Abstract:
OBJECTIVES:To determine the availability of bioelectrical impedance analysis (BIA), computed tomography (CT), and magnetic resonance imaging (MRI) for measurement of skeletal muscle mass in patients with rheumatic diseases and quantitatively assess skeletal muscle loss after glucocorticoid (GC) treatment. METHODS:The data from 22 patients with rheumatic diseases were retrospectively obtained. The muscle mass of body segments was measured with a BIA device in terms of skeletal muscle mass index (SMI). Cross-sectional area (CSA) was obtained from CT and MRI scans at the mid-thigh level using the image analysis program. We further assessed the data of three different measurements before and after GC treatment in 7 patients with rheumatic diseases. RESULTS:SMI of whole body was significantly correlated with estimated muscle volume and mid-thigh muscle CSA with CT and MRI (p < 0.01). Significant correlations between SMI and mid-thigh muscle CSA of each leg were also found (p < 0.01). All the three measurements were negatively correlated with GC dosage (p < 0.01). Significant decline in mid-thigh muscle CSA with CT and MRI was found after GC treatment in 7 patients (p < 0.02). Those patients showed significant decline in SMI of whole body after GC treatment, but not in SMI of each leg. On the other hand, significant correlations between mid-thigh muscle CSA with CT and MRI were found before and after GC treatment (p < 0.01). CONCLUSIONS:GC-related skeletal muscle loss could be quantitatively assessed with BIA, CT, or MRI in patients with rheumatic diseases, and CT and MRI appeared to be more accurate than BIA.
journal_name
Mod Rheumatoljournal_title
Modern rheumatologyauthors
Hosono O,Yoshikawa N,Shimizu N,Kiryu S,Uehara M,Kobayashi H,Matsumiya R,Kuribara A,Maruyama T,Tanaka Hdoi
10.3109/14397595.2014.935078subject
Has Abstractpub_date
2015-03-01 00:00:00pages
257-63issue
2eissn
1439-7595issn
1439-7609journal_volume
25pub_type
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journal_title:Modern rheumatology
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journal_title:Modern rheumatology
pub_type: 临床试验,杂志文章
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pub_type: 杂志文章
doi:10.1007/s10165-012-0690-1
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pub_type: 杂志文章
doi:10.1080/14397595.2016.1208899
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pub_type: 杂志文章
doi:10.1007/s10165-004-0376-4
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,meta分析
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pub_type: 杂志文章,meta分析,评审
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更新日期:2015-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s10165-006-0462-x
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pub_type: 杂志文章
doi:10.1080/14397595.2019.1660027
更新日期:2020-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s10165-009-0241-6
更新日期:2010-04-01 00:00:00
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doi:10.1080/14397595.2020.1780076
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pub_type: 杂志文章
doi:10.3109/s101650170025
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pub_type: 杂志文章
doi:10.1007/s10165-011-0439-2
更新日期:2011-10-01 00:00:00
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journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1007/s10165-008-0065-9
更新日期:2008-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s10165-011-0469-9
更新日期:2011-12-01 00:00:00
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journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1007/s10165-009-0266-x
更新日期:2010-06-01 00:00:00
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journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1007/s10165-013-0877-0
更新日期:2013-04-12 00:00:00
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pub_type: 杂志文章,多中心研究
doi:10.1080/14397595.2017.1285857
更新日期:2017-11-01 00:00:00
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journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/s101650070020
更新日期:2000-09-01 00:00:00
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journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/14397595.2013.879416
更新日期:2014-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s10165-012-0735-5
更新日期:2013-07-01 00:00:00