Development of diagnostic and treatment strategies for glaucoma through understanding and modification of scleral and lamina cribrosa connective tissue.

abstract：:Receptors for advanced glycation end-products (RAGE) are members of the immunoglobulin superfamily of cell-surface receptors implicated in mechanisms of pulmonary inflammation. In the current study, we test the hypothesis that RAGE mediates inflammation in primary alveolar macrophages (AMs) exposed to diesel particula...

journal_title：Cell and tissue research

authors： Barton DB,Betteridge BC,Earley TD,Curtis CS,Robinson AB,Reynolds PR

更新日期：2014-10-01 00:00:00

abstract：:The ultrastructure of the contractile apparatus of the rat soleus muscle during the course of denervation atrophy was investigated. It was found that the ratio of thin the thick filaments increased in myofibrils of atrophying muscle fibers. Elevation of the ratio was observed as early as the second day after denervati...

journal_title：Cell and tissue research

authors： Jakubiec-Puka A,Kulesza-Lipka D,Krajewski K

更新日期：1981-01-01 00:00:00

abstract：:Two different fixative procedures (immersion and perfusion) and four different fixative solutions were used in order to obtain the best preservation of the brush cells of the common bile duct of the rat. The results indicate that only perfusion fixation through the common bile duct is suitable, independent of the fixa...

journal_title：Cell and tissue research

authors： Luciano L,Castellucci M,Reale E

更新日期：1981-01-01 00:00:00

abstract：:The cellular response of non-neuronal elements of the pyramidal cell layer of the rat hippocampus, especially the area CA3, was observed electron microscopically following destruction of this formation by means of intraventricular administration of kainic acid (KA). The neuroglial cell types responding to the KA-induc...

journal_title：Cell and tissue research

authors： Murabe Y,Ibata Y,Sano Y

更新日期：1981-01-01 00:00:00

abstract：:Pituitaries from normal, young and adult male rats were fixed either in sublimate-formalin or in glutaraldehyde-osmium. In adjacent Paraplast sections, almost all the gonadotrophs were immunostained with both LH and FSH antisera. The rat LH beta and FSH antisera used were shown to be highly specific by the absorption ...

journal_title：Cell and tissue research

authors： Yoshimura F,Nogami H,Shirasawa N,Yashiro T

更新日期：1981-01-01 00:00:00

abstract：:NCS-1 (neuronal calcium sensor) is a recently characterized member of a highly conserved neuron-specific family of calcium-binding proteins, which also includes frequenin and recoverin. The cellular and subcellular distributions of NCS-1 in the rat nervous system were investigated using light- and electron-microscopic...

journal_title：Cell and tissue research

authors： Martone ME,Edelmann VM,Ellisman MH,Nef P

更新日期：1999-03-01 00:00:00

abstract：:The midgut cells of Tomocerus minor (Insecta, Collembola) were examined with the electron microscope and cytochemically. The midgut epithelium consists of a series of cells characterised by numerous mineral concretions scattered throughout the cytoplasm. Mitochondria are abundant; microvilli are well developed at the ...

journal_title：Cell and tissue research

authors： Humbert W

更新日期：1979-01-30 00:00:00

abstract：:Ossification of calvariae from day-21 rat fetuses was reinvestigated by electron microscopy using different fixation techniques (glutaraldehyde/OsO4, tannic acid, ruthenium red, K-pyroantimonate). An osteoid layer with scattered mineral deposits was found at the mineralization front. Directly beyond this layer, a shee...

journal_title：Cell and tissue research

authors： Zimmermann B

更新日期：1992-01-01 00:00:00

abstract：:Retinitis pigmentosa is a blinding disease in which unknown mechanisms cause the degeneration of retinal photoreceptors. The retinal degeneration (rd1) mouse is a relevant model for this condition, since it carries a mutation also found in some forms of retinitis pigmentosa. To understand the degenerative process in t...

journal_title：Cell and tissue research

authors： Johnson LE,van Veen T,Ekström PA

更新日期：2005-05-01 00:00:00

abstract：:Neuroblastoma cells grown on substrates in culture develop long processes and assume the morphology of normal neurons as judged light microscopically. The development of synapses in the cultured tissue is studied by periodic electron microscopic examination of the areas of contact between cells. The initial explants a...

journal_title：Cell and tissue research

authors： Spoerri PE,Glees P,Dresp W

更新日期：1980-01-01 00:00:00

abstract：:The mechanism of cell death which occurs during Chagas' cardiopathy is disputed. To address this issue we analyzed the molecular pathways implicated in the death of cardiomyocytes during T. cruzi invasion and found that they undergo apoptosis during both in vitro and in vivo infections. However, the death rates and on...

journal_title：Cell and tissue research

authors： de Souza EM,Araújo-Jorge TC,Bailly C,Lansiaux A,Batista MM,Oliveira GM,Soeiro MN

更新日期：2003-11-01 00:00:00

abstract：:Connective tissue microfibrils were observed in tissues prepared with methods believed to minimize the loss of tissue components. The eyes of C57BL/6J mice were fixed with glutaraldehyde followed by either freeze substitution, or embedding in glycol methacrylate, a water-miscible embedding medium, after limited or no ...

journal_title：Cell and tissue research

authors： Inoue S

更新日期：1995-02-01 00:00:00

abstract：:Previous studies have revealed a remarkable capacity of intracerebral grafts of embryonic brain tissue to establish extensive axonal connections with denervated areas in the brains of adult rats. In the present study we have explored the possibilities of using grafts in the spinal cord to substitute for the loss of no...

journal_title：Cell and tissue research

authors： Nornes H,Björklund A,Stenevi U

更新日期：1983-01-01 00:00:00

abstract：:VIP-containing neurons were localized in lungs from dogs, cat, and human subjects by means of the indirect immunofluorescence technique. Nerve fibers and terminals were observed in the smooth muscle layer and glands of airways, and within the walls of pulmonary and bronchial vessels, especially at the medial-adventiti...

journal_title：Cell and tissue research

authors： Dey RD,Shannon WA Jr,Said SI

更新日期：1981-01-01 00:00:00

abstract：:Our immunocytochemical investigation of the magnocellular neuroendocrine system in the goldfish hypothalamus reveals enkephalin (ENK)-containing neurons interspersed among the vasotocin (VT)- and isotocin (IT)-containing neurons of the preoptic nucleus. The perikarya of the ENK, VT, and IT neurons do not show distinct...

journal_title：Cell and tissue research

authors： Reaves TA Jr,Hayward JN

更新日期：1979-08-03 00:00:00

abstract：:The kidney is an organ involved in cross talk with many human organs. The link between the immune system and the kidney has been studied in some detail, although data precisely elucidating their interaction are sparse, in particular with regard to the function of the kidney filter apparatus. Current research suggests ...

journal_title：Cell and tissue research

authors： Hahm E,Peev V,Reiser J

更新日期：2017-07-01 00:00:00

abstract：:Filamentous intranuclear rodlets were found in a majority of cells in a bronchiolar neuroepithelial body of a rabbit. These rodlets appear to be similar to structures that have been described primarily in neural tissues. They are composed of large bundles of microfibrils made up of smaller subbundles. No close associa...

journal_title：Cell and tissue research

authors： El-Bermani AW,Montvilo JA,Bloomquist EI

更新日期：1981-01-01 00:00:00

abstract：:Over the past decade, adult stem cells have attracted great attention because of their ability to potentially regenerate desired tissues or entire organs. With the emergence of nanomaterial-based gene therapy, adult stem cells have been considered as a proper tool for the biomedical field. In this study, we utilized o...

journal_title：Cell and tissue research

authors： Liang H,Duan W,Hou H,Yi W,Zhang J,Jin Z,Zhai M,Yu S,Liu J,Yi D

更新日期：2015-12-01 00:00:00

abstract：:Intercellular junctions in the young mouse ovary were examined by electron microscopy utilizing freeze-fracture and thin-sectioning techniques. Projections from the granulosa cells adjacent to the oocyte (GI) traverse the zona pellucida and form small gap junctions on the oocyte surface. On the P-face of these cells, ...

journal_title：Cell and tissue research

authors： Toshimori K,Oura C

更新日期：1982-01-01 00:00:00

abstract：:Purinoceptor subtypes were localised to various tissue types present within the nasal cavity of the rat, using immunohistochemical methods. P2X3 receptor immunoreactivity was localised in the primary olfactory neurones located both in the olfactory epithelium and vomeronasal organs (VNO) and also on subepithelial nerv...

journal_title：Cell and tissue research

authors： Gayle S,Burnstock G

更新日期：2005-01-01 00:00:00

abstract：:Electron microscopy of the rat lymph node disclosed reticular cells in close association with bundles of collagenous fibrils 30-45 nm in diameter, and electron lucent "amorphous" substances surrounded by microfibrils 11 nm in diameter, with junctional complexes. The amorphous substances, distinctly revealed by orcein ...

journal_title：Cell and tissue research

authors： Miyata K,Takaya K

更新日期：1981-01-01 00:00:00

abstract：:The general ultrastructure of the electrocyte, the basic unit of the electric organs of Electrophorus electricus, is analyzed. Presented herein are detailed observations of the syncytial surface, its fibrillar coat, invaginations of the plasma membrane and synaptic terminals. Using Thiéry's method glycogen granules we...

journal_title：Cell and tissue research

authors： Machado RD,de Souza W,Pereira GC,de Oliveira Castro G

更新日期：1976-11-10 00:00:00

abstract：:Normal articular cartilages from the weight-bearing areas of the femoral condyles of the knee joints of 11 patients (3-20 years old) and of 35 Schwarzkopf sheep (3 months to 2 years old) were studied using the electron microscope. The study has shown that the matrix of normal articular cartilage is not only composed o...

journal_title：Cell and tissue research

authors： Hesse I

更新日期：1987-06-01 00:00:00

abstract：:The influence of adrenalectomy and administration of hypertonic saline on the amount of vasopressin, oxytocin, and neurophysin contained in the median eminence and the neural lobe of rats was studied by means of the following methods: (i) morphometric and microphotometric analyses of aldehyde fuchsin-stained histologi...

journal_title：Cell and tissue research

authors： Bock R,Detzer K,Geiger A,Lang RE,Ostermann E,Sinner G

更新日期：1983-01-01 00:00:00

abstract：:PC12 pheochromocytoma cells treated with nerve growth factor (NGF) in combination with high concentrations of the activators of adenylate cyclase, forskolin or cholera toxin, become more neuron-like in size than cells treated with NGF or with activators of adenylate cyclase alone. Cells treated simultaneously with NGF...

journal_title：Cell and tissue research

authors： Tischler AS,Mobtaker H,Kwan PW,Jason WJ,DeLellis RA,Wolfe HJ

更新日期：1987-07-01 00:00:00

abstract：:The lymphatic organization and its relationship to the vascular system in the rat small intestine was studied by scanning electron microscopy of corrosion casts and freeze-fractured tissues, and by light microscopy of injected preparations. The villus possessed 3-10 or more central lacteals depending upon the villous ...

journal_title：Cell and tissue research

authors： Ohtani O

更新日期：1987-05-01 00:00:00

abstract：:Beta-defensin 103 (DEFB103) shares little homology with 8 other members of the bovine beta-defensin family and in other species DEFB103 protein has diverse functions, including antimicrobial activity, a chemoattractant for dendritic cells, enhancing epithelial wound repair and regulating hair colour. Expression of the...

journal_title：Cell and tissue research

authors： Mirabzadeh-Ardakani A,Solie J,Gonzalez-Cano P,Schmutz SM,Griebel PJ

更新日期：2016-02-01 00:00:00

abstract：:Examination of pituitaries from young and adult turtles representing four families, reveals that in addition to the abundant juxtaneural pars tuberalis (juxPT) found in this class of reptiles, there is generally a substantial amount of pars tuberalis (PT) tissue closely associated with the pars distalis (PD). The PT f...

journal_title：Cell and tissue research

authors： Pearson AK,Licht P

更新日期：1982-01-01 00:00:00

abstract：:Caprine preantral follicles within ovarian fragments were cryopreserved in the absence or presence of 0.5 M sucrose with or without 1 M dimethyl sulfoxide and/or 1 M ethylene glycol (EG). After being thawed, they were washed in minimum essential medium with or without 0.3 M sucrose. Histological analysis of follicle i...

journal_title：Cell and tissue research

authors： Santos RR,Tharasanit T,Figueiredo JR,van Haeften T,van den Hurk R

更新日期：2006-09-01 00:00:00

abstract：:The long nonmyelinated portion of the unipolar process of spinal ganglion cells resembles in many instances the perikaryon and is characterized by the following structural pecularities: 1. The surface membrane displays numerous invaginations and evaginations, which interdigitate with folds of the investing satellite c...

journal_title：Cell and tissue research

authors： Zenker W,Högl E

更新日期：1976-01-27 00:00:00