Abstract:
:A 68-year-old man with a fever of unknown origin was admitted to our hospital. Bilateral auricularis and nasal root inflammation, with auricular perichondritis positive for anti-type II collagen (CII) antibody, led to a diagnosis of relapsing polychondritis (RP). Because the patient was refractory for high-dose glucocorticoid therapy, adalimumab was used. After the initiation of 40 mg of adalimumab, a rapid improvement of clinical manifestations, with a reduction in tumor necrosis factor-alpha (TNF-α) and interleukin 6 (IL-6), together with a titer of anti-CII antibody was observed.
journal_name
Mod Rheumatoljournal_title
Modern rheumatologyauthors
Nakamura H,Suzuki T,Nagaoka K,Yamasaki S,Tamai M,Hayashi T,Kawakami Adoi
10.1007/s10165-011-0453-4subject
Has Abstractpub_date
2011-12-01 00:00:00pages
665-8issue
6eissn
1439-7595issn
1439-7609journal_volume
21pub_type
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journal_title:Modern rheumatology
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journal_title:Modern rheumatology
pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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更新日期:2020-03-01 00:00:00
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更新日期:2021-01-01 00:00:00
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更新日期:2015-07-01 00:00:00
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更新日期:2009-01-01 00:00:00
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更新日期:2015-09-01 00:00:00
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