Abstract：
:The use of antibodies to alpha-(17--39) ACTH, beta-LPH, and alpha- and beta-endorphins has enabled the detection of immunoreactive cells as early as the eight week of fetal life. Immunoreactive cells are located in the anterior and intermediate lobes of the pituitary gland in normal human fetuses. The same cells reacted with different antisera used in the present study. No immunoreactive cells were observed in the posterior lobe. The specificity of the immunocytological reaction has been controlled. In seven anencephalic fetuses, the presence of immunoreactive cells suggests that ACTH and beta-LPH can originate from a common precursor and are synthesized independent of the hypothalamus.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Bégeot M,Dubois MP,Dubois PMdoi
10.1007/BF00225339subject
Has Abstractpub_date
1978-10-30 00:00:00pages
413-22issue
3eissn
0302-766Xissn
1432-0878journal_volume
193pub_type
杂志文章abstract：:NdWFamide is an Aplysia cardioexcitatory tri-peptide containing D-tryptophan. To investigate the roles of this peptide, we examined the immunohistochemical distribution of NdWFamide-positive neurons in Aplysia tissues. All the ganglia of the central nervous system (CNS) contained NdWFamide-positive neurons. In particu...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-003-0707-3
更新日期：2003-04-01 00:00:00
abstract：:The reactivity of rat lymph node macrophages and reticulum cells has been studied in relation to the course of the immune response. Special attention was paid to the interdigitating cells (IDC) in the paracortex and the dendritic reticulum cells (DRC) in the germinal centre. Different types of macrophage predominate i...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00231019
更新日期：1978-08-25 00:00:00
abstract：:We have previously shown that immunoneutralization of transforming growth factor-beta (TGF-beta) in the chick embryo significantly reduces programmed cell death (PCD) in peripheral neurons, spinal cord, and retina. In order to validate these results we have begun to analyze PCD in mice with targeted ablations of the T...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-003-0761-x
更新日期：2003-07-01 00:00:00
abstract：:The inositol 1,4,5-trisphosphate receptor (IP3R) is an intracellular Ca2+ release channel responsible for mobilizing stored Ca2+. Three different receptor types have been molecularly cloned, and their genes have been classified into a family. The gene for the type 1 receptor (IP3R1) is predominantly expressed in cereb...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00307790
更新日期：1995-05-01 00:00:00
abstract：:Vesicular transport involves SNARE (soluble- N-ethylmaleimide-sensitive-factor-attachment-protein-receptor) proteins on transport vesicles and on target membranes. Syntaxin 13 is a SNARE enriched in brain, associated with recycling endosomes; its overexpression in PC12 cells promotes neurite outgrowth. This suggests a...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-002-0600-5
更新日期：2002-08-01 00:00:00
abstract：:Peeling skin syndrome is a heterogeneous group of rare disorders. Peeling skin, leukonychia, acral punctate keratoses, cheilitis and knuckle pads (PLACK syndrome, OMIM616295) is a newly described form of PSS with an autosomal recessive mode of inheritance. We report a 5.5-year-old boy with features of PLACK syndrome. ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-019-03077-9
更新日期：2019-11-01 00:00:00
abstract：:Considerable evidence indicates that the state of ocular connective tissues and their response in glaucomatous disease affect the degree of glaucoma damage. Both experimental and clinical data suggest that improved diagnostic and prognostic information can be derived from the assessment of the mechanical responsivenes...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-013-1603-0
更新日期：2013-08-01 00:00:00
abstract：:Somatostatin-like immunoreactivity was localized in nerve cell bodies and nerve terminals in the cat coeliac ganglion. Two types of somatostatin-immunoreactive cell bodies were revealed, the first being large (diameter 35 microns), numerous and weakly labelled, whereas the second was considerably smaller (diameter 10....
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00327290
更新日期：1991-03-01 00:00:00
abstract：:Mlh1 is a member of DNA mismatch repair (MMR) machinery and is also essential for the stabilization of crossovers during the first meiotic division. Recently, we have shown that zebrafish mlh1 mutant males are completely infertile because of a block in metaphase I, whereas females are fertile but have aneuploid progen...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-007-0550-z
更新日期：2008-04-01 00:00:00
abstract：:The bilaterally paired cercal nerves of Archimantis brunneriana Sauss. leave the terminal ganglion posteriorly and then turn dorsally through muscles at the rear of the abdomen to enter the cerci, where each splits into two branches; successive branchings occur further distally in each cercus. In the distal nerve bran...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00217267
更新日期：1982-01-01 00:00:00
abstract：:Bone marrow (BM) from human and rodent species contains a population of multipotential cells referred to as mesenchymal stem cells (MSCs). Currently, MSCs are isolated indirectly by using a culture step and then the generation of fibroblast colony-forming units (CFU-fs). Unprocessed or native BM MSCs have not yet been...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-006-0292-3
更新日期：2007-03-01 00:00:00
abstract：:Tactile hairs on the locust thorax can be divided into two classes by their external morphology and their central projection pattern: Short hairs, 10--100 micrometer in length, which are assembled in distinct plates and rows, and long hairs, 100--800 micrometer in length, which are distributed all over the body and ar...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00234546
更新日期：1981-01-01 00:00:00
abstract：:The size, density and total number of neuroepithelial bodies (NEB) in the lungs of late fetal, neonatal, and mature rabbits were determined using fluorescence microscopy. In this study lungs from 27-, 29-, 30-, and 31-day fetuses; neonates of ages 2, 7, and 30 days; and 4- and 7(+)-month-old rabbits, were used. The to...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219875
更新日期：1984-01-01 00:00:00
abstract：:Post-translational modification of histone proteins, such as the methylation of lysine and arginine residues, influences the higher order of chromatin and leads to gene activation or silencing. Histone methyltransferases or demethylases actively add or remove various methylation marks in a cell-type-specific and conte...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-014-1842-8
更新日期：2014-06-01 00:00:00
abstract：:Large granular lymphocytes (LGL) comprise a natural defense system in the liver and exert an inhibitory effect on tumor cell metastasis. In order to demonstrate the maturation of LGL in the liver from the morphological aspect, we evaluated electron-microscopically the frequency of 0.2 micron vesicles (rod-cored and "e...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00354799
更新日期：1994-04-01 00:00:00
abstract：:We present an experimental method allowing the production of three-dimensional organ-like structures, namely microtissues (MTs), in vitro without the need for exogenous extracellular matrix (ECM) or growth factors. Submandibular salivary glands (embryonic day ED14), kidneys (ED13) and lungs (ED13) were harvested from ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-016-2487-6
更新日期：2016-12-01 00:00:00
abstract：:It is clear that the well-described phenomenon of epithelial-mesenchymal transition (EMT) plays a pivotal role in embryonic development, wound healing, tissue regeneration, organ fibrosis and cancer progression. EMTs have been classified into three subtypes based on the functional consequences and biomarker context in...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-011-1227-1
更新日期：2012-01-01 00:00:00
abstract：:Since the advent of transmission electron microscopy of tissues capable of growth and regeneration, cell and developmental biologists have postulated that the undifferentiated cells observed within these tissues represent tissue-specific stem or progenitor cells. However, no studies have addressed the issue of whether...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-002-0641-9
更新日期：2002-12-01 00:00:00
abstract：:Growing numbers of translational genomics studies are based on the highly efficient and versatile zebrafish (Danio rerio) vertebrate model. The increasing types of zebrafish models have improved our understanding of inherited kidney diseases, since they not only display pathophysiological changes but also give us the ...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-017-2593-0
更新日期：2017-07-01 00:00:00
abstract：:Mouse milk fat globule-EGF factor 8, MFG-E8, is the ortholog to the human mammary tumor marker, lactadherin, and comprises two spliced variants, the L and S forms. Recent studies have suggested that MFG-E8-L produced by macrophages and Langerhans cells in the skin serves as a linker between phagocytic cells and apopto...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-005-1148-y
更新日期：2005-08-01 00:00:00
abstract：:The blood-brain barrier (BBB) protects the brain from toxic substances within the bloodstream and keeps the brain's homeostasis stable. On the other hand, it also represents the main obstacle in the treatment of many CNS diseases. Among different techniques, nanoparticles have emerged as promising tools to enhance bra...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-014-1819-7
更新日期：2014-03-01 00:00:00
abstract：:The ultrastructure of the seminiferous tubules was studied in rats that had been subjected to whole body irradiation on the 19th day of gestation. The seminiferous tubules from 3 months-old irradiated animals are devoid of germ cells and contain only Sertoli cells. Compared with controls of the same age, the seminifer...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218294
更新日期：1982-01-01 00:00:00
abstract：:Rectal prolapse is associated with diminished anal sensitivity and rectal motor activity. Both sensory and motor functions are controlled by the extrinsic and intrinsic (enteric nervous system) innervation of the gastrointestinal tract. Studies of changes in intestinal innervation in humans and in animal models with r...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-016-2465-z
更新日期：2016-11-01 00:00:00
abstract：:Light and electron microscopic studies, including the use of the vital dyes trypan blue and acridine orange, indicate that the topical application of precocene II rapidly triggers degenerative processes in the corpora allata (CA) leading within a few days to the virtual disappearance of the parenchymal cells of these ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00234326
更新日期：1979-11-01 00:00:00
abstract：:In fresh-water turtles, the bridge connecting the proximal and caudal stumps of transected spinal cords consists of regenerating axons running through a glial cellular matrix. To understand the process leading to the generation of the scaffold bridging the lesion, we analyzed the mitotic activity triggered by spinal i...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-011-1173-y
更新日期：2011-06-01 00:00:00
abstract：:The ultrastructure of the sinus gland of the fiddler crab, Uca pugnax, was investigated and found to be similar to that in other crustaceans. Five types of neurosecretory axon terminals were tentatively identified on the basis of the size, shape, and electron density of granules within the axons. Release of neuro-secr...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00222805
更新日期：1975-12-29 00:00:00
abstract：:The fine structure of the main excretory duct epithelium (MEDE) of female mouse submandibular gland was investigated by scanning and transmission electron microscopy and the results compared with the previously established structure of male mouse MEDE. A comparative analysis of the subepithelial capillaries of both se...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00300213
更新日期：1994-09-01 00:00:00
abstract：:Gill lamellae of a bivalve Anodonta woodiana lauta (v. Martens) were observed by electron microscopy. The Anodonta gill wall consists of a single layer of epithelial cells, its basal lamina and the underlying connective tissue layer. It was confirmed that there is no true endothelium in the vessels and that the connec...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00222069
更新日期：1975-01-01 00:00:00
abstract：:Uptake of uteroglobin (UGL) by day-6 rabbit blastocysts and the intracellular fate of this protein were studied by light- and electron-microscopic autoradiography, immunocytochemistry and acid-phosphatase cytochemistry. UGL, labelled with N-succinimidyl-(2-3-3H)-propionate, was administered to embryos in vitro for 25 ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00305254
更新日期：1990-12-01 00:00:00
abstract：:Nervous elements in the periodontal ligament and dental pulp of rat incisors were investigated by means of immunohistochemistry for neurofilament protein (NFP) and glia-specific S-100 protein. The periodontal ligament in the incisors was densely innervated by NFP-immunoreactive nerve fibers; the distribution of the ne...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215442
更新日期：1988-01-01 00:00:00
