Cutaneous endometriosis: diagnostic immunohistochemistry and clinicopathologic correlation.

abstract：BACKGROUND:Transepithelial elimination is a process by which dermal materials are expelled through an active epithelial-dermal connective tissue interaction. It has been described as a regular or sporadic occurrence in a variety of dermatologic conditions, including sarcoidosis. OBSERVATION:Our patient demonstrated a ...

journal_title：Journal of cutaneous pathology

authors： Ismail A,Beckum K,McKay K

更新日期：2014-01-01 00:00:00

abstract：:Glomus tumors are rare, soft-tissue neoplasms arising from the thermoregulatory neuromyoarterial glomus bodies. They are commonly observed in the extremities and typically present with symptoms of cold hypersensitivity, pain and localized tenderness. Intraneural glomus tumors (INGTs) are even rarer. Here we review the...

journal_title：Journal of cutaneous pathology

authors： Muthiah S,Hussain R,Stefanos N,Husain A

更新日期：2018-04-01 00:00:00

abstract：:The three-dimensional morphology of six dermatofibromas was studied by scanning electron microscopy. Hypertrophic epidermal ridges covered with large keratinized cells overlay each dermal lesion. Small collagenous fibers in the tumors contrasted with the bundles of much larger collagenous fibers in the normal dermis p...

journal_title：Journal of cutaneous pathology

authors： Wilborn WH,Montes LF

更新日期：1979-08-01 00:00:00

abstract：:The histogenetic relationship amongst various dendritic cells of the dermis which may express markers including factor XIIIa (FXIIIa) or CD34 remains unclear. In this study we utilized a sensitive indirect immunoperoxidase staining technique to identify CD34 and FXIIIa, as well the monocyte/macrophage markers KP-1 and...

journal_title：Journal of cutaneous pathology

authors： Altman DA,Nickoloff BJ,Fivenson DP

更新日期：1993-04-01 00:00:00

abstract：AIM:Adnexal tumors with divergent lines of differentiation are uncommon. Herein, I report a hamartoma of the eyelid with follicular, sebaceous and apocrine differentiation that exhibited prominent melanin pigmentation. METHODS:A 63-year-old white woman had a nodule present on her left upper eyelid for 15 years. The no...

journal_title：Journal of cutaneous pathology

authors： Proia AD

更新日期：2007-11-01 00:00:00

abstract：:We studied the degenerative "ancient" changes in 19 cases of benign cutaneous schwannoma (BCS). Using conventional and immunohistochemical stains, we found (a) degenerative changes in 15 of 19 BCS; (b) prominent vascular abnormalities in 11 of 15 BCS; and (c) cytologic atypia in 15 of 19 BCS, without mitotic figures. ...

journal_title：Journal of cutaneous pathology

authors： Argenyi ZB,Balogh K,Abraham AA

更新日期：1993-04-01 00:00:00

abstract：:We examined the proliferative characteristics of 20 basal-cell carcinomas (BCCs) and 16 trichoepitheliomas (TEps) in an effort to understand and explore possible differences in their tumorigenic cell-cycle properties. These tumors were first compared for their expression of the nuclear proliferative protein Ki-67 and ...

journal_title：Journal of cutaneous pathology

authors： Lum CA,Binder SW

更新日期：2004-09-01 00:00:00

abstract：:We encountered a patient who complained of many small papules on the neck, shoulders, upper chest and upper back. Biopsy specimens showed complete loss of elastic fibers in the upper dermis including papillary dermis, whereas those of the mid dermis were intact. Electron microscopy revealed that assembly of component ...

journal_title：Journal of cutaneous pathology

authors： Hashimoto K,Tye MJ

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:BRCA1-associated protein 1 (BAP1) represents a recently identified tumor suppressor protein. Loss of BAP1 has been observed in cutaneous epithelioid Spitz tumors. These cutaneous melanocytic tumors show a distinct histopathologic phenotype characterized by an intradermal sheet-like proliferation of epithelio...

journal_title：Journal of cutaneous pathology

authors： Gammon B,Traczyk TN,Gerami P

更新日期：2013-06-01 00:00:00

abstract：:Pigmented extramammary Paget disease (PEMPD) is a rare intraepithelial carcinoma which can clinically resemble other pigmented neoplasms. Similarities to melanoma on dermoscopy, histopathology, and reflectance confocal microscopy (RCM) increase the risk of misdiagnosis and, consequently, mismanagement. Here, we descri...

journal_title：Journal of cutaneous pathology

authors： Chuchvara N,Reilly C,Haroon A,Wassef C,Maghari A,Rao B

更新日期：2020-12-01 00:00:00

abstract：:A case of basal cell carcinoma with "monster cells" is reported. Clinically, the lesion presented as a red nodule on the forearm of a 58-year-old male. The histologic picture was striking, with large, "monstrous" nuclei scattered throughout a well defined nodule. Basal cell carcinoma with monster cells appears to repr...

journal_title：Journal of cutaneous pathology

authors： Elston DM,Bergfeld WF,Petroff N

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:Co-lesional acquired immunodeficiency syndrome-associated cutaneous Kaposi sarcoma (AIDS-KS) and Mycobacterium tuberculosis-associated granulomatous inflammation are undocumented. METHOD:Retrospective appraisal of skin biopsies with co-lesional AIDS-KS and microscopic tuberculosis (TB). RESULTS:Sixteen bio...

journal_title：Journal of cutaneous pathology

authors： Ramdial PK,Sing Y,Subrayan S,Calonje E,Aboobaker J,Sydney C,Sookdeo D,Ramburan A,Madiba TE

更新日期：2010-08-01 00:00:00

abstract：:The bcl-2 proto-oncogene encodes a protein that protects cells from programmed cell death (apoptosis). High levels of this protein confer a growth advantage to neoplastic cells even in the absence of a high mitotic rate. This gene is involved in the interchromosomal 14;18 translocation, an abnormality present in more ...

journal_title：Journal of cutaneous pathology

authors： Cerroni L,Kerl H

更新日期：1994-10-01 00:00:00

abstract：:Cell adhesion between surfaces of cells and to extracellular matrices represents a fundamental mechanism in tissue organization and influences the biological behaviour and the architecture of tumors. We investigated the expression of various adhesion molecules in normal skin (n=5), nevi (n=29), and malignant melanoma ...

journal_title：Journal of cutaneous pathology

authors： Tronnier M,Alexander M,Wolff HH

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:Cryptococcosis and alternariosis are rare opportunistic infections often observed in immunocompromised patients. Because Cryptococcus and Alternaria are ubiquitous fungi found in soil, the presence of fungi in the dermis has to be observed on histological examination to confirm a real cutaneous, invasive, in...

journal_title：Journal of cutaneous pathology

authors： Courville P,Favennec L,Viacroze C,Barrel A,Young P,Abboud P,Thomine E,Metayer J,Nouvet G

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Melanoma staging has depended on depth of invasion (Breslow thickness, BT), mitotic rate (MR) and ulceration. In anticipation of the AJCC's eighth edition, variability in pathologists' assessment of these factors and consequently in tumor staging was assessed. METHODS:One-hundred and fifteen cases of invasi...

journal_title：Journal of cutaneous pathology

authors： Taylor L,Hood K,Reisch L,Elmore J,Piepkorn M,Barnhill R,Knezevich S,Radick A,Elder D

更新日期：2018-08-01 00:00:00

abstract：:Malignant mesothelioma (MM) is an aggressive and invasive neoplasm primarily affecting the pleura, peritoneum and pericardium. While mesothelioma commonly metastasizes to visceral organs, it has rarely been documented to involve the skin and subcutaneous tissue. There is a paucity of reports of cutaneous metastatic me...

journal_title：Journal of cutaneous pathology

authors： Ward RE,Ali SA,Kuhar M

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:The Wnt-signaling pathway, involving beta-catenin, apc, and axin, plays a critical role in numerous developmental events. Alterations in the Wnt-signaling pathway have been detected in a wide variety of neoplasms. However, similar aberrations have not been described in Merkel cell carcinoma (MCC). The aim of...

journal_title：Journal of cutaneous pathology

authors： Liu S,Daa T,Kashima K,Kondoh Y,Yokoyama S

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Alpha-methylacyl-CoA racemase (AMACR), also known as P504S, is a protein that plays an important role in mitochondrial and peroxisomal beta-oxidation of branched-chain fatty acid and bile acid intermediates. AMACR has been established as a valuable diagnostic marker for prostate cancer and has recently been ...

journal_title：Journal of cutaneous pathology

authors： Halsey MA,Calder KB,Mathew R,Schlauder S,Morgan MB

更新日期：2010-04-01 00:00:00

abstract：:We present a case of a 64-year-old man with refractory acute myeloid leukemia and trisomy 8 who developed leukemia cutis. Interphase fluorescence in situ hybridization (FISH) was performed on a paraffin-embedded skin section. FISH confirmed a population of cells with trisomy 8 in the blastic infiltrates involving the ...

journal_title：Journal of cutaneous pathology

authors： Shvartsbeyn M,Meehan SM,Gu P,Nierodzik ML,Perle MA

更新日期：2012-11-01 00:00:00

abstract：:Biologic therapies targeting tumor necrosis factor (TNF)-alpha have become a mainstay in the management of a number of autoimmune diseases. We report a series of adverse skin eruptions in six patients (four females, two males, age: 21-58 years, mean: 39) receiving 4 months to 10 years (mean 3.1 years) of anti-TNF-alph...

journal_title：Journal of cutaneous pathology

authors： Hawryluk EB,Linskey KR,Duncan LM,Nazarian RM

更新日期：2012-05-01 00:00:00

abstract：:Fifteen halo nevi were stained for the presence of S100 protein by an unlabelled antibody peroxidase-antiperoxidase method. S100 protein was clearly identifiable within nevus cell nests in the inflammatory infiltrate. The presence of this substance helped to identify nevus cells in dense inflammatory infiltrates and c...

journal_title：Journal of cutaneous pathology

authors： Penneys NS,Mayoral F,Barnhill R,Ziegels-Weissman J,Nadji M

更新日期：1985-02-01 00:00:00

abstract：:The plasma membrane ultrastructure of the extramammary Paget cells was characterized by freeze-fracture electron microscopy, which was first employed for the study of Paget cells. The Paget cell plasma membrane revealed a flat fractured plane with much fewer and smaller desmosome-particle aggregations than those of th...

journal_title：Journal of cutaneous pathology

authors： Kitajima Y,Mori S

更新日期：1980-12-01 00:00:00

abstract：:Desmoplastic trichoepithelioma (DTE) is a benign follicular tumor occurring most commonly within facial skin of young and middle-aged women, morphologically characterized by a superficial dermal proliferation of basaloid cells growing in narrow strands embedded in a desmoplastic stroma associated with small keratinizi...

journal_title：Journal of cutaneous pathology

authors： Jedrych J,Leffell D,McNiff JM

更新日期：2012-03-01 00:00:00

abstract：:A case of pigmented hidrocystoma of eccrine secretory coil is presented. A 47-year-old woman had developed a bluish black small nodule in the anterior portion of the labium minor a few years before entry. Microscopically, the cyst was lined by eosinophilic columnar epithelium with abundant brownish granules. There was...

journal_title：Journal of cutaneous pathology

authors： Kamishima T,Igarashi S,Takeuchi Y,Ito M,Fukuda T

更新日期：1999-03-01 00:00:00

abstract：:Antibodies reactive with S100 protein are useful markers in a diagnostic immunohistochemistry laboratory dealing with cutaneous tumors. However, S100 protein is not a single protein but instead a group of S100 proteins with diverse functions. S100 proteins constitute a family of acidic calcium-binding proteins that ar...

journal_title：Journal of cutaneous pathology

authors： McNutt NS

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Mucocutaneous depositions of various metals such as silver, lead, gold, arsenic, mercury, iron, and bismuth have been previously published. Heavy metal deposition typically occurs in the setting of either prolonged topical application to intact skin, topical application to eroded or ulcerated skin, as a resu...

journal_title：Journal of cutaneous pathology

authors： Greenberg JE,Lynn M,Kirsner RS,Elgart GW,Hanly AJ

更新日期：2002-11-01 00:00:00

abstract：:Cutaneous mastocytosis is a disease characterized by the infiltration and proliferation of mast cells in the skin. In children, the most common form of presentation is urticaria pigmentosa, while the diffuse cutaneous bullous mastocytosis is one of the rarest subtypes seen. The aim of this paper is to present a case o...

journal_title：Journal of cutaneous pathology

authors： Slavescu KC,Chiorean R,Danescu S,Bota M,Rogojan L,Baican A

更新日期：2016-03-01 00:00:00

abstract：:Adult-onset Still disease (AOSD) is a rare autoinflammatory syndrome characterized by recurring fevers, arthralgia, and consistent laboratory abnormalities that include leukocytosis and hyperferritinemia. Skin findings accompany the disease in nearly 90% of the cases. Early reports described evanescent, pruritic, salm...

journal_title：Journal of cutaneous pathology

authors： Santa E,McFalls JM,Sahu J,Lee JB

更新日期：2017-06-01 00:00:00

abstract：:In seven patients suffering from lichen planus (LP) light- and electron-microscopic 3H-thymidine (3HT) labeling studies were performed and the following results were obtained. 1. Using the light-microscope, a large number of 3HT labeled cells can be observed in the dermal infiltrate of LP. Most of the labeled nuclei b...

journal_title：Journal of cutaneous pathology

authors： Ebner H,Jurecka W

更新日期：1977-09-01 00:00:00