Postoperative complications in patients with rheumatoid arthritis using a biological agent - A systematic review and meta-analysis.

abstract：OBJECTIVES:The present study aimed to conduct an epidemiological survey of Central Sensitization Inventory (CSI) scores in an older adult population and to investigate the association between the CSI scores, age, sex, pain intensity, site of pain, and health-related quality of life (QOL). METHODS:Participants were 373...

journal_title：Modern rheumatology

authors： Ide K,Yasuda T,Hasegawa T,Yamato Y,Yoshida G,Banno T,Arima H,Oe S,Mihara Y,Ushirozako H,Yamada T,Watanabe Y,Nakai K,Hoshino H,Matsuyama Y

更新日期：2020-10-02 00:00:00

abstract：:Abstract We report on a 24-year-old woman with systemic lupus erythematosus and lupus anticoagulant who developed chronic thrombotic microangiopathic hemolytic anemia. The patient responded well to a combination of plasma exchange and anticoagulant therapy. Changes in the molecular markers for coagulation and fibrinol...

journal_title：Modern rheumatology

authors： Asanuma Y,Suzuki Y,Yasumuro Y,Ichikawa Y

更新日期：2000-12-01 00:00:00

abstract：:Methotrexate (MTX) is indispensable for the treatment of rheumatoid arthritis (RA). However, a small number of patients treated with MTX occasionally encounter some life-threatening events, including myelosuppression. Renal insufficiency, one of risk factors for these events, is difficult to assess because the serum c...

journal_title：Modern rheumatology

authors： Hayashi T,Ito S,Goto D,Matsumoto I,Sumida T

更新日期：2010-12-01 00:00:00

abstract：:Nintedanib (Ofev™), an oral triple kinase inhibitor targeting pro-fibrotic pathways, has been used for treatment of idiopathic pulmonary fibrosis (IPF). Based on positive results from phase III, placebo-controlled, randomized comparative clinical trial conducted in patients with systemic sclerosis-associated interstit...

journal_title：Modern rheumatology

authors： Kuwana M,Azuma A

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVES:To assess the efficacy of tocilizumab for preventing damage to the joints of systemic juvenile idiopathic arthritis (sJIA) patients, we examined serial radiographs of the hands and large weight-bearing joints of these patients before and after treatment with this agent. METHODS:Nine patients with sJIA recei...

journal_title：Modern rheumatology

authors： Inaba Y,Ozawa R,Aoki C,Imagawa T,Mori M,Hara R,Miyamae T,Saito T,Yokota S

更新日期：2013-07-01 00:00:00

abstract：:Research into the bone destruction associated with rheumatoid arthritis has highlighted the importance of the interplay of the immune and skeletal systems. Arthritic bone destruction is attributable to the defective control of osteoclastogenesis by T cells. We revealed that excessive expression of receptor activator o...

journal_title：Modern rheumatology

authors： Takayanagi H

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:Fractalkine (CX3CL1/FKN) is a chemokine that regulates chemotaxis and adhesion of CX3C chemokine receptor 1 (CX3CR1)-expressing inflammatory cells. We conducted the first phase 1/2, open-label, multiple ascending dose study of E6011, a humanized anti-FKN monoclonal antibody, in Japanese rheumatoid arthritis (...

journal_title：Modern rheumatology

authors： Tanaka Y,Takeuchi T,Umehara H,Nanki T,Yasuda N,Tago F,Kawakubo M,Kitahara Y,Hojo S,Kawano T,Imai T

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:Neutrophil extracellular traps (NETs) are peculiar structures composed of the externalized chromatin with intracellular proteins and formed by activated neutrophils in a reactive oxygen species (ROS)-dependent manner. Aberrant NETs are considered to be autoantigens for anti-neutrophil cytoplasmic antibodies (...

journal_title：Modern rheumatology

authors： Kimura H,Matsuyama Y,Araki S,Koizumi A,Kariya Y,Takasuga S,Eguchi S,Nakanishi H,Sasaki J,Sasaki T

更新日期：2018-05-01 00:00:00

abstract：:We examined the therapeutic effect of high molecular weight hyaluronic acid (HA) on the progression of joint pain and cartilage degeneration in a rabbit osteoarthritis (OA) model. The OA model was induced by partial meniscectomy. In the time course study, cartilage degeneration was assessed at 3, 7 and 14 days after o...

journal_title：Modern rheumatology

authors： Hashizume M,Koike N,Yoshida H,Suzuki M,Mihara M

更新日期：2010-10-01 00:00:00

abstract：:We performed this study to investigate the differences in radiological and laboratory findings between systemic juvenile idiopathic arthritis (s-JIA) and polyarthritis (p-JIA). Twenty-two patients with s-JIA and 18 with p-JIA were enrolled. Their laboratory findings and radiographs were examined retrospectively. Plain...

journal_title：Modern rheumatology

authors： Ozawa R,Inaba Y,Mori M,Hara R,Kikuchi M,Higuchi R,Miyamae T,Imagawa T,Fujiwara T,Saito T,Yokota S

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVES:Our primary objective was to retrospectively analyze whether bisphosphonates initiated in combination with immunosuppressive drugs and/or intravenous immunoglobulin (IVIG) resulted in a radiological and clinical improvement of dystrophic calcinosis in six female juvenile dermatomyositis (JDM) patients. METH...

journal_title：Modern rheumatology

authors： Tayfur AC,Topaloglu R,Gulhan B,Bilginer Y

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:To clarify the efficacy and safety of abatacept for secondary Sjögren's syndrome (SS) associated with rheumatoid arthritis (RA). METHODS:The primary endpoint of this open-labeled, prospective, observational multicenter study for secondary SS with RA was the remission rate of Simplified Disease Activity Index...

journal_title：Modern rheumatology

authors： Tsuboi H,Matsumoto I,Hagiwara S,Hirota T,Takahashi H,Ebe H,Yokosawa M,Yagishita M,Takahashi H,Kurata I,Ohyama A,Honda F,Asashima H,Miki H,Umeda N,Kondo Y,Hirata S,Saito K,Tanaka Y,Horai Y,Nakamura H,Kawakami A,

更新日期：2016-11-01 00:00:00

abstract：:The current study investigates the role of regulatory T (Treg) cells in the pathogenesis of ocular attack in patients with Behcet's disease (BD). Nineteen BD patients with ocular complications (BDo), including 11 BD patients with ocular attack (BDa) and eight BD patients with inactive ocular complications (BDi), were ...

journal_title：Modern rheumatology

authors： Nanke Y,Kotake S,Goto M,Ujihara H,Matsubara M,Kamatani N

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVE:Aspects of health-related quality of life (HRQoL) are important for assessing perceived health status and treatment burden. We evaluated HRQoL using Short Form 36 Health Survey (SF-36) and factors associated with HRQoL. METHODS:We collected basic and lifestyle-related, clinical, and treatment characteristics...

journal_title：Modern rheumatology

authors： Furukawa M,Kiyohara C,Horiuchi T,Tsukamoto H,Mitoma H,Kimoto Y,Uchino A,Nakagawa M,Oryoji K,Shimoda T,Akashi K

更新日期：2016-01-01 00:00:00

abstract：:A 20-year-old man presented with recurrent hemoptysis for seven months. A small subpleural nodule in his right lower lobe was found and excised surgically. Based on the presence of antiphospholipid antibodies (aPL) and vascular wall hypertrophy without vasculitis or an intraluminal thrombus, nonthrombotic proliferativ...

journal_title：Modern rheumatology

authors： Lee JS,Kim H,Lee EB,Song YW,Park JK

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVES:Joint space narrowing and osteophyte formation, radiographic features of knee osteoarthritis (OA), are not necessarily synchronous processes. We evaluated the relationship between medial minimum joint space width (mJSW) and osteophyte formation. METHODS:We conducted a retrospective study of 1050 individuals...

journal_title：Modern rheumatology

authors： Komatsu D,Hasegawa Y,Kojima T,Seki T,Higuchi Y,Ishiguro N

更新日期：2017-07-01 00:00:00

abstract：OBJECTIVE:To obtain safety and efficacy data on combination treatment with iguratimod and methotrexate (MTX) in an open-label extension study in patients with active rheumatoid arthritis (RA). METHODS:Following a 28-week, randomized, double-blind trial of adding iguratimod or placebo to stable MTX therapy, patients en...

journal_title：Modern rheumatology

authors： Hara M,Ishiguro N,Katayama K,Kondo M,Sumida T,Mimori T,Soen S,Nagai K,Yamaguchi T,Yamamoto K,Iguratimod-Clinical Study Group.

更新日期：2014-05-01 00:00:00

abstract：: ...

journal_title：Modern rheumatology

authors： Hatta Y,Hasegawa M,Matsushita T,Hamaguchi Y,Fujimoto M,Takehara K

更新日期：2013-04-27 00:00:00

abstract：OBJECTIVE:We examined the prevalence and risk factors of vertebral fracture in female Japanese patients with systemic lupus erythematosus (SLE). METHODS:We performed lateral radiographs of the thoracic and lumbar spine and bone mineral density (BMD) measurements and collected demographic, lifestyle, clinical, and trea...

journal_title：Modern rheumatology

authors： Furukawa M,Kiyohara C,Horiuchi T,Tsukamoto H,Mitoma H,Kimoto Y,Uchino A,Nakagawa M,Oryoji K,Shimoda T,Harada M,Akashi K

更新日期：2013-07-01 00:00:00

abstract：:Bucillamine (Bc) is a cysteine derivative with two SH groups, and a homolog of D-penicillamine, a disease-modifying antirheumatic drug (DMARD) widely used in Japan. However, it remains unclear whether Bc repairs bone erosion in patients with RA. Here, we treated three RA patients with Bc who subsequently showed radiog...

journal_title：Modern rheumatology

authors： Nanke Y,Iwatani M,Kobashigawa T,Yago T,Yamanaka H,Kotake S

更新日期：2009-01-01 00:00:00

abstract：:A 10-year cohort study was performed, involving all of the 118 patients treated with bucillamine in our hospital between 1988 and 1990. Evaluation was made on the basis of erythrocyte sedimentation rate, grip strength, joint score, duration of morning stiffness, and Lansbury index consisting of the above four paramete...

journal_title：Modern rheumatology

authors： Yokota N,Kuga Y,Kanazawa T,Morishita M,Tanida K,Itou K

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVES:To determine the availability of bioelectrical impedance analysis (BIA), computed tomography (CT), and magnetic resonance imaging (MRI) for measurement of skeletal muscle mass in patients with rheumatic diseases and quantitatively assess skeletal muscle loss after glucocorticoid (GC) treatment. METHODS:The ...

journal_title：Modern rheumatology

authors： Hosono O,Yoshikawa N,Shimizu N,Kiryu S,Uehara M,Kobayashi H,Matsumiya R,Kuribara A,Maruyama T,Tanaka H

更新日期：2015-03-01 00:00:00

abstract：:Objectives: Secondary central nervous system vasculitis (SCNSV) is an extremely rare, refractory, and fatal disease in patients with giant cell arteritis (GCA). We compared the characteristics of GCA patients with and without SCNSV.Methods: This retrospective, single-center, observational cohort study included 35 pati...

journal_title：Modern rheumatology

authors： Abe Y,Harada M,Tada K,Yamaji K,Tamura N

更新日期：2020-11-01 00:00:00

abstract：:Hyperimmunoglobulin E syndrome (HIES) is a primary immunodeficiency disorder with multisystem abnormalities including the vascular system. We report a child with autosomal recessive (AR)-HIES secondary to dedicator of cytokinesis 8 (DOCK8) deficiency who developed critical aortic aneurysm involving the ascending aorta...

journal_title：Modern rheumatology

authors： Al Mutairi M,Al-Mousa H,AlSaud B,Hawwari A,AlJoufan M,AlWesaibi A,AlHalees Z,Al-Mayouf SM

更新日期：2014-07-01 00:00:00

abstract：:A 24-year-old Japanese woman was admitted to our hospital suffering from high fever and progressive paralysis in both legs. Magnetic resonance imaging of the spinal cord showed high-intensity signals from C5 to Th4 and from Th7 to L1 on T2-weighted images. The patient was diagnosed as having acute transverse myelitis ...

journal_title：Modern rheumatology

authors： Yamanaka F,Migita K,Ichinose K,Ohno N,Kimura H,Ishimaru H,Matsuoka Y,Eguchi K,Ezaki H

更新日期：2005-01-01 00:00:00

abstract：:A female rheumatoid arthritis patient was admitted for productive cough and general fatigue that had gradually developed after leflunomide therapy. Side effects including severe hypoxia, thrombocytopenia, lymphocytopenia, and macrocytic anemia with schistocytes (probably drug-induced megaloblastic anemia) were noted. ...

journal_title：Modern rheumatology

authors： Toyokawa Y,Kingetsu I,Yasuda C,Yasuda J,Yoshida K,Kurosaka D,Yamada A

更新日期：2007-01-01 00:00:00

abstract：:Abstract Gout is a disease caused by an inflammatory response to an aggregation of monosodium urate crystals that develop secondary to hyperuricemia. Throughout its natural history it has four stages: asymptomatic hyperuricemia, acute gouty arthritis, intercritical gout, and chronic tophaceous gout. In this article, w...

journal_title：Modern rheumatology

authors： Tosun AK,Koca NT,Karataş GK

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVES:To assess the real-world effectiveness of golimumab in Japanese patients with rheumatoid arthritis who had previously received one or more biologic therapies. METHODS:A post-hoc analysis of post-marketing surveillance was performed. The clinical response to golimumab was analyzed in 1216 patients who had pr...

journal_title：Modern rheumatology

authors： Shimizu H,Kobayashi H,Kanbori M,Ishii Y

更新日期：2020-08-19 00:00:00

abstract：OBJECTIVES:To understand the status of mizoribine use in patients with lupus nephritis (LN) and to collect safety- and efficacy-related data on 2-year treatment with mizoribine. METHODS:A continuous survey was conducted between March 2010 and July 2015. RESULTS:The analysis set included 559 patients (mean age 39.5 ye...

journal_title：Modern rheumatology

authors： Takeuchi T,Okada K,Yoshida H,Yagi N

更新日期：2018-01-01 00:00:00

abstract：:We report the case of a 73-year-old man with myelodysplastic syndrome (MDS) who developed Weber-Christian disease (WCD). Bone marrow aspirates showed refractory anemia with abnormal karyotypes such as trisomy 8, trisomy 8 and 14, and trisomy 8, 9, and 14. The patient had intermittent fever associated with multiple ten...

journal_title：Modern rheumatology

authors： Hojo N,Hasegawa H,Iwamasa K,Hojo S,Fujita S

更新日期：2004-01-01 00:00:00