Abstract:
AIM:The purpose of this study was to assess morphological changes in the paravertebral muscles in patients with ankylosing spondylitis. MATERIALS AND METHODS:Fifty-one patients diagnosed with ankylosing spondylitis and a 50 member control group were included in the study. The surface area of the multifidus and erector spinae muscles was measured at four levels between L1 and L5, and fatty degeneration in these muscles was scored. Lumbosacral and lumbar lordotic angles were determined for the patient and control groups. RESULTS:Loss of muscle cross-sectional area compatible with atrophy was present at all four levels in the paraspinal muscles in patients with ankylosing spondylitis. A negative correlation was observed between paravertebral muscle area and duration of disease at three levels, but not at L1-2. Although muscle area decreased with the duration of disease at the L1-2 level, this was not statistically significant (r= -0.195, p = 0.171). Comparison of intramuscular fatty degeneration between the groups revealed increased intramuscular fat at all levels in patients with ankylosing spondylitis, with the exception of L3-4, and a positive correlation between fatty degeneration and duration of disease was determined at all levels. CONCLUSION:Chronic inflammation, cytokine-mediated fibrosis, immobilization, and postural changes in ankylosing spondylitis contribute to fatty degeneration and atrophy in the paravertebral muscles.
journal_name
Mod Rheumatoljournal_title
Modern rheumatologyauthors
Resorlu H,Savas Y,Aylanc N,Gokmen Fdoi
10.1080/14397595.2016.1245176subject
Has Abstractpub_date
2017-07-01 00:00:00pages
683-687issue
4eissn
1439-7595issn
1439-7609journal_volume
27pub_type
杂志文章abstract::Abstract Five cases of flexor tendon rupture in surgically treated rheumatoid wrists were studied. The tendon ruptures occurred in the thumb and index finger, and the ruptures site was in the carpal tunnel in all five cases. The main cause of rupture was the formation of bony irregularities in the form of bony spurs i...
journal_title:Modern rheumatology
pub_type: 杂志文章
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journal_title:Modern rheumatology
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journal_title:Modern rheumatology
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journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/s101650070020
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journal_title:Modern rheumatology
pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Modern rheumatology
pub_type: 杂志文章
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pub_type: 杂志文章
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pub_type: 杂志文章,meta分析
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pub_type: 杂志文章,评审
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pub_type: 临床试验,杂志文章
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pub_type: 杂志文章
doi:10.1007/s10165-004-0359-5
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更新日期:2017-01-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2013-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s10165-013-0877-0
更新日期:2013-04-12 00:00:00
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更新日期:2011-10-01 00:00:00