2011-10-01 00:00:00

abstract：:Thirty cases of poorly differentiated carcinomas of the skin were examined for the expression of vimentin. All cases expressed cytokeratins; in addition, 12 cases were positive for vimentin. These were all non-reactive with antibodies to S100 protein, HMB45 and desmin. The finding of vimentin in poorly differentiated ...

journal_title：Journal of cutaneous pathology

authors： Iyer PV,Leong AS

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:Diagnosis of autoantibody- and immune complex-induced skin diseases is primarily based on direct immunofluorescence (DIF) microscopy. DIF staining is usually performed manually and, therefore, is labor intensive. The quality of immunohistochemical results considerably depends on the experience of the person ...

journal_title：Journal of cutaneous pathology

authors： Lemcke S,Sokolowski S,Rieckhoff N,Buschtez M,Kaffka C,Winter-Keil A,Schaller C,Rottmann N,Sadik CD,Stöcker W,Zillikens D,Schmidt E

更新日期：2016-03-01 00:00:00

abstract：:Mycosis fungoides in palmoplantar localization (MFPP) is a rare variant of MF that is confined to the hands and feet. Patients commonly receive treatment over many years for suspected palmoplantar dermatitis before the diagnosis is made. Most MFPP patients remain at patch or plaque stage, and often respond to treatmen...

journal_title：Journal of cutaneous pathology

authors： Pham AK,Carter JB,Ratcliffe NR,Fuld AD,Lansigan F,Burnside NJ,Guill MA 3rd,Zug KA,Jarvis LA,LeBlanc RE

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is associated with an increased risk of a second malignancy. METHODS:We conducted a retrospective clinicopathologic review of 12 patients with CLL/SLL who developed a second lymphoma in the skin. Demographic data, clinical information, and hi...

journal_title：Journal of cutaneous pathology

authors： Liu YA,Finn AJ,Subtil A

更新日期：2021-01-07 00:00:00

abstract：BACKGROUND:To date, there has been no systematic investigation of the detailed histological features of prurigo nodularis (PN) in a large cohort of patients. METHODS:This retrospective study includes skin biopsies of 136 patients (63 males, 73 females; mean age: 58.38 years) with PN. RESULTS:Highly characteristic for...

journal_title：Journal of cutaneous pathology

authors： Weigelt N,Metze D,Ständer S

更新日期：2010-05-01 00:00:00

abstract：:Melanoma ex blue nevus (MEBN) is a rare, aggressive, and potentially lethal neoplasm. Distinguishing MEBN from an atypical cellular blue nevus can be very challenging. We report a diagnostically difficult case of MEBN with lymph node metastases, in which single nucleotide polymorphism array and fluorescence in situ hy...

journal_title：Journal of cutaneous pathology

authors： Castillo SA,Pham AK,Barton DT,Lefferts JA,Yan S,Bridge JA,Linos K

更新日期：2019-03-01 00:00:00

abstract：:We report a facial tumor that was proven to be a metastatic mesothelioma. The diagnosis was not established pre-mortem. The patient died shortly after the facial biopsy, and an autopsy revealed a large pleural-based mass which had the gross appearance typical of a mesothelioma. Electron microscopic examination of tiss...

journal_title：Journal of cutaneous pathology

authors： Dutt PL,Baxter JW,O'Malley FP,Glick AD,Page DL

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:Tumor-infiltrating lymphocytes (TILs) are considered to play an important role in the antitumoral immune response. The presence and percentage of CD8-positive tumor-infiltrating T cells have been shown to correlate with differentiation and prognosis in various neoplasms. The aim of this study was to determin...

journal_title：Journal of cutaneous pathology

authors： Kamarashev J,Schaerer L,Burg G,Schmid MH,Müller B,Kempf W

更新日期：2001-10-01 00:00:00

abstract：:Acquired perforating calcific collagenosis (APCC), which is characterized by the calcification of dermal collagen fibers with subsequent transepidermal elimination and perforation, is an extremely rare entity. Thus far, it has only been reported in a patient with direct contact exposure to calcium chloride. Here, we r...

journal_title：Journal of cutaneous pathology

authors： Wang FY,Ng CY,Wu J,Kuo KL,Chang YY,Kuo TT

更新日期：2019-01-01 00:00:00

abstract：AIM:Adnexal tumors with divergent lines of differentiation are uncommon. Herein, I report a hamartoma of the eyelid with follicular, sebaceous and apocrine differentiation that exhibited prominent melanin pigmentation. METHODS:A 63-year-old white woman had a nodule present on her left upper eyelid for 15 years. The no...

journal_title：Journal of cutaneous pathology

authors： Proia AD

更新日期：2007-11-01 00:00:00

abstract：:This report documents the case of a 64-year-old African-American female with new end-stage renal disease (ESRD), diagnosed with systemic lupus erythematosus (SLE) on renal biopsy and serologies including a positive ANA (>1:2560), positive anti-Sm antibodies, low titer anti-RNP antibodies, high titer anti-Ro antibodies...

journal_title：Journal of cutaneous pathology

authors： Goyal A,Jain M,Rehberg K,Goodman W,Gertner E

更新日期：2019-09-01 00:00:00

abstract：AIMS:The differential diagnosis of acral keratoses is broad. Encompassing a variety of infectious, heritable and degenerative disorders, emphasis upon the clinical setting and histologic subtlety are often required to arrive at the correct diagnosis. Herein, we report on a series of adult patients who presented with ag...

journal_title：Journal of cutaneous pathology

authors： Saeed S,Sagatys E,Morgan MB

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Neurothekeoma is a benign tumor of putative peripheral nerve sheath origin. It occurs in a myxoid (classic) variant, cellular variant, and intermediate (mixed) variant. Cellular neurothekeoma (CNT) usually involves the head and neck or extremities of young patients. Histologically, CNT can be confused with m...

journal_title：Journal of cutaneous pathology

authors： Fullen DR,Lowe L,Su LD

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:The early stages of follicular mycosis fungoides (FMF) have not been described previously in the literature. OBJECTIVE:Our goal was to better categorize the clinicopathologic features of early stages of FMF. METHODS:The clinical notes of patients with a diagnosis of FMF seen during the previous 5 years wer...

journal_title：Journal of cutaneous pathology

authors： Tomasini C,Kempf W,Novelli M,Fava P,Annessi G,Rongioletti F,Fierro MT,Quaglino P

更新日期：2015-03-01 00:00:00

abstract：:Malignant mesothelioma (MM) is an aggressive and invasive neoplasm primarily affecting the pleura, peritoneum and pericardium. While mesothelioma commonly metastasizes to visceral organs, it has rarely been documented to involve the skin and subcutaneous tissue. There is a paucity of reports of cutaneous metastatic me...

journal_title：Journal of cutaneous pathology

authors： Ward RE,Ali SA,Kuhar M

更新日期：2017-12-01 00:00:00

abstract：:Merkel cell carcinoma is occasionally associated with other types of cutaneous malignancies including squamous cell carcinoma, basal cell carcinoma and lentigo maligna. We report a case of Merkel cell carcinoma co-existent with sebaceous carcinoma in the right upper eyelid of a 61-year-old Japanese man. Histopathologi...

journal_title：Journal of cutaneous pathology

authors： Tanahashi J,Kashima K,Daa T,Yada N,Fujiwara S,Yokoyama S

更新日期：2009-09-01 00:00:00

abstract：:Ten patients with traumatic alopecia (trichotillomania) were being investigated histologically and, in five of them, hairs from the affected scalp area were plucked out for direct microscopic examination. Some histologic features appear to be specific markers for traumatic alopecia: empty hair ducts, plucked out hair ...

journal_title：Journal of cutaneous pathology

authors： Lachapelle JM,Pierard GE

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND:Among nonepithelial second neoplasms which are known to be induced by irradiation, rhabdomyosarcomas are extremely rare, and melanomas are infrequent. We report a high-grade sarcoma with rhabdomyoblastic differentiation, which appeared 30 years after megavoltage irradiation for an endometrial adenocarcinoma,...

journal_title：Journal of cutaneous pathology

authors： Miracco C,Materno M,De Santi MM,Pirtoli L,Ninfo V

更新日期：2000-09-01 00:00:00

abstract：:A malignant pilomatricoma is described in a dog. The primary tumor apparently developed in the metatarsal area where there were multiple intradermal skin nodules. Lymphatic invasion by tumor cells resulted in metastasis to the mammary glands, lymph nodes and lungs. The tumor is compared to the pilomatricoma in man whe...

journal_title：Journal of cutaneous pathology

authors： Goldschmidt MH,Thrall DE,Jeglum KA,Everett JI,Wood MG

更新日期：1981-10-01 00:00:00

abstract：BACKGROUND:The lack of highly specific clinical and histopathological criteria has contributed to the delay in diagnosis of subungual melanoma in situ in its early stages. METHODS:Eighteen cases of subungual melanoma in situ, the largest series reported to date, were analyzed to characterize the clinical and histopath...

journal_title：Journal of cutaneous pathology

authors： Park SW,Jang KT,Lee JH,Park JH,Kwon GY,Mun GH,Lee DY,Lee JB,Park KK

更新日期：2016-01-01 00:00:00

abstract：:A survey of conditions with mucinous deposits is given. The most important factors for their diagnosis are to consider these disorders and to stain the slides for proteoglycans or glycosaminoglycans; the most common routine techniques are the Giemsa and the Alcian-blue stain. More sophisticated methods allow different...

journal_title：Journal of cutaneous pathology

authors： Steigleder GK,Küchmeister B

更新日期：1985-06-01 00:00:00

abstract：:The term "nevoid malignant melanoma" (nevoid MM) is used here to describe rare nodular malignant melanomas that may escape detection in routine histological sections due to the lack of a prominent intraepidermal component, sharp lateral circumscription and evidence of partial maturation with descent in the dermis. Nev...

journal_title：Journal of cutaneous pathology

authors： McNutt NS,Urmacher C,Hakimian J,Hoss DM,Lugo J

更新日期：1995-12-01 00:00:00

abstract：:Fundamental to our understanding of skin diseases and their presentation is an understanding of the pattern of their development. When we have established the molecular basis of their development we will be in a much better position to control and treat such diseases. The homeobox genes are a family of regulatory prot...

journal_title：Journal of cutaneous pathology

authors： Brown WM,Stenn KS

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:p16 immunostaining has been used to aid and improve the histopathologic evaluation of equivocal cervical lesions with associated low-grade or high-grade dysplasia. However, the utility of p16 immunostaining in the diagnosis of atypical genital skin lesions remains debatable. METHODS:We conducted a cross-sec...

journal_title：Journal of cutaneous pathology

authors： Ezaldein H,Lott JP,McNiff JM,Hui P,Buza N,Ko CJ

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Rare cases of a non-bullous neutrophilic dermatosis occurring in patients with lupus erythematosus (LE) have been reported, often as the presenting manifestation of the disease. METHODS:We reviewed hematoxylin and eosin-stained slides and obtained clinical information from four additional patients, two of w...

journal_title：Journal of cutaneous pathology

authors： Gleason BC,Zembowicz A,Granter SR

更新日期：2006-11-01 00:00:00

abstract：:A case of an unusual benign apocrine hamartoma was studied by light microscopic, immunohistochemical, and electron microscopic methods. This tumor clinically showed a linear configuration and was located on the midline chest of a pubescent male. Microscopic studies revealed features of both a tubular apocrine adenoma ...

journal_title：Journal of cutaneous pathology

authors： Epstein BA,Argenyi ZB,Goldstein G,Whitaker D

更新日期：1990-02-01 00:00:00