Survey on attitudes regarding EULAR recommendations for the role of nurses involved in medical care of patients with chronic inflammatory arthritis in Japan.

abstract：:We evaluated the prevalence of Helicobacter pylori infection and the association of H. pylori infection and/or nonsteroidal anti-inflammatory drug (NSAID) use with upper gastrointestinal (UGI) ulcers in a cohort of Japanese patients with rheumatoid arthritis (RA). Using the clinical database of the cohort of RA patien...

journal_title：Modern rheumatology

authors： Tanaka E,Singh G,Saito A,Syouji A,Yamada T,Urano W,Nakajima A,Taniguchi A,Tomatsu T,Hara M,Saito T,Kamatani N,Yamanaka H

更新日期：2005-01-01 00:00:00

abstract：:Cyclosporin A (CsA) has various adverse effects including neurotoxicity. We report the case of a 49-year-old Japanese woman with dermatomyositis who showed CsA-induced cortical blindness. The patient demonstrated cortical blindness despite having a normal blood concentration of CsA. The risk factors of CsA-induced cor...

journal_title：Modern rheumatology

authors： Sawabe T,Imafuku S

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:To obtain safety and efficacy data on combination treatment with iguratimod and methotrexate (MTX) in an open-label extension study in patients with active rheumatoid arthritis (RA). METHODS:Following a 28-week, randomized, double-blind trial of adding iguratimod or placebo to stable MTX therapy, patients en...

journal_title：Modern rheumatology

authors： Hara M,Ishiguro N,Katayama K,Kondo M,Sumida T,Mimori T,Soen S,Nagai K,Yamaguchi T,Yamamoto K,Iguratimod-Clinical Study Group.

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVE:The aim of the present study was to investigate the efficacy of arthroscopic enlargement of unidirectional valvular slits for the treatment of popliteal cysts and to evaluate potential factors affecting the outcomes of our arthroscopic procedure. METHODS:Twenty-nine patients aged 43-77 years with popliteal c...

journal_title：Modern rheumatology

authors： Ohishi T,Takahashi M,Suzuki D,Fujita T,Yamamoto K,Ushirozako H,Banno T,Matsuyama Y

更新日期：2015-09-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease. Although hematological anomalies are commonly found in SLE, severe polymorphonuclear leukocyte depletion is rare. Most episodes of severe granulocytopenia in SLE patients tend to occur as part of drug toxicity-induced medullar hypoplasia,...

journal_title：Modern rheumatology

authors： Sakai T,Hatano Y,Abe I,Ishii K,Fujiwara S

更新日期：2013-11-01 00:00:00

abstract：:We investigated the clinical efficacy and safety of tocilizumab (a humanized anti-IL-6 receptor antibody) monotherapy in active rheumatoid arthritis (RA) patients with an inadequate response to low dose methotrexate (MTX). In a multicenter, double-blind, randomized, controlled trial, 125 patients were allocated to rec...

journal_title：Modern rheumatology

authors： Nishimoto N,Miyasaka N,Yamamoto K,Kawai S,Takeuchi T,Azuma J,Kishimoto T

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:We aimed to analyze clinical features and treatment outcomes of otitis media caused by antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), i.e. otitis media with AAV (OMAAV). METHODS:This survey was performed between December 2013 and February 2014. The study began with a preliminary surv...

journal_title：Modern rheumatology

authors： Harabuchi Y,Kishibe K,Tateyama K,Morita Y,Yoshida N,Kunimoto Y,Matsui T,Sakaguchi H,Okada M,Watanabe T,Inagaki A,Kobayashi S,Iino Y,Murakami S,Takahashi H,Tono T

更新日期：2017-01-01 00:00:00

abstract：:We report a 24-year-old male with systemic lupus erythematosus (SLE) who developed influenza virus B-associated hemophagocytic syndrome and cardiac tamponade. Although the patient's general condition improved after steroid pulse therapy and pericardiocentesis, pericardial effusion re-accumulated. Colchicine and aspiri...

journal_title：Modern rheumatology

authors： Horai Y,Miyamura T,Takahama S,Sonomoto K,Nakamura M,Ando H,Minami R,Yamamoto M,Suematsu E

更新日期：2010-04-01 00:00:00

abstract：:We investigated the association between cigarette smoking and the risk of developing rheumatoid arthritis (RA) in the Malaysian population. A total of 1,056 RA patients and 1,416 matched controls aged 18-70 years within a defined area of Peninsular Malaysia were evaluated in a case-control study between August 2005 an...

journal_title：Modern rheumatology

authors： Yahya A,Bengtsson C,Lai TC,Larsson PT,Mustafa AN,Abdullah NA,Muhamad N,Hussein H,Klareskog L,Alfredsson L,Murad S

更新日期：2012-08-01 00:00:00

abstract：:Anti-tumor necrosis factor (anti-TNF) biologics are effective in the treatment of rheumatoid arthritis (RA); however, it is still not clear whether this treatment promotes the development of malignancies such as lymphoma. Human T-lymphotropic virus type 1 (HTLV-1), which is a causative agent of adult T-cell lymphoma (...

journal_title：Modern rheumatology

authors： Umekita K,Umeki K,Miyauchi S,Ueno S,Kubo K,Kusumoto N,Takajo I,Nagatomo Y,Okayama A

更新日期：2015-09-01 00:00:00

abstract：:A postoperative lung cancer patient presented with lymphadenopathy, pleural thickening, and 18F-fluorodeoxyglucose (FDG) uptake on a positron emission tomography-computed tomography (PET-CT) scan. Lung cancer recurrence was initially suspected, but bilateral submandibular masses with 18F-FDG uptake indicated the possi...

journal_title：Modern rheumatology

authors： Nakazawa S,Shimizu K,Nakano T,Kakegawa S,Atsumi J,Kamiyoshihara M,Hirato J,Takeyoshi I

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVES:The objective of this study is to develop clinical practice guideline (CPG) for Sjögren's syndrome (SS) based on recently available clinical and therapeutic evidences. METHODS:The CPG committee for SS was organized by the Research Team for Autoimmune Diseases, Research Program for Intractable Disease of the...

journal_title：Modern rheumatology

authors： Sumida T,Azuma N,Moriyama M,Takahashi H,Asashima H,Honda F,Abe S,Ono Y,Hirota T,Hirata S,Tanaka Y,Shimizu T,Nakamura H,Kawakami A,Sano H,Ogawa Y,Tsubota K,Ryo K,Saito I,Tanaka A,Nakamura S,Takamura E,Tanaka M

更新日期：2018-05-01 00:00:00

abstract：:Cutaneous polyarteritis nodosa (cutaneous PAN) is a form of necrotizing vasculitis of small- and medium-sized arteries, primarily involving the skin. In juvenile cases, cutaneous PAN is known to be frequently associated with Group A β-hemolytic Streptococcus (GAS) infections. We herein describe the first reported juve...

journal_title：Modern rheumatology

authors： Yamamoto T,Inoue Y,Tomiita M,Oikawa M,Kambe N,Arima T,Shimojo N,Kohno Y

更新日期：2015-01-01 00:00:00

abstract：:Abstract Sensitivity and specificity were compared among the American College of Rheumatology (ACR) 1987 classification criteria, the Yamasaki diagnostic criteria, and the Japan Rheumatism Association (JRA) diagnostic criteria for early rheumatoid arthritis (RA). The study included 90 patients who consulted our depart...

journal_title：Modern rheumatology

authors： Yamamoto N,Hagino H,Teshima R

更新日期：2000-09-01 00:00:00

abstract：:Abstract Methotrexate (MTX) is the most commonly used disease-modifying antirheumatic drug (DMARD) throughout the world. In Japan, MTX is recommended by the Japanese Ministry of Health, Labour, and Welfare to be given as the second or third DMARD and at a dosage of no more than 8 mg/week. We analyzed the efficacy of M...

journal_title：Modern rheumatology

authors： Kameda H,Amano K,Sekiguchi N,Takei H,Ogawa H,Nagasawa H,Takeuchi T

更新日期：2004-12-01 00:00:00

abstract：:Bucillamine (Bc) is a cysteine derivative with two SH groups, and a homolog of D-penicillamine, a disease-modifying antirheumatic drug (DMARD) widely used in Japan. However, it remains unclear whether Bc repairs bone erosion in patients with RA. Here, we treated three RA patients with Bc who subsequently showed radiog...

journal_title：Modern rheumatology

authors： Nanke Y,Iwatani M,Kobashigawa T,Yago T,Yamanaka H,Kotake S

更新日期：2009-01-01 00:00:00

abstract：:Tocilizumab (TCZ) is an interleukin-6 (IL-6) inhibitor used for the treatment of rheumatoid arthritis (RA). It was developed in 2008, and its effectiveness is supported by evidence from all over the world based on its first decade of use. Although the overall efficacy and safety profiles of TCZ are similar to those of...

journal_title：Modern rheumatology

authors： Ogata A,Kato Y,Higa S,Yoshizaki K

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to investigate the effect and potential mechanism of Cysteine-rich 61 (Cyr61) on stimulating MMP-3 expression by fibroblast-like synoviocytes (FLS) from rheumatoid arthritis (RA) patients. METHODS:Primarily cultured RA FLS were treated with exogenous Cyr61 protein or Cyr61-siRNA, t...

journal_title：Modern rheumatology

authors： Zhai T,Gao C,Huo R,Sheng H,Sun S,Xie J,He Y,Gao H,Li H,Zhang J,Li H,Sun Y,Lin J,Shen B,Xiao L,Li N

更新日期：2017-05-01 00:00:00

abstract：:Aortitis, inflammation of the aortic tissue, is most commonly caused by vasculitic rheumatic conditions, and less frequently infectious organisms. Involvement of the aorta is well defined in HLA-B27-associated spondyloarthropathies such as long-standing ankylosing spondylitis and Reiter's syndrome. However, unlike oth...

journal_title：Modern rheumatology

authors： Tufan A,Engin Tezcan M,Kaya A,Mercan R,Oner Y,Ozturk MA

更新日期：2012-09-01 00:00:00

abstract：:Objective: We conducted a questionnaire survey within a standard clinical setting to clarify that picture superiority effect (PSE) could be obtained by musculoskeletal ultrasound (MSKUS) examination.Methods: One hundred patients with rheumatoid arthritis or arthralgia, who visited the Rheumatology Unit, Department of ...

journal_title：Modern rheumatology

authors： Matsuki-Muramoto Y,Ogasawara M,Kawamoto T,Yamaji K,Tamura N

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:Anticentromere antibody (ACA) is generally considered to be a serological marker for systemic sclerosis (SSc). ACA-positive patients with primary Sjögren's syndrome (pSS) have also been reported. ACA often recognizes centromere proteins (CENPs): CENP-A, CENP-B, and CENP-C, and sometimes reacts to heterochrom...

journal_title：Modern rheumatology

authors： Tanaka N,Muro Y,Suzuki Y,Nishiyama S,Takada K,Sekiguchi M,Hashimoto N,Ohmura K,Shimoyama K,Saito I,Kawano M,Akiyama M

更新日期：2017-01-01 00:00:00

abstract：INTRODUCTION:We aimed to identify causes of false-positives in ultrasound scanning of synovial/tenosynovial/bursal inflammation and provide corresponding imaging examples. METHODS:We first performed systematic literature review to identify previously reported causes of false-positives. We next determined causes of fal...

journal_title：Modern rheumatology

authors： Ikeda K,Narita A,Ogasawara M,Ohno S,Kawahito Y,Kawakami A,Ito H,Matsushita I,Suzuki T,Misaki K,Ogura T,Kamishima T,Seto Y,Nakahara R,Kaneko A,Nakamura T,Henmi M,Fukae J,Nishida K,Sumida T,Koike T

更新日期：2016-01-01 00:00:00

abstract：:Bucillamine (Buc) is a disease-modifying antirheumatic drug (DMARD) developed in Japan, which has been used as one of the first-line DMARDs for the treatment of rheumatoid arthritis (RA) in Japan. However, direct comparison of this drug with standard DMARDs including sulfasalazine (SASP) and methotrexate (MTX) has bee...

journal_title：Modern rheumatology

authors： Iwatani M,Inoue E,Nakamura T,Nakajima A,Hara M,Tomatsu T,Kamatani N,Yamanaka H

更新日期：2006-01-01 00:00:00

abstract：:Tumor necrosis factor (TNF) plays an important role in the host defense mechanism, and anti-TNF antibody therapies may increase the risk of serious infections. We herein report a case of 57-year-old male with rheumatoid arthritis who developed brucellosis during treatment with infliximab in combination with methotrexa...

journal_title：Modern rheumatology

authors： Akgul O,Ozgocmen S

更新日期：2011-06-01 00:00:00

abstract：:To evaluate the efficacy of high-dose leukocytapheresis (LCAP) using a large filter in patients with refractory rheumatoid arthritis (RA), we conducted a multicenter, nonrandomized, open-label clinical study. Thirty patients with highly active RA were treated with high-dose LCAP performed 3-5 sessions at 1-week interv...

journal_title：Modern rheumatology

authors： Eguchi K,Saito K,Kondo M,Hidaka T,Ueki Y,Tanaka Y,LCAP Investigators in Kyushu College of Rheumatology (LIKCR).

更新日期：2007-01-01 00:00:00

abstract：INTRODUCTION:Fibromyalgia syndrome (FMS) is a chronic disease characterized by diffuse pain of unknown cause, fatigue, sleep disorders, cognitive dysfunction, and sensitivity. Fibromyalgia was shown to be associated with balance problems and increased incidence of falls. There are many theoretical mechanisms related to...

journal_title：Modern rheumatology

authors： Kasapoğlu Aksoy M,Altan L,Ökmen Metin B

更新日期：2017-09-01 00:00:00

abstract：:The patient described here is a 49-year-old woman who had hepatitis C virus (HCV) infection and rheumatoid arthritis (RA). Her RA had been successfully managed with methotrexate for about 10 years. After a sustained virological response was achieved with interferon therapy, treatment with adalimumab was instituted. Th...

journal_title：Modern rheumatology

authors： Noguchi O,Gibo Y

更新日期：2011-12-01 00:00:00

abstract：:Abstract Twenty-six patients with systemic lupus erythematosus (SLE) showing systemic lupus activity measure (SLAM) and SLE disease activity index (SLEDAI) scores ≤2, as well as a lower C4 concentration than the mean C4 levels of healthy controls, were selected to evaluate the C4 levels of SLE patients in remission. S...

journal_title：Modern rheumatology

authors： Yasuda M,Suenaga Y,Nishimukai H,Nobunaga M

更新日期：2002-09-01 00:00:00

abstract：OBJECTIVE:To evaluate the safety of peficitinib for the treatment of rheumatoid arthritis (RA) in Asian patients. METHODS:Safety data from one Phase 2b, two Phase 3, and one open-label long-term extension study [data cut-off 31 May 2018] were pooled into Phase 3 studies (peficitinib 100 and 150 mg/day, and placebo) an...

journal_title：Modern rheumatology

authors： Takeuchi T,Tanaka Y,Rokuda M,Izutsu H,Kaneko Y,Fukuda M,Kato D

更新日期：2020-11-09 00:00:00

abstract：OBJECTIVES:Several biological disease-modifying antirheumatic drugs (bDMARDs) are currently available for the treatment of rheumatoid arthritis (RA). Increasing evidence indicates that second-line bDMARDs are effective for inadequate responders to first-line bDMARDs. However, all previous studies investigated the use o...

journal_title：Modern rheumatology

authors： Matsuno H,Katayama K

更新日期：2017-03-01 00:00:00