Abstract:
:The fine structure of the main excretory duct epithelium (MEDE) of female mouse submandibular gland was investigated by scanning and transmission electron microscopy and the results compared with the previously established structure of male mouse MEDE. A comparative analysis of the subepithelial capillaries of both sexes was also performed. In this pseudostratified epithelium, principal cell-types were observed: types-I, -II, -III and basal cells. This differed significantly from male MEDE, where type-II and -III are absent and type-I cells are the most numerous. The latter cell-type had abundant mitochondria, a few lipid-containing granules, lysosomes in the infra-nuclear cytoplasm and well-developed basal infoldings. These cells were also characterized by abundant glycogen granules throughout the cytoplasm, many profiles of strands of smooth endoplasmic reticulum in the apical region, and lysosomes in the infranuclear region. Type-II cells were the second most numerous. Their most characteristic features were the presence of tubular vesicles which appeared to be invaginated from the plasma membrane, RER, SER, free ribosomes, a few peroxisomes with nucleoids, and primary lysosomes in extremely light cytoplasm. They had many mitochondria throughout the cytoplasm, except in the apical region, a few lipid-containing granules and no basal infoldings. Type-III cells were very few and were characterized by well developed basal infoldings, abundant free ribosomes, RER, SER, vesicles containing moderately dense material, and many lipid-containing granules. They also had many mitochondria throughout the cytoplasm, except apically. Basal cells had a large nucleus and the cytoplasm had few organelles.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Sato A,Goto F,Miyoshi Sdoi
10.1007/BF00300213subject
Has Abstractpub_date
1994-09-01 00:00:00pages
407-15issue
3eissn
0302-766Xissn
1432-0878journal_volume
277pub_type
杂志文章abstract::Successful embryo implantation depends on intricate epithelial-stromal cross-talk. However, molecular modulators involved in this cellular communication remain poorly elucidated. Using multiple approaches, we have investigated the spatiotemporal expression and regulation of serine protease inhibitor Kazal type 3 (SPIN...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-010-1013-5
更新日期:2010-09-01 00:00:00
abstract::It is clear that the well-described phenomenon of epithelial-mesenchymal transition (EMT) plays a pivotal role in embryonic development, wound healing, tissue regeneration, organ fibrosis and cancer progression. EMTs have been classified into three subtypes based on the functional consequences and biomarker context in...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-011-1227-1
更新日期:2012-01-01 00:00:00
abstract::The distribution of the glycoprotein, mucin 1 (MUC1), was determined in lactating guinea-pig mammary tissue at the resolution of the electron microscope. MUC1 was detected on the apical plasma membrane of secretory epithelial cells, the surface of secreted milk-fat globules, the limiting membranes of secretory vesicle...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410100351
更新日期:2001-04-01 00:00:00
abstract::The vascularization of the hypothalamo-adenohypophysial region of the toad Bufo bufo (L.) (Amphibia, Anura) was studied by means of light- and scanning electron microscopy. Special attention was given to the portal vascular system of the median eminence and the pars distalis. Course and arrangement of these vessels ar...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00223268
更新日期:1975-09-16 00:00:00
abstract::We investigated the binding characteristics of two monoclonal antibodies, 4F3 and 3F8, which in the retina specifically stain Müller cells, both with protein blots and immunohistochemically in sections of various regions of the central nervous system of neonatal and adult cats and rats. Clear differences emerged betwe...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050887
更新日期:1997-09-01 00:00:00
abstract::Although several studies have shown a dysregulation of microRNA (miRNA) expression profiles in cutaneous melanoma, there has been little research on the miRNA machinery itself. In this study, we investigated the mRNA expression profiles of different miRNA machinery components in primary cutaneous malignant melanoma (P...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-012-1446-0
更新日期:2012-10-01 00:00:00
abstract::Evidence has already been adduced suggesting that an increase in microtubular number occurs in the tractus hypophyseus of rats stressed by the administration of hypertonic saline, and of rats with congenital diabetes insipidus (CDI). Since the tractus hypophyseus in these animals shows high secretory activity, it seem...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219611
更新日期:1976-06-28 00:00:00
abstract::Cobaltous-lysine is transported anterogradely from the optic nerve of the teleost, Lethrinus chrysostomus (Lethrinidae, Perciformes). The marginal optic tract is labelled in longitudinal bands of light and dark staining fibres which persists caudally within the ventral division but not in the dorsal division. This spe...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218889
更新日期:1989-01-01 00:00:00
abstract::The distribution and synaptic connections of the indoleamine-accumulating neurons in the retinae of the goldfish and carp were studied by means of fluorescence and electron microscopy. The indoleamine-accumulating neurons were visualized after intravitreal injection and uptake of the indoleamine 5,6-dihydroxytryptamin...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:
更新日期:1983-01-01 00:00:00
abstract::Spinal cord injury (SCI) is a major cause of paralysis, disability and even death in severe cases. Lithium has neuroprotective effects on SCI, while the underlying mechanisms remain obscure. In the present study, we established a SCI rat model, which subsequently received lithium treatment. Results displayed that lith...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-020-03298-3
更新日期:2021-01-19 00:00:00
abstract::Acute necrotizing pancreatitis (ANP) is a common gastrointestinal cause of emergency admissions in dogs and humans and can lead to a systemic inflammatory response syndrome resulting in multiple organ dysfunction syndrome. Among the various complications associated with ANP, acute lung injury (ALI) or acute respirator...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-020-03211-y
更新日期:2020-05-01 00:00:00
abstract::Whole pigs lenses were fixed, critical-point dried and fractured, and the internal surfaces examined with a scanning electron microscope. At various locations from the equator to the center of the lens four types of fibers can be distinguished. The superficial fibers have small interdigitations. Cortical lens fibers, ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00217281
更新日期:1982-01-01 00:00:00
abstract::The three-dimensional architecture of the lamina propria in the jejunal mucosa of the rat was studied by scanning electron microscopy. The lamina propria is a typical reticular tissue with fine nets of reticular fibers and free and fixed cells lying among them. However, the lamina propria in the core of villi displaye...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00225563
更新日期:1985-01-01 00:00:00
abstract::Chondrocytes were isolated enzymatically from rabbit ear cartilage, grown in vitro or as autotransplants for 1, 2 or 5 weeks and then examined by transmission electron microscopy. A confluent monolayer formed rapidly in vitro and the cells later grew in multiple overlapping layers, producing thick sheets of cartilagin...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00227600
更新日期:1977-05-31 00:00:00
abstract::We used immunohistochemistry to identify cells present in pituitary allografts in the hamster. Hypophyses removed from neonatal hamsters or adenohypophyses removed from adult females were placed beneath renal capsules of hypophysectomized adult females. Serum PRL, LH, and GH concentrations were measured at two, five a...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00215467
更新日期:1988-01-01 00:00:00
abstract::Follicular dendritic cells (FDCs) are immune accessory cells found in the follicles of secondary lymphoid organs where they promote B cell maturation in germinal centers (GCs) that develop following antigen exposure. Recently, we published a method for isolating functional murine FDCs in high purity. We reasoned that ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-007-0566-4
更新日期:2008-04-01 00:00:00
abstract::Developmental alterations of paranodal fiber segments have not been investigated systematically in human nerve fibers at the light- and electron-microscopic level. We have therefore analyzed developmental changes in the fine structure of the paranode in 43 human sural nerves during the axonal growth period up to 5 yea...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00333704
更新日期:1993-09-01 00:00:00
abstract::Recent advances in the ability to culture the hepatic forms of mammalian malaria parasites, particularly of the important human pathogen Plasmodium falciparum have provided novel opportunities to study the ultrastructural organisation of the parasite in its natural host cell the human hepatocyte. In this electron-micr...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219210
更新日期:1986-01-01 00:00:00
abstract::This investigation provides histochemical evidence for lysosomal storage of sulfated glycosaminoglycans (GAGs) in the interstitial cells of the renal cortex and in macrophage-like cells of the renal medullary zones of rats chronically treated with the drug tilorone. This compound is known to interfere with lysosomal d...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218958
更新日期:1987-12-01 00:00:00
abstract::The submandibular gland (SMG) is a tissue that can be regenerated in a tissue injury model and that has adult stem cells capable of self-renewal and differentiation into functional cells. We have analyzed the localization of label-retaining cells (LRCs), which are putative progenitor cells, by using the BrdU-labeling ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-008-0667-8
更新日期:2008-10-01 00:00:00
abstract::Retinae of Abyssinian cats homozygous for a retinal degeneration gene, and normal controls, have been investigated using antibodies directed against opsin, transducin alpha (TD-alpha), S-antigen (48K protein), interphotoreceptor retinoid-binding protein (IRBP), and cone outer segments. IRBP-immunoreactivity (IR) is mu...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00221474
更新日期:1989-09-01 00:00:00
abstract::We have previously shown that the chromogranin A (CgA)-derived peptide catestatin (CST: hCgA352-372) inhibits nicotine-induced secretion of catecholamines from the adrenal medulla and chromaffin cells. In the present study, we seek to determine whether CST regulates dense core (DC) vesicle (DCV) quanta (catecholamine ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-018-2956-1
更新日期:2019-04-01 00:00:00
abstract::Brain injuries trigger physiological reactions which are mediated by a number of cytokines including interleukin-6 (IL-6), ciliary neurotrophic factor (CNTF), and leukemia inhibitory factor (LIF). Astrocytes and microglia, the protagonists in these traumatic responses, are known to secrete a variety of paracrine signa...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-002-0624-x
更新日期:2002-11-01 00:00:00
abstract::Kruppel-like factor 4 (KLF4) is a zinc-finger-type transcription factor with a restricted expression pattern during skeletal development. We have previously shown that KLF4 represses osteoblast mineralization concomitant with a down-regulation in the expression of a number of osteoblastic genes, both in vivo and in vi...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-014-1931-8
更新日期:2014-10-01 00:00:00
abstract::Interstitial cells in the myenteric plexus and the deep muscular plexus of the small intestine of the c-kit mutant rats (Ws/Ws) and their normal siblings (+/+) were studied. c-Kit immunoreactivity was detected in two regions corresponding to the myenteric plexus and the deep muscular plexus in the jejunum of +/+ rats,...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410051119
更新日期:1998-08-01 00:00:00
abstract::The present communication describes an investigation of stimulation and inhibition of delta 5-3 beta-hydroxysteroid dehydrogenase in interrenal glands of tadpoles of Rana catesbeiana. Frozen sections of interrenal glands, together with kidneys, were prepared histochemically for assay of delta 5-3 beta-HSD activity. Co...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218950
更新日期:1987-12-01 00:00:00
abstract::The effects of thyroidectomy, adrenalectomy, and castration on the pars distalis of male Japanese quail, and of injection of LH-RH on sexually inactive females, were investigated by light and electron microscopy. Correlation between light and electron microscopy was attained by use of alternate thin and thick sections...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219152
更新日期:1975-06-09 00:00:00
abstract::It is possible to determine statistically the repartitions of shapes or sizes in a population of particles from the recurrence of shapes or sizes of their outlines in microscopical sections. This method was applied to a population of 1326 follicular profiles randomly sampled from 30 ovaries of pubescent homozygous "Nu...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219416
更新日期:1976-07-30 00:00:00
abstract::The effects of the administration of thyroxine (T4) on the postnatal cytodifferentiation of granular convoluted tubule (GCT) cells of the submandibular gland (SMG) of Lewiss-Webster mice were studied by light and electron microscopy. From birth, mice of both sexes were injected daily with T4 (sc 0.4 micrograms/g BW) a...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218202
更新日期:1987-05-01 00:00:00
abstract::The endoneurial collagen sheath around teased nerve fibres following crush injury was studied by scanning electron microscopy and compared with uninjured sciatic nerve fibres and with fibres from the dystonic mutant mouse. Following crush injury the endoneurial collagen became more abundant than seen in untreated nerv...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00210469
更新日期:1981-01-01 00:00:00