Abstract:
:Synovial vascularization in the knee joints of six patients with rheumatoid arthritis who were treated with infliximab was evaluated by Doppler sonography. Power Doppler sonography demonstrated a significant reduction of color flow signals (P < 0.05), and spectral Doppler sonography demonstrated a significant increase in vascular resistance (P < 0.05) at week 6 (after three injections) evaluation of the therapy. A significant decrease in the number of tender joints (P < 0.05) and C-reactive protein value (P < 0.05) was also observed in these patients.
journal_name
Mod Rheumatoljournal_title
Modern rheumatologyauthors
Takahashi A,Sato A,Yamadera Y,Takeda I,Kanno T,Ohguchi Y,Nishimaki T,Kasukawa Rdoi
10.1007/s10165-004-0359-5subject
Has Abstractpub_date
2005-01-01 00:00:00pages
37-40issue
1eissn
1439-7595issn
1439-7609journal_volume
15pub_type
杂志文章abstract::Abstract We report a case of hypocalcemic myopathy confounded by polymyositis due to an elevated level of serum creatine kinase (CK). A 30-year-old man was referred to our hospital for the treatment of provisionally diagnosed polymyositis. His presentation with tetany, hyporeflexia, and general fatigue, in addition to...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/s101650200032
更新日期:2002-06-01 00:00:00
abstract:OBJECTIVES:A nationwide survey was conducted to assess the number of patients, clinical aspects, treatment, and prognosis of adult Still's disease (ASD) in Japan. METHODS:A primary questionnaire was sent to randomly selected medical institutions in order to estimate the number of patients. We sent a secondary question...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/14397595.2014.974881
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVE:To clarify the efficacy and safety of abatacept for secondary Sjögren's syndrome (SS) associated with rheumatoid arthritis (RA). METHODS:The primary endpoint of this open-labeled, prospective, observational multicenter study for secondary SS with RA was the remission rate of Simplified Disease Activity Index...
journal_title:Modern rheumatology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.3109/14397595.2016.1158773
更新日期:2016-11-01 00:00:00
abstract::Abstract To determine the specificities of autoantibodies targeting cell cycle-associated antigens in rheumatic diseases, we studied 30 sera which were obtained from patients visiting our hospital and which exhibited a variegated speckled pattern in indirect immunofluorescence (IF). The immunoreactivities of the sera ...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/s101650170008
更新日期:2001-09-01 00:00:00
abstract:OBJECTIVES:To evaluate joint inflammation using 3-T MRI in rheumatoid arthritis (RA) patients treated with conventional disease modifying anti-rheumatic drugs (cDMARDs) as compared to inhibitors for tumor necrosis factor α (TNFi) over 12 months. METHODS:Prospective epidemiologic clinical pilot study using the RA MRI s...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1080/14397595.2018.1467525
更新日期:2019-05-01 00:00:00
abstract:OBJECTIVES:The objective of this study is to evaluate the efficacy and safety of bortezomib for treating systemic lupus erythematosus (SLE), in patients whose disease activity could not be controlled. METHODS:Fourteen SLE patients with persistent disease activity were selected, who required prednisolone doses of >10 m...
journal_title:Modern rheumatology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1080/14397595.2018.1432331
更新日期:2018-11-01 00:00:00
abstract::An 8-year-old girl with systemic-onset juvenile idiopathic arthritis (JIA) required surgical reduction for a dislocated left hip joint following failure of skin traction for 1 week. Unaided walking was achieved by 3 months postoperatively. Incongruence and irregularity of the hip joint remained but may resolve with ma...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1007/s10165-004-0330-5
更新日期:2004-01-01 00:00:00
abstract::Abstract Osteoarthritis (OA) is considered to be a complex illness in which the tissues of the joint play a significant role in the initiation and/or progression of the pathophysiology. We still do not completely understand what initiates the degradation and loss of cartilage. However, it has been suggested that incr...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/s101650300001
更新日期:2003-03-01 00:00:00
abstract:OBJECTIVES:We aimed to clarify the characteristics of heme oxygenase (HO)-1 expressing cells in the synovium from rheumatoid arthritis (RA) and osteoarthritis (OA), and to investigate the co-expression of HO-1 and IgG-Fc/HLA-DR complex. METHODS:The characteristics of HO-1 expressing cells in the synovium were investig...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1080/14397595.2019.1704976
更新日期:2021-01-01 00:00:00
abstract::We report a patient with the extremely rare familial multiple lipomatosis syndrome, who developed the uncommon autoimmune disease cytophagic histiocytic panniculitis, manifested as inflammation of preexisting lipomas. Despite his initial critical condition and unsuccessful treatment with steroids, he responded to cycl...
journal_title:Modern rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10165-011-0487-7
更新日期:2012-02-01 00:00:00
abstract::We conducted a comprehensive meta-analysis to quantitatively evaluate the association of cytokine gene polymorphisms with systemic sclerosis (SSc) susceptibility. Electronic databases were used to identify published studies before July 2011. In total, 23 case-control studies including 3524 SSc cases and 6086 healthy c...
journal_title:Modern rheumatology
pub_type: 杂志文章,meta分析
doi:10.1007/s10165-011-0574-9
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVE:To evaluate total antioxidant capacity (TAC) and total oxidative stress (TOS) values in patients with myofascial pain syndrome (MPS). METHOD:The study comprised 38 patients diagnosed with MPS and 30 healthy volunteers. The age, body mass index (BMI) and pain scores (evaluation by visual analogue scales) of a...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/14397595.2014.886984
更新日期:2014-11-01 00:00:00
abstract:OBJECTIVES:To evaluate, through a systematic review of the literature, the association between the use of biological disease-modifying antirheumatic drugs (bDMARDs) and surgical site infection (SSI) or wound healing delay after orthopedic surgery in patients with rheumatoid arthritis (RA). METHODS:A systematic review ...
journal_title:Modern rheumatology
pub_type: 杂志文章,meta分析,评审
doi:10.3109/14397595.2015.1014302
更新日期:2015-09-01 00:00:00
abstract:OBJECTIVE:No available anti-osteoporotic medication has been shown to completely prevent declines in bone mineral density (BMD) and the resulting increased risk of fracture. The objective of this study was to investigate the risk factors for treatment failure in osteoporotic patients with rheumatoid arthritis (RA). ME...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/14397595.2015.1069444
更新日期:2016-01-01 00:00:00
abstract::Peripheral neuropathies should be recognized as the adverse effects of biological agents, especially anti-TNF agents. However, no solid clinical databases for biological agent-associated peripheral neuropathies (BAPN) have been established in Japan. Here we report two cases of peripheral neuropathy associated with ant...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/14397595.2013.859770
更新日期:2016-01-01 00:00:00
abstract::We present the case of a 60-year-old female patient with systemic sclerosis complicated by pulmonary hypertension. Ten days after the initiation of treatment with bosentan, high fever and skin eruptions were noted. In the previous reports, the frequency of drug-induced skin eruptions has not been well documented. Sinc...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1007/s10165-006-0477-3
更新日期:2006-01-01 00:00:00
abstract::A 20-year-old man presented with recurrent hemoptysis for seven months. A small subpleural nodule in his right lower lobe was found and excised surgically. Based on the presence of antiphospholipid antibodies (aPL) and vascular wall hypertrophy without vasculitis or an intraluminal thrombus, nonthrombotic proliferativ...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1080/14397595.2016.1218596
更新日期:2019-03-01 00:00:00
abstract::A 52-year-old woman with a 6-year history of systemic lupus erythematosus (SLE) developed acute abdominal pain, nausea, vomiting, and diarrhea accompanied by hypocomplementemia. Herpes simplex virus (HSV) esophagitis and lupus enteritis were diagnosed on the basis of the results of endoscopic and histological examinat...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1007/s10165-009-0237-2
更新日期:2010-02-01 00:00:00
abstract::A female rheumatoid arthritis patient was admitted for productive cough and general fatigue that had gradually developed after leflunomide therapy. Side effects including severe hypoxia, thrombocytopenia, lymphocytopenia, and macrocytic anemia with schistocytes (probably drug-induced megaloblastic anemia) were noted. ...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1007/s10165-007-0613-8
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVES:To provide evidence for the revision of clinical practice guideline (CPG) for the management of antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) by the Japan Research Committee for Intractable Vasculitis. METHODS:PubMed, CENTRAL, and the Japan Medical Abstracts Society were searched fo...
journal_title:Modern rheumatology
pub_type: 杂志文章,meta分析
doi:10.1080/14397595.2018.1500111
更新日期:2019-01-01 00:00:00
abstract::We report a patient who had a 4-year history of adult-onset Still's disease (AOSD) and showed a prominent increase in large granular lymphocytes (LGL) when she developed severe Pseudomonas conjunctivitis due to Pseudomonas aeruginosa, skin eruptions, liver damage, and abnormal findings in coagulation studies, without ...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1007/s10165-006-0462-x
更新日期:2006-01-01 00:00:00
abstract::Idiopathic inflammatory myopathies (IIMs) are heterogeneous disorders that affect the skeletal muscles. Polymyositis, dermatomyositis, and inclusion body myositis are major IIM subsets. Immune-mediated necrotizing myopathy became recognized as a potentially new IIM subset. Since the new classification criteria publish...
journal_title:Modern rheumatology
pub_type: 杂志文章,评审
doi:10.1080/14397595.2018.1467257
更新日期:2018-11-01 00:00:00
abstract:AIM:The purpose of this study was to assess morphological changes in the paravertebral muscles in patients with ankylosing spondylitis. MATERIALS AND METHODS:Fifty-one patients diagnosed with ankylosing spondylitis and a 50 member control group were included in the study. The surface area of the multifidus and erector...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1080/14397595.2016.1245176
更新日期:2017-07-01 00:00:00
abstract::Abstract Sensitivity and specificity were compared among the American College of Rheumatology (ACR) 1987 classification criteria, the Yamasaki diagnostic criteria, and the Japan Rheumatism Association (JRA) diagnostic criteria for early rheumatoid arthritis (RA). The study included 90 patients who consulted our depart...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/s101650070020
更新日期:2000-09-01 00:00:00
abstract:OBJECTIVE:Increased femoral neck bone mineral density (BMD) in a hip with osteoarthritis (OA) has been previously reported, however, it is possible that increased BMD at sites other than the hip joint is influenced by the disease process of OA. Therefore, we measured BMD at locations different from the hip joint and de...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/14397595.2013.854078
更新日期:2014-03-01 00:00:00
abstract::Objective: This study aimed to clarify whether plasma acrolein level actually increases in rheumatoid arthritis (RA) patients, and to elucidate whether any relationship exists between the levels and the RA background variables.Methods: Plasma levels of protein-conjugated acrolein (PC-Acro) in 84 patients (RA group) an...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1080/14397595.2020.1775921
更新日期:2020-06-16 00:00:00
abstract:OBJECTIVES:The aim of our study is to clarify the association of myositis-specific autoantibodies (MSAs) with clinical and laboratory features in Japanese patients with juvenile idiopathic inflammatory myopathies (JIIMs). METHODS:We retrospectively analyzed the frequency of MSAs and their association with clinical or ...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1080/14397595.2018.1452353
更新日期:2019-03-01 00:00:00
abstract::Skeletal injury is one of the most prevalent clinical problems that jeopardize the activities of daily life, especially in our aging society. Mesenchymal stem cells (MSCs) play pivotal roles in regenerating bones after bone injury. MSCs come from the surrounding tissues and/or circulation. Cell sources may be the bone...
journal_title:Modern rheumatology
pub_type: 杂志文章,评审
doi:10.1007/s10165-010-0357-8
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVES:A multicenter, randomized, double-blind, placebo-controlled study of the oral calcineurin inhibitor tacrolimus was performed in patients with early rheumatoid arthritis who had responded poorly to disease-modifying antirheumatic drugs (DMARDs), and factors related to suppression of joint destruction were inv...
journal_title:Modern rheumatology
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10165-012-0817-4
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVES:The aim of this study was to investigate the effect and potential mechanism of Cysteine-rich 61 (Cyr61) on stimulating MMP-3 expression by fibroblast-like synoviocytes (FLS) from rheumatoid arthritis (RA) patients. METHODS:Primarily cultured RA FLS were treated with exogenous Cyr61 protein or Cyr61-siRNA, t...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1080/14397595.2016.1220447
更新日期:2017-05-01 00:00:00