Ultrastructural study of nuclear inclusions in spindle and epithelioid cell nevus cells.

abstract：:The three-dimensional morphology of six dermatofibromas was studied by scanning electron microscopy. Hypertrophic epidermal ridges covered with large keratinized cells overlay each dermal lesion. Small collagenous fibers in the tumors contrasted with the bundles of much larger collagenous fibers in the normal dermis p...

journal_title：Journal of cutaneous pathology

authors： Wilborn WH,Montes LF

更新日期：1979-08-01 00:00:00

abstract：:A 31 year old Indian woman presented with bilateral axillary masses that became noticeable with the onset of puberty. The masses exhibited similar consistency to the adjacent normal breast tissue but lacked an associated nipple complex. The clinical impression was lipoma; however, mammography, ultrasonography and skin...

journal_title：Journal of cutaneous pathology

authors： Ghosn SH,Khatri KA,Bhawan J

更新日期：2007-12-01 00:00:00

abstract：:Recent advances in the understanding of the metastatic phenomenon in cancer have led to the description of a metastatic niche. This concept describes a site prepared for the tumor cells in areas frequently associated with metastasis for the individual tumor studied. This niche is a "soil" that allows for the tumor cel...

journal_title：Journal of cutaneous pathology

authors： Mihm MC Jr,Nelson JS

更新日期：2010-04-01 00:00:00

abstract：:Superficial acral fibromyxoma (SAFM) is an uncommon mesenchymal soft tissue tumor with a predilection for the acral extremites and nail bed involvement. SAFM is diagnosed with clinicopathological and immunohistochemical examination. Awareness of this rare tumor is important because of amounts of benign and malignant n...

journal_title：Journal of cutaneous pathology

authors： Kara Polat A,Gore Karaali M,Turgut Erdemir AV,Koku Aksu AE,Leblebici C,Gurel MS

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Trichilemmal (pilar) cysts are common skin lesions that usually occur on the scalp of elderly women. They differentiate towards the follicular outer root sheath epithelium and show trichilemmal keratinization. Proliferating trichilemmal tumor (PTT) shows features of typical pilar cyst, but additionally shows...

journal_title：Journal of cutaneous pathology

authors： Folpe AL,Reisenauer AK,Mentzel T,Rütten A,Solomon AR

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:The GATA family of transcription factors is an essential regulator of cellular proliferation and differentiation. In the skin, GATA-3 is critical for epidermal stratification and maintenance of barrier function. A role for GATA-3 in the development of human cutaneous squamous cell carcinoma (SCC) is not know...

journal_title：Journal of cutaneous pathology

authors： Solus JF,Hassan K,Lee SJ,Hsi AC,Rosman IS,Dehmeri S,Schaffer A

更新日期：2016-04-01 00:00:00

abstract：:A 12-year-old male presented with an 8-year history of five firm cream colored papules on the right vertex of the scalp. A biopsy showed a dense infiltrate of monomorphous mast cells involving the dermis and extending into the subcutis. A relatively well-circumscribed cluster of larger cells showed pleomorphic nuclei ...

journal_title：Journal of cutaneous pathology

authors： Lachapelle J,Moroz B,Nguyen VH

更新日期：2012-08-01 00:00:00

abstract：:We have quantified perivascular mast cells in cases of urticaria pigmentosa, urticaria, and dermal hypersensitivity reactions. To facilitate reproducibility, the mast cells were counted for a precisely defined vessel unit. These vessel units were divided arbitrarily into those < or = 55 microns and > 55 microns in lar...

journal_title：Journal of cutaneous pathology

authors： Sweet WL,Smoller BR

更新日期：1996-06-01 00:00:00

abstract：:The bcl-2 proto-oncogene encodes a protein that protects cells from programmed cell death (apoptosis). High levels of this protein confer a growth advantage to neoplastic cells even in the absence of a high mitotic rate. This gene is involved in the interchromosomal 14;18 translocation, an abnormality present in more ...

journal_title：Journal of cutaneous pathology

authors： Cerroni L,Kerl H

更新日期：1994-10-01 00:00:00

abstract：:The expression and localization of connexin 43 (Cx43) were investigated in normal human epidermis, pilosebaceous apparatus, basal cell carcinoma, and squamous cell carcinoma by immunofluorescence as well as by immunoelectron microscopy. In the normal epidermis the immunofluorescence was weak in the basal layer, increa...

journal_title：Journal of cutaneous pathology

authors： Tada J,Hashimoto K

更新日期：1997-11-01 00:00:00

abstract：:Folliculo-sebaceous hamartomas comprise a series of entities whose boundaries are imprecise. We present the clinical case of a folliculo-sebaceous cystic hamartoma of genital localization where the diagnosis was established based on the epithelial proliferation, but mostly, on the characteristic stroma. Because this l...

journal_title：Journal of cutaneous pathology

authors： Alegría-Landa V,Jo-Velasco M,Prieto-Torres L,Requena L

更新日期：2017-05-01 00:00:00

abstract：:After intradermal testing with goldsodiumthiomalate (GSTM), 5 out of 8 patients developed skin papules at the test sites, which persisted up to 20 months. The lesions were surgically excised. Histology revealed pseudolymphoma of B and T cell type containing follicular structures and occasional small granulomas. The am...

journal_title：Journal of cutaneous pathology

authors： Kalimo K,Räsänen L,Aho H,Mäki J,Mustikkamki UP,Rantala I

更新日期：1996-08-01 00:00:00

abstract：:Steatocystoma multiplex is characterized by the development of numerous steatocystomas. The condition has occasionally been related to congenital bilateral preauricular sinuses. Herein, we present the third case of such an association, a 34-year-old male who was born with bilateral preauricular sinuses that were surgi...

journal_title：Journal of cutaneous pathology

authors： Fernandez-Flores A,Cuesta CC,García CS,del Río JS

更新日期：2014-08-01 00:00:00

abstract：:Two cases of juvenile elastoma (nevus elasticus in disseminated tumors) were histologically and ultrastructurally investigated. The predominant components of this disseminated dysembryoplasia are abnormal elastic fibers. Both cases showed numerous large elastic fibers with an abundant background matrix. The elastic mi...

journal_title：Journal of cutaneous pathology

authors： Ledoux-Corbusier M,Achten G,De Dobbeleer G

更新日期：1981-06-01 00:00:00

abstract：:A case of pigmented hidrocystoma of eccrine secretory coil is presented. A 47-year-old woman had developed a bluish black small nodule in the anterior portion of the labium minor a few years before entry. Microscopically, the cyst was lined by eosinophilic columnar epithelium with abundant brownish granules. There was...

journal_title：Journal of cutaneous pathology

authors： Kamishima T,Igarashi S,Takeuchi Y,Ito M,Fukuda T

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:Src-family tyrosine kinases (SFKs) are important regulators of keratinocyte growth and differentiation. In a broad range of cell types, persistent activation of SFKs correlates with increased cell proliferation. In this study, we determined if SFK activity is increased in cutaneous neoplasia and psoriasis, c...

journal_title：Journal of cutaneous pathology

authors： Ayli EE,Li W,Brown TT,Witkiewicz A,Elenitsas R,Seykora JT

更新日期：2008-03-01 00:00:00

abstract：:Three selected cases of transient acantholytic dermatosis were studied because of their definitive correlation with sweating due to fever and/ or bed-ridden situations. Biopsy specimens were serially sectioned and acantholysis was found in the acrosyringium or traced to connect to the acrosyringium in all biopsy speci...

journal_title：Journal of cutaneous pathology

authors： Hashimoto K,Moiin A,Chang MW,Tada J

更新日期：1996-04-01 00:00:00

abstract：:A case of squamous cell carcinoma (SCC) with regional lymph node metastasis in a 69-year-old Japanese man is reported. The tumor was characterized by the proliferation of peripheral basaloid, inner squamoid, and glycogen-rich cells, the presence of trichilemmal keratinization, and the presence of ladder-like, membrane...

journal_title：Journal of cutaneous pathology

authors： Yamamoto O,Asahi M,Horie A,Fujimoto S,Nakayama K

更新日期：1991-08-01 00:00:00

abstract：:Serum amyloid P component (SAP) is present not only in all types of cutaneous amyloidosis, but also in the normal dermal elastic fibers as well as abnormal elastic fibers, such as elastotic degeneration of elastic fibers in actinic keratosis. It was previously postulated that the colloid substance in colloid milium is...

journal_title：Journal of cutaneous pathology

authors： Hashimoto K,Black M

更新日期：1985-04-01 00:00:00

abstract：BACKGROUND:Bullous pemphigoid (BP) is the most common type of subepidermal bullous disease. Direct immunofluorescence (DIF) is the gold standard for diagnosis, but it requires a fresh tissue specimen. This study was conducted to evaluate the accuracy of using immunohistochemical (IHC) analysis for the detection of C4d ...

journal_title：Journal of cutaneous pathology

authors： Kamyab K,Abdolreza M,Ghanadan A,Mortazavi H,Nikoo A,Motavalli F,Nasimi M

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Hobnail hemangioma (targetoid hemosiderotic hemangioma) is a small benign vascular tumor of the superficial and mid-dermis. In contrast to its well-characterized histology, it has been unclear whether this tumor arises from blood vessel endothelial cells (BECs) or lymphatic vessel endothelial cells (LECs). ...

journal_title：Journal of cutaneous pathology

authors： Franke FE,Steger K,Marks A,Kutzner H,Mentzel T

更新日期：2004-05-01 00:00:00

abstract：:With the exception of skin cancer, prostatic adenocarcinoma represents the most common cancer among men in the United States and the second most common cause of cancer mortality. Mortality is often associated with metastatic disease, which in the case of prostatic adenocarcinoma typically involves bones and only rarel...

journal_title：Journal of cutaneous pathology

authors： Rattanasirivilai A,Kurban A,Lenzy YM,Yaar R

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:Scleroderma/morphea is characterized by expansion of the dermis with thickened collagen bundles and loss of CD34(+) dermal dendrocytes. Variable elastic fiber changes have been described, but to our knowledge, no systematic study of the elastic fiber pattern correlated with CD34 expression has been reported....

journal_title：Journal of cutaneous pathology

authors： Walters R,Pulitzer M,Kamino H

更新日期：2009-09-01 00:00:00

abstract：:We report 2 cases of congenital porokeratotic eccrine nevus in a 5-year-old girl and a 7-year-old boy. The clinical manifestations were those of nevus comedonicus palmaris. The histologic picture consisted of comedo-like dilatations and cornoid lamellae involving the eccrine ostia and ducts. One of the cases showed an...

journal_title：Journal of cutaneous pathology

authors： Moreno A,Pujol RM,Salvatella N,Alomar A,de Moragas JM

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:Histiocytic sarcoma is an exceedingly rare malignant neoplasm composed of cells with a monocyte/macrophage phenotype. In the current nosology of histiocytic neoplasms, histiocytic sarcoma is separate from indeterminate cell histiocytosis, a generally benign disorder characterized by proliferation of a CD1a+ ...

journal_title：Journal of cutaneous pathology

authors： Frater JL,Kling CW,Obadiah JM,Gardner LJ,Grosso LE,Resh B,Hurley MY

更新日期：2006-06-01 00:00:00

abstract：:An 11-year old Caucasian female with a remote history of urticaria pigmentosa presented with a neck mass. A biopsy demonstrated a large intradermal nodule composed of unusually large epithelioid mast cells, including a prominent subset with bi-lobed and multi-lobed nuclei. By immunohistochemistry, the cells expressed ...

journal_title：Journal of cutaneous pathology

authors： Tran DT,Jokinen CH,Argenyi ZB

更新日期：2009-11-01 00:00:00

abstract：:Calciphylaxis is a rare syndrome of vascular calcification with thrombosis that occurs most often in patients with end-stage renal disease, and it frequently portends a guarded prognosis. Rarely, nonuremic calciphylaxis (NUC) may occur; in this context, a strongly supportive histology is crucial in establishing the di...

journal_title：Journal of cutaneous pathology

authors： Nathoo RK,Harb JN,Auerbach J,Guo R,Vincek V,Motaparthi K

更新日期：2017-12-01 00:00:00

abstract：:The increased susceptibility of the skin of chronically immunosuppressed individuals to viral infections and sunlight-induced malignancies suggests specific drug-induced, dysfunction of local immune mechanisms within the sun-exposed skin of these individuals. To help understand the effect of immunosuppressive therapy ...

journal_title：Journal of cutaneous pathology

authors： Kelly G,Scheibner A,Murray E,Sheil R,Tiller D,Horvath J

更新日期：1987-08-01 00:00:00

abstract：:We report on two patients with chronic myeloid leukemia (CML) who presented blastic transformation involving the skin, with leukemic infiltrates showing unusual morphologic and immunohistologic characteristics. Both patients were elderly men with a 36-month and a 40-month history of CML, respectively. They presented w...

journal_title：Journal of cutaneous pathology

authors： Kaddu S,Beham-Schmid C,Zenahlik P,Kerl H,Cerroni L

更新日期：1999-11-01 00:00:00

abstract：:High-pressure paint guns deliver paint at approximately 3000 pounds per square inch. At this pressure, paint will penetrate the skin and spread quickly through fascial planes and tendon sheaths. The present case is that of a lesion from the finger of a 35-year-old white male in whom a history was initially unavailable...

journal_title：Journal of cutaneous pathology

authors： Stefanato CM,Turner MS,Bhawan J

更新日期：2005-02-01 00:00:00