Abstract:
:Objectives: The Childhood Health Assessment Questionnaire (CHAQ) is one of the most widely used self- report questionnaires to measure functional status in Juvenile idiopathic arthritis (JIA). The Japanese version of the CHAQ (JCHAQ) has been revised to meet requirements of clinical international trials which need the same number of questions in each functional area of the CHAQ.Methods: The original JCHAQ consisted of 36 items, measuring eight functional areas. This was changed to 30 items of questionnaire so that each functional area has same number of questions as the original US English version. The revised version was professionally translated from English to Japanese, reviewed, and validated with Japanese JIA patients.Results: A total of 42 JIA patients were enrolled in the validation: seven systemic, 30 polyarticular/oligoarticular and five enthesis related. Most patients were well controlled and the median disability index (DI) scores was 0.0 [0-0.03]; however, significant correlation was seen with visual analog scale (VAS) of pain, VAS overall well-being, physician VAS, DAS (Disease Activity Score) 28-ESR, and JADAS (Juvenile Arthritis Disease Activity Score)-27. In comparison of two groups of disease activity, remission or inactive/low disease activity vs. moderate/high disease activity, both DAS28-ESR and JADAS-27 showed significant correlation with DI.Conclusion: The updated JCHAQ was a reliable and valid tool for the functional assessment of children with JIA. It is more suitable for international and transitional comparison.
journal_name
Mod Rheumatoljournal_title
Modern rheumatologyauthors
Miyamae T,Tani Y,Kishi T,Yamanaka H,Singh Gdoi
10.1080/14397595.2019.1660027subject
Has Abstractpub_date
2020-09-01 00:00:00pages
905-909issue
5eissn
1439-7595issn
1439-7609journal_volume
30pub_type
杂志文章abstract:OBJECTIVE:The prediction of hip osteoarthritis (OA) progression is still a difficult issue. We have adopted (18)F-fluoride positron emission tomography (PET) for the evaluation of hip osteoarthritis, and investigated the prediction utility of (18)F-fluoride PET for both pain worsening and OA progression using a logisti...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/14397595.2015.1045257
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVES:A self-administered foot evaluation questionnaire (SAFE-Q) was developed by the Japanese Society for Surgery of the Foot (JSSF). The aim of this study is to evaluate the validity and responsiveness of the SAFE-Q in patients with rheumatoid arthritis (RA). METHODS:In total, 180 patients with RA answered the ...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/14397595.2014.959243
更新日期:2015-05-01 00:00:00
abstract::Periaortitis and periarteritis are one of the clinical features of IgG4-related disease. Such vascular manifestations are reported to be present in 10-30% of overall IgG4-related disease, and they may also appear as an isolated lesion of IgG4-related disease. As other types of large vessel vasculitis, IgG4-related vas...
journal_title:Modern rheumatology
pub_type: 杂志文章,评审
doi:10.1080/14397595.2018.1546367
更新日期:2019-03-01 00:00:00
abstract::Abstract We report the case of a 52-year-old man with Wegener's granulomatosis complicated with seropneumothorax. Pneumothorax or seropneumothorax has previously been reported as a rare complication of Wegener's granulomatosis. The patient was successfully treated with prednisolone and cyclophosphamide, and seropneumo...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/s10165-002-0220-7
更新日期:2003-06-01 00:00:00
abstract::Pneumatosis cystoides intestinalis (PCI), which is characterized by the presence of multiple gas-filled mucosal, submucosal, or subserosal cysts located throughout the colon and/or small intestine, is an unusual complication of systemic lupus erythematosus (SLE). We report a case of a 33-year-old woman with a 5-year h...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1007/s10165-005-0437-3
更新日期:2005-01-01 00:00:00
abstract::Cutaneous polyarteritis nodosa (CPAN) is a form of necrotizing vasculitis of small and medium-sized arteries. It is limited to the skin and has a recurrent and chronic course, possibly associated with fever, arthralgia, myalgia and neuropathy, but without visceral involvement. We report the clinical case of a 7-year-o...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/14397595.2013.874737
更新日期:2014-07-01 00:00:00
abstract::We report a patient who had a 4-year history of adult-onset Still's disease (AOSD) and showed a prominent increase in large granular lymphocytes (LGL) when she developed severe Pseudomonas conjunctivitis due to Pseudomonas aeruginosa, skin eruptions, liver damage, and abnormal findings in coagulation studies, without ...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1007/s10165-006-0462-x
更新日期:2006-01-01 00:00:00
abstract::Objectives: Overactive bladder (OAB) is a clinical diagnosis defined with the presence of urinary urgency, usually accompanied by frequency and nocturia, with or without urgency urinary incontinence. Objective was to evaluate the demographic and clinical characteristics of Japanese systemic sclerosis (SSc) patients wi...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1080/14397595.2019.1589913
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVES:The objective of this study is to clarify the surgical indication for rheumatoid forefoot deformity according to background characteristics and plantar pressure. METHODS:Patients with rheumatoid arthritis were divided into a non-surgical group (group N) and a surgical group (group S). The former consisted o...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1080/14397595.2017.1301015
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVES:Gout is a polygenic auto-inflammatory disease, in which inflammation plays an important role in disease pathogenesis. The cytokine interleukin (IL)-23 promotes inflammation and helps to guide inflammatory cells, while studies have shown that the IL-23R gene is associated with susceptibility to several immune...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/14397595.2014.964823
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVE:To examine the deterioration of interstitial lung disease (ILD) in patients with rheumatoid arthritis (RA) treated with abatacept over the long-term. METHODS:We examined 131 patients with RA who had been treated with abatacept for more than 1 year. All patients underwent high-resolution computed tomographic ...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1080/14397595.2018.1481566
更新日期:2019-05-01 00:00:00
abstract::Tumor necrosis factor (TNF) plays an important role in the host defense mechanism, and anti-TNF antibody therapies may increase the risk of serious infections. We herein report a case of 57-year-old male with rheumatoid arthritis who developed brucellosis during treatment with infliximab in combination with methotrexa...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1007/s10165-010-0388-1
更新日期:2011-06-01 00:00:00
abstract:OBJECTIVES:To assess gout and asymptomatic hyperuricemia in Japan and review treatment conditions. METHODS:This retrospective cross-sectional study analyzed the prevalence of hyperuricemia and gout, and characteristics and treatment of patients with those conditions, using Japanese health insurance claims and medical ...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1080/14397595.2020.1784556
更新日期:2021-01-01 00:00:00
abstract::Abstract To determine the specificities of autoantibodies targeting cell cycle-associated antigens in rheumatic diseases, we studied 30 sera which were obtained from patients visiting our hospital and which exhibited a variegated speckled pattern in indirect immunofluorescence (IF). The immunoreactivities of the sera ...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/s101650170008
更新日期:2001-09-01 00:00:00
abstract::Synovial vascularization in the knee joints of six patients with rheumatoid arthritis who were treated with infliximab was evaluated by Doppler sonography. Power Doppler sonography demonstrated a significant reduction of color flow signals (P < 0.05), and spectral Doppler sonography demonstrated a significant increase...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1007/s10165-004-0359-5
更新日期:2005-01-01 00:00:00
abstract::The aim of this study was to investigate the reliability and the validity of the Japanese version of the 2010 American College of Rheumatology Preliminary Diagnostic Criteria for Fibromyalgia (ACR 2010-J), and its quantification scale, the Fibromyalgia Symptom Scale (FS-J). In this study, we divided patients with chro...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1007/s10165-011-0462-3
更新日期:2012-02-01 00:00:00
abstract::The most representative kidney lesion of IgG4-related disease (IgG4-RD) is plasma cell-rich tubulointerstitial nephritis (TIN) with distinctive imaging findings including multiple low-density lesions on contrast-enhanced computed tomography. In addition, membranous glomerulonephritis is a representative glomerular les...
journal_title:Modern rheumatology
pub_type: 杂志文章,评审
doi:10.1080/14397595.2018.1554321
更新日期:2019-03-01 00:00:00
abstract::Objectives: To assess the middle-term outcome of iguratimod (IGU) in rheumatoid arthritis (RA) patients. Methods: Sixty-nine RA patients (14 males and 55 females, mean age of 64.0 years) receiving IGU-containing therapies were enrolled. We divided these patients into three groups based on the treatment at the baseline...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1080/14397595.2018.1510879
更新日期:2019-09-01 00:00:00
abstract::Objective: This study aimed to clarify whether plasma acrolein level actually increases in rheumatoid arthritis (RA) patients, and to elucidate whether any relationship exists between the levels and the RA background variables.Methods: Plasma levels of protein-conjugated acrolein (PC-Acro) in 84 patients (RA group) an...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1080/14397595.2020.1775921
更新日期:2020-06-16 00:00:00
abstract:OBJECTIVES:To establish a new assessment tool for ulnar drift (UD) in rheumatoid arthritis (RA). METHODS:We established an observational cohort of 67 patients (134 rheumatoid hands) beginning in 2004. Fifty-two patients (100 hands) had follow-up in 2009 and 37 patients (63 hands) completed follow-up in 2015. UD was ev...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1080/14397595.2018.1442171
更新日期:2019-01-01 00:00:00
abstract::Abstract The human major histocompatibility complex (MHC) class I gene HLA-B27 bears a striking association with ankylosing spondylitis and related spondyloarthropathies. This association transcends all ethnic and geographical boundaries. The primary function of HLA-B27 as an MHC class I protein is to form a complex w...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/s10165-001-8056-0
更新日期:2001-12-01 00:00:00
abstract:OBJECTIVES:Anti-cytokine therapy is reportedly useful in amyloid A (AA) amyloidosis complicating rheumatic diseases. However, to date no studies have directly compared the utility of tumour necrosis factor (TNF) inhibition to that of interleukin-6. The aim of our retrospective study was to compare the clinical utility ...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/14397595.2013.854048
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:To assess the long-term safety, immunogenicity, and efficacy of subcutaneous (SC) abatacept in combination with methotrexate (MTX) in Japanese patients with rheumatoid arthritis who were MTX inadequate responders, in a long-term extension (LTE) to a double-dummy, double-blind study (NCT01001832). METHODS:Pat...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/14397595.2015.1012786
更新日期:2015-09-01 00:00:00
abstract::Objectives: In this study, we aimed to evaluate the level of central sensitization (CS) and its relationship with health profile, including neuropathic pain and sleep quality in Behçet's disease (BD).Method: Eighty-eight patients with BD and 60 healthy controls (HCs) were included in the study between May 2018 and Feb...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1080/14397595.2020.1780076
更新日期:2020-07-06 00:00:00
abstract::Objective: We conducted a questionnaire survey within a standard clinical setting to clarify that picture superiority effect (PSE) could be obtained by musculoskeletal ultrasound (MSKUS) examination.Methods: One hundred patients with rheumatoid arthritis or arthralgia, who visited the Rheumatology Unit, Department of ...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1080/14397595.2019.1645382
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:The international classification criteria (CC) for definite antiphospholipid syndrome (APS) recommend confirmation of the sustained presence, for at least 12 weeks, of both lupus anticoagulant (LA), as determined by aPTT and RVVT, and anti β2glycoprotein I (β2GPI) or anticardiolipin (aCL) IgG and/or IgM. Howe...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/14397595.2015.1023978
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVES:To evaluate the scoring of whole-body magnetic resonance imaging (WBMRI) for efficacy assessment in rheumatoid arthritis (RA) patients receiving biological disease-modifying anti-rheumatic drugs (bDMARDs). METHODS:Thirty consecutive RA patients receiving bDMARDs were included in this retrospective study. Co...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1080/14397595.2016.1276425
更新日期:2017-11-01 00:00:00
abstract::A postoperative lung cancer patient presented with lymphadenopathy, pleural thickening, and 18F-fluorodeoxyglucose (FDG) uptake on a positron emission tomography-computed tomography (PET-CT) scan. Lung cancer recurrence was initially suspected, but bilateral submandibular masses with 18F-FDG uptake indicated the possi...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1007/s10165-011-0580-y
更新日期:2012-09-01 00:00:00
abstract::Aortitis, inflammation of the aortic tissue, is most commonly caused by vasculitic rheumatic conditions, and less frequently infectious organisms. Involvement of the aorta is well defined in HLA-B27-associated spondyloarthropathies such as long-standing ankylosing spondylitis and Reiter's syndrome. However, unlike oth...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.1007/s10165-011-0566-9
更新日期:2012-09-01 00:00:00
abstract::Abstract Methotrexate (MTX) is the most commonly used disease-modifying antirheumatic drug (DMARD) throughout the world. In Japan, MTX is recommended by the Japanese Ministry of Health, Labour, and Welfare to be given as the second or third DMARD and at a dosage of no more than 8 mg/week. We analyzed the efficacy of M...
journal_title:Modern rheumatology
pub_type: 杂志文章
doi:10.3109/s10165-004-0340-3
更新日期:2004-12-01 00:00:00