Ultrasonography predicts achievement of Boolean remission after DAS28-based clinical remission of rheumatoid arthritis.

abstract：OBJECTIVE:Intra-articular (IA) injection of hyaluronic acid (HA) has been shown to relieve osteoarthritis (OA)-related pain and improve joint structure within a 1-year period. We examined the mid-term (2-year) efficacy of IA-HA in Japanese subjects by using a large-scale population-based cohort of the Research on Osteo...

journal_title：Modern rheumatology

authors： Oka H,Akune T,Muraki S,Tanaka S,Kawaguchi H,Nakamura K,Yoshimura N

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVES:The introduction of powerful antirheumatic drugs has dramatically improved the treatment of rheumatoid arthritis (RA), leading clinicians to reconsider the benefits of joint preservation for rheumatoid forefoot deformities. We have employed joint-preserving forefoot surgeries, including rotational closing-we...

journal_title：Modern rheumatology

authors： Yano K,Ikari K,Iwamoto T,Saito A,Naito Y,Kawakami K,Suzuki T,Imamura H,Sakuma Y,Hiroshima R,Momohara S

更新日期：2013-09-01 00:00:00

abstract：:The development of multiple large tophi in patients with gout is rare. We report magnetic resonance (MR) and histological features of large subcutaneous tophi in a 32-year-old male patient with no known arthritis. His subcutaneous lesions were confused with a neoplastic process, evaluated by MR imaging, and surgically...

journal_title：Modern rheumatology

authors： Ryu K,Takeshita H,Takubo Y,Hirata M,Taniguchi D,Masuzawa N,Kishimoto M,Kubo T

更新日期：2005-01-01 00:00:00

abstract：:Abstract A 17-year-old woman who was being treated with prednisolone for cutaneous vasculitis developed recurrent massive melena and abdominal pain. An emergency resection was performed because of uncontrollable melena, revealing many small intestinal ulcers with cytomegalic inclusion bodies, which were found by immun...

journal_title：Modern rheumatology

authors： Ota Y,Ohashi H,Otani C,Dei Y,Kondo S,Baba S

更新日期：2002-09-01 00:00:00

abstract：:Lower adiponectin levels in circulation are shown to be associated with endothelial dysfunction, which is a crucial feature in the evolution of atherosclerosis. The aim of our study is to evaluate the effect of anti-tumor necrosis factor (TNF) therapy on adiponectin levels with endothelial function and arterial stiffn...

journal_title：Modern rheumatology

authors： Komai N,Morita Y,Sakuta T,Kuwabara A,Kashihara N

更新日期：2007-01-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is a multisystem autoimmune connective-tissue disease with a complex phenotype and varying disease course. Although SLE often causes a polyarticular synovitis, there are only a few case reports of abnormalities of the synovial lined sacroiliac joints. We report a case with an overlap...

journal_title：Modern rheumatology

authors： Chandrasekhara PK,Jayachandran NV,Thomas J,Narsimulu G

更新日期：2009-01-01 00:00:00

abstract：:A 10-year cohort study was performed, involving all of the 118 patients treated with bucillamine in our hospital between 1988 and 1990. Evaluation was made on the basis of erythrocyte sedimentation rate, grip strength, joint score, duration of morning stiffness, and Lansbury index consisting of the above four paramete...

journal_title：Modern rheumatology

authors： Yokota N,Kuga Y,Kanazawa T,Morishita M,Tanida K,Itou K

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVES:To investigate CD44 levels in articular cartilage of knee osteoarthritis (OA) and the relationship between CD44 and severity of the disease. METHODS:All 50 cartilage tissues included normal and OA cartilage, and were ascribed to the following four groups on the basis of modified Mankin score: normal, mild l...

journal_title：Modern rheumatology

authors： Zhang FJ,Luo W,Gao SG,Su DZ,Li YS,Zeng C,Lei GH

更新日期：2013-11-01 00:00:00

abstract：:Objectives: Overactive bladder (OAB) is a clinical diagnosis defined with the presence of urinary urgency, usually accompanied by frequency and nocturia, with or without urgency urinary incontinence. Objective was to evaluate the demographic and clinical characteristics of Japanese systemic sclerosis (SSc) patients wi...

journal_title：Modern rheumatology

authors： Motegi SI,Sekiguchi A,Sekine Y,Nakayama H,Suzuki K,Ishikawa O

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVES:Joint space narrowing and osteophyte formation, radiographic features of knee osteoarthritis (OA), are not necessarily synchronous processes. We evaluated the relationship between medial minimum joint space width (mJSW) and osteophyte formation. METHODS:We conducted a retrospective study of 1050 individuals...

journal_title：Modern rheumatology

authors： Komatsu D,Hasegawa Y,Kojima T,Seki T,Higuchi Y,Ishiguro N

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVES:To assess the efficacy and safety of intravenous (IV) belimumab plus standard systemic lupus erythematosus (SLE) therapy standard of care (SoC) in Japanese patients with SLE. METHODS:A Phase 3, multicenter, double-blind, placebo-controlled, 52-week study (BEL 113750; NCT01345253) in patients with SLE, rando...

journal_title：Modern rheumatology

authors： Tanaka Y,Bass D,Chu M,Egginton S,Ji B,Struemper H,Roth D

更新日期：2019-05-01 00:00:00

abstract：:We conducted a comprehensive meta-analysis to quantitatively evaluate the association of cytokine gene polymorphisms with systemic sclerosis (SSc) susceptibility. Electronic databases were used to identify published studies before July 2011. In total, 23 case-control studies including 3524 SSc cases and 6086 healthy c...

journal_title：Modern rheumatology

authors： Peng WJ,Pan HF,Tao JH,Wang BX,Lu MM,Wang S,He Q,Wang J

更新日期：2012-09-01 00:00:00

abstract：:Abstract Five cases of flexor tendon rupture in surgically treated rheumatoid wrists were studied. The tendon ruptures occurred in the thumb and index finger, and the ruptures site was in the carpal tunnel in all five cases. The main cause of rupture was the formation of bony irregularities in the form of bony spurs i...

journal_title：Modern rheumatology

authors： Kobayashi A,Futami T,Tsukamoto Y

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVES:Locomotive syndrome (LS) encompasses conditions that may lead to the need for nursing services. We aimed to quantify the association between exercise habits during youth or the middle-age years and both physical function and the presence of LS in Japanese elderly people. METHODS:We examined 460 participants...

journal_title：Modern rheumatology

authors： Nishimura A,Ito N,Asanuma K,Akeda K,Ogura T,Sudo A

更新日期：2018-03-01 00:00:00

abstract：:A 61-year-old woman was admitted for long-lasting fever and recurrent opportunistic infections during the treatment of SLE. She had been diagnosed as SLE and type-IV nephritis based on a renal biopsy and serological findings. A colonoscopy and liver biopsy revealed disseminated Mycobacterium avium complex infection. H...

journal_title：Modern rheumatology

authors： Ochi S,Kato S,Nakamura-Uchiyama F,Ohnishi K,Saito Y

更新日期：2017-05-01 00:00:00

abstract：:One of the severe adverse effects of intra-articular injection in the knee is septic arthritis of the knee joint. Staphylococcus aureus is the most frequent pathogen of septic arthritis. Staphylococcal scalded skin syndrome (SSSS) refers to a spectrum of blistering skin diseases caused by S. aureus exfoliative toxins....

journal_title：Modern rheumatology

authors： Kunugiza Y,Tani M,Tomita T,Yoshikawa H

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVES:Systemic sclerosis (SSc) is an intractable connective tissue disease that causes skin and organ fibrosis. Interstitial lung disease (ILD) and pulmonary arterial hypertension (PAH) affect its prognosis. YKL-40 protein impacts inflammation and tissue remodeling. Therefore, we evaluated the utility of YKL-40 bl...

journal_title：Modern rheumatology

authors： Furukawa T,Matsui K,Kitano M,Yokoyama Y,Sekiguchi M,Azuma N,Imai Y,Hirota S,Yamanishi K,Sano H

更新日期：2019-05-01 00:00:00

abstract：:Abstract This work was undertaken to determine baseline urate metabolism in patients during the intermittent phase of gouty arthritis in order to decide on the best treatment for hyperuricemia. Parameters affecting serum urate levels, including uric acid clearance and urinary urate excretion, were re-evaluated in 30 p...

journal_title：Modern rheumatology

authors： Tsutani H,Kiriba C,Imamura S,Yoshio N,Nakamura T,Ueda T

更新日期：2000-12-01 00:00:00

abstract：OBJECTIVE:Neutrophil extracellular traps (NETs) are peculiar structures composed of the externalized chromatin with intracellular proteins and formed by activated neutrophils in a reactive oxygen species (ROS)-dependent manner. Aberrant NETs are considered to be autoantigens for anti-neutrophil cytoplasmic antibodies (...

journal_title：Modern rheumatology

authors： Kimura H,Matsuyama Y,Araki S,Koizumi A,Kariya Y,Takasuga S,Eguchi S,Nakanishi H,Sasaki J,Sasaki T

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVES:The present study aimed to conduct an epidemiological survey of Central Sensitization Inventory (CSI) scores in an older adult population and to investigate the association between the CSI scores, age, sex, pain intensity, site of pain, and health-related quality of life (QOL). METHODS:Participants were 373...

journal_title：Modern rheumatology

authors： Ide K,Yasuda T,Hasegawa T,Yamato Y,Yoshida G,Banno T,Arima H,Oe S,Mihara Y,Ushirozako H,Yamada T,Watanabe Y,Nakai K,Hoshino H,Matsuyama Y

更新日期：2020-10-02 00:00:00

abstract：:Abstract A 56-year-old man presented with hyperproteinemia and renal dysfunction associated with antineutrophil cytoplasmic antibodies (ANCA). He had had a ventriculoperitoneal shunt tube made of silicone implanted 4 years earlier. In his renal biopsy, necrotizing crescentic glomerulonephritis was identified: tests fo...

journal_title：Modern rheumatology

authors： Bohgaki M,Mukai M,Notoya A,Kohno M,Takada A

更新日期：2003-03-01 00:00:00

abstract：:Abstract Interstitial pneumonitis (IP) associated with polymyositis and dermatomyositis (PM/DM) is a serious complication that affects prognosis. We therefore undertook a retrospective multicenter study to examine the efficacy of a combination treatment with cyclosporin A (CsA) and corticosteroids. Fifty-three IP pati...

journal_title：Modern rheumatology

authors： Nagasaka K,Harigai M,Tateishi M,Hara M,Yoshizawa Y,Koike T,Miyasaka N

更新日期：2003-09-01 00:00:00

abstract：OBJECTIVES:The objective of this study is to evaluate the efficacy and safety of long-term (64 weeks; 52-week extension of a 12-week study) baricitinib treatment in Japanese patients with active rheumatoid arthritis (RA) despite methotrexate therapy. METHODS:Patients (N = 145) with active RA were randomized to placebo...

journal_title：Modern rheumatology

authors： Tanaka Y,Ishii T,Cai Z,Schlichting D,Rooney T,Macias W

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVES:The aim of our study is to clarify the association of myositis-specific autoantibodies (MSAs) with clinical and laboratory features in Japanese patients with juvenile idiopathic inflammatory myopathies (JIIMs). METHODS:We retrospectively analyzed the frequency of MSAs and their association with clinical or ...

journal_title：Modern rheumatology

authors： Ueki M,Kobayashi I,Takezaki S,Tozawa Y,Okura Y,Yamada M,Kuwana M,Ariga T

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVES:We investigated the characteristics of circulating T-helper (Th) cells and CD4+ regulatory T cells (Tregs) in polyarteritis nodosa (PAN). METHODS:Peripheral blood samples were obtained from 14 patients with PAN. Nine patients having granulomatosis with polyangiitis (GPA) and 11 healthy individuals (HC) were...

journal_title：Modern rheumatology

authors： Shimojima Y,Ishii W,Kishida D,Fukushima K,Ikeda SI

更新日期：2017-01-01 00:00:00

abstract：:A retrospective study was performed to investigate the clinical and radiological results of the Sauvé-Kapandji (S-K) procedure for the rheumatoid wrist. One hundred and eight rheumatoid wrists in 98 patients were operated on in our institute from 1992 to 2000, and in 82 wrists we used the S-K procedure. In other cases...

journal_title：Modern rheumatology

authors： Momohara S,Mamizuka K,Yonemoto K,Tomatsu T,Inoue K

更新日期：2004-01-01 00:00:00

abstract：:Anti-tumor necrosis factor (anti-TNF) biologics are effective in the treatment of rheumatoid arthritis (RA); however, it is still not clear whether this treatment promotes the development of malignancies such as lymphoma. Human T-lymphotropic virus type 1 (HTLV-1), which is a causative agent of adult T-cell lymphoma (...

journal_title：Modern rheumatology

authors： Umekita K,Umeki K,Miyauchi S,Ueno S,Kubo K,Kusumoto N,Takajo I,Nagatomo Y,Okayama A

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVES:To develop and evaluate an exercise program that the elderly could sustainably perform in the community or at home to recover from locomotive syndrome. METHODS:We produced 2 types of teaching media, video and pamphlet, describing 10 physical and mobility training exercises. The pilot study examined changes ...

journal_title：Modern rheumatology

authors： Hashizume H,Yoshimura N,Nagata K,Miyazaki N,Ishimoto Y,Nishiyama R,Oka H,Yamada H,Yoshida M

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:Increased femoral neck bone mineral density (BMD) in a hip with osteoarthritis (OA) has been previously reported, however, it is possible that increased BMD at sites other than the hip joint is influenced by the disease process of OA. Therefore, we measured BMD at locations different from the hip joint and de...

journal_title：Modern rheumatology

authors： Okano K,Ito M,Aoyagi K,Osaki M,Enomoto H,Yamaguchi K

更新日期：2014-03-01 00:00:00

abstract：:We report two cases of clinically amyopathic dermatomyositis (CADM) complicated by rapid progress interstitial lung disease (RPILD). The diagnosis of CADM was based on Gottron's papule and RPILD, and the absence of muscle weakness. The female patients were treated with early immunosuppressive therapies including stero...

journal_title：Modern rheumatology

authors： Horai Y,Isomoto E,Koga T,Okada A,Kawashiri SY,Tamai M,Yamasaki S,Nakamura H,Origuchi T,Hamaguchi Y,Fujimoto M,Kuwana M,Kawakami A

更新日期：2013-01-01 00:00:00