Abstract:
OBJECTIVES:To provide evidence for the revision of clinical practice guideline (CPG) for the management of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) by the Japan Research Committee for Intractable Vasculitis. METHODS:PubMed, CENTRAL, and the Japan Medical Abstracts Society were searched for articles published between January 1994 and January 2015 to conduct systematic review (SR), and the quality of evidence was assessed with GRADE approach. RESULTS:Nine randomized controlled trials (RCTs) and two non-RCTs were adopted for remission induction therapy, three RCTs and two non-RCTs for plasma exchange, and five RCTs and one non-RCT for remission maintenance therapy. A significant difference was found in efficacy and safety for the following comparisons. In the non-RCT adopted for remission induction therapy, glucocorticoid (GC) + cyclophosphamide (CY) was significantly superior to GC monotherapy regarding remission. GC + intravenous CY for remission induction therapy was superior to GC + oral CY regarding death at one year, serious adverse events, and serious infection. Concomitant use of plasma exchange for remission induction therapy of AAV with severe renal dysfunction reduced risk of end-stage renal disease versus non-users at month 3. CONCLUSION:This SR provided necessary evidence for developing CPG for the management of ANCA-associated vasculitis.
journal_name
Mod Rheumatoljournal_title
Modern rheumatologyauthors
Nagasaka K,Harigai M,Hagino N,Hara A,Horita T,Hayashi T,Itabashi M,Ito S,Katsumata Y,Kawashima S,Naniwa T,Sada KE,Nango E,Nakayama T,Tsutsumino M,Yamagata K,Homma S,Arimura Ydoi
10.1080/14397595.2018.1500111subject
Has Abstractpub_date
2019-01-01 00:00:00pages
119-129issue
1eissn
1439-7595issn
1439-7609journal_volume
29pub_type
杂志文章,meta分析abstract:OBJECTIVES:Lupus enteritis (LE) is a rare but well-known gastrointestinal manifestation of systemic lupus erythematosus (SLE). This study was conducted to identify prognostic factors associated with poor responses in patients with LE. METHODS:We consecutively registered patients diagnosed with LE between January 2009 ...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1080/14397595.2020.1812871
更新日期:2020-09-07 00:00:00
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journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1080/14397595.2020.1804668
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journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1007/s10165-012-0720-z
更新日期:2013-07-01 00:00:00
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journal_title:Modern rheumatology
pub_type: 杂志文章
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journal_title:Modern rheumatology
pub_type: 杂志文章,评审
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更新日期:2018-05-01 00:00:00
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journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1080/14397595.2020.1784556
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journal_title:Modern rheumatology
pub_type: 杂志文章
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更新日期:2015-05-01 00:00:00
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journal_title:Modern rheumatology
pub_type: 临床试验,杂志文章
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更新日期:2016-11-01 00:00:00
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journal_title:Modern rheumatology
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journal_title:Modern rheumatology
pub_type: 杂志文章
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更新日期:2017-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s10165-004-0277-6
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更新日期:2005-01-01 00:00:00
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pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2018-11-01 00:00:00
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pub_type: 杂志文章,meta分析
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pub_type: 杂志文章
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更新日期:2017-05-01 00:00:00
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pub_type: 杂志文章,评审
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journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1007/s10165-012-0818-3
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2013-07-01 00:00:00
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pub_type: 杂志文章
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更新日期:2008-01-01 00:00:00
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pub_type: 杂志文章
doi:10.3109/14397595.2015.1060668
更新日期:2016-01-01 00:00:00
abstract:: ...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1007/s10165-013-0884-1
更新日期:2013-04-27 00:00:00
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journal_title:Modern rheumatology
pub_type: 杂志文章
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更新日期:2017-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2012-02-01 00:00:00
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journal_title:Modern rheumatology
pub_type: 杂志文章
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更新日期:2017-07-01 00:00:00
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journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/14397595.2013.852840
更新日期:2014-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2015-05-01 00:00:00