Strategies to overcome the barrier: use of nanoparticles as carriers and modulators of barrier properties.

abstract：:In an attempt to identify pancreatic islet cells emitting formaldehyde-induced fluorescence (FIF), the pancreatic islets of the domestic fowl were studied by combined fluorescence, ultrastructural, silver-impregnation and immunohistochemical methods in the same section or in consecutive semi-thin and ultra-thin sectio...

journal_title：Cell and tissue research

authors： Watanabe T,Chikazawa H,Yamada J

更新日期：1984-01-01 00:00:00

abstract：:Dexamethasone (Dex) regulates osteoblastic and adipocytic differentiation in mesenchymal progenitor cells through regulation of Wnt/β-catenin signaling. To elucidate the regulatory mechanisms underlying the effects of Dex, we examine the expression of Axin2, which is an intracellular inhibitor of Wnt/β-catenin signali...

journal_title：Cell and tissue research

authors： Naito M,Mikami Y,Takagi M,Takahashi T

更新日期：2013-12-01 00:00:00

abstract：:Loss of wild-type p53 activity is thought to be a major predictor of failure to respond to radiotherapy and chemotherapy in various human cancers. This assumption is largely based on some cell-death studies in p53-knockout mice and on correlations of p53 status assessed by immunochemistry or single-strand conformation...

journal_title：Cell and tissue research

authors： Weller M

更新日期：1998-06-01 00:00:00

abstract：:In several animal species, galanin occurs in pancreatic nerves and inhibits insulin secretion. However, the presence and action of galanin in the human pancreas have not been established. Therefore, we examined the presence and nature of human pancreatic galanin-like immunoreactive material (GLIR) and the effects of g...

journal_title：Cell and tissue research

authors： Ahrén B,Ar'Rajab A,Böttcher G,Sundler F,Dunning BE

更新日期：1991-05-01 00:00:00

abstract：:Corneal fibroblasts, major cellular components of the corneal stroma, are loosely arrayed between collagen lamellae. They play an important role in the metabolic and physiological homeostasis mechanisms by which the cornea is kept transparent. This paper deals with the demonstration of the gap junctions between the co...

journal_title：Cell and tissue research

authors： Ueda A,Nishida T,Otori T,Fujita H

更新日期：1987-08-01 00:00:00

abstract：:Hydroxyindole O-methyltransferase (HIOMT)-immunoreactive cells and melatonin synthesis were demonstrated in bovine epithalamus (including the pineal gland) with monoclonal antibodies and cRNA probes to HIOMT. The HIOMT-immunoreactive product was present in the cytoplasm of pinealocytes. All identifiable pinealocytes w...

journal_title：Cell and tissue research

authors： Sato T,Deguchi T,Ichikawa T,Fujieda H,Wake K

更新日期：1991-03-01 00:00:00

abstract：:Previous light-microscopic and ultra-immunohistochemical tracer studies revealed the existence of an independent local immune response of the simian oral mucosa. This local response is attributed to the presence of minor salivary gland (MSG) duct-related lymphoid tissue. Semithin sections from a total of 263 Epon-embe...

journal_title：Cell and tissue research

authors： Nair PN,Schroeder HE

更新日期：1985-01-01 00:00:00

abstract：:We have previously demonstrated that tooth size is determined by dental mesenchymal factors. Exogenous bone morphogenetic protein (BMP)4, Noggin, fibroblast growth factor (FGF)3 and FGF10 have no effect on tooth size, despite the expressions of Bmp2, Bmp4, Fgf3, Fgf10 and Lef1 in the dental mesenchyme. Among the wingl...

journal_title：Cell and tissue research

authors： Cai J,Mutoh N,Shin JO,Tani-Ishii N,Ohshima H,Cho SW,Jung HS

更新日期：2011-09-01 00:00:00

abstract：:Changes in the ultrastructure of the toad epidermis during the moulting cycle are described on the basis of 17 skin preparations fixed in consecutive phases of the cycle. Our previous light microscopical findings that morphological changes are mainly restricted to a short period prior to and after shedding are confirm...

journal_title：Cell and tissue research

authors： Budtz PE,Larsen LO

更新日期：1975-06-24 00:00:00

abstract：:Two types of mitochondria-rich cells were found in the interplatelet areas of the gills of the migrating river lamprey. Both cell types are thought to be responsible for ion-transport across the gills. In the fresh-run migrant the gills are dominated by large, flask-shaped cells which show some ultrastructural similar...

journal_title：Cell and tissue research

authors： Morris R,Pickering AD

更新日期：1976-10-06 00:00:00

abstract：:The organization of the neuropeptide Y (NPY)-immunoreactive system in the forebrain, pineal organ and retina of a biweekly spawning fish (Fundulus heteroclitus) was investigated. Immunoreactivity was encountered in neurons of the nucleus olfactoretinalis, in the large population of neurons in the floor of the telencep...

journal_title：Cell and tissue research

authors： Subhedar N,Cerdá J,Wallace RA

更新日期：1996-02-01 00:00:00

abstract：:Intercellular bridges have been detected in ovarian follicle cells of Drosophila melanogaster. These bridges occur widely between follicle cells of previtellogenic chambers, while, in vitellogenic chambers, they become restricted to the columnar follicle cells. Usually, only one bridge is detectable between adjacent f...

journal_title：Cell and tissue research

authors： Giorgi F

更新日期：1978-01-31 00:00:00

abstract：:Normal articular cartilages from the weight-bearing areas of the femoral condyles of the knee joints of 11 patients (3-20 years old) and of 35 Schwarzkopf sheep (3 months to 2 years old) were studied using the electron microscope. The study has shown that the matrix of normal articular cartilage is not only composed o...

journal_title：Cell and tissue research

authors： Hesse I

更新日期：1987-06-01 00:00:00

abstract：:To identify structures involved in the translocation of the synaptic vesicles towards the presynaptic membrane, an ultrastructural study has been undertaken by means of (1) the E-PTA stain and (2) the HMM-labeling procedure. Using serial sections of E-PTA stained nervous tissue, especially those made in transversal an...

journal_title：Cell and tissue research

authors： LeBeux YJ,Willemot J

更新日期：1975-06-27 00:00:00

abstract：:Glycosylation plays an essential role during development, in processes such as morphogen distribution, cell-to-cell communication, and extracellular matrix formation. Glycosylation is regulated during development in both a spatial and temporal manner. This study presents a detailed description of glycan distribution f...

journal_title：Cell and tissue research

authors： Yano H,Yamamoto-Hino M,Goto S

更新日期：2009-04-01 00:00:00

abstract：:Rab11, a small monomeric GTPase associated with recycling endosomes, is a key molecule in the regulation of vesicular trafficking and is involved in the development and differentiation of many Drosophila tissues through interaction with diverse signaling pathways. In this study, we report for the first time that Rab11...

journal_title：Cell and tissue research

authors： Choubey PK,Roy JK

更新日期：2017-02-01 00:00:00

abstract：:This study explores the molecular composition of the tight junction (TJ) in human term placenta from normal women and from patients with preeclampsia, a hypertensive disorder of pregnancy. Maternal endothelial dysfunction is a critical characteristic of preeclampsia; hence, we have analyzed its impact on placental ves...

journal_title：Cell and tissue research

authors： Liévano S,Alarcón L,Chávez-Munguía B,González-Mariscal L

更新日期：2006-06-01 00:00:00

abstract：:Neuroblastoma cells grown on substrates in culture develop long processes and assume the morphology of normal neurons as judged light microscopically. The development of synapses in the cultured tissue is studied by periodic electron microscopic examination of the areas of contact between cells. The initial explants a...

journal_title：Cell and tissue research

authors： Spoerri PE,Glees P,Dresp W

更新日期：1980-01-01 00:00:00

abstract：:Isotocinergic (IT) neurons show physiological and morphological characteristcs that are similar to those of the other preoptic neuroendocrine cells in the goldfish. Preoptic IT cells show resting membrane potentials of 20-55 mV, action potentials of up to 100 mV, and physiological evidence of axonal branching. Dye-mar...

journal_title：Cell and tissue research

authors： Reaves TA Jr,Hayward JN

更新日期：1979-10-02 00:00:00

abstract：:Right superior cervical sympathectomy was performed in one-day old rats. This operation had a small but definite effect on the postnatal development of the submandibular gland. The gland on the sympathectomized side weighed less and contained smaller amounts of DNA, RNA and protein than the contralateral intact gland....

journal_title：Cell and tissue research

authors： Srinivasan R,Chang WW

更新日期：1977-05-10 00:00:00

abstract：:Electron microscopy of the rat lymph node disclosed reticular cells in close association with bundles of collagenous fibrils 30-45 nm in diameter, and electron lucent "amorphous" substances surrounded by microfibrils 11 nm in diameter, with junctional complexes. The amorphous substances, distinctly revealed by orcein ...

journal_title：Cell and tissue research

authors： Miyata K,Takaya K

更新日期：1981-01-01 00:00:00

abstract：:The mole has a single pair of accessory sex organs with features of both the prostate and the seminal vesicle, for which the term prostate gland is not appropriate. Seasonal changes occuring in this gland were related to four periods: a) the quiescence period, b) the maturation period, c) the active period and d) the ...

journal_title：Cell and tissue research

authors： Aumüller G,Greenberg J

更新日期：1976-12-10 00:00:00

abstract：:Transcriptome profiling of the pineal gland has revealed night/day differences in the expression of a major fraction of the genes active in this tissue, with two-thirds of these being nocturnal increases. A set of over 600 transcripts exhibit two-fold to >100-fold daily differences in abundance. These changes appear t...

journal_title：Cell and tissue research

authors： Bustos DM,Bailey MJ,Sugden D,Carter DA,Rath MF,Møller M,Coon SL,Weller JL,Klein DC

更新日期：2011-04-01 00:00:00

abstract：:Regenerated adrenocortical nodules were obtained by implanting fragments of the capsular tissue of excised adrenal glands into the musculus gracilis of rats (Belloni et al. 1990). Five months after the operation, operated rats showed a normal basal blood level of corticosterone, but a very low concentration of circula...

journal_title：Cell and tissue research

authors： Belloni AS,Neri G,Andreis PG,Musajo FG,Boscaro M,Mazzocchi G,Nussdorfer GG

更新日期：1991-07-01 00:00:00

abstract：:Neuroblastoma is an embryonal malignancy that affects normal development of the adrenal medulla and paravertebral sympathetic ganglia in early childhood. Extensive studies have revealed the molecular characteristics of human neuroblastomas, including abnormalities at genome, epigenome and transcriptome levels. However...

journal_title：Cell and tissue research

authors： Tsubota S,Kadomatsu K

更新日期：2018-05-01 00:00:00

abstract：:Modifications of hepatocyte cell surface were determined after single i.v. injection to rats of Pb(NO(3))(2) (known to induce liver hyperplasia followed by apoptosis) or GdCl(3) (known to induce proliferation of parenchymal cells and Kupffer cell depletion) or administration of GdCl(3) 24 h before Pb(NO(3))(2) injecti...

journal_title：Cell and tissue research

authors： Pagliara P,Chionna A,Carlà EC,Caforio S,Dini L

更新日期：2003-04-01 00:00:00

abstract：:Chondrocytes were isolated enzymatically from rabbit ear cartilage, grown in vitro or as autotransplants for 1, 2 or 5 weeks and then examined by transmission electron microscopy. A confluent monolayer formed rapidly in vitro and the cells later grew in multiple overlapping layers, producing thick sheets of cartilagin...

journal_title：Cell and tissue research

authors： Thyberg J,Hinek A

更新日期：1977-05-31 00:00:00

abstract：:Sacciform cells containing an acidophilic, proteinaceous secretion, were identified in the epidermis of the brown trout and Arctic char. This cell type increased in number during the chronic stages of infestation by the ectoparasitic flagellate, Ichthyobodo sp., in immature brown trout, and decreased during sexual mat...

journal_title：Cell and tissue research

authors： Pickering AD,Fletcher JM

更新日期：1987-02-01 00:00:00

abstract：:The maternal-fetal interface undergoes dynamic changes that promote successful development of the embryo/fetal allograft during pregnancy. This immune privilege of the conceptus is mediated through local and systemic cellular responses. In species in which endometrial decidualization accompanies pregnancy, unique immu...

journal_title：Cell and tissue research

authors： Zhang J,Dunk C,Croy AB,Lye SJ

更新日期：2016-01-01 00:00:00

abstract：:The cellular response of non-neuronal elements of the pyramidal cell layer of the rat hippocampus, especially the area CA3, was observed electron microscopically following destruction of this formation by means of intraventricular administration of kainic acid (KA). The neuroglial cell types responding to the KA-induc...

journal_title：Cell and tissue research

authors： Murabe Y,Ibata Y,Sano Y

更新日期：1981-01-01 00:00:00