Systemic lupus erythematosus and dermatomyositis with symptomatic bilateral sacroiliitis: an unusual and interesting association.

abstract：OBJECTIVES:This study aimed to identify the prevalence of scoliosis and scoliosis-related factors of rheumatoid arthritis (RA). METHODS:In this study, 411 patients who underwent coronal total spine and lower limb radiography were enrolled. Patients with a Cobb angle ≥10° were diagnosed with scoliosis. Statistical anal...

journal_title：Modern rheumatology

authors： Mochizuki T,Yano K,Ikari K,Hiroshima R,Takaoka H,Kawakami K,Koenuma N,Ishibashi M,Shirahata T,Momohara S

更新日期：2016-01-01 00:00:00

abstract：:Aortitis, inflammation of the aortic tissue, is most commonly caused by vasculitic rheumatic conditions, and less frequently infectious organisms. Involvement of the aorta is well defined in HLA-B27-associated spondyloarthropathies such as long-standing ankylosing spondylitis and Reiter's syndrome. However, unlike oth...

journal_title：Modern rheumatology

authors： Tufan A,Engin Tezcan M,Kaya A,Mercan R,Oner Y,Ozturk MA

更新日期：2012-09-01 00:00:00

abstract：:The development of multiple large tophi in patients with gout is rare. We report magnetic resonance (MR) and histological features of large subcutaneous tophi in a 32-year-old male patient with no known arthritis. His subcutaneous lesions were confused with a neoplastic process, evaluated by MR imaging, and surgically...

journal_title：Modern rheumatology

authors： Ryu K,Takeshita H,Takubo Y,Hirata M,Taniguchi D,Masuzawa N,Kishimoto M,Kubo T

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVES:Joint space narrowing and osteophyte formation, radiographic features of knee osteoarthritis (OA), are not necessarily synchronous processes. We evaluated the relationship between medial minimum joint space width (mJSW) and osteophyte formation. METHODS:We conducted a retrospective study of 1050 individuals...

journal_title：Modern rheumatology

authors： Komatsu D,Hasegawa Y,Kojima T,Seki T,Higuchi Y,Ishiguro N

更新日期：2017-07-01 00:00:00

abstract：:IgG4-related disease (IgG4-RD) is a fascinating clinical entity first reported in this century in Japan, and includes a wide variety of diseases, such as formerly named Mikulicz's disease (MD), autoimmune pancreatitis (AIP), interstitial nephritis, prostatitis and retroperitoneal fibrosis. The Japanese IgG4 team organ...

journal_title：Modern rheumatology

authors： Umehara H,Okazaki K,Kawa S,Takahashi H,Goto H,Matsui S,Ishizaka N,Akamizu T,Sato Y,Kawano M,Research Program for Intractable Disease by the Ministry of Health, Labor and Welfare (MHLW) Japan.

更新日期：2021-01-28 00:00:00

abstract：OBJECTIVE:We seek to evaluate the opinions of nurses and doctors in Japan regarding EULAR recommendations for nurses' roles in the management of chronic inflammatory arthritis. METHODS:This is a cross-sectional survey within Japan. We randomly selected nurses and doctors engaged in consultation of patients with rheuma...

journal_title：Modern rheumatology

authors： Fusama M,Nakahara H,van Eijk-Hustings Y,Oliver S,Takeuchi T

更新日期：2017-09-01 00:00:00

abstract：:A postoperative lung cancer patient presented with lymphadenopathy, pleural thickening, and 18F-fluorodeoxyglucose (FDG) uptake on a positron emission tomography-computed tomography (PET-CT) scan. Lung cancer recurrence was initially suspected, but bilateral submandibular masses with 18F-FDG uptake indicated the possi...

journal_title：Modern rheumatology

authors： Nakazawa S,Shimizu K,Nakano T,Kakegawa S,Atsumi J,Kamiyoshihara M,Hirato J,Takeyoshi I

更新日期：2012-09-01 00:00:00

abstract：:Bucillamine (Buc) is a disease-modifying antirheumatic drug (DMARD) developed in Japan, which has been used as one of the first-line DMARDs for the treatment of rheumatoid arthritis (RA) in Japan. However, direct comparison of this drug with standard DMARDs including sulfasalazine (SASP) and methotrexate (MTX) has bee...

journal_title：Modern rheumatology

authors： Iwatani M,Inoue E,Nakamura T,Nakajima A,Hara M,Tomatsu T,Kamatani N,Yamanaka H

更新日期：2006-01-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune disease. Although hematological anomalies are commonly found in SLE, severe polymorphonuclear leukocyte depletion is rare. Most episodes of severe granulocytopenia in SLE patients tend to occur as part of drug toxicity-induced medullar hypoplasia,...

journal_title：Modern rheumatology

authors： Sakai T,Hatano Y,Abe I,Ishii K,Fujiwara S

更新日期：2013-11-01 00:00:00

abstract：:This report documents the results of a study performed to examine clinical use of mizoribine (MZR), using data from a large-scale prospective cohort study, IORRA (Institute of Rheumatology Rheumatoid Arthritis). The number of patients with RA entered in this study from October 2000 through October 2003 was 6238. Three...

journal_title：Modern rheumatology

authors： Tanaka E,Inoue E,Kawaguchi Y,Tomatsu T,Yamanaka H,Hara M,Kamatani N

更新日期：2006-01-01 00:00:00

abstract：:Pneumatosis cystoides intestinalis (PCI), which is characterized by the presence of multiple gas-filled mucosal, submucosal, or subserosal cysts located throughout the colon and/or small intestine, is an unusual complication of systemic lupus erythematosus (SLE). We report a case of a 33-year-old woman with a 5-year h...

journal_title：Modern rheumatology

authors： Yamaguchi Y,Ohno S,Yamazaki S,Ideguchi H,Shirai A,Takeno M,Ishigatsubo Y

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:We examined the prevalence and risk factors of vertebral fracture in female Japanese patients with systemic lupus erythematosus (SLE). METHODS:We performed lateral radiographs of the thoracic and lumbar spine and bone mineral density (BMD) measurements and collected demographic, lifestyle, clinical, and trea...

journal_title：Modern rheumatology

authors： Furukawa M,Kiyohara C,Horiuchi T,Tsukamoto H,Mitoma H,Kimoto Y,Uchino A,Nakagawa M,Oryoji K,Shimoda T,Harada M,Akashi K

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVES:The objective of this study is to evaluate the efficacy and safety of bortezomib for treating systemic lupus erythematosus (SLE), in patients whose disease activity could not be controlled. METHODS:Fourteen SLE patients with persistent disease activity were selected, who required prednisolone doses of >10 m...

journal_title：Modern rheumatology

authors： Ishii T,Tanaka Y,Kawakami A,Saito K,Ichinose K,Fujii H,Shirota Y,Shirai T,Fujita Y,Watanabe R,Chiu SW,Yamaguchi T,Harigae H

更新日期：2018-11-01 00:00:00

abstract：:Idiopathic inflammatory myopathies (IIMs) are heterogeneous disorders that affect the skeletal muscles. Polymyositis, dermatomyositis, and inclusion body myositis are major IIM subsets. Immune-mediated necrotizing myopathy became recognized as a potentially new IIM subset. Since the new classification criteria publish...

journal_title：Modern rheumatology

authors： Sasaki H,Kohsaka H

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVE:Increased femoral neck bone mineral density (BMD) in a hip with osteoarthritis (OA) has been previously reported, however, it is possible that increased BMD at sites other than the hip joint is influenced by the disease process of OA. Therefore, we measured BMD at locations different from the hip joint and de...

journal_title：Modern rheumatology

authors： Okano K,Ito M,Aoyagi K,Osaki M,Enomoto H,Yamaguchi K

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:To clarify the efficacy and safety of abatacept for secondary Sjögren's syndrome (SS) associated with rheumatoid arthritis (RA). METHODS:The primary endpoint of this open-labeled, prospective, observational multicenter study for secondary SS with RA was the remission rate of Simplified Disease Activity Index...

journal_title：Modern rheumatology

authors： Tsuboi H,Matsumoto I,Hagiwara S,Hirota T,Takahashi H,Ebe H,Yokosawa M,Yagishita M,Takahashi H,Kurata I,Ohyama A,Honda F,Asashima H,Miki H,Umeda N,Kondo Y,Hirata S,Saito K,Tanaka Y,Horai Y,Nakamura H,Kawakami A,

更新日期：2016-11-01 00:00:00

abstract：:OBJECTIVES: To validate the 2010 histopathological classification system of anti-neutrophil cytoplasmic antibodies (ANCA)-associated glomerulonephritis (GN) in a Japanese single-center cohort. METHODS: We retrospectively studied 54 patients (28 renally limited pauci-immune GN, 25 microscopic polyangiitis, and one Chur...

journal_title：Modern rheumatology

authors： Togashi M,Komatsuda A,Nara M,Omokawa A,Okuyama S,Sawada K,Wakui H

更新日期：2013-04-12 00:00:00

abstract：OBJECTIVE:To clarify polyarticular juvenile idiopathic arthritis (pJIA) patients who failed to maintain prolonged remission with the first biologic agent. METHODS:Fourteen pJIA patients were observed for 47.5 months (median) after initiating the first biologic agent. RESULTS:Eight maintained sustained clinical remiss...

journal_title：Modern rheumatology

authors： Kubota T,Imanaka H,Takei S,Yamatou T,Nerome Y,Yamasaki Y,Nonaka Y,Akaike H,Takezaki T,Kawano Y

更新日期：2016-01-01 00:00:00

abstract：:We report a case of a 60-year-old female with cutaneous polyarteritis nodosa (CPN) of the left ankle, accompanied by elevated serum interleukin (IL)-6 levels. Computed tomographic angiography revealed severe narrowing of medium-sized arteries in her left leg. Destructive arthropathy in the left ankle was identified by...

journal_title：Modern rheumatology

authors： Horai Y,Tokuyama A,Sumiyoshi R,Nakashima Y,Suzuki T,Okada A,Kawashiri SY,Ichinose K,Izumi Y,Miyashita T,Tamai M,Yamasaki S,Nakamura H,Hayashi T,Origuchi T,Kawakami A

更新日期：2014-01-01 00:00:00

abstract：:The most representative kidney lesion of IgG4-related disease (IgG4-RD) is plasma cell-rich tubulointerstitial nephritis (TIN) with distinctive imaging findings including multiple low-density lesions on contrast-enhanced computed tomography. In addition, membranous glomerulonephritis is a representative glomerular les...

journal_title：Modern rheumatology

authors： Kawano M,Saeki T,Nakashima H

更新日期：2019-03-01 00:00:00

abstract：:Abstract To determine the specificities of autoantibodies targeting cell cycle-associated antigens in rheumatic diseases, we studied 30 sera which were obtained from patients visiting our hospital and which exhibited a variegated speckled pattern in indirect immunofluorescence (IF). The immunoreactivities of the sera ...

journal_title：Modern rheumatology

authors： Fujinaga H,Takeuchi K,Kaneda K,Takasaki Y,Hashimoto H

更新日期：2001-09-01 00:00:00

abstract：OBJECTIVE:To assess the utilities of ultrasonography (US) and low-field magnetic resonance imaging (compacTscan, cMRI) in the diagnosis of subclinical synovitis of hand joints of patients with rheumatoid arthritis (RA). METHODS:A total of 1,540 joints of 77 RA patients were examined clinically, using US, using cMRI, a...

journal_title：Modern rheumatology

authors： Ogishima H,Tsuboi H,Umeda N,Horikoshi M,Kondo Y,Sugihara M,Suzuki T,Matsumoto I,Sumida T

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:To investigate and compare the risk for malignancy in rheumatoid arthritis (RA) patients treated with biologics in Japan to the general population. METHODS:Data for 14,440 patients from 335 institutions who were given infliximab, etanercept, adalimumab, golimumab, tocilizumab, or abatacept were retrieved fr...

journal_title：Modern rheumatology

authors： Harigai M,Nanki T,Koike R,Tanaka M,Watanabe-Imai K,Komano Y,Sakai R,Yamazaki H,Koike T,Miyasaka N

更新日期：2016-09-01 00:00:00

abstract：AIM:The purpose of this study was to assess morphological changes in the paravertebral muscles in patients with ankylosing spondylitis. MATERIALS AND METHODS:Fifty-one patients diagnosed with ankylosing spondylitis and a 50 member control group were included in the study. The surface area of the multifidus and erector...

journal_title：Modern rheumatology

authors： Resorlu H,Savas Y,Aylanc N,Gokmen F

更新日期：2017-07-01 00:00:00

abstract：:The association of either thrombotic thrombocytopenic purpura (TTP) or crescentic glomerulonephritis with Sjögren's syndrome is rare. We report a case of TTP appearing after the diagnosis of SjOgren's syndrome with crescentic glomerulonephritis and membranous nephropathy. Circulating immune complex was detected, and i...

journal_title：Modern rheumatology

authors： Abe H,Tsuboi N,Yukawa S,Tsuji S,Hayashi H,Yukawa N,Takanashi H,Tahara K,Tonozuka N,Hayashi T

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVES:The purpose of the present study was to describe our experience with the recombinant Fab' antibody fragment against TNF-α Certolizumab Pegol (CZP) in patients with Behçet's disease (BD) refractory to standardized therapies and previous biologic agents. METHODS:Retrieved data including demographic characteri...

journal_title：Modern rheumatology

authors： Lopalco G,Emmi G,Gentileschi S,Guerriero S,Vitale A,Silvestri E,Becatti M,Cavallo I,Fabiani C,Frediani B,Iannone F,Cantarini L

更新日期：2017-11-01 00:00:00

abstract：:The current study investigates the role of regulatory T (Treg) cells in the pathogenesis of ocular attack in patients with Behcet's disease (BD). Nineteen BD patients with ocular complications (BDo), including 11 BD patients with ocular attack (BDa) and eight BD patients with inactive ocular complications (BDi), were ...

journal_title：Modern rheumatology

authors： Nanke Y,Kotake S,Goto M,Ujihara H,Matsubara M,Kamatani N

更新日期：2008-01-01 00:00:00

abstract：:Risk of knee osteoarthritis (OA) was assessed in a population-based case-control study of Japanese men. The study covered three health districts in Wakayama and Osaka prefectures, Japan. Subjects were male individuals >or=45 years old diagnosed radiographically with knee OA, and who did not display any established cau...

journal_title：Modern rheumatology

authors： Yoshimura N,Kinoshita H,Hori N,Nishioka T,Ryujin M,Mantani Y,Miyake M,Takeshita T,Ichinose M,Yoshiida M,Oka H,Kawaguchi H,Nakamura K,Cooper C

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVES:The aims of this study were to clarify the long-term outcome of patients with polymyositis and dermatomyositis (PM/DM) and to elucidate prognostic factors using statistical analysis. METHODS:We enrolled patients with PM/DM who visited our department between 1990 and 2014. Diagnoses of PM/DM and clinically a...

journal_title：Modern rheumatology

authors： Ishizuka M,Watanabe R,Ishii T,Machiyama T,Akita K,Fujita Y,Shirota Y,Fujii H,Harigae H

更新日期：2016-01-01 00:00:00

abstract：:Relapsing polychondritis (RP) is a rare disease of unknown etiology causing systematic inflammation and resulting in destruction of cartilaginous tissues. We describe here an 18-year-old Japanese woman who developed severe airway stenosis as the initial symptom with auricular, nasal, and ocular inflammation. The effec...

journal_title：Modern rheumatology

authors： Yamaoka K,Saito K,Hanami K,Nakayamada S,Nawata M,Iwata S,Azuma T,Tanaka Y

更新日期：2007-01-01 00:00:00