Near-infrared fluorescence imaging with indocyanine green-lactosomes in a mouse model of rheumatoid arthritis.

abstract：OBJECTIVES:This pilot multicenter exercise aimed to evaluate the inter-observer reproducibility of synovial power Doppler (PD) signals in rheumatoid arthritis (RA) patients and to determine the factors influencing the measurements. METHODS:Two representative RA patients were assessed by four independent experienced so...

journal_title：Modern rheumatology

authors： Ikeda K,Seto Y,Ohno S,Sakamoto F,Henmi M,Fukae J,Narita A,Nakagomi D,Nakajima H,Tanimura K,Koike T

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVE:We seek to evaluate the opinions of nurses and doctors in Japan regarding EULAR recommendations for nurses' roles in the management of chronic inflammatory arthritis. METHODS:This is a cross-sectional survey within Japan. We randomly selected nurses and doctors engaged in consultation of patients with rheuma...

journal_title：Modern rheumatology

authors： Fusama M,Nakahara H,van Eijk-Hustings Y,Oliver S,Takeuchi T

更新日期：2017-09-01 00:00:00

abstract：OBJECTIVES:We aimed to clarify the characteristics of heme oxygenase (HO)-1 expressing cells in the synovium from rheumatoid arthritis (RA) and osteoarthritis (OA), and to investigate the co-expression of HO-1 and IgG-Fc/HLA-DR complex. METHODS:The characteristics of HO-1 expressing cells in the synovium were investig...

journal_title：Modern rheumatology

authors： Yang S,Ohe R,Aung NY,Kato T,Kabasawa T,Utsunomiya A,Takakubo Y,Takagi M,Yamakawa M

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVES:To provide evidence for the revision of clinical practice guideline (CPG) for the management of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) by the Japan Research Committee for Intractable Vasculitis. METHODS:PubMed, CENTRAL, and the Japan Medical Abstracts Society were searched fo...

journal_title：Modern rheumatology

authors： Nagasaka K,Harigai M,Hagino N,Hara A,Horita T,Hayashi T,Itabashi M,Ito S,Katsumata Y,Kawashima S,Naniwa T,Sada KE,Nango E,Nakayama T,Tsutsumino M,Yamagata K,Homma S,Arimura Y

更新日期：2019-01-01 00:00:00

abstract：:Abstract We report a case of hypocalcemic myopathy confounded by polymyositis due to an elevated level of serum creatine kinase (CK). A 30-year-old man was referred to our hospital for the treatment of provisionally diagnosed polymyositis. His presentation with tetany, hyporeflexia, and general fatigue, in addition to...

journal_title：Modern rheumatology

authors： Hirata D,Nagashima T,Saito S,Okazaki H,Kano S,Minota S

更新日期：2002-06-01 00:00:00

abstract：OBJECTIVE:Intra-articular (IA) injection of hyaluronic acid (HA) has been shown to relieve osteoarthritis (OA)-related pain and improve joint structure within a 1-year period. We examined the mid-term (2-year) efficacy of IA-HA in Japanese subjects by using a large-scale population-based cohort of the Research on Osteo...

journal_title：Modern rheumatology

authors： Oka H,Akune T,Muraki S,Tanaka S,Kawaguchi H,Nakamura K,Yoshimura N

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVES:Modern three-component total ankle arthroplasty (TAA) has favorable clinical results and survival rates. However, radiographic deterioration and worsening of clinical symptoms may occur in patients with rheumatoid arthritis (RA) or non-inflammatory arthritis (NA). The associations between outcomes and clinic...

journal_title：Modern rheumatology

authors： Iwata T,Ito H,Furu M,Ishikawa M,Azukizawa M,Yoshitomi H,Fujii T,Akiyama H,Matsuda S

更新日期：2017-05-01 00:00:00

abstract：:Here, we report the case of a 69-year-old man with limited granulomatosis with polyangiitis (GPA; formerly Wegener's granulomatosis) who developed papillary thyroid cancer, adenocarcinoma of the stomach, and myelodysplastic syndrome following glucocorticoid treatment. This is the first report to present multiple malig...

journal_title：Modern rheumatology

authors： Cheon YH,Kim MG,Kim JE,Ha CY,Lee SI,Kim HO

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:The aim of the present study was to analyze the score of fatigue in a large cohort of Brazilian patients with SpA, comparing different disease patterns and its association with demographic and disease-specific variables. METHODS:A common protocol of investigation was prospectively applied to 1492 Brazilian ...

journal_title：Modern rheumatology

authors： Bianchi WA,Elias FR,Carneiro S,Bortoluzzo AB,Gonçalves CR,da Silva JA,Ximenes AC,Bértolo MB,Ribeiro SL,Keiserman M,Skare TL,Menin R,Azevedo VF,Vieira WP,Albuquerque EN,Bonfiglioli R,Campanholo C,Carvalho HM,Costa IP,

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVES:The objective of this study is to develop clinical practice guideline (CPG) for Sjögren's syndrome (SS) based on recently available clinical and therapeutic evidences. METHODS:The CPG committee for SS was organized by the Research Team for Autoimmune Diseases, Research Program for Intractable Disease of the...

journal_title：Modern rheumatology

authors： Sumida T,Azuma N,Moriyama M,Takahashi H,Asashima H,Honda F,Abe S,Ono Y,Hirota T,Hirata S,Tanaka Y,Shimizu T,Nakamura H,Kawakami A,Sano H,Ogawa Y,Tsubota K,Ryo K,Saito I,Tanaka A,Nakamura S,Takamura E,Tanaka M

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVES:To determine whether ultrasonography (US) predicts Boolean remission in rheumatoid arthritis (RA) patients who had achieved disease activity score in 28 joints (DAS28)-based remission criteria. METHODS:Thirty-one RA patients in DAS28-based clinical remission were recruited. US semiquantitatively determined ...

journal_title：Modern rheumatology

authors： Yoshimi R,Hama M,Minegishi K,Kishimoto D,Watanabe T,Kamiyama R,Kirino Y,Asami Y,Ihata A,Tsunoda S,Ueda A,Takeno M,Ishigatsubo Y

更新日期：2014-07-01 00:00:00

abstract：:Bucillamine (Buc) is a disease-modifying antirheumatic drug (DMARD) developed in Japan, which has been used as one of the first-line DMARDs for the treatment of rheumatoid arthritis (RA) in Japan. However, direct comparison of this drug with standard DMARDs including sulfasalazine (SASP) and methotrexate (MTX) has bee...

journal_title：Modern rheumatology

authors： Iwatani M,Inoue E,Nakamura T,Nakajima A,Hara M,Tomatsu T,Kamatani N,Yamanaka H

更新日期：2006-01-01 00:00:00

abstract：:Abstract This work was undertaken to determine baseline urate metabolism in patients during the intermittent phase of gouty arthritis in order to decide on the best treatment for hyperuricemia. Parameters affecting serum urate levels, including uric acid clearance and urinary urate excretion, were re-evaluated in 30 p...

journal_title：Modern rheumatology

authors： Tsutani H,Kiriba C,Imamura S,Yoshio N,Nakamura T,Ueda T

更新日期：2000-12-01 00:00:00

abstract：:Aortitis, inflammation of the aortic tissue, is most commonly caused by vasculitic rheumatic conditions, and less frequently infectious organisms. Involvement of the aorta is well defined in HLA-B27-associated spondyloarthropathies such as long-standing ankylosing spondylitis and Reiter's syndrome. However, unlike oth...

journal_title：Modern rheumatology

authors： Tufan A,Engin Tezcan M,Kaya A,Mercan R,Oner Y,Ozturk MA

更新日期：2012-09-01 00:00:00

abstract：:IgG4-related disease (IgG4-RD) is a fascinating clinical entity first reported in this century in Japan, and includes a wide variety of diseases, such as formerly named Mikulicz's disease (MD), autoimmune pancreatitis (AIP), interstitial nephritis, prostatitis and retroperitoneal fibrosis. The Japanese IgG4 team organ...

journal_title：Modern rheumatology

authors： Umehara H,Okazaki K,Kawa S,Takahashi H,Goto H,Matsui S,Ishizaka N,Akamizu T,Sato Y,Kawano M,Research Program for Intractable Disease by the Ministry of Health, Labor and Welfare (MHLW) Japan.

更新日期：2021-01-28 00:00:00

abstract：:Abstract Little is known about the specific effects of the ultra-high molecular weight polyethylene (UHMWP) debris that is obtained from human interface membranes after revision for a failed total hip arthroplasty. This paper reports the effects of retrieved polyethylene particles on human monocyte/macrophages (M/M). ...

journal_title：Modern rheumatology

authors： Chiba J,Inoue K

更新日期：2000-03-01 00:00:00

abstract：:Abstract Methotrexate (MTX) is the most commonly used disease-modifying antirheumatic drug (DMARD) throughout the world. In Japan, MTX is recommended by the Japanese Ministry of Health, Labour, and Welfare to be given as the second or third DMARD and at a dosage of no more than 8 mg/week. We analyzed the efficacy of M...

journal_title：Modern rheumatology

authors： Kameda H,Amano K,Sekiguchi N,Takei H,Ogawa H,Nagasawa H,Takeuchi T

更新日期：2004-12-01 00:00:00

abstract：:Despite a number of published reports, including from our own laboratory, suggesting that adeno-associated virus (AAV) transduces mouse synovium, a careful analysis demonstrated transduction predominantly of the subsynovial muscle tissue, while the synovial lining is poorly transduced. To investigate the potential of ...

journal_title：Modern rheumatology

authors： Katakura S,Jennings K,Watanabe S,Adachi E,Thornton S,Gao GP,Wilson JM,Burstein H,Trapnell B,Hirsch R

更新日期：2004-01-01 00:00:00

abstract：:We report the case of a 73-year-old man with myelodysplastic syndrome (MDS) who developed Weber-Christian disease (WCD). Bone marrow aspirates showed refractory anemia with abnormal karyotypes such as trisomy 8, trisomy 8 and 14, and trisomy 8, 9, and 14. The patient had intermittent fever associated with multiple ten...

journal_title：Modern rheumatology

authors： Hojo N,Hasegawa H,Iwamasa K,Hojo S,Fujita S

更新日期：2004-01-01 00:00:00

abstract：:The expression of CD25 or CD28 on T cells was examined in patients with rheumatic diseases associated with interstitial pneumonitis (IP), in order to investigate the conditions of CD4+CD25+ regulatory T cells and CD8+CD28- suppressor T cells. Fifty-five patients with various rheumatic diseases and 23 normal controls w...

journal_title：Modern rheumatology

authors： Katagiri A,Morimoto S,Nakiri Y,Nakano S,Mitsuo A,Suzuki J,Amano H,Nozawa K,Asano M,Tokano Y,Hashimoto H,Takasaki Y

更新日期：2008-01-01 00:00:00

abstract：: ...

journal_title：Modern rheumatology

authors： Kajihara I,Jinnin M,Yamada S,Ichihara A,Makino T,Igata T,Masuguchi S,Fukushima S,Ihn H

更新日期：2013-04-04 00:00:00

abstract：:Objectives: To assess the middle-term outcome of iguratimod (IGU) in rheumatoid arthritis (RA) patients. Methods: Sixty-nine RA patients (14 males and 55 females, mean age of 64.0 years) receiving IGU-containing therapies were enrolled. We divided these patients into three groups based on the treatment at the baseline...

journal_title：Modern rheumatology

authors： Suto T,Yonemoto Y,Okamura K,Sakane H,Takeuchi K,Tamura Y,Kaneko T,Ayabe K,Chikuda H

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVES:The purpose of the present study was to describe our experience with the recombinant Fab' antibody fragment against TNF-α Certolizumab Pegol (CZP) in patients with Behçet's disease (BD) refractory to standardized therapies and previous biologic agents. METHODS:Retrieved data including demographic characteri...

journal_title：Modern rheumatology

authors： Lopalco G,Emmi G,Gentileschi S,Guerriero S,Vitale A,Silvestri E,Becatti M,Cavallo I,Fabiani C,Frediani B,Iannone F,Cantarini L

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:Neutrophil extracellular traps (NETs) are peculiar structures composed of the externalized chromatin with intracellular proteins and formed by activated neutrophils in a reactive oxygen species (ROS)-dependent manner. Aberrant NETs are considered to be autoantigens for anti-neutrophil cytoplasmic antibodies (...

journal_title：Modern rheumatology

authors： Kimura H,Matsuyama Y,Araki S,Koizumi A,Kariya Y,Takasuga S,Eguchi S,Nakanishi H,Sasaki J,Sasaki T

更新日期：2018-05-01 00:00:00

abstract：:Abstract Five cases of flexor tendon rupture in surgically treated rheumatoid wrists were studied. The tendon ruptures occurred in the thumb and index finger, and the ruptures site was in the carpal tunnel in all five cases. The main cause of rupture was the formation of bony irregularities in the form of bony spurs i...

journal_title：Modern rheumatology

authors： Kobayashi A,Futami T,Tsukamoto Y

更新日期：2001-06-01 00:00:00

abstract：:Cutaneous polyarteritis nodosa (cutaneous PAN) is a form of necrotizing vasculitis of small- and medium-sized arteries, primarily involving the skin. In juvenile cases, cutaneous PAN is known to be frequently associated with Group A β-hemolytic Streptococcus (GAS) infections. We herein describe the first reported juve...

journal_title：Modern rheumatology

authors： Yamamoto T,Inoue Y,Tomiita M,Oikawa M,Kambe N,Arima T,Shimojo N,Kohno Y

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVES:To assess the efficacy and safety of intravenous (IV) belimumab plus standard systemic lupus erythematosus (SLE) therapy standard of care (SoC) in Japanese patients with SLE. METHODS:A Phase 3, multicenter, double-blind, placebo-controlled, 52-week study (BEL 113750; NCT01345253) in patients with SLE, rando...

journal_title：Modern rheumatology

authors： Tanaka Y,Bass D,Chu M,Egginton S,Ji B,Struemper H,Roth D

更新日期：2019-05-01 00:00:00

abstract：:A 49-year-old Japanese woman treated with oral corticosteroids, methotrexate, and infliximab for malignant rheumatoid arthritis was admitted because of fever and low back pain. The white blood cell count and C-reactive protein concentration were elevated. Lumbar and pelvic computed tomography showed enlargement of the...

journal_title：Modern rheumatology

authors： Oda S,Fujinaga H,Takahashi K

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVES:Anti-cytokine therapy is reportedly useful in amyloid A (AA) amyloidosis complicating rheumatic diseases. However, to date no studies have directly compared the utility of tumour necrosis factor (TNF) inhibition to that of interleukin-6. The aim of our retrospective study was to compare the clinical utility ...

journal_title：Modern rheumatology

authors： Okuda Y,Ohnishi M,Matoba K,Jouyama K,Yamada A,Sawada N,Mokuda S,Murata Y,Takasugi K

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:The characteristics of lymphoproliferative disorders (LPD) in patients with rheumatoid arthritis (RA) remain unclear. Therefore, we retrospectively analyzed the clinical characteristics of these patients in our department. METHODS:Twenty RA patients who developed LPD between April 2003 and August 2016 in ou...

journal_title：Modern rheumatology

authors： Tsukui D,Kanda H,Shinozaki-Ushiku A,Tateishi S,Takeshima Y,Nagafuchi Y,Sasaki O,Iwasaki Y,Harada H,Shibuya M,Sumitomo S,Shoda H,Kubo K,Fujio K,Nakamura F,Kurokawa M,Fukayama M,Yamamoto K

更新日期：2018-07-01 00:00:00