Effect of neonatal sympathectomy on the postnatal differentiation of the submandibular gland of the rat.

Abstract:

:Right superior cervical sympathectomy was performed in one-day old rats. This operation had a small but definite effect on the postnatal development of the submandibular gland. The gland on the sympathectomized side weighed less and contained smaller amounts of DNA, RNA and protein than the contralateral intact gland. The postnatal development of acinar cells and granular convoluted ductal cells was retarded in the sympathectomized gland. The acinar cells which differentiated after the ganglionectomy were smaller than those in the contralateral intact gland and were filled with secretory granules but devoid of basal basophilia. The rate of cellular proliferation in the sympathectomized gland was, however, similar to that intact gland at various ages studied.

journal_name

Cell Tissue Res

journal_title

Cell and tissue research

authors

Srinivasan R,Chang WW

doi

10.1007/BF00227032

subject

Has Abstract

pub_date

1977-05-10 00:00:00

pages

99-109

issue

1

eissn

0302-766X

issn

1432-0878

journal_volume

180

pub_type

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