Neuroendocrine differentiation of a metastatic basal cell carcinoma in a patient with basal cell nevus syndrome.

abstract：:Sebaceous gland neoplasms such as adenoma, epithelioma, and carcinoma are uncommon cutaneous tumors. Although sporadic, their occurrence is clinically significant because of their association with Muir-Torre syndrome (MTS). MTS is a rare autosomal dominant genodermatosis characterized by the occurrence of sebaceous gl...

journal_title：Journal of cutaneous pathology

authors： Abbas O,Mahalingam M

更新日期：2009-06-01 00:00:00

abstract：:Traditionally, melanoma has been considered by surgeons to be a highly lethal malignancy, always requiring a radical surgical approach for optimal chance of cure. Yet melanoma patients who are now being referred for treatment frequently have small early lesions, and surgeons should develop a flexible attitude about ma...

journal_title：Journal of cutaneous pathology

authors： Patterson WB

更新日期：1979-06-01 00:00:00

abstract：:A case of pigmented hidrocystoma of eccrine secretory coil is presented. A 47-year-old woman had developed a bluish black small nodule in the anterior portion of the labium minor a few years before entry. Microscopically, the cyst was lined by eosinophilic columnar epithelium with abundant brownish granules. There was...

journal_title：Journal of cutaneous pathology

authors： Kamishima T,Igarashi S,Takeuchi Y,Ito M,Fukuda T

更新日期：1999-03-01 00:00:00

abstract：:Human hair follicles (HF) and sebaceous glands (SG) were assessed for the presence and distribution of the cytochrome P-450-aromatase (AR) and 3B-hydroxysteroid dehydrogenase (3B-HSD) enzymes. Immunohistochemical methods were used to examine both enzymes in male and female human skin specimens at various ages and diff...

journal_title：Journal of cutaneous pathology

authors： Sawaya ME,Penneys NS

更新日期：1992-08-01 00:00:00

abstract：:Thirty cases of poorly differentiated carcinomas of the skin were examined for the expression of vimentin. All cases expressed cytokeratins; in addition, 12 cases were positive for vimentin. These were all non-reactive with antibodies to S100 protein, HMB45 and desmin. The finding of vimentin in poorly differentiated ...

journal_title：Journal of cutaneous pathology

authors： Iyer PV,Leong AS

更新日期：1992-02-01 00:00:00

abstract：:Mycosis fungoides in palmoplantar localization (MFPP) is a rare variant of MF that is confined to the hands and feet. Patients commonly receive treatment over many years for suspected palmoplantar dermatitis before the diagnosis is made. Most MFPP patients remain at patch or plaque stage, and often respond to treatmen...

journal_title：Journal of cutaneous pathology

authors： Pham AK,Carter JB,Ratcliffe NR,Fuld AD,Lansigan F,Burnside NJ,Guill MA 3rd,Zug KA,Jarvis LA,LeBlanc RE

更新日期：2018-06-01 00:00:00

abstract：:We describe a case of syringocystadenoma papilliferum (SCAP) with a unique histopathology. A 50-year-old Japanese woman presented with a pedunculated tumor in the pubic region. Histopathological examination showed that the tumor was composed of basaloid cell proliferation interconnecting from the epidermis to the derm...

journal_title：Journal of cutaneous pathology

authors： Kishibe M,Iwasaki T,Takahashi I,Ishida-Yamamoto A

更新日期：2018-12-01 00:00:00

abstract：:In lymph nodes, classical Hodgkin lymphoma can typically be distinguished from non-Hodgkin lymphoma (NHL) by the presence of Hodgkin and Reed-Sternberg cells that co-express CD30 and CD15. However, anaplastic large cell lymphoma (ALCL) and diffuse large B-cell lymphoma (DLBCL) can show identical features, and some cas...

journal_title：Journal of cutaneous pathology

authors： Cho RJ,McCalmont TH,Ai WZ,Fox LP,Treseler P,Pincus LB

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Ulceration and osteoclast-like giant cells are two pathological features uncommonly seen in dermatofibromas. To our knowledge, the presence of these features has not been previously described within the same lesion. METHODS:We report the clinical, histopathological and immunohistochemical findings of a 38-y...

journal_title：Journal of cutaneous pathology

authors： González-Vilas D,García-Gavín J,Ginarte M,Rodríguez-Blanco I,Toribio J

更新日期：2009-10-01 00:00:00

abstract：:Study of 18 patients with biopsy diagnoses of eosinophilic panniculitis revealed diverse patterns of systemic disease, including Wells' syndrome, vasculitis, atopy, and erythema nodosum as well as localized panniculitis. Significant associated diseases included psychiatric illness, 6 (drug dependency, 4); atopy, 5 (as...

journal_title：Journal of cutaneous pathology

authors： Winkelmann RK,Frigas E

更新日期：1986-02-01 00:00:00

abstract：:A case of reactive perforating collagenosis in an adult male patient with chronic renal failure. Pruritic, umbilicate papules, showing extrusion of collagen fibers through the epidermis were detected histopathologically. Electron microscopy showed absence of basal membrane beneath the perforation and collagen fibers w...

journal_title：Journal of cutaneous pathology

authors： Beck HI,Brandrup F,Hagdrup HK,Jensen NK,Starklint H

更新日期：1988-04-01 00:00:00

abstract：:Extraskeletal Ewing's sarcoma has been recognized as being histologically indistinguishable from Ewing's sarcoma of bone. Although the occurrence of extraosseous Ewing's sarcoma in deep soft tissues has been well described, such cutaneous lesions are rare. We report the clinical history, histopathologic findings, and ...

journal_title：Journal of cutaneous pathology

authors： Peters MS,Reiman HM,Muller SA

更新日期：1985-12-01 00:00:00

abstract：:Rare epithelial structures in benign nerve sheath tumors are almost always glandular in appearance. We describe a case of intraoral plexiform schwannoma with concurrent squamous epithelial hyperplasia. The lesion occurred as a pigmented nodule on the gingiva of a 35-year-old woman with no systemic involvement. Histolo...

journal_title：Journal of cutaneous pathology

authors： Ide F,Muramatsu T,Kikuchi K,Saito I,Kusama K

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Transepithelial elimination is a process by which dermal materials are expelled through an active epithelial-dermal connective tissue interaction. It has been described as a regular or sporadic occurrence in a variety of dermatologic conditions, including sarcoidosis. OBSERVATION:Our patient demonstrated a ...

journal_title：Journal of cutaneous pathology

authors： Ismail A,Beckum K,McKay K

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The Wnt signaling pathway has been implicated in the pathogenesis of pilomatrical tumors. Lymphoid enhancer-binding factor 1 (LEF-1) is a downstream component of this pathway, and Caudal-related homeobox transcription factor 2 (CDX2) has been postulated to regulate it, but little is known about expression of...

journal_title：Journal of cutaneous pathology

authors： Tumminello K,Hosler GA

更新日期：2018-05-01 00:00:00

abstract：:Erythrodermic cutaneous T-cell lymphoma (E-CTCL) is the cause of less than 5% of all cases of generalized erythroderma. A methodical evaluation of skin, blood, and lymph node samples using standard histology, immunohistochemistry (IHC), flow cytometry (FC), and molecular analysis for evidence of a dominant T-cell clon...

journal_title：Journal of cutaneous pathology

authors： Vonderheid EC

更新日期：2006-02-01 00:00:00

abstract：:While some unequivocally benign infiltrates are easy to distinguish from cutaneous T-cell lymphoma (CTCL), drug-associated lymphomatoid hypersensitivity reaction and cutaneous lesions of collagen vascular disease can show cytologic atypia, clonality and an immunophenotypic profile that closely simulates CTCL and cause...

journal_title：Journal of cutaneous pathology

authors： Plaza JA,Morrison C,Magro CM

更新日期：2008-04-01 00:00:00

abstract：:Until recently the number of patients with syphilis has been diminishing. Although that trend has reversed cases of tertiary syphilis are rare and often difficult to diagnose as a substantial number of patients will have a negative rapid plasma reagin. Histologically, cutaneous lesions in late stage syphilis exist in ...

journal_title：Journal of cutaneous pathology

authors： Boyd AS

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Telomerase plays a role in the immortalization of cells and carcinogenesis. Previous studies have yielded conflicting results on whether human telomerase RNA (hTER) expression differs in nevi, atypical nevi and melanomas using polymerase chain reaction-based telomeric repeat amplification protocol or in situ...

journal_title：Journal of cutaneous pathology

authors： Fullen DR,Zhu W,Thomas D,Su LD

更新日期：2005-11-01 00:00:00

abstract：:Traditionally, the pigmented purpuric eruptions (PPE) have been subdivided into four histologic categories, based upon variations in histologic pattern and clinical morphologies. In recent years, it has become apparent that the lesions behave similarly, and this family of eruptions has become grouped under the term PP...

journal_title：Journal of cutaneous pathology

authors： Smoller BR,Kamel OW

更新日期：1991-12-01 00:00:00

abstract：:Perifollicular fibroma is a cutaneous hamartomatous proliferation of the pilar connective tissue sheath. We describe a patient with multiple perifollicular fibromas and analyze the literature on this topic. Histologically, perifollicular fibroma is characterized by a concentric arrangement of collagen fibers surroundi...

journal_title：Journal of cutaneous pathology

authors： Junkins-Hopkins JM,Cooper PH

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:The importance of changes in the supporting tumor stroma for cancer initiation and progression is well established. The characteristics of an activated tumor stroma, however, are not completely understood. In an effort to better characterize the desmoplastic response to human skin tumors, we evaluated the ex...

journal_title：Journal of cutaneous pathology

authors： Huber MA,Kraut N,Schweifer N,Dolznig H,Peter RU,Schubert RD,Scharffetter-Kochanek K,Pehamberger H,Garin-Chesa P

更新日期：2006-02-01 00:00:00

abstract：:Two patients with solitary lesions of pagetoid reticulosis are presented. A third case with disseminated lesions and similar microscopic detail is also reported. Lighg microscopic findings include an abnornal cell infiltrate confined to the epidermis and distributed diffusely in a pagetoid pattern. In ultrathin sectio...

journal_title：Journal of cutaneous pathology

authors： Wood WS,Killby VA,Stewart WD

更新日期：1979-04-01 00:00:00

abstract：:Post-vaccinial non-viral folliculitis has been recognized in the past decade as a new adverse cutaneous reaction to smallpox vaccination. Contrary to more serious smallpox vaccine reactions, post-vaccinial non-viral folliculitis has a benign course and resolves spontaneously within approximately 7 days. We describe ad...

journal_title：Journal of cutaneous pathology

authors： Bunick CG,Mariwalla K,Ibrahim O,Modi B,Imaeda S,McNiff JM

更新日期：2013-03-01 00:00:00

abstract：INTRODUCTION:Granulomatous mycosis fungoides (MF) is a rare variant in which granulomas are associated with other typical signs of MF. Its prognosis is worse than that of classical MF. Plasmacytoid dendritic cells (PDCs) are a subset of interferon-producing dendritic cells that link the innate and the adaptative immune...

journal_title：Journal of cutaneous pathology

authors： Fernandez-Flores A,Cassarino DS

更新日期：2019-05-01 00:00:00

abstract：:The lymphocytic subtypes effecting allogeneic graft-versus-host disease (GVHD) are unknown. We studied 35 skin biopsy specimens from 19 women transplanted with bone marrow from men for patterns and time course of infiltration of the skin by Y chromosome-bearing lymphocytes using in situ hybridization. Immunophenotypic...

journal_title：Journal of cutaneous pathology

authors： Horn TD,Haskell J

更新日期：1998-04-01 00:00:00

abstract：:Sarcoidosis is a granulomatous condition with diverse clinical presentations, including neurological findings. It was previously hypothesized that perineural sarcoidal granulomas in the skin may be an explanation of small-fiber neuropathy. Herein, we present a case of a 55 year old female with anesthetic cutaneous les...

journal_title：Journal of cutaneous pathology

authors： Kazi R,Kazlouskaya V,Ho J,Karunamurthy A

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Papillomatous stoma-related skin lesions may result from irritant reactions or infection with epidermodysplasia verruciformis human papillomavirus (HPV) types. METHODS:We report upon a papillomatous lesion at the ileostoma of a 63-year-old male with familial adenomatous polyposis and colorectal adenocarcino...

journal_title：Journal of cutaneous pathology

authors： Williams CM,Wieland U,Rodning CB,Horenstein MG

更新日期：2003-04-01 00:00:00

abstract：:Alpha-1 anti-trypsin (A1AT) deficiency is an inherited enzyme deficiency that manifests with fatal lung and liver complications. In addition to pulmonary and hepatic involvement, the disease has also been linked to an increased incidence of vasculitic syndromes and autoimmune diseases, including Wegener's granulomatos...

journal_title：Journal of cutaneous pathology

authors： Patterson CC,Ross P Jr,Pope-Harman AL,Knight DA,Magro CM

更新日期：2005-04-01 00:00:00

abstract：:Three selected cases of transient acantholytic dermatosis were studied because of their definitive correlation with sweating due to fever and/ or bed-ridden situations. Biopsy specimens were serially sectioned and acantholysis was found in the acrosyringium or traced to connect to the acrosyringium in all biopsy speci...

journal_title：Journal of cutaneous pathology

authors： Hashimoto K,Moiin A,Chang MW,Tada J

更新日期：1996-04-01 00:00:00