Eosinophilic panniculitis: a clinicopathologic study.

Abstract:

:Study of 18 patients with biopsy diagnoses of eosinophilic panniculitis revealed diverse patterns of systemic disease, including Wells' syndrome, vasculitis, atopy, and erythema nodosum as well as localized panniculitis. Significant associated diseases included psychiatric illness, 6 (drug dependency, 4); atopy, 5 (asthma, 3); malignancies, 5; immune complex vasculitis, 4; thyroid disease, 2; Wells' eosinophilic cellulitis, 2; glomerulonephritis and sarcoidosis, 1 each. The skin lesions varied from urticarial papules and plaques to purpura, pustules, and ulcerative lesions but always included a nodular subcutaneous component, frequently as a presenting complaint. Eosinophilic panniculitis is a non-specific finding that can signify localized disease, such as an insect bite or injection lipophagic granuloma in a drug-dependent patient, or systemic lymphoma or immune reactive disease. Eosinophilic panniculitis in erythema nodosum is perhaps its most confusing presentation.

journal_name

J Cutan Pathol

authors

Winkelmann RK,Frigas E

doi

10.1111/j.1600-0560.1986.tb00455.x

subject

Has Abstract

pub_date

1986-02-01 00:00:00

pages

1-12

issue

1

eissn

0303-6987

issn

1600-0560

journal_volume

13

pub_type

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