Expression of CD44 isoforms and beta 1,6-branched oligosaccharides in human malignant melanoma is correlated with tumor progression but not with metastatic potential.

abstract：BACKGROUND:Recent genetic investigations support the idea that basal cell carcinoma (BCC) is trichoblastic carcinoma. However, it is generally thought that clear cell basal cell carcinoma is a result of degeneration rather than tricholemmal differentiation. METHODS:We report a case of BCC, with clear cell components, ...

journal_title：Journal of cutaneous pathology

authors： Misago N,Satoh T,Narisawa Y

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:Melanoma staging has depended on depth of invasion (Breslow thickness, BT), mitotic rate (MR) and ulceration. In anticipation of the AJCC's eighth edition, variability in pathologists' assessment of these factors and consequently in tumor staging was assessed. METHODS:One-hundred and fifteen cases of invasi...

journal_title：Journal of cutaneous pathology

authors： Taylor L,Hood K,Reisch L,Elmore J,Piepkorn M,Barnhill R,Knezevich S,Radick A,Elder D

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Even though only 33 cases of Erythromelanosis follicularis faciei et colli (EFFC) have been reported around the world, there have been no quantitative clinicopathological studies yet. The purpose of this study is to examine quantitatively clinical and histopathological evaluations of EFFC using image analysi...

journal_title：Journal of cutaneous pathology

authors： Kim MG,Hong SJ,Son SJ,Song HJ,Kim IH,Oh CH,Moon JS

更新日期：2001-03-01 00:00:00

abstract：:Folliculo-sebaceous hamartomas comprise a series of entities whose boundaries are imprecise. We present the clinical case of a folliculo-sebaceous cystic hamartoma of genital localization where the diagnosis was established based on the epithelial proliferation, but mostly, on the characteristic stroma. Because this l...

journal_title：Journal of cutaneous pathology

authors： Alegría-Landa V,Jo-Velasco M,Prieto-Torres L,Requena L

更新日期：2017-05-01 00:00:00

abstract：:Medallion-like dermal dendrocyte hamartoma is a rare congenital lesion that is more commonly seen in females. It often presents at birth on the neck or upper trunk as a well-circumscribed, atrophic patch with wrinkling of the overlying skin. Clinically, the differential diagnosis includes atrophoderma, anetoderma, and...

journal_title：Journal of cutaneous pathology

authors： Porubsky CF,Combs A,Buckley C,Goodman MB

更新日期：2019-04-01 00:00:00

abstract：:We present a challenging case of chronic, erosive, scarring dermatosis of the vulva with clinical features of long standing lichen sclerosus (LS), namely pallor and loss of vulval architecture, but with histopathology consistently showing features of an acantholytic process. The history and clinical features of this c...

journal_title：Journal of cutaneous pathology

authors： Haddadeen C,Theaker J,Rowen D,Lotery H

更新日期：2020-01-01 00:00:00

abstract：:Mycosis fungoides (MF) is a rare type of non-Hodgkin's lymphoma affecting the skin. Because MF develops slowly over several years and may have a variety of clinical presentations, including itchy patches, plaques or tumors that may be confused with common benign conditions such as eczema and psoriasis, the disease pre...

journal_title：Journal of cutaneous pathology

authors： Reddy K,Bhawan J

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:The migration of circulating monocytes into the dermis is considered to be essential for both the initiation and the progression of xanthoma. The contribution of vascular endothelial cells to the migration process is unclear. METHODS:Twenty cases of xanthelasma and six cases of tuberous xanthoma lesions wer...

journal_title：Journal of cutaneous pathology

authors： Matsumoto M,Kunimitsu S,Wada K,Ikeda M,Yokogawa M,Keyama A,Kodama H

更新日期：2007-10-01 00:00:00

abstract：:The low-fat and fat-free spindle cell lipomas (SCLs) are rare and often mistaken for other benign and malignant morphological mimics, because of the fact that the diagnosis relies on its non-lipogenic component analysis. Here, we report the clinicopathological features of two oral SCLs (low-fat and fat-free variants)....

journal_title：Journal of cutaneous pathology

authors： Rocha AFL,Miotto LN,Ferrisse TM,Silveira HA,Almeida LY,Bufalino A,Navarro CM,León JE

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Bullous pemphigoid (BP) is the most common type of subepidermal bullous disease. Direct immunofluorescence (DIF) is the gold standard for diagnosis, but it requires a fresh tissue specimen. This study was conducted to evaluate the accuracy of using immunohistochemical (IHC) analysis for the detection of C4d ...

journal_title：Journal of cutaneous pathology

authors： Kamyab K,Abdolreza M,Ghanadan A,Mortazavi H,Nikoo A,Motavalli F,Nasimi M

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:Langerhans' cells (CD1a positive, bone marrow-derived cells), are the antigen presenting cells of the skin. Our knowledge about the status of these cells in eczematous dermatitis is incomplete. AIM:This study tests the hypothesis that 'the development of eczematous dermatitis is associated with alterations ...

journal_title：Journal of cutaneous pathology

authors： Hussein MR

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Although skin carcinogenesis has been widely investigated, only limited information is available for epidermal tumors, while even less is known about other skin structures. Alterations in the β-catenin pathway have been reported in several epidermal tumors, while little is known about in adnexal tumors. This...

journal_title：Journal of cutaneous pathology

authors： Im M,Kim DH,Park JS,Chung H,Lee Y,Kim CD,Seo YJ,Lee JH

更新日期：2011-08-01 00:00:00

abstract：:Three selected cases of transient acantholytic dermatosis were studied because of their definitive correlation with sweating due to fever and/ or bed-ridden situations. Biopsy specimens were serially sectioned and acantholysis was found in the acrosyringium or traced to connect to the acrosyringium in all biopsy speci...

journal_title：Journal of cutaneous pathology

authors： Hashimoto K,Moiin A,Chang MW,Tada J

更新日期：1996-04-01 00:00:00

abstract：:Histologic, immunologic and electron microscopic studies were performed in a patient with transient acantholytic dermatosis which involved oral mucosa. Hitologic and electron microscopic findings were almost identical in both cutaneous and mucous membrane lesions, and these were similar to pemphigus vulgaris; suprabas...

journal_title：Journal of cutaneous pathology

authors： Kanzaki T,Hashimoto K

更新日期：1978-02-01 00:00:00

abstract：:We report a 2-year-old girl with developmental delay who, from the age of 1 year, developed perniotic lesions of the hands and feet initially diagnosed as chilblain lupus. Histological examination showed features of epidermal necrosis with intraepidermal bulla formation, interface dermatitis, lymphocytic vasculitis wi...

journal_title：Journal of cutaneous pathology

authors： Kolivras A,Aeby A,Crow YJ,Rice GI,Sass U,André J

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Pemphigoides gestationis (PG) is a blistering disorder of pregnancy caused by antibodies against basement membrane proteins. They are directed against the 180 kD bullous pemphigoid antigen (BPAg2), towards the epitopes within the NC 16A domain. There are many similarities between pemphigoid gestationis and b...

journal_title：Journal of cutaneous pathology

authors： Patton T,Plunkett RW,Beutner EH,Deng JS,Jukic DM

更新日期：2006-04-01 00:00:00

abstract：:We have quantified perivascular mast cells in cases of urticaria pigmentosa, urticaria, and dermal hypersensitivity reactions. To facilitate reproducibility, the mast cells were counted for a precisely defined vessel unit. These vessel units were divided arbitrarily into those < or = 55 microns and > 55 microns in lar...

journal_title：Journal of cutaneous pathology

authors： Sweet WL,Smoller BR

更新日期：1996-06-01 00:00:00

abstract：:Genital leiomyoma in men include those superficial leiomyomas arising in the scrotum and the areola. They are unusual neoplasms: few cases have been reported in the literature and they usually escape clinical diagnosis. Three cases of male genital leiomyomas are reported: two in the scrotum and one in the areola. They...

journal_title：Journal of cutaneous pathology

authors： Suárez-Peñaranda JM,Vieites B,Evgenyeva E,Vázquez-Veiga H,Forteza J

更新日期：2007-12-01 00:00:00

abstract：:A 35-year-old woman was examined because of a symptomless multiple annular eruption. The lesion consisted of rings of closely set, smooth, firm papules that were brown in color. Hemosiderotic histiocytoma was diagnosed by light and electron microscopy. Ultrastructurally, the lesion consisted of fibroblastic and histio...

journal_title：Journal of cutaneous pathology

authors： Saga K

更新日期：1981-06-01 00:00:00

abstract：BACKGROUND:De novo intraepidermal epithelioid melanocytic dysplasia (DNIEMD) is a newly characterized lesion that is associated with a personal and/or family history of malignant melanoma (MM) and/or dysplastic nevi (DN). However, the biological significance is still uncertain and the persons predisposed to this lesion...

journal_title：Journal of cutaneous pathology

authors： Jessup CJ,Cohen LM

更新日期：2010-08-01 00:00:00

abstract：:Free-living amebae are ubiquitous in our environment, but rarely cause cutaneous infection. Balamuthia mandrillaris has a predilection for infecting skin of the central face. Infection may be restricted to the skin or associated with life-threatening central nervous system (CNS) involvement. We report a case of a 91-y...

journal_title：Journal of cutaneous pathology

authors： Chang OH,Liu F,Knopp E,Muehlenbachs A,Cope JR,Ali I,Thompson R,George E

更新日期：2016-10-01 00:00:00

abstract：:A case study of sinus histiocytosis of Rosai-Dorfman (SH) clinically limited to the skin is presented with immunohistochemical study of the infiltrate, in both paraffin and cryostat sections. Factor XIIIa, a dendrocyte marker, was demonstrated in the cytoplasm of histiocytes. This feature had not been previously repor...

journal_title：Journal of cutaneous pathology

authors： Perrin C,Michiels JF,Lacour JP,Chagnon A,Fuzibet JG

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:Chronic amastigote-negative cutaneous leishmaniasis (CL) is a diagnostic challenge, as the parasite load may be low, or absent in biopsy tissue sections. METHODS:A series of consecutive biopsy specimens, taken from 130 patients with a diagnosis of granulomatous dermatitis of unknown etiology, were reviewed....

journal_title：Journal of cutaneous pathology

authors： Tomasini C,Moneghini L,Barbui AM

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND:Hobnail hemangioma (targetoid hemosiderotic hemangioma) is a small benign vascular tumor of the superficial and mid-dermis. In contrast to its well-characterized histology, it has been unclear whether this tumor arises from blood vessel endothelial cells (BECs) or lymphatic vessel endothelial cells (LECs). ...

journal_title：Journal of cutaneous pathology

authors： Franke FE,Steger K,Marks A,Kutzner H,Mentzel T

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:The distinction of metastatic ovarian carcinoma from other metastatic carcinomas and primary adnexal lesions in the skin is often difficult. PAX8 is a transcription factor that plays a critical role in development of the Müllerian system and has been shown to be a useful discriminatory marker between ovarian...

journal_title：Journal of cutaneous pathology

authors： Fujiwara M,Taube J,Sharma M,McCalmont TH,Kim J

更新日期：2010-09-01 00:00:00

abstract：:We reviewed the clinical, histologic, and immunofluorescence features of 20 patients with pemphigus and neoplasia and compared them with a control group of 17 patients with pemphigus without neoplasia. Patients with neoplasia were divided according to clinical, histologic, and immunofluorescence findings into those wi...

journal_title：Journal of cutaneous pathology

authors： Mehregan DR,Oursler JR,Leiferman KM,Muller SA,Anhalt GJ,Peters MS

更新日期：1993-06-01 00:00:00

abstract：:A cystic panfolliculoma is a benign follicular neoplasm which recapitulates several portions of the hair follicle. The patient was a 64-year-old Caucasian female who presented with a new growth on her right forearm. The lesion had slowly enlarged over the previous 11 months. She complained of it bleeding on several oc...

journal_title：Journal of cutaneous pathology

authors： Neill B,Bingham C,Braudis K,Zurowski S

更新日期：2016-12-01 00:00:00

abstract：:The term "nevoid malignant melanoma" (nevoid MM) is used here to describe rare nodular malignant melanomas that may escape detection in routine histological sections due to the lack of a prominent intraepidermal component, sharp lateral circumscription and evidence of partial maturation with descent in the dermis. Nev...

journal_title：Journal of cutaneous pathology

authors： McNutt NS,Urmacher C,Hakimian J,Hoss DM,Lugo J

更新日期：1995-12-01 00:00:00

abstract：:We studied two cases of pigmented neuroectodermal tumor of infancy (PNTI) by routine light microscopy and immunohistochemistry on formalin fixed, paraffin embedded tissues using antibodies to HMB-45 "melanoma associated" antigen, S-100 protein, neuron specific enolase (NSE), Leu-7 antigen, chromogranin, epithelial mem...

journal_title：Journal of cutaneous pathology

authors： Argenyi ZB,Schelper RL,Balogh K

更新日期：1991-02-01 00:00:00

abstract：:We carried out a quantitative study of the matrix and dermal papilla of the human hair follicle of the scalp, both normal and in various degrees of androgenetic alopecia. A stereological study showed the measured parameters to decrease with increase in the degree of alopecia, particularly as regards the total volume o...

journal_title：Journal of cutaneous pathology

authors： Alcaraz MV,Villena A,Pérez de Vargas I

更新日期：1993-08-01 00:00:00