Cutaneous mucinous deposits.

abstract：BACKGROUND:Among the pigmented lesions with a central area of scar, we found a group of cases histologically characterized by striking architectural alteration of the melanocytic component, but with no cytological atypia and mitotically quiescent. The aim of the current study was to assess the biological nature of such...

journal_title：Journal of cutaneous pathology

authors： Fabrizi G,Pennacchia I,Pagliarello C,Massi G

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Morphea (localized scleroderma) and eosinophilic fasciitis (EF) are rare fibrosing disorders which may present a diagnostic challenge. While histopathologic features are often distinct, in some cases there may be overlap. T-cells contribute to etiopathogenesis of both autoimmune conditions. We sought to dete...

journal_title：Journal of cutaneous pathology

authors： Moy AP,Maryamchik E,Nikolskaia OV,Nazarian RM

更新日期：2017-06-01 00:00:00

abstract：:The diagnosis of a CD30+ cutaneous infiltrate is often difficult and requires clinicopathologic correlation. To further evaluate this challenge, initial clinical and histopathologic diagnoses were correlated with final clinicopathologic diagnosis in 44 cases with CD30 immunopositivity. Dermatopathologic evaluation con...

journal_title：Journal of cutaneous pathology

authors： De Souza A,Carter JB,Harris NL,Ferry JA,Duncan LM

更新日期：2015-07-01 00:00:00

abstract：:Three selected cases of transient acantholytic dermatosis were studied because of their definitive correlation with sweating due to fever and/ or bed-ridden situations. Biopsy specimens were serially sectioned and acantholysis was found in the acrosyringium or traced to connect to the acrosyringium in all biopsy speci...

journal_title：Journal of cutaneous pathology

authors： Hashimoto K,Moiin A,Chang MW,Tada J

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:BRAF inhibition has improved overall survival in patients with BRAF mutant melanoma, but this is associated with a range of known and predictable cutaneous side effects, including squamous cell carcinomas associated with RAS mutations. METHODS:We identified three severely dysplastic nevi, one atypical intra...

journal_title：Journal of cutaneous pathology

authors： Parekh V,Sobanko J,Miller CJ,Karakousis G,Xu W,Letrero R,Elenitsas R,Xu X,Elder DE,Amaravadi R,Schuchter LM,Nathanson KL,Wilson MA,Chu EY

更新日期：2019-03-01 00:00:00

abstract：:Many patients who present with patch and early plaque stage mycosis fungoides follow an indolent course and survive for many years following diagnosis. A certain subset of patients, however, have rapidly progressive disease leading to accelerated demise. We examined 21 histologic sections from initial biopsies taken f...

journal_title：Journal of cutaneous pathology

authors： Smoller BR,Detwiler SP,Kohler S,Hoppe RT,Kim YH

更新日期：1998-07-01 00:00:00

abstract：:Sinonasal non-keratinizing squamous cell carcinoma (SCC), previously designated as transitional cell carcinoma or cylindrical cell carcinoma, is an uncommon malignant neoplasm with distinct histopathological features, considered to be a low-grade malignancy that usually occurs in elderly patients. Extensive local inva...

journal_title：Journal of cutaneous pathology

authors： Guo R,Metcalf S,Crowson AN

更新日期：2012-08-01 00:00:00

abstract：:Primary cutaneous extranodal marginal zone lymphoma (MZL) of mucosa-associated lymphoid tissue (MALT) represents a monoclonal B-cell neoplasm that typically presents with papules, plaques or nodules. We describe a patient with a primary cutaneous MALT lymphoma with unusual clinical features and an unusual immunophenot...

journal_title：Journal of cutaneous pathology

authors： Edinger JT,Lorenzo CR,Breneman DL,Swerdlow SH

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Considerable controversy has surrounded the question of possible biological responses to electromagnetic fields (EMFs) generated from visual display terminals (VDTs), such as personal computers (PCs) and ordinary television sets (TVs). The cellular and molecular mechanisms for such potential harmful health h...

journal_title：Journal of cutaneous pathology

authors： Johansson O,Gangi S,Liang Y,Yoshimura K,Jing C,Liu PY

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Nickel can induce cellular and nuclear damages responsible for chronic diseases, like allergic contact dermatitis (ACD). We previously showed that matrix metalloproteinase-2 (MMP-2) gene expression was induced by nickel in nontumorigenic human keratinocytes cell line (HaCat). OBJECTIVE:To investigate the si...

journal_title：Journal of cutaneous pathology

authors： Perfetto B,Lamberti M,Giuliano MT,Canozo N,Cammarota M,Baroni A

更新日期：2007-06-01 00:00:00

abstract：:Immunotherapies targeting cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) and the programmed cell death 1 (PD-1) receptor and its ligand (PD-L1) have showed substantial therapeutic benefit in patients with clinically advanced solid malignancies. However, autoimmune toxicities are common and often significant adve...

journal_title：Journal of cutaneous pathology

authors： Tetzlaff MT,Jazaeri AA,Torres-Cabala CA,Korivi BR,Landon GA,Nagarajan P,Choksi A,Chen L,Uemura M,Aung PP,Diab A,Sharma P,Davies MA,Amaria R,Prieto VG,Curry JL

更新日期：2017-12-01 00:00:00

abstract：:Two cases of tubular apocrine adenoma were studied by light, histochemical, and electron microscopic methods. This benign apocrine hamartoma must be considered in the classification of appendage tumors, particularly those associated with organoid epithelial nevus, and may be confused with metastatic adenocarcinoma. Th...

journal_title：Journal of cutaneous pathology

authors： Umbert P,Winkelmann RK

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:p53 mutations are etiologically associated with the development of squamous cell carcinomas (SCCs) or with exposure to specific carcinogens. The study was conducted to examine the relationship of immunohistochemistry (IHC) scores between altered p53 protein expression in relation to patient's habits and hist...

journal_title：Journal of cutaneous pathology

authors： Bukhari MH,Niazi S,Chaudhry NA

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Telomerase plays a role in the immortalization of cells and carcinogenesis. Previous studies have yielded conflicting results on whether human telomerase RNA (hTER) expression differs in nevi, atypical nevi and melanomas using polymerase chain reaction-based telomeric repeat amplification protocol or in situ...

journal_title：Journal of cutaneous pathology

authors： Fullen DR,Zhu W,Thomas D,Su LD

更新日期：2005-11-01 00:00:00

abstract：:Free-living amebae are ubiquitous in our environment, but rarely cause cutaneous infection. Balamuthia mandrillaris has a predilection for infecting skin of the central face. Infection may be restricted to the skin or associated with life-threatening central nervous system (CNS) involvement. We report a case of a 91-y...

journal_title：Journal of cutaneous pathology

authors： Chang OH,Liu F,Knopp E,Muehlenbachs A,Cope JR,Ali I,Thompson R,George E

更新日期：2016-10-01 00:00:00

abstract：:Epithelioid cells with foamy cytoplasm (histiocytoid features) are typical histopathologic findings among benign and malignant histiocytic neoplasms such as xanthoma and atypical fibroxanthoma. However, these changes are unusual in melanoma, which is typically composed of nested and variably pigmented atypical epithel...

journal_title：Journal of cutaneous pathology

authors： Farah M,Nagarajan P,Torres-Cabala CA,Curry JL,Amaria RN,Wargo J,Tawbi H,Ivan D,Prieto VG,Tetzlaff MT,Aung PP

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:Long-term preservation of immunofluorescence is important for re-examinations. We investigated whether the storage of direct immunofluorescent (DIF)-positive slides at room temperature was reliable in daily practice. METHODS:One hundred and twenty-five DIF-positive slides from the skin of 52 patients were e...

journal_title：Journal of cutaneous pathology

authors： Dikicioglu E,Meteoglu I,Okyay P,Culhaci N,Kacar F

更新日期：2003-08-01 00:00:00

abstract：:Linear dermatoses are fascinating entities that likely reflect embryologically derived cutaneous mosaicism, even when they occur after childhood. Adult blaschkitis is a rare, relapsing inflammatory dermatitis that most often presents in middle age. It presents clinically as a pruritic eruption of linear papules, vesic...

journal_title：Journal of cutaneous pathology

authors： Johnson M,Walker D,Galloway W,Gardner JM,Shalin SC

更新日期：2014-12-01 00:00:00

abstract：:We report a 2-year-old girl with developmental delay who, from the age of 1 year, developed perniotic lesions of the hands and feet initially diagnosed as chilblain lupus. Histological examination showed features of epidermal necrosis with intraepidermal bulla formation, interface dermatitis, lymphocytic vasculitis wi...

journal_title：Journal of cutaneous pathology

authors： Kolivras A,Aeby A,Crow YJ,Rice GI,Sass U,André J

更新日期：2008-08-01 00:00:00

abstract：:Large cell acanthoma (LCA) is an epidermal neoplasm whose nature has been variously explained. Though frequently hyperpigmented, we describe for the first time an achromic case located on the dorsum of the right hand of a 83-year-old woman. This observation is largely inconsistent with one of the theories about the na...

journal_title：Journal of cutaneous pathology

authors： Ambrojo P,Aguilar A,Requena L,Sánchez Yus E

更新日期：1990-06-01 00:00:00

abstract：:Nm23 is a gene with a putative metastasis-suppressor function, whose expression is inversely correlated with the metastatic potential of some solid malignancies. Because very few data exist concerning the role of nm23 in skin tumors, we studied the immunohistochemical expression of nm23 gene product in frozen sections...

journal_title：Journal of cutaneous pathology

authors： Kanitakis J,Euvrard S,Bourchany D,Faure M,Claudy A

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:A reduction in the expression of the pan T-cell markers CD7 and CD62L supports an endogenous T-cell dyscrasia. Previously, clone availability for CD62L restricted its application to frozen tissue sections. MATERIALS AND METHODS:A nonavidin/biotin technique to examine CD3, CD62L, and CD7 in paraffin formalin...

journal_title：Journal of cutaneous pathology

authors： Magro CM,Sachdeva MP,Crowson AN,Barusevicius A,Baran PN,Kovatich AJ

更新日期：2005-01-01 00:00:00

abstract：:Pigmented extramammary Paget disease (PEMPD) is a rare intraepithelial carcinoma which can clinically resemble other pigmented neoplasms. Similarities to melanoma on dermoscopy, histopathology, and reflectance confocal microscopy (RCM) increase the risk of misdiagnosis and, consequently, mismanagement. Here, we descri...

journal_title：Journal of cutaneous pathology

authors： Chuchvara N,Reilly C,Haroon A,Wassef C,Maghari A,Rao B

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Hypertrophic lichen planus (LP) is a variant of LP favoring the lower extremities and showing prominent epidermal hyperplasia and hyperorthokeratosis. Contrary to dogma that eosinophils are rare in LP and variants, we noticed that some cases of hypertrophic LP have eosinophils in the absence of drug history....

journal_title：Journal of cutaneous pathology

authors： Alomari A,McNiff JM

更新日期：2014-04-01 00:00:00

abstract：:While some unequivocally benign infiltrates are easy to distinguish from cutaneous T-cell lymphoma (CTCL), drug-associated lymphomatoid hypersensitivity reaction and cutaneous lesions of collagen vascular disease can show cytologic atypia, clonality and an immunophenotypic profile that closely simulates CTCL and cause...

journal_title：Journal of cutaneous pathology

authors： Plaza JA,Morrison C,Magro CM

更新日期：2008-04-01 00:00:00

abstract：BACKGROUND:Changes in the clinical appearance of benign dermal nevi during pregnancy may be concerning for malignant transformation. Because the hormonal milieu of pregnancy has not proven to alter their banal behavior, histologic characterization is needed to prevent over-diagnosis and unnecessary treatment. METHODS:...

journal_title：Journal of cutaneous pathology

authors： Chan MP,Chan MM,Tahan SR

更新日期：2010-08-01 00:00:00

abstract：:Since the first demonstration of skin antibodies in sera of pemphigus patients by IF (Beutner & Jordon 1964), the scope of skin diseases in which immunologic findings may be of interest has enormously enlarged and dermatology remains one of the leading clinical specialities applying IHC in both diagnosis and research....

journal_title：Journal of cutaneous pathology

authors： Thivolet J,Faure M

更新日期：1983-02-01 00:00:00

abstract：:Mucinous cutaneous adnexal tumors are an uncommon occurrence. We describe three cases of mucinous hidradenoma characterized by diffuse and prominent mucinous cell proliferation and discuss the relevant literature. The patients (two men and one woman) ranged in age from 32 to 72 years. The lesions were completely excis...

journal_title：Journal of cutaneous pathology

authors： Goh SG,Carr R,Dayrit JF,Calonje E

更新日期：2007-06-01 00:00:00

abstract：:Clinical and histologic features of 44 invasive squamous cell carcinomas of the lip treated by surgical excision were correlated with metastases and survival. Age, diameter, ulceration, grade, depth of invasion, muscle invasion, mitotic rate, lymphatic-vascular invasion, and tumor infiltrating lymphocytes were evaluat...

journal_title：Journal of cutaneous pathology

authors： Stein AL,Tahan SR

更新日期：1994-02-01 00:00:00

abstract：:Lesions of seborrheic keratoses were studied by scanning electrom microscopy. Numerous yeasts were present on the karatinized cells and hairs associated with the lesions. Surfaces of some yeasts were smooth and others were ruffled. The ruffles suggested the presence of a glycocalyx. The yeasts exhibited the morphologi...

journal_title：Journal of cutaneous pathology

authors： Wilborn WH,Montes LF

更新日期：1980-02-01 00:00:00