Infliximab and brucellosis: not the usual suspects, this time.

abstract：:Abstract A woman with Sjögren's syndrome concurrently suffered bilateral fractures of the femoral neck without any proximate cause, while she had aseptic necrosis of the femoral head resulting from the treatment for Sjögren's syndrome. According to previous reports, fractures of the femoral neck following aseptic necr...

journal_title：Modern rheumatology

authors： Kamiya M,Ueno M,Yamaguchi H,Kanata S,Sohen S

更新日期：2004-12-01 00:00:00

abstract：:Nintedanib (Ofev™), an oral triple kinase inhibitor targeting pro-fibrotic pathways, has been used for treatment of idiopathic pulmonary fibrosis (IPF). Based on positive results from phase III, placebo-controlled, randomized comparative clinical trial conducted in patients with systemic sclerosis-associated interstit...

journal_title：Modern rheumatology

authors： Kuwana M,Azuma A

更新日期：2020-03-01 00:00:00

abstract：:Abstract This work was undertaken to evaluate clinical and immunological features in patients with systemic lupus erythematosus (SLE) complicated by Jaccoud's arthropathy. Patients diagnosed with SLE between 1985 and 1999, and who met the criteria of Villiaumey et al., were checked for Jaccoud's arthropathy. Clinical ...

journal_title：Modern rheumatology

authors： Takeishi M,Mimori A,Suzuki T

更新日期：2001-03-01 00:00:00

abstract：:Objectives: To evaluate the effectiveness of add-on iguratimod (IGU) in patients with rheumatoid arthritis (RA) who showed an inadequate response to tocilizumab (TCZ), especially patients who were intolerant of an effective dose of methotrexate (MTX). Methods: Thirty-one patients with RA (22 women, age 62.4 years, dis...

journal_title：Modern rheumatology

authors： Ebina K,Miyama A,Tsuboi H,Kaneshiro S,Nishikawa M,Owaki H,Tsuji S,Hirao M,Etani Y,Goshima A,Hashimoto J,Yoshikawa H

更新日期：2019-07-01 00:00:00

abstract：:Abstract Five cases of flexor tendon rupture in surgically treated rheumatoid wrists were studied. The tendon ruptures occurred in the thumb and index finger, and the ruptures site was in the carpal tunnel in all five cases. The main cause of rupture was the formation of bony irregularities in the form of bony spurs i...

journal_title：Modern rheumatology

authors： Kobayashi A,Futami T,Tsukamoto Y

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVES:The objective of this study is to clarify the surgical indication for rheumatoid forefoot deformity according to background characteristics and plantar pressure. METHODS:Patients with rheumatoid arthritis were divided into a non-surgical group (group N) and a surgical group (group S). The former consisted o...

journal_title：Modern rheumatology

authors： Lee H,Ishikawa H,Miyagawa Y,Takai C,Nomura Y,Nemoto T,Kobayashi D,Abe A,Otani H,Ito S,Nakazono K,Ishii T,Saito S,Tokuhashi Y,Murasawa A

更新日期：2017-11-01 00:00:00

abstract：:The influence of estrogen therapy on changes in arthritis and bone mineral density (BMD) was evaluated using an estrogen-replete collagen-induced arthritis (CIA) rat model. Seven-month-old female Sprague-Dawley rats (n = 30) were divided into the three groups; control (CONT), collagen sensitization (CIA), and CIA + 17...

journal_title：Modern rheumatology

authors： Yoshioka T,Hagino H,Yamasaki D,Okano T,Teshima R

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVES:To understand the status of mizoribine use in patients with lupus nephritis (LN) and to collect safety- and efficacy-related data on 2-year treatment with mizoribine. METHODS:A continuous survey was conducted between March 2010 and July 2015. RESULTS:The analysis set included 559 patients (mean age 39.5 ye...

journal_title：Modern rheumatology

authors： Takeuchi T,Okada K,Yoshida H,Yagi N

更新日期：2018-01-01 00:00:00

abstract：:Abstract A 56-year-old man presented with hyperproteinemia and renal dysfunction associated with antineutrophil cytoplasmic antibodies (ANCA). He had had a ventriculoperitoneal shunt tube made of silicone implanted 4 years earlier. In his renal biopsy, necrotizing crescentic glomerulonephritis was identified: tests fo...

journal_title：Modern rheumatology

authors： Bohgaki M,Mukai M,Notoya A,Kohno M,Takada A

更新日期：2003-03-01 00:00:00

abstract：:We report a case of a 60-year-old female with cutaneous polyarteritis nodosa (CPN) of the left ankle, accompanied by elevated serum interleukin (IL)-6 levels. Computed tomographic angiography revealed severe narrowing of medium-sized arteries in her left leg. Destructive arthropathy in the left ankle was identified by...

journal_title：Modern rheumatology

authors： Horai Y,Tokuyama A,Sumiyoshi R,Nakashima Y,Suzuki T,Okada A,Kawashiri SY,Ichinose K,Izumi Y,Miyashita T,Tamai M,Yamasaki S,Nakamura H,Hayashi T,Origuchi T,Kawakami A

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:Anticentromere antibody (ACA) is generally considered to be a serological marker for systemic sclerosis (SSc). ACA-positive patients with primary Sjögren's syndrome (pSS) have also been reported. ACA often recognizes centromere proteins (CENPs): CENP-A, CENP-B, and CENP-C, and sometimes reacts to heterochrom...

journal_title：Modern rheumatology

authors： Tanaka N,Muro Y,Suzuki Y,Nishiyama S,Takada K,Sekiguchi M,Hashimoto N,Ohmura K,Shimoyama K,Saito I,Kawano M,Akiyama M

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVE:To investigate which IgG subclasses contribute to the activation of the complement pathway in IgG4-related disease (IgG4RD) patients with hypocomplementemia. METHODS:Sera of IgG4RD patients were analyzed for the binding ability of IgG subclasses to complement component 1q (C1q). Polyethylene glycol (PEG) pre...

journal_title：Modern rheumatology

authors： Sugimoto M,Watanabe H,Asano T,Sato S,Takagi T,Kobayashi H,Ohira H

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVE:The aim of the present study was to investigate the efficacy of arthroscopic enlargement of unidirectional valvular slits for the treatment of popliteal cysts and to evaluate potential factors affecting the outcomes of our arthroscopic procedure. METHODS:Twenty-nine patients aged 43-77 years with popliteal c...

journal_title：Modern rheumatology

authors： Ohishi T,Takahashi M,Suzuki D,Fujita T,Yamamoto K,Ushirozako H,Banno T,Matsuyama Y

更新日期：2015-09-01 00:00:00

abstract：:The objective of this study was to show whether the disease activity of rheumatoid arthritis (RA) patients had improved in Japan, and whether the improvement of disease activity had resulted in a better outcome of patients. In a single-institute-based prospective observational cohort of RA patients (Institute of Rheum...

journal_title：Modern rheumatology

authors： Yamanaka H,Inoue E,Singh G,Tanaka E,Nakajima A,Taniguchi A,Hara M,Tomatsu T,Kamatani N

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVE:Intra-articular (IA) injection of hyaluronic acid (HA) has been shown to relieve osteoarthritis (OA)-related pain and improve joint structure within a 1-year period. We examined the mid-term (2-year) efficacy of IA-HA in Japanese subjects by using a large-scale population-based cohort of the Research on Osteo...

journal_title：Modern rheumatology

authors： Oka H,Akune T,Muraki S,Tanaka S,Kawaguchi H,Nakamura K,Yoshimura N

更新日期：2013-07-01 00:00:00

abstract：:Aortitis, inflammation of the aortic tissue, is most commonly caused by vasculitic rheumatic conditions, and less frequently infectious organisms. Involvement of the aorta is well defined in HLA-B27-associated spondyloarthropathies such as long-standing ankylosing spondylitis and Reiter's syndrome. However, unlike oth...

journal_title：Modern rheumatology

authors： Tufan A,Engin Tezcan M,Kaya A,Mercan R,Oner Y,Ozturk MA

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Efficacy of anti-tumor necrosis factor (anti-TNF)α treatment in patient with active ankylosing spondylitis (AS) had been proved by many clinical studies. Inflammation and new bone formation in spine were two pivotal aspects in AS. TNF α inhibitor could eliminate inflammation including clinical and laboratory...

journal_title：Modern rheumatology

authors： Zong HX,Xu SQ,Tong H,Wang XR,Pan MJ,Teng YZ

更新日期：2019-05-01 00:00:00

abstract：:We report a 24-year-old male with systemic lupus erythematosus (SLE) who developed influenza virus B-associated hemophagocytic syndrome and cardiac tamponade. Although the patient's general condition improved after steroid pulse therapy and pericardiocentesis, pericardial effusion re-accumulated. Colchicine and aspiri...

journal_title：Modern rheumatology

authors： Horai Y,Miyamura T,Takahama S,Sonomoto K,Nakamura M,Ando H,Minami R,Yamamoto M,Suematsu E

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVES:The purpose of the present study was to describe our experience with the recombinant Fab' antibody fragment against TNF-α Certolizumab Pegol (CZP) in patients with Behçet's disease (BD) refractory to standardized therapies and previous biologic agents. METHODS:Retrieved data including demographic characteri...

journal_title：Modern rheumatology

authors： Lopalco G,Emmi G,Gentileschi S,Guerriero S,Vitale A,Silvestri E,Becatti M,Cavallo I,Fabiani C,Frediani B,Iannone F,Cantarini L

更新日期：2017-11-01 00:00:00

abstract：:Idiopathic inflammatory myopathies (IIMs) are heterogeneous disorders that affect the skeletal muscles. Polymyositis, dermatomyositis, and inclusion body myositis are major IIM subsets. Immune-mediated necrotizing myopathy became recognized as a potentially new IIM subset. Since the new classification criteria publish...

journal_title：Modern rheumatology

authors： Sasaki H,Kohsaka H

更新日期：2018-11-01 00:00:00

abstract：:We report a case of acute generalized pustular bacterid (AGPB) concomitant with erythema nodosum (EN), polyarthritis, and Achilles tendinitis. The patient was admitted with a complaint of fever, widespread plural pustules, erythema, and polyarthralgia. Histopathological examination of the skin lesions demonstrated fea...

journal_title：Modern rheumatology

authors： Arita Y,Taguchi H,Hanada R,Tono T,Ohsone Y,Okata U,Irie R,Okano Y

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVE:To clarify polyarticular juvenile idiopathic arthritis (pJIA) patients who failed to maintain prolonged remission with the first biologic agent. METHODS:Fourteen pJIA patients were observed for 47.5 months (median) after initiating the first biologic agent. RESULTS:Eight maintained sustained clinical remiss...

journal_title：Modern rheumatology

authors： Kubota T,Imanaka H,Takei S,Yamatou T,Nerome Y,Yamasaki Y,Nonaka Y,Akaike H,Takezaki T,Kawano Y

更新日期：2016-01-01 00:00:00

abstract：:We report the case of a 73-year-old man with myelodysplastic syndrome (MDS) who developed Weber-Christian disease (WCD). Bone marrow aspirates showed refractory anemia with abnormal karyotypes such as trisomy 8, trisomy 8 and 14, and trisomy 8, 9, and 14. The patient had intermittent fever associated with multiple ten...

journal_title：Modern rheumatology

authors： Hojo N,Hasegawa H,Iwamasa K,Hojo S,Fujita S

更新日期：2004-01-01 00:00:00

abstract：:An 8-year-old girl with systemic-onset juvenile idiopathic arthritis (JIA) required surgical reduction for a dislocated left hip joint following failure of skin traction for 1 week. Unaided walking was achieved by 3 months postoperatively. Incongruence and irregularity of the hip joint remained but may resolve with ma...

journal_title：Modern rheumatology

authors： Inui K,Maeno T,Tada M,Takaoka K,Koike T

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:The aim of the present study was to analyze the score of fatigue in a large cohort of Brazilian patients with SpA, comparing different disease patterns and its association with demographic and disease-specific variables. METHODS:A common protocol of investigation was prospectively applied to 1492 Brazilian ...

journal_title：Modern rheumatology

authors： Bianchi WA,Elias FR,Carneiro S,Bortoluzzo AB,Gonçalves CR,da Silva JA,Ximenes AC,Bértolo MB,Ribeiro SL,Keiserman M,Skare TL,Menin R,Azevedo VF,Vieira WP,Albuquerque EN,Bonfiglioli R,Campanholo C,Carvalho HM,Costa IP,

更新日期：2014-11-01 00:00:00

abstract：:Research into the bone destruction associated with rheumatoid arthritis has highlighted the importance of the interplay of the immune and skeletal systems. Arthritic bone destruction is attributable to the defective control of osteoclastogenesis by T cells. We revealed that excessive expression of receptor activator o...

journal_title：Modern rheumatology

authors： Takayanagi H

更新日期：2005-01-01 00:00:00

abstract：:The involvement of valgus hindfoot deformity in hallux valgus deformity was confirmed in a rheumatoid arthritis case with a destructive valgus hindfoot deformity. Correction of severe valgus, calcaneal lateral offset, and pronated foot deformity instantly normalized hallux valgus deformities postoperatively. Thus, car...

journal_title：Modern rheumatology

authors： Yamada S,Hirao M,Tsuboi H,Akita S,Matsushita M,Ohshima S,Saeki Y,Hashimoto J

更新日期：2014-09-01 00:00:00

abstract：:Aseptic abscess (AA) is characterized by accumulation of neutrophils without evidence of infection, no response to antibiotics, and rapid response to corticosteroids. We report a case of multiple abscesses in the subcutaneous tissues and joints, and severe mitral valve regurgitation. Although AA did not respond to ant...

journal_title：Modern rheumatology

authors： Fukuda S,Nanki T,Morio T,Hasegawa H,Koike R,Miyasaka N

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVE:This study was performed to better know diagnosis associated with serum IgG4 concentration, and to explore the possibility for development of a serum IgG4 for IgG4-related disease (IgG4-RD) in Chinese populations. METHODS:We studied retrospectively 497 IgG4 serum subclass measurements from Peking Union Medic...

journal_title：Modern rheumatology

authors： Li P,Chen H,Deng C,Wu Z,Lin W,Zeng X,Zhang W,Zhang F,Li Y

更新日期：2016-07-01 00:00:00

abstract：:A 61-year-old woman was admitted for long-lasting fever and recurrent opportunistic infections during the treatment of SLE. She had been diagnosed as SLE and type-IV nephritis based on a renal biopsy and serological findings. A colonoscopy and liver biopsy revealed disseminated Mycobacterium avium complex infection. H...

journal_title：Modern rheumatology

authors： Ochi S,Kato S,Nakamura-Uchiyama F,Ohnishi K,Saito Y

更新日期：2017-05-01 00:00:00