Churg-Strauss syndrome with coexistence of eosinophilic vasculitis, granulomatous phlebitis and granulomatous dermatitis in bullous pemphigoid-like blisters.

abstract：:The internal organization of plasma membranes was studied in seven subjects with pemphigus vulgaris and in one subject with familial pemphigus using the freeze-fracture technique. The results obtained seem to suggest that the acantholytic process is produced in a similar fashion whatever the pathogenic agent and that ...

journal_title：Journal of cutaneous pathology

authors： Caputo R,Innocenti M,Gasparini G

更新日期：1980-04-01 00:00:00

abstract：:Adenomyoepithelioma is a rare, microscopically distinctive tumor of the skin. This article explores an example that presented in the inguinal area in a 29-year-old woman, mimicking adenopathy. Histopathologically, the tumor included two different areas: a cystic area consisting of tubules and glands in hyalinized stro...

journal_title：Journal of cutaneous pathology

authors： Sabater Marco V

更新日期：2012-07-01 00:00:00

abstract：:With the exception of skin cancer, prostatic adenocarcinoma represents the most common cancer among men in the United States and the second most common cause of cancer mortality. Mortality is often associated with metastatic disease, which in the case of prostatic adenocarcinoma typically involves bones and only rarel...

journal_title：Journal of cutaneous pathology

authors： Rattanasirivilai A,Kurban A,Lenzy YM,Yaar R

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Rhabdomyosarcoma is a malignant mesenchymal tumor with skeletal muscle differentiation. Primary cutaneous rhabdomyosarcoma is rare. We report a series of 11 cases of primary cutaneous rhabdomyosarcoma. METHODS:Cases diagnosed as rhabdomyosarcoma arising in the dermis/subcutis with no identified primary tumo...

journal_title：Journal of cutaneous pathology

authors： Marburger TB,Gardner JM,Prieto VG,Billings SD

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:The cell origin of dermatofibroma (DF) has not been clarified satisfactorily. This study was undertaken to assess the distribution of fibroblasts and the relationship between fibroblasts and other constituent cells in DF by 47-kDa heat-shock protein (HSP47), a cell marker for skin fibroblast. METHODS:Immuno...

journal_title：Journal of cutaneous pathology

authors： Kuroda K,Tajima S

更新日期：2008-01-01 00:00:00

abstract：BACKGROUND:Chronic urticaria is a condition with many inciting factors and often presents a therapeutic challenge to clinicians. In addition to a central role for mast cells, an immune dysregulated state related to cytokine/chemokine alterations is increasingly being recognized. METHODS:Biopsies of chronic urticaria (...

journal_title：Journal of cutaneous pathology

authors： Moy AP,Murali M,Nazarian RM

更新日期：2016-04-01 00:00:00

abstract：:Langerhans cell histocytosis (LCH) and Erdheim-Chester disease are two rare histiocytic disorders. Their occurrence in the same patient is more infrequent, but has been described. We report a case of a 38-year-old woman who presented with a diagnosis of single system cutaneous LCH. Subsequently, she developed multiple...

journal_title：Journal of cutaneous pathology

authors： Johnson WT,Patel P,Hernandez A,Grandinetti LM,Huen AC,Marks S,Ho J,Monaco SE,Jaffe R,Picarsic J

更新日期：2016-03-01 00:00:00

abstract：:The so-called perivascular epithelioid cell neoplasm (PEComa) family includes angiomyolipoma, clear cell 'sugar' tumor (CCST), lymphangioleiomyomatosis, and clear cell myomelanocytic tumor (CCMMT). These rare tumors are characterized by the co-expression of melanocytic and muscle markers. They have been recognized in ...

journal_title：Journal of cutaneous pathology

authors： de Saint Aubain Somerhausen N,Gomez Galdon M,Bouffioux B,Courtin C,Theunis A,Vogeleer MN,Myant N

更新日期：2005-07-01 00:00:00

abstract：:We report on two patients with chronic myeloid leukemia (CML) who presented blastic transformation involving the skin, with leukemic infiltrates showing unusual morphologic and immunohistologic characteristics. Both patients were elderly men with a 36-month and a 40-month history of CML, respectively. They presented w...

journal_title：Journal of cutaneous pathology

authors： Kaddu S,Beham-Schmid C,Zenahlik P,Kerl H,Cerroni L

更新日期：1999-11-01 00:00:00

abstract：:A 27-year-old woman developed many nodular lesions, ranging in diameter from 3 mm to 15 mm and clinically indistinguishable from dermatofibromas. Light microscopic examination showed large amounts of mucin, fibroblasts and histiocytes throughout the dermis. Electron microscopic study revealed wide electron lucent area...

journal_title：Journal of cutaneous pathology

authors： Zina AM,Bundino S

更新日期：1980-12-01 00:00:00

abstract：:Atypical cellular blue nevus (ACBN) has clinicopathologic features intermediate between typical cellular blue nevus (CBN) and the rare malignant blue nevus (MBN)/malignant melanoma (MM) arising in a CBN. Herein we report 9 cases of ACBN. The patients were caucasian (6 females and 3 males) with a mean and median age of...

journal_title：Journal of cutaneous pathology

authors： Tran TA,Carlson JA,Basaca PC,Mihm MC

更新日期：1998-05-01 00:00:00

abstract：:"Adenoma sebaceum of Pringle" (ASP) is a misnomer. The tumor is not an adenoma and is not derived from sebaceous glands. The lesion is characterized by dermal fibrosis and associated vascular proliferation and dilatation. Changes in contiguous sebaceous glands and other adnexal structures are merely secondary. Thus, "...

journal_title：Journal of cutaneous pathology

authors： Sanchez NP,Wick MR,Perry HO

更新日期：1981-12-01 00:00:00

abstract：:We describe a patient with thrombocytopenia-absent radius (TAR) syndrome, multisystemic Langerhans cell histiocytosis and multiple reticulohistiocytomas. A mutational study by massive sequencing identified the Val600Glu (V600E) BRAF mutation in the Langerhans cell histiocytosis lesions, but no molecular alterations we...

journal_title：Journal of cutaneous pathology

authors： Hipólito LN,Mendoza-Cembranos MD,Villaescusa MT,Jo-Velasco M,Requena L,Alegría-Landa V

更新日期：2019-08-01 00:00:00

abstract：:We present the case of a 77-year-old male undergoing treatment for mycosis fungoides (MF) who presented for removal of an acrochordon on his mid back. Histopathologic examination of the acrochordon revealed a dense, band-like lymphocytic inflammatory infiltrate in the dermis with epidermotropism of single lymphocytes ...

journal_title：Journal of cutaneous pathology

authors： McClain CM,Cole MB,Robbins JB,Kantrow SM

更新日期：2012-12-01 00:00:00

abstract：:Verrucous hemangioma represents a rare congenital vascular proliferation that may be mistaken for angiokeratoma. Histopathological examination of a deep biopsy is necessary to confirm the diagnosis of verrucous hemangioma based on its involvement of the deep dermis and subcutaneous tissue. We present two cases of verr...

journal_title：Journal of cutaneous pathology

authors： Clairwood MQ,Bruckner AL,Dadras SS

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:Merkel cell carcinoma (MCC) is an aggressive neoplasm, which is often associated with Merkel cell polyomavirus (MCPyV). Programmed death-1 (PD-1) and its ligand PD-L1 are key players of the tumor microenvironment (TME). METHODS:Fourteen paraffin-embedded tissue samples of MCC were stratified by their MCPyV ...

journal_title：Journal of cutaneous pathology

authors： Mitteldorf C,Berisha A,Tronnier M,Pfaltz MC,Kempf W

更新日期：2017-09-01 00:00:00

abstract：:A 34-year-old man with acquired immunodeficiency syndrome presented with multiple skin lesions clinically suggestive of molluscum contagiosum. Three skin biopsy specimens were obtained which showed dermal abscesses containing multiple gram-positive cocci admixed with granular necrotic dermal material. In 2, there were...

journal_title：Journal of cutaneous pathology

authors： Boudreau S,Hines HC,Hood AF

更新日期：1988-02-01 00:00:00

abstract：:Cutaneous syncytial myoepithelioma is a recently described rare tumor of the dermis. It is derived and composed purely of myoepithelial cells and shows a characteristic syncytial growth pattern of neoplastic cells with little intervening stroma and no recognizable ductal structures. It represents a diagnostic challeng...

journal_title：Journal of cutaneous pathology

authors： Alomari AK,Brown N,Andea AA,Betz BL,Patel RM

更新日期：2017-10-01 00:00:00

abstract：:LL-37 is a naturally occurring 37-amino-acid peptide that is part of the innate immune system in human skin. Preclinical studies have showed that intra-tumoral injections of LL-37 stimulate the innate immune system by activation of plasmacytoid dendritic cells, which mediate tumor destruction. LL-37 intra-tumoral inje...

journal_title：Journal of cutaneous pathology

authors： Dolkar T,Trinidad CM,Nelson KC,Amaria RN,Nagarajan P,Torres-Cabala CA,Ivan D,Prieto VG,Tetzlaff MT,Curry JL,Aung PP

更新日期：2018-07-01 00:00:00

abstract：:In the past decades, the incidence of melanoma has been reported to rise in epidemic proportions. The chief reason for that pseudo-epidemic is improved criteria for diagnosis that allow melanomas to be recognized far more accurately and at earlier stages. The rising number of melanomas diagnosed has resulted in increa...

journal_title：Journal of cutaneous pathology

authors： Weyers W

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Nestin is one of the intermediate filaments that are expressed in proliferating neural progenitor cells during development of the central nervous system (CNS) and peripheral nervous system. Postnatal re-expression of the protein occurs mainly under pathological conditions, including injury and neoplasia. In ...

journal_title：Journal of cutaneous pathology

authors： Brychtova S,Fiuraskova M,Hlobilková A,Brychta T,Hirnak J

更新日期：2007-05-01 00:00:00

abstract：:Exposure to silver-containing compounds can result in reversible discoloration of the skin, presenting as an irregular brown or black macule, which can have a clinical appearance similar to melanoma. Both the clinical scenario and the histopathology are unique. Silver nitrate darkens with exposure to light, and the ar...

journal_title：Journal of cutaneous pathology

authors： Ondrasik RM,Jordan P,Sriharan A

更新日期：2020-12-01 00:00:00

abstract：:The usual method for detecting spirochetes in tissue sections is the silver stain; however, they are often difficult to detect due to marked background staining commonly seen with this technique. In certain clinical settings, such as neurosyphilis, congenital syphilis, and immunosuppressive conditions including human ...

journal_title：Journal of cutaneous pathology

authors： Hoang MP,High WA,Molberg KH

更新日期：2004-10-01 00:00:00

abstract：:The histopathologic findings in 331 cases of necrobiosis lipoidica diabeticorum seen during a 50-year period were reviewed. Three cases showing cholesterol cleft formation were found. All 3 cases were associated with severe diabetes mellitus. The differential diagnosis of importance is necrobiotic xanthogranuloma. Com...

journal_title：Journal of cutaneous pathology

authors： Gibson LE,Reizner GT,Winkelmann RK

更新日期：1988-02-01 00:00:00

abstract：:In seven patients suffering from lichen planus (LP) light- and electron-microscopic 3H-thymidine (3HT) labeling studies were performed and the following results were obtained. 1. Using the light-microscope, a large number of 3HT labeled cells can be observed in the dermal infiltrate of LP. Most of the labeled nuclei b...

journal_title：Journal of cutaneous pathology

authors： Ebner H,Jurecka W

更新日期：1977-09-01 00:00:00

abstract：:Peristomal ulcer with cutaneous intestinal metaplasia, defined by scattered colonic crypts within variably intact epidermis, is an exceedingly rare pathologic diagnosis, which possesses the potential to progress to primary adenocarcinoma. Herein, we report the third case of cutaneous intestinal metaplasia in a peristo...

journal_title：Journal of cutaneous pathology

authors： Tinker DG,Roberts S,Hurley MY,Missall TA

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Psoriasis vulgaris is a common chronic inflammatory dermatosis. Disorders in keratinocyte proliferation, differentiation, inflammation and immune dysregulation are the major factors implicated in the pathogenesis of psoriasis vulgaris. METHODS:The study was performed in skin specimens of 25 patients with ps...

journal_title：Journal of cutaneous pathology

authors： Doger FK,Dikicioglu E,Ergin F,Unal E,Sendur N,Uslu M

更新日期：2007-03-01 00:00:00

abstract：:Endocrine mucin-producing sweat gland carcinoma is a cutaneous adnexal tumor that is rarely reported in the literature. We identified only 29 previously reported cases. All these cases share some clinical morphologic and immunohistochemical features. Among the immunohistochemical markers, cytokeratins 5/6, 8 and 18 (C...

journal_title：Journal of cutaneous pathology

authors： Fernandez-Flores A,Cassarino DS

更新日期：2015-08-01 00:00:00

abstract：:Recently, T-cell lymphoma localized to the subcutaneous tissue has been reported. We report the clinical, histologic, immunohistochemical, and molecular genetic findings in 6 patients who we believe had this peculiar T-cell lymphoma with its unique morphologic and clinical features. All patients presented with deep-se...

journal_title：Journal of cutaneous pathology

authors： Mehregan DA,Su WP,Kurtin PJ

更新日期：1994-04-01 00:00:00

abstract：:Melanoma is known to show considerable variation in its histopathological presentation. In exceptional cases, heterologous or divergent differentiation (metaplastic melanoma) can be observed. We report a case of a 69-year-old man who was diagnosed with nodular melanoma on the right upper leg. One year later, the patie...

journal_title：Journal of cutaneous pathology

authors： Kilsdonk MJ,Romeijn TR,Kelder W,van Kempen LC,Diercks GF

更新日期：2020-12-01 00:00:00