Modulation of epidermal differentiation, tissue inflammation, and T-lymphocyte infilitration in psoriatic plaques by topical calcitriol.

abstract：:Many melanocytic nevi contain areas similar to nerve sheath tumors (NST) and NSTs with melanin have been described. There are some NSTs with at least partial intraneural location, including neurofibromas, plexiform neurofibromas, granular cell tumors and the recently described, dendritic cell neurofibroma with pseudor...

journal_title：Journal of cutaneous pathology

authors： Weinreb I,Labonte S,Goli H,Chetty R,Ghazarian D

更新日期：2007-12-01 00:00:00

abstract：:Proliferation of the eccrine sweat duct epithelium has been associated with skin tumors, especially keratoacanthomas and basal cell carcinomas. We report our observations on the extensive sweat gland changes in a patient who had idiopathic follicular mucinosis. ...

journal_title：Journal of cutaneous pathology

authors： Berger TG,Goette DK

更新日期：1987-06-01 00:00:00

abstract：:Two collodion baby girls with disorder evolving into lamellar ichthyosis were followed by light and electron microscopy. Light microscopically, the neonatal colloidion skin was characterized by a thick compact stratum corneum which was PAS positive in its upper two thirds, by a thin stratum granulosum and by a non-aca...

journal_title：Journal of cutaneous pathology

authors： Frenk E,Mevorah B

更新日期：1977-12-01 00:00:00

abstract：BACKGROUND:Rare cases of a non-bullous neutrophilic dermatosis occurring in patients with lupus erythematosus (LE) have been reported, often as the presenting manifestation of the disease. METHODS:We reviewed hematoxylin and eosin-stained slides and obtained clinical information from four additional patients, two of w...

journal_title：Journal of cutaneous pathology

authors： Gleason BC,Zembowicz A,Granter SR

更新日期：2006-11-01 00:00:00

abstract：:Recent advances in the understanding of the metastatic phenomenon in cancer have led to the description of a metastatic niche. This concept describes a site prepared for the tumor cells in areas frequently associated with metastasis for the individual tumor studied. This niche is a "soil" that allows for the tumor cel...

journal_title：Journal of cutaneous pathology

authors： Mihm MC Jr,Nelson JS

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:It is not clear why melanocyte disappearance occurs without fibrotic evolution in halo nevus and with fibrotic evolution in regressing melanoma. METHODS:Six halo nevi, seven regressing primary melanomas, and seven primary melanoma (PM) without regression were studied using immunohistochemistry for the pheno...

journal_title：Journal of cutaneous pathology

authors： Moretti S,Spallanzani A,Pinzi C,Prignano F,Fabbri P

更新日期：2007-04-01 00:00:00

abstract：:The rare presentation of choriocarcinoma as a cutaneous metastasis in a 23-year-old male is reported. Histological and immunohistochemical analysis of the biopsy material demonstrated two distinct cell populations, syncytiotrophoblasts and cytotrophoblasts, with syncytiotrophoblasts strongly positive for human chorion...

journal_title：Journal of cutaneous pathology

authors： Chhieng DC,Jennings TA,Slominski A,Mihm MC Jr

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:As the molecular mechanisms in melanoma chemoresistance remain unknown to date, we hypothesized these tumors to express the ATP-binding cassette (ABC) transporter G2 (ABCG2/MXR/BCRP1/ABCP1), a recently detected membrane transporter and putative stem-cell marker. Besides melanoma, we addressed the neuroendocr...

journal_title：Journal of cutaneous pathology

authors： Deichmann M,Thome M,Egner U,Hartschuh W,Kurzen H

更新日期：2005-08-01 00:00:00

abstract：:A 34-year-old man with acquired immunodeficiency syndrome presented with multiple skin lesions clinically suggestive of molluscum contagiosum. Three skin biopsy specimens were obtained which showed dermal abscesses containing multiple gram-positive cocci admixed with granular necrotic dermal material. In 2, there were...

journal_title：Journal of cutaneous pathology

authors： Boudreau S,Hines HC,Hood AF

更新日期：1988-02-01 00:00:00

abstract：:We present the case of a 77-year-old male undergoing treatment for mycosis fungoides (MF) who presented for removal of an acrochordon on his mid back. Histopathologic examination of the acrochordon revealed a dense, band-like lymphocytic inflammatory infiltrate in the dermis with epidermotropism of single lymphocytes ...

journal_title：Journal of cutaneous pathology

authors： McClain CM,Cole MB,Robbins JB,Kantrow SM

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Some examples of Bowen disease lack the characteristic broad parakeratosis making their histopathologic diagnosis particularly difficult in small and incomplete biopsies. MATERIALS AND METHODS:The archives of our dermatopathology laboratory were searched for cases of Bowen disease with >75% orthokeratosis (...

journal_title：Journal of cutaneous pathology

authors： Idriss MH,Misri R,Böer-Auer A

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Histopathologic examination is sometimes inadequate for accurate and reproducible diagnosis of certain melanocytic neoplasms. As a result, more sophisticated and objective methods have been sought. The goal of this study was to identify a gene expression signature that reliably differentiated benign and mali...

journal_title：Journal of cutaneous pathology

authors： Clarke LE,Warf MB,Flake DD 2nd,Hartman AR,Tahan S,Shea CR,Gerami P,Messina J,Florell SR,Wenstrup RJ,Rushton K,Roundy KM,Rock C,Roa B,Kolquist KA,Gutin A,Billings S,Leachman S

更新日期：2015-04-01 00:00:00

abstract：:Chronic lymphocytic leukemia (CLL/SLL) is the most common leukemia in the western world and its cutaneous dissemination a very uncommon phenomenon. Lymphomatoid papulosis (LyP) is a CD30+ lymphoproliferative disorder characterized by chronic, recurrent and self healing skin lesions. Up to 20% of patients with LyP have...

journal_title：Journal of cutaneous pathology

authors： Hibler J,Salavaggione AL,Martin A,Gru AA

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Although a range of cytomegalovirus (CMV)-induced cutaneous manifestations is described in AIDS patients, skin involvement in immunocompromised patients is rare, and intraneural CMV inclusions or CMV neuritis has not been documented in skin biopsies. METHODS AND RESULTS:Cutaneous biopsies of CMV lesions wer...

journal_title：Journal of cutaneous pathology

authors： Ramdial PK,Dlova NC,Sydney C

更新日期：2002-08-01 00:00:00

abstract：:Sarcoidosis is a granulomatous condition with diverse clinical presentations, including neurological findings. It was previously hypothesized that perineural sarcoidal granulomas in the skin may be an explanation of small-fiber neuropathy. Herein, we present a case of a 55 year old female with anesthetic cutaneous les...

journal_title：Journal of cutaneous pathology

authors： Kazi R,Kazlouskaya V,Ho J,Karunamurthy A

更新日期：2020-07-01 00:00:00

abstract：:This is the first report of spinous and follicular lichen nitidus associated with perifollicular granuloma formation. Clinicians and pathologists need to distinguish this stage of the disease from lichen scrofulosorum. ...

journal_title：Journal of cutaneous pathology

authors： Madhok R,Winkelmann RK

更新日期：1988-08-01 00:00:00

abstract：:The development of cancer involves epithelial-stromal interactions. Alterations in the synthesis and deposition of type I and III collagens are related to the tumor morphology. Skin carcinogenesis in experimental animals provides a reliable model for the development of neoplasia. Ultraviolet (UV) irradiation is the ma...

journal_title：Journal of cutaneous pathology

authors： Stenbäck F,Mäkinen MJ,Jussila T,Kauppila S,Risteli J,Talve L,Risteli L

更新日期：1999-08-01 00:00:00

abstract：:Benign lymphangioendothelioma is a rare locally infiltrative vascular neoplasm, presenting as a slow-growing, asymptomatic, reddish-violaceous plaque. Histopathologically, it is characterized by irregular and thin-walled vascular spaces, lined by a single and discontinuous layer of flat endothelial cells, dissecting d...

journal_title：Journal of cutaneous pathology

authors： Revelles JM,Díaz JL,Angulo J,Santonja C,Kutzner H,Requena L

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:The distinction of metastatic ovarian carcinoma from other metastatic carcinomas and primary adnexal lesions in the skin is often difficult. PAX8 is a transcription factor that plays a critical role in development of the Müllerian system and has been shown to be a useful discriminatory marker between ovarian...

journal_title：Journal of cutaneous pathology

authors： Fujiwara M,Taube J,Sharma M,McCalmont TH,Kim J

更新日期：2010-09-01 00:00:00

abstract：:Two patients with solitary lesions of pagetoid reticulosis are presented. A third case with disseminated lesions and similar microscopic detail is also reported. Lighg microscopic findings include an abnornal cell infiltrate confined to the epidermis and distributed diffusely in a pagetoid pattern. In ultrathin sectio...

journal_title：Journal of cutaneous pathology

authors： Wood WS,Killby VA,Stewart WD

更新日期：1979-04-01 00:00:00

abstract：:In past years, association of primary cutaneous B-cell lymphoma (CBCL) with infection by Borrelia burgdorferi has been reported in a few patients. The evidence for a pathogenetic role was based on clinical grounds or raised titre of antibodies in serum. Both methods, however, do not prove the association between the m...

journal_title：Journal of cutaneous pathology

authors： Cerroni L,Zöchling N,Pütz B,Kerl H

更新日期：1997-09-01 00:00:00

abstract：:The basal cell adhesion molecule (B-CAM) is a 90-kD cell surface glycoprotein with a characteristic immunoglobulin domain structure. The pattern of B-CAM expression in cultured cells suggests that the molecule is associated with a substrate-adherent growth pattern in some lineages. We investigated the expression of B-...

journal_title：Journal of cutaneous pathology

authors： Bernemann TM,Podda M,Wolter M,Boehncke WH

更新日期：2000-03-01 00:00:00

abstract：:The arrector pili (AP) muscle is a small band of smooth muscle that attaches proximally to the bulge area of the pilosebaceous apparatus in the reticular dermis and extends up toward the epidermis. The distal anatomy of the AP and the anchorage mechanism allowing hair erection have not been previously described. Integ...

journal_title：Journal of cutaneous pathology

authors： Mendelson JK,Smoller BR,Mendelson B,Horn TD

更新日期：2000-02-01 00:00:00

abstract：:Traditionally, melanoma has been considered by surgeons to be a highly lethal malignancy, always requiring a radical surgical approach for optimal chance of cure. Yet melanoma patients who are now being referred for treatment frequently have small early lesions, and surgeons should develop a flexible attitude about ma...

journal_title：Journal of cutaneous pathology

authors： Patterson WB

更新日期：1979-06-01 00:00:00

abstract：BACKGROUND:Merkel cell carcinoma (MCC) is an aggressive neoplasm, which is often associated with Merkel cell polyomavirus (MCPyV). Programmed death-1 (PD-1) and its ligand PD-L1 are key players of the tumor microenvironment (TME). METHODS:Fourteen paraffin-embedded tissue samples of MCC were stratified by their MCPyV ...

journal_title：Journal of cutaneous pathology

authors： Mitteldorf C,Berisha A,Tronnier M,Pfaltz MC,Kempf W

更新日期：2017-09-01 00:00:00

abstract：:A malignant pilomatricoma is described in a dog. The primary tumor apparently developed in the metatarsal area where there were multiple intradermal skin nodules. Lymphatic invasion by tumor cells resulted in metastasis to the mammary glands, lymph nodes and lungs. The tumor is compared to the pilomatricoma in man whe...

journal_title：Journal of cutaneous pathology

authors： Goldschmidt MH,Thrall DE,Jeglum KA,Everett JI,Wood MG

更新日期：1981-10-01 00:00:00

abstract：:The present study was undertaken to characterize further the structure and function of cutaneous nerves which we have previously shown to associate with skin immune cells (Hosoi et al., Nature 1993: 363:159). Ultrastructurally, axons were prominent within the superficial dermis and epidermis in neonatal murine skin, b...

journal_title：Journal of cutaneous pathology

authors： Egan CL,Viglione-Schneck MJ,Walsh LJ,Green B,Trojanowski JQ,Whitaker-Menezes D,Murphy GF

更新日期：1998-01-01 00:00:00

abstract：:Confocal laser scanning microscopy (CLSM) is a new optical microscopic technique, which offers significant advantages over conventional microscopy. CLSM is microscopy of optical sections. Light, which is emitted from regions other than the focal plane, is cut off by introducing a diaphragm in the beam path. The result...

journal_title：Journal of cutaneous pathology

authors： Fink-Puches R,Hofmann-Wellenhof R,Smolle J,Kerl H

更新日期：1995-06-01 00:00:00

abstract：:Myxofibrosarcomas (MFSs) are sarcomas most commonly seen in older patients. These are tumors of deep soft tissue seen in subcutaneous tissue and deep fascia, with frequent muscle involvement. These sarcomas are notorious for recurrences and progression to a higher grade with notable metastatic potential. They are very...

journal_title：Journal of cutaneous pathology

authors： Singh A,Brar RK,Dey B,Nigam J,Deshpande A

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:The migration of circulating monocytes into the dermis is considered to be essential for both the initiation and the progression of xanthoma. The contribution of vascular endothelial cells to the migration process is unclear. METHODS:Twenty cases of xanthelasma and six cases of tuberous xanthoma lesions wer...

journal_title：Journal of cutaneous pathology

authors： Matsumoto M,Kunimitsu S,Wada K,Ikeda M,Yokogawa M,Keyama A,Kodama H

更新日期：2007-10-01 00:00:00