Epidermotropic metastases from breast carcinoma showing different clinical and histopathological features on the trunk and on the scalp in a single patient.

abstract：:The rare presentation of choriocarcinoma as a cutaneous metastasis in a 23-year-old male is reported. Histological and immunohistochemical analysis of the biopsy material demonstrated two distinct cell populations, syncytiotrophoblasts and cytotrophoblasts, with syncytiotrophoblasts strongly positive for human chorion...

journal_title：Journal of cutaneous pathology

authors： Chhieng DC,Jennings TA,Slominski A,Mihm MC Jr

更新日期：1995-08-01 00:00:00

abstract：:This report deals with seven examples of an epithelial cyst for which we have found no proper designation in the classification of epithelial skin cysts. Clinically, the lesion is often hyperpigmented, located in mid-dermis and shows epidermoid keratinization. The cyst contains laminated keratin, many pigmented hair s...

journal_title：Journal of cutaneous pathology

authors： Mehregan AH,Medenica M

更新日期：1982-12-01 00:00:00

abstract：:A survey of conditions with mucinous deposits is given. The most important factors for their diagnosis are to consider these disorders and to stain the slides for proteoglycans or glycosaminoglycans; the most common routine techniques are the Giemsa and the Alcian-blue stain. More sophisticated methods allow different...

journal_title：Journal of cutaneous pathology

authors： Steigleder GK,Küchmeister B

更新日期：1985-06-01 00:00:00

abstract：:This study compared the fine structure of macromelanosomes with that of giant melanosome complexes formed through melanosomal autophagocytosis in nevocytes and melanocytes of nevocellular nevi, lentigo simplex and malignant melanoma. While macromelanosomes were found only on rare occasions in these pigmentary disorder...

journal_title：Journal of cutaneous pathology

authors： Horikoshi T,Jimbow K,Sugiyama S

更新日期：1982-10-01 00:00:00

abstract：BACKGROUND:Cicatricial forms of alopecia, including lichen planopilaris (LPP) and discoid lupus erythematosus (DLE), may present with overlapping clinical features. In such cases, histopathological examination may provide key information for resolving the differential diagnosis. Optimally, microscopical analysis for al...

journal_title：Journal of cutaneous pathology

authors： Nguyen JV,Hudacek K,Whitten JA,Rubin AI,Seykora JT

更新日期：2011-05-01 00:00:00

abstract：:Herpetic syringitis has been described as a rare manifestation of herpes virus infection in patients with an immunodeficiency, usually secondary to human immunodeficiency virus (HIV) infection. Eccrine squamous syringometaplasia (ESS) is an infrequent alteration of the eccrine duct epithelium reported in association w...

journal_title：Journal of cutaneous pathology

authors： Muñoz E,Valks R,Fernández-Herrera J,Fraga J

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Tumor-infiltrating lymphocytes (TILs) are considered to play an important role in the antitumoral immune response. The presence and percentage of CD8-positive tumor-infiltrating T cells have been shown to correlate with differentiation and prognosis in various neoplasms. The aim of this study was to determin...

journal_title：Journal of cutaneous pathology

authors： Kamarashev J,Schaerer L,Burg G,Schmid MH,Müller B,Kempf W

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Pyoderma gangrenosum (PG) is a non-infectious, autoimmune, chronic ulcer of the skin, often co-existing with inflammatory bowel disease (IBD). Matrix metalloproteinases (MMPs) have been implicated as mediators of tissue destruction in chronic cutaneous and intestinal wounds. METHODS:Twenty-four skin biopsie...

journal_title：Journal of cutaneous pathology

authors： Bister V,Mäkitalo L,Jeskanen L,Saarialho-Kere U

更新日期：2007-12-01 00:00:00

abstract：:CD44 is a widely distributed cell surface protein thought to be involved in multiple steps of normal immune cell function, including T-cell activation, and in cellular adhesion where it mediates cell attachment to hyaluronate. In normal skin, CD44 is found by immunohistochemical means to be primarily in eccrine coil c...

journal_title：Journal of cutaneous pathology

authors： Sawaya ME,Bakshandeh H,Hordinsky MK,Penneys NS

更新日期：1994-06-01 00:00:00

abstract：:In lymph nodes, classical Hodgkin lymphoma can typically be distinguished from non-Hodgkin lymphoma (NHL) by the presence of Hodgkin and Reed-Sternberg cells that co-express CD30 and CD15. However, anaplastic large cell lymphoma (ALCL) and diffuse large B-cell lymphoma (DLBCL) can show identical features, and some cas...

journal_title：Journal of cutaneous pathology

authors： Cho RJ,McCalmont TH,Ai WZ,Fox LP,Treseler P,Pincus LB

更新日期：2012-06-01 00:00:00

abstract：:The bcl-2 proto-oncogene encodes a protein that protects cells from programmed cell death (apoptosis). High levels of this protein confer a growth advantage to neoplastic cells even in the absence of a high mitotic rate. This gene is involved in the interchromosomal 14;18 translocation, an abnormality present in more ...

journal_title：Journal of cutaneous pathology

authors： Cerroni L,Kerl H

更新日期：1994-10-01 00:00:00

abstract：:The histopathologic findings in 331 cases of necrobiosis lipoidica diabeticorum seen during a 50-year period were reviewed. Three cases showing cholesterol cleft formation were found. All 3 cases were associated with severe diabetes mellitus. The differential diagnosis of importance is necrobiotic xanthogranuloma. Com...

journal_title：Journal of cutaneous pathology

authors： Gibson LE,Reizner GT,Winkelmann RK

更新日期：1988-02-01 00:00:00

abstract：:During the past decade, a group of cells located in the dermis and possessing a dendritic morphology have emerged from obscurity and become recognized as important members of the "dermal immune system". This group of cells is characterized by a considerable degree of immunophenotypic and functional heterogeneity. In t...

journal_title：Journal of cutaneous pathology

authors： Nestle FO,Nickoloff BJ

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Acquired lymphedema of the genitalia is a rare childhood presentation and is more common in elderly individuals secondary to pelvic/abdomenal malignancy or its therapy or worldwide due to filariasis. OBJECTIVE:Herein, we report a case of a healthy 11-year-old boy who presented with a 1-year history of chron...

journal_title：Journal of cutaneous pathology

authors： Murphy MJ,Kogan B,Carlson JA

更新日期：2001-09-01 00:00:00

abstract：BACKGROUND:Cutaneous Rosai-Dorfman disease (CRDD) shares the histopathological features of abundant plasma cells and stromal fibrosis with IgG4-related sclerosing disease. The possible role of IgG4+ plasma cells in CRDD was investigated. METHODS:Twelve cases of CRDD were reviewed, and their lesions were immunostained ...

journal_title：Journal of cutaneous pathology

authors： Kuo TT,Chen TC,Lee LY,Lu PH

更新日期：2009-10-01 00:00:00

abstract：:We report the case of a 51-year-old man with an asymptomatic indurated plaque on the chest wall that was surgically excised and submitted for histopathological examination. Microscopically, the dermis was occupied by a neoplastic process with spindle-shaped cells arranged in longitudinal fascicles with cytologic atypi...

journal_title：Journal of cutaneous pathology

authors： Berzal-Cantalejo F,Sabater-Marco V,Pérez-Vallés A,Martorell-Cebollada M

更新日期：2006-09-01 00:00:00

abstract：:Mycosis fungoides in palmoplantar localization (MFPP) is a rare variant of MF that is confined to the hands and feet. Patients commonly receive treatment over many years for suspected palmoplantar dermatitis before the diagnosis is made. Most MFPP patients remain at patch or plaque stage, and often respond to treatmen...

journal_title：Journal of cutaneous pathology

authors： Pham AK,Carter JB,Ratcliffe NR,Fuld AD,Lansigan F,Burnside NJ,Guill MA 3rd,Zug KA,Jarvis LA,LeBlanc RE

更新日期：2018-06-01 00:00:00

abstract：:The increased susceptibility of the skin of chronically immunosuppressed individuals to viral infections and sunlight-induced malignancies suggests specific drug-induced, dysfunction of local immune mechanisms within the sun-exposed skin of these individuals. To help understand the effect of immunosuppressive therapy ...

journal_title：Journal of cutaneous pathology

authors： Kelly G,Scheibner A,Murray E,Sheil R,Tiller D,Horvath J

更新日期：1987-08-01 00:00:00

abstract：:We report a case of disseminated Trichosporon asahii in a patient on systemic antifungal therapy who presented with multiple cutaneous nodules suggestive of fungal infection. Histologic features resembled neutrophilic eccrine hidradenitis but staining with periodic acid-Schiff and Gomori methenamine silver confirmed t...

journal_title：Journal of cutaneous pathology

authors： Galligan ER,Fix L,Husain S,Zachariah P,Yamashiro DJ,Lauren CT

更新日期：2019-02-01 00:00:00

abstract：:As many as 40% of all primary cutaneous melanomas can have histologic remnants of nevomelanocytic nevi adjacent to the tumor. There is increasing evidence that dysplastic nevi are at least a clinical marker for melanoma risk. Spitz nevi are not known for such an association, but are noteworthy because of their histolo...

journal_title：Journal of cutaneous pathology

authors： Winokur TS,Palazzo JP,Johnson WC,Duray PH

更新日期：1990-12-01 00:00:00

abstract：:Epidermal Langerhans cells (LC) from skin of clinically normal appearance in psoriatics were studied electron microscopically and compared with LC from the skin of healthy volunteers and from those with other dermatoses. Results show that LC from psoriatics display partly distinct cytoplasmic alterations. Moreover, ab...

journal_title：Journal of cutaneous pathology

authors： Klug H,Sönnichsen N

更新日期：1988-12-01 00:00:00

abstract：:Bullous pemphigoid (BP) antigen and alpha 6 integrin are hemidesmosome-associated glycoproteins of basal keratinocytes. In this work, the immunoreactivity of antibodies to BP and to alpha 6 in salt- or dispase-split human skin, and in 46 biopsy specimens of various genetic and autoimmune bullous dermatoses taken from ...

journal_title：Journal of cutaneous pathology

authors： Kanitakis J,Zambruno G,Vassileva S,Giannetti A,Thivolet J

更新日期：1992-10-01 00:00:00

abstract：:Biologic therapies targeting tumor necrosis factor (TNF)-alpha have become a mainstay in the management of a number of autoimmune diseases. We report a series of adverse skin eruptions in six patients (four females, two males, age: 21-58 years, mean: 39) receiving 4 months to 10 years (mean 3.1 years) of anti-TNF-alph...

journal_title：Journal of cutaneous pathology

authors： Hawryluk EB,Linskey KR,Duncan LM,Nazarian RM

更新日期：2012-05-01 00:00:00

abstract：:Goltz syndrome (focal dermal hypoplasia) is an X-linked dominant disorder that is classically associated with yellowish papules representing fat herniation (superficial adipocytes). We report a series of three cases, with clinicopathologic correlation of biopsies from Blaschkoid streaks. A range of histopathologic fea...

journal_title：Journal of cutaneous pathology

authors： Ko CJ,Antaya RJ,Zubek A,Craiglow B,Damsky W,Galan A,McNiff JM

更新日期：2016-05-01 00:00:00

abstract：:A tumor of 60 years' duration overlying the sternum of an 87-year-old woman is described. Histologically, the tumor was composed of lobules and cords of epithelial cells with finely granular, eosinophilic cytoplasm. The epithelial nests were floating in large pools of mucinous stroma, separated by thin fibrovascular s...

journal_title：Journal of cutaneous pathology

authors： Sakamoto F,Ito M,Matumura G,Sato Y,Kimura S

更新日期：1991-04-01 00:00:00

abstract：:The skin biopsy specimens from six patients with primary mixed IgM-IgG cryoglobulinemia were examined by immunofluorescence, light and electron microscopy. The biopsy taken from the involved skin of one patient with leg ulcers revealed small blood vessel occlusions by cryoglobulin aggregates. Since a similar finding w...

journal_title：Journal of cutaneous pathology

authors： Berliner S,Weinberger A,Ben-Bassat M,Idesess C,Hazaz B,David M,Pinkhas J

更新日期：1982-04-01 00:00:00

abstract：:A 48 year-old white male with basal cell nevus syndrome presented with a metastatic basal cell carcinoma with neuroendocrine features. The tumor manifested aggressive behavior, having deep local invasion and metastases to para-aortic lymph nodes and bone. Neuroendocrine differentiation has rarely been associated with ...

journal_title：Journal of cutaneous pathology

authors： Tawfik O,Casparian JM,Garrigues N,Smith S,Kestenbaum T,Chamberlin F,Khan QS

更新日期：1999-07-01 00:00:00

abstract：INTRODUCTION:The atypical fibroxanthoma (AFX) is considered by most authorities to represent a superficial or minimally invasive variant of malignant fibrous histiocytoma that most often presents as a solitary nodule on the sun-exposed skin of the elderly. Among the rarest variants is the clear cell AFX, a lesion which...

journal_title：Journal of cutaneous pathology

authors： Crowson AN,Carlson-Sweet K,Macinnis C,Taylor JR,Battaglia T,LaMar WL,Minor D,Sutter S,Hill T

更新日期：2002-07-01 00:00:00

abstract：:Atypical cellular blue nevus (ACBN) has clinicopathologic features intermediate between typical cellular blue nevus (CBN) and the rare malignant blue nevus (MBN)/malignant melanoma (MM) arising in a CBN. Herein we report 9 cases of ACBN. The patients were caucasian (6 females and 3 males) with a mean and median age of...

journal_title：Journal of cutaneous pathology

authors： Tran TA,Carlson JA,Basaca PC,Mihm MC

更新日期：1998-05-01 00:00:00

abstract：:We have quantified perivascular mast cells in cases of urticaria pigmentosa, urticaria, and dermal hypersensitivity reactions. To facilitate reproducibility, the mast cells were counted for a precisely defined vessel unit. These vessel units were divided arbitrarily into those < or = 55 microns and > 55 microns in lar...

journal_title：Journal of cutaneous pathology

authors： Sweet WL,Smoller BR

更新日期：1996-06-01 00:00:00