Malignant transformation of eccrine tumors.

Abstract:

:Malignant transformation occurred in pre-existing sweat gland tumors in 7 patients. Three lesions showed an histologic pattern of eccrine spiradenoma, 2 eccrine poroma, one cylindroma and one papillary eccrine adenoma. Malignant transformation was histologically characterized by the presence of solid tumor areas populated with large cells having irregularly shaped nuclei and mitotic figures. There were multiple foci of squamous metaplasia, areas of loss of basement membrane and invasion of the surrounding connective tissue.

journal_name

J Cutan Pathol

authors

Galadari E,Mehregan AH,Lee KC

doi

10.1111/j.1600-0560.1987.tb00122.x

subject

Has Abstract

pub_date

1987-02-01 00:00:00

pages

15-22

issue

1

eissn

0303-6987

issn

1600-0560

journal_volume

14

pub_type

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