Abstract:
:Two young patients with conjunctival compound nevi are presented to illustrate two types of abnormalities that lead to difficulty in distinction of these nevi from invasive melanomas. In Case 1, inflammation is associated with disruption of the nevus cell architecture and cytologic atypia. In Case 2, the occurrence of a combined nevus (compound and blue nevus types) in the conjunctiva leads to diagnostic problems. Circumscription of the lesions, lack of mitoses in the substantia propria, and lack of pagetoid spread of atypical cells in the adjacent conjunctival epithelium support benign diagnoses in both cases.
journal_name
J Cutan Patholjournal_title
Journal of cutaneous pathologyauthors
Kabukçuoğlu S,McNutt NSdoi
10.1111/j.1600-0560.1999.tb01838.xkeywords:
subject
Has Abstractpub_date
1999-05-01 00:00:00pages
248-52issue
5eissn
0303-6987issn
1600-0560journal_volume
26pub_type
杂志文章abstract::Two cases of juvenile elastoma (nevus elasticus in disseminated tumors) were histologically and ultrastructurally investigated. The predominant components of this disseminated dysembryoplasia are abnormal elastic fibers. Both cases showed numerous large elastic fibers with an abundant background matrix. The elastic mi...
journal_title:Journal of cutaneous pathology
pub_type: 杂志文章
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更新日期:1981-06-01 00:00:00
abstract::Angioimmunoblastic T-cell lymphoma (AITL) is an aggressive form of peripheral T-cell lymphoma, characterized by systemic symptoms, diffuse lymphadenopathy, hepatosplenomegaly and immunodysregulation. Half of AITL is associated with cutaneous symptoms, but only few cases with bullous eruption have been described. Assoc...
journal_title:Journal of cutaneous pathology
pub_type: 杂志文章,评审
doi:10.1111/cup.13576
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:Becker nevus (BN) is a unilateral, hairy, pigmented cutaneous hamartoma that frequently appears in adolescence. Several features of BN suggest that increased androgen sensitivity plays a role in its pathogenesis. There have been only a few studies of histopathologic and immunohistochemical characteristics of...
journal_title:Journal of cutaneous pathology
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更新日期:2008-12-01 00:00:00
abstract::Cutaneous mixed tumors (MTs), also known as chondroid syringomas, usually arise as small nodules in the head and neck region. We describe an unusual case of a giant MT measuring 9 cm in its greatest diameter, occurring as a slowly growing pedunculated mass on the breast of a 74-year-old woman. Although MT may rarely o...
journal_title:Journal of cutaneous pathology
pub_type: 杂志文章
doi:10.1111/j.1600-0560.2008.01104.x
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:Epidermal nevi (in the broad sense of epithelial nevi) may give rise to benign or malignant skin tumors. They may also be associated with anomalies of other organ systems in an epidermal nevus syndrome. RESULTS:This article describes a preterm infant with nevus sebaceus of the scalp and face, a large turban...
journal_title:Journal of cutaneous pathology
pub_type: 杂志文章
doi:10.1034/j.1600-0560.2003.00112.x
更新日期:2003-10-01 00:00:00
abstract::The advent of immunoperoxidase technique on paraffin embedded tissue has identified a number of shared immunologic markers present in various lymphoproliferative cutaneous disorders. Two such disorders are the recently described primary cutaneous CD30-positive anaplastic large cell lymphoma (ALCL) and lymphomatoid pap...
journal_title:Journal of cutaneous pathology
pub_type: 杂志文章
doi:10.1111/j.1600-0560.1995.tb01413.x
更新日期:1995-08-01 00:00:00
abstract::The distribution of desmoglein, plakoglobin, E-cadherin, and beta-catenin in the peri-lesional and lesional skin of Hailey-Hailey disease, Darier's disease, and pemphigus vulgaris was examined by immunoelectron microscopy. In the peri-lesional skin, the immunolabeling of these desmosomal components was localized to de...
journal_title:Journal of cutaneous pathology
pub_type: 杂志文章
doi:10.1111/j.1600-0560.1998.tb01698.x
更新日期:1998-02-01 00:00:00
abstract::Cutaneous CD30+ lymphoid infiltrates appear cytologically atypical and occasionally may be misinterpreted as recurrent disease when they occur in patients treated for other primary hematologic malignancies. We recently encountered two such cases and present our findings. One patient with B-cell lymphoma and another wi...
journal_title:Journal of cutaneous pathology
pub_type: 杂志文章
doi:10.1034/j.1600-0560.2000.027005249.x
更新日期:2000-05-01 00:00:00
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更新日期:2005-09-01 00:00:00
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journal_title:Journal of cutaneous pathology
pub_type: 杂志文章
doi:10.1111/j.1600-0560.1980.tb00975.x
更新日期:1980-02-01 00:00:00
abstract::Mycosis fungoides (MF) is a rare type of non-Hodgkin's lymphoma affecting the skin. Because MF develops slowly over several years and may have a variety of clinical presentations, including itchy patches, plaques or tumors that may be confused with common benign conditions such as eczema and psoriasis, the disease pre...
journal_title:Journal of cutaneous pathology
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0560.2006.00662.x
更新日期:2007-07-01 00:00:00
abstract::Immunotherapies targeting cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) and the programmed cell death 1 (PD-1) receptor and its ligand (PD-L1) have showed substantial therapeutic benefit in patients with clinically advanced solid malignancies. However, autoimmune toxicities are common and often significant adve...
journal_title:Journal of cutaneous pathology
pub_type:
doi:10.1111/cup.13044
更新日期:2017-12-01 00:00:00
abstract:BACKGROUND:The cell origin of dermatofibroma (DF) has not been clarified satisfactorily. This study was undertaken to assess the distribution of fibroblasts and the relationship between fibroblasts and other constituent cells in DF by 47-kDa heat-shock protein (HSP47), a cell marker for skin fibroblast. METHODS:Immuno...
journal_title:Journal of cutaneous pathology
pub_type: 杂志文章
doi:10.1111/j.1600-0560.2007.00768.x
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Chronic graft-vs.-host disease (GVHD) is a severe and potentially fatal complication in patients after undergoing allogeneic stem cell transplant. This disease may be hard to diagnose as it has numerous cutaneous presentations. METHODS:We report four cases of patients seen at Stanford Hospital between Janua...
journal_title:Journal of cutaneous pathology
pub_type: 杂志文章
doi:10.1111/cup.12640
更新日期:2016-03-01 00:00:00
abstract::Palisaded encapsulated neuroma (PEN; solitary circumscribed neuroma) is a benign, morphologically characteristic cutaneous or mucosal neuroma. Most are solitary lesions on the face, neck or oral mucosa. Histologically, the majority appears as dermal nodules of Schwann cell-rich fascicles, with or without distinctive e...
journal_title:Journal of cutaneous pathology
pub_type: 杂志文章
doi:10.1111/j.1600-0560.2009.01380.x
更新日期:2010-01-01 00:00:00
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journal_title:Journal of cutaneous pathology
pub_type: 杂志文章,随机对照试验
doi:10.1111/cup.12186
更新日期:2013-09-01 00:00:00
abstract::We first report a case of granular cell histiocytosis occurring as a solitary polypoid lesion of the nipple in a 15-year-old girl. Histologically, the lesion was composed of a dermal population of medium- to large-sized, short spindle- to round- to epithelioid-shaped cells with eosinophilic cytoplasm containing numero...
journal_title:Journal of cutaneous pathology
pub_type: 杂志文章
doi:10.1111/j.1600-0560.2009.01305.x
更新日期:2010-02-01 00:00:00
abstract:BACKGROUND:Latent infection by human papillomavirus (HPV) has been described for genital (mucosal) and epidermodysplasia verruciformis subtypes. Only rarely has cutaneotropic, non-oncogenic HPV been found by polymerase chain reaction studies in normal skin. METHODS:We noted myrmecia wart inclusions as an incidental hi...
journal_title:Journal of cutaneous pathology
pub_type: 杂志文章
doi:10.1111/j.1600-0560.2012.01968.x
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:Genital basal cell carcinoma (BCC) accounts for <1% of all BCCs. We aimed to elucidate the pathogenesis of genital BCC. METHODS:We retrospectively evaluated cases of pathologically diagnosed genital BCC between 1990 and 2016 in an Asian tertiary referral center. The control group was composed of consecutive...
journal_title:Journal of cutaneous pathology
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journal_title:Journal of cutaneous pathology
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更新日期:2014-04-01 00:00:00
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journal_title:Journal of cutaneous pathology
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更新日期:1981-10-01 00:00:00
abstract::A 1-month-old female infant was seen in consultation because of a congenital subcutaneous nodule, 2 x 3 cm in diameter, in the right retroauricular area. The nodule was surgically excised. Histologically, a large subcutaneous nodular mass was well delimited but not encapsulated. It consisted of a monomorphous sheet of...
journal_title:Journal of cutaneous pathology
pub_type: 杂志文章,评审
doi:10.1111/j.1600-0560.1995.tb00763.x
更新日期:1995-10-01 00:00:00
abstract::After intradermal testing with goldsodiumthiomalate (GSTM), 5 out of 8 patients developed skin papules at the test sites, which persisted up to 20 months. The lesions were surgically excised. Histology revealed pseudolymphoma of B and T cell type containing follicular structures and occasional small granulomas. The am...
journal_title:Journal of cutaneous pathology
pub_type: 杂志文章
doi:10.1111/j.1600-0560.1996.tb01306.x
更新日期:1996-08-01 00:00:00
abstract::Dirofilaria repens (formerly Dirofilaria conjunctiva) is a natural parasite of the subcutaneous tissues of dogs, cats and wild carnivores in Europe, Africa and Asia. Microfilariae are transmitted to humans by various species of mosquito. An autochthonous case of subcutaneous dirofilariasis is reported in a Greek patie...
journal_title:Journal of cutaneous pathology
pub_type: 杂志文章
doi:10.1111/j.1600-0560.2008.01144.x
更新日期:2009-08-01 00:00:00
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journal_title:Journal of cutaneous pathology
pub_type: 杂志文章
doi:10.1034/j.1600-0560.2001.028009448.x
更新日期:2001-10-01 00:00:00
abstract::Cutaneous immune-related adverse events (irAEs) are a known consequence of immune checkpoint inhibitor (ICI) therapy and may exhibit a spectrum of morphologic features both clinically and histologically. Lichenoid dermatitis associated with ICI therapy (LD-ICI) is the most frequently encountered histopathologic type o...
journal_title:Journal of cutaneous pathology
pub_type: 临床试验,杂志文章
doi:10.1111/cup.13536
更新日期:2019-11-01 00:00:00
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journal_title:Journal of cutaneous pathology
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更新日期:2006-12-01 00:00:00
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journal_title:Journal of cutaneous pathology
pub_type: 杂志文章
doi:10.1111/j.1600-0560.1990.tb00079.x
更新日期:1990-06-01 00:00:00
abstract:BACKGROUND:Myxoid liposarcoma typically presents as a deep-seated mass in the lower extremity of adults. Presentation as a primary subcutaneous tumor is rare. Here we discuss clinicopathologic characteristics of three such cases and their differential diagnosis to alert dermatopathologists to this unusual clinical pres...
journal_title:Journal of cutaneous pathology
pub_type: 杂志文章
doi:10.1111/cup.12428
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:Pigmentation is a characteristic clinical feature of basal cell carcinomas (BCCs) in Japanese patients. The pathogenesis of melanin pigment in pigmented BCCs is poorly understood. METHODS:We have combined the techniques of morphometric analysis and electron microscopy to assess accurately the morphologic as...
journal_title:Journal of cutaneous pathology
pub_type: 杂志文章
doi:10.1034/j.1600-0560.2001.280104.x
更新日期:2001-01-01 00:00:00